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战略性新兴产业的培育和发展——首届云南省科协学术年会

作者： tran minh hau 陈明厚 School of Material Science and Engineering Kunming University of Science and Technology

The Bi-Tm co-doped SiO-AlO-LaO(SAL) glasses,which exhibited a broadband near-infrared emission was investigated by the optical absorption and photoluminescence *** super broadband near-infrared emission from 1000 to 2100 nm,covering the whole O,E,S,C,and L bands,was observed in the Bi-Tm co-doped samples,as a result of the overlap of the Bi-related emission band(centered at 1270 nm) and the emission from Tm H→F transition(1440 nm) as well as Tm F→H transition(1800 nm).Relative luminescence intensity at 1270,1440 and 1800 nm wavelength varies depending on the mixing ratio of Bi and Tm,and the full width at half-maximum(FWHM) extending from 1000 to 1600 could be 400 *** results indicated that Bi-Tm co-doped SiO-AlO-LaO glasses could provide potential applications in tunable lasers as well as the broadband optical amplifiers in WDM system.

关键词： Silica glass Energy transfer Bi-Tm co-doped Luminescence Broadband

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Up-conversion of Er^(3+)/Yb^(3+)co-doped transparent glass-ceramics containing Ba_2LaF_7 nanocrystals

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Journal of Rare Earths 2013年第9期31卷 843-848页

作者：胡金民周大成王荣飞陈明厚焦清余雪邱建备 School of Materials Science and Engineering Kunming University of Science and Technology Department of Research Admini stration and International Relations Tuyhoa Industrial College

The up-conversion of Er3＋/yb3＋ co-doped transparent glass-ceramics 50SiO2-10A1F3-5TiO2-30BaF2-4LaF3-0.5ErF3-0.5YbF3 containing Ba2LaF7 nanocrystals under the changing of heat treatment temperature and time were investigated. The Ba2LaF7 nanocrystals precipitated from the glass matrix was confirmed by X-ray diffraction （XRD）. The structural investigation carried out by XRD and trans- mission electron microscopy （TEM） evidenced the formation of cubic Ba2LaF7 nanocrystals with crystal size of about 14 nm. Comparing with the samples before heat treatment, the high efficiency up-conversion emission of Er3＋/Yb3＋ co-doped samples was observed in the glass-ceramics under 980 nm laser diode excitation. The increase in red emission intensity bands was stronger than the green bands when the crystal size increased. The mechanism for the up-conversion process in the glass-ceramics and the reasons for the increase of Er3＋/yb3＋ co-doped up-conversion intensity after heat treatment were discussed.

关键词： up-conversion BazLaF7 nanocrystals glass-ceramics rare earths

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20-Hydroxyecdysone from Dacrycarpus imbricatus bark inhibits the proliferation of acute myeloid leukemia cells

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Asian Pacific Journal of Tropical Medicine 2017年第2期10卷 151-153页

作者： Trinh Thi Thuy Nguyen Thanh Tam Nguyen Thi Hoang Anh Dang Viet hau Dinh Thi Phong Le Quoc Thang Sabrina Adorisio tran Van Sung Domenico V Delfino Institute of Chemistry Vietnam Academy of Science and Technology Vietnam National Museum of Nature Vietnam Academy of Science and Technology Hue University’s College of Educations Section of Pharmacology Department of MedicineUniversity of Perugia

Objective:To investigate the anti-proliferative effects of 20-hydroxyecdysone isolated from the bark of Dacrycarpus imbricatus(Blume) de ***:Column chromatography was used for isolation of compounds from plant *** structure of the isolated compound was identified by mass spectrometry and nuclear magnetic resonance techniques,including HSQC,HMBC,NOE-difference *** isolated compound was tested for its anti-proliferative activity in acute myeloid leukemia(AML) and OCI-AML ***:Compound 1 was isolated from the ethyl acetate fraction of Dacrycarpus imbricatus barks by column *** chemical structure was identified as 20-hydroxyecdysone(20HE),a cholestane-type ecdysteroid,by a combination of mass spectrometry and nuclear magnetic resonance spectrometric *** goal was to test the anti-proliferative activity of 20 HE using the OCI-AML cell line.20 HE significantly decreased OCI cell number at a concentration of 1 mg/mL,whereas lower concentrations were ***,this decrease was due to partial blockage of the G_1/S phase of the cell cycle,with a reduction of cells in the G_2M phase,not due to increased ***:This indicates that 20 HE significantly decreases the number of cells in the G_1/S phase of the cell cycle in human AML *** is the first time that the anti-proliferative activity of 20 HE against a human tumor cell line has been reported.

关键词： Dacrycarpus imbricatus Ecdysteroid 20-hydroxyecdysone Proliferation Acute myeloid leukemia

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Effect of Temperature Dependence on Electrical Characterization of <i>p-n</i>GaN Diode Fabricated by RF Magnetron Sputtering

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Materials Sciences and Applications 2015年第9期6卷 809-817页

作者： Thi tran Anh Tuan Dong-hau Kuo Cheng-Che Li Guan-Zhang Li Department of Materials Science and Engineering National Taiwan University of Science and Technology Taiwan School of Basic Sciences Tra Vinh University Tra Vinh Vietnam

The p-n junction GaN diodes were all fabricated by sputtering technique with cermet targets for p- and n-type GaN and metal targets for electrodes. The interface of these p-n junction GaN diodes examined by high-resolution transition electron microscopy was clear and distinguishable. Lattice images identified the complete dissolution of Mg into the Ga site. At the room temperature, the diode had the turn-on voltage of 2.2 V, the leakage current of 2.2 × 10–7 A, the breakdown voltage of –6 V, the barrier height of 0.56 eV, ideality factor of 5.0 by I (current)-V (voltage) test and 5.2 derived from the Cheungs’ method, and series resistance of 560 Ω. These electrical properties were investigated at different testing temperatures from room temperature to 200°C. The temperature dependence in the I-V characteristics of the p-n diodes can be successfully explained on the basis of thermionic-emission mode.

关键词： p-n GaN Diode I-V Measurement Barrier Height Leakage Current Cheungs’ Method

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Tissue engineering using mesenchymal stem cells with periosteal wrap for bone defect repair in rabbits

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Plastic and Aesthetic Research 2015年第1期2卷 340-345页

作者： Trung-hau LêThua Dang-Nhat Pham Khanh-Linh Lê minh-Tuan Lê Quang-Ton-Quyen Nguyen Phan-Huy Nguyen Ngoc-Vu tran Ngoc-Luong Nguyen Willy Boeckx Albert Demey Department of Plastic Reconstructive and Hand SurgeryCenter of Orthopaedic and Plastic SurgeryHue Central HospitalHue City 531120Vietnam Department of Hematology Hue Central HospitalHue City 531120Vietnam Department of Biology College of SciencesHue UniversityHue City 521120Vietnam Department of Plastic Surgery Brugmann University HospitalUniversitélibre de Bruxelles1020 BrusselsBelgium

Aim:Mesenchymal stem cells(MSCs)are an excellent potential source of cells for bone tissue engineering due to their excellent renewal ability and osteogenic differentiation *** study was designed to evaluate the bone formation properties of a demineralized cancellous bone scaffold seeded with MSCs,with or without periosteum,in a critical size bone defect model in ***:Rabbit culture-expanded bone marrow(BM)-MSCs were seeded onto a human demineralized cancellous bone(HDCB)*** defects measuring 15 mm in length were created in each radius.A total of 56 bone defects in 28 rabbits were randomly assigned to one of the 4 groups for scaffold implantation:Group 1:HDCB graft only;Group 2:periosteum-wrapped HDCB graft;Group 3:HDCB graft seeded with BM-MSCs and Group 4:periosteum-wrapped HDCB graft seeded with *** rabbits were sacrificed 12 weeks after surgery for gross observation,radiological assessment,histological analyses and biomechanical ***:New bone(NB)formation and bone healing were successfully achieved,both radiologically and histologically,on demineralized cancellous bone graft seeded with *** were improved when BM-MSCs were associated with ***:This study demonstrates that repair of bone defects in a rabbit model can be achieved through bone grafting using BM-MSCs,implanted on a demineralized cancellous bone *** formation of NB was optimized when combined with the preservation of periosteum at the site of injury.

关键词： Bone defects bone marrow bone tissue engineering mesenchymal stem cells periosteum

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Material and Device Developments of p/n Ⅲ-Nitrde Thin Films made by Low-Temperature Sputtering

Material and Device Developments of p/n Ⅲ-Nitrde Thin Films...

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第二届海峡两岸功能材料科技与产业峰会（2015）

作者： Dong-hau Kuo Thi tran Anh Tuan Cheng-Che Li Wei-Chun Yen Department of Materials Science and Engineering "National Taiwan University of Science and Technology"

GaN and In GaN layers have been deposited by metal-organic vapor deposition(MOCVD)and molecular beam *** MOCVD,In GaN films grown at 550-900 oC use trimethylindium(TMIn),trimethylgallium(TMGa),and NH as reaction precursors and N as carrier *** high capital cost and process temperature and the utilization of dangerous precursors are the major concerns of MOCVD process.p-Ga N films grown at 1000

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2021皮肤红斑狼疮的诊断、治疗和长期管理指南

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中国合理用药探索 2022年第10期19卷 27-40页

作者： Qianjin Lu Hai Long Steven Chow Syarief Hidayat Retno Danarti Yulianto Listiawan Danqi Deng Qing Guo Hong Fang Juan Tao Ming Zhao Leihong Xiang Nan Che Fen Li Hongjun Zhao Chak Sing Lau Fong Cheng Ip King Man Ho Arnelfa C.Paliza Chan Vicheth Kiran Godse Soyun Cho Chew Swee Seow Yoshiki Miyachi tran hau Khang Rataporn Ungpakorn Hassan Galadari Rashmikant Shah Kehu Yang Youwen Zhou Carlo Selmi Amr HSawalha Xuan Zhang Yaolong Chen Chrang-Shi Lin 姚文鑫不详首都医科大学附属北京世纪坛医院药学部北京100038

皮肤红斑狼疮(CLE)是一种炎症性自身免疫性疾病,其分型较多,包括急性、亚急性、慢性和间歇性CLE。其中,慢性CLE可以进一步分为红斑狼疮(LE)的几个亚型,如盘状LE、疣状LE、深在性LE、冻疮样LE和Blaschko线状LE等。为了给皮肤科医生和风... 详细信息

皮肤红斑狼疮(CLE)是一种炎症性自身免疫性疾病,其分型较多,包括急性、亚急性、慢性和间歇性CLE。其中,慢性CLE可以进一步分为红斑狼疮(LE)的几个亚型,如盘状LE、疣状LE、深在性LE、冻疮样LE和Blaschko线状LE等。为了给皮肤科医生和风湿科医生提供CLE的诊断、治疗和长期管理的实用指导建议,本证据和共识指南根据卫生保健实践指南的报告条目(国际RIGHT工作组)目录编制,并在国际实践指南注册平台注册。在亚洲皮肤科学会(ADA)、亚洲皮肤病性病学会(AADV)以及中华医学会皮肤性病学分会(CSD)红斑狼疮研究中心的共同努力下,来自亚洲、美洲、欧洲等16个国家或地区的25名皮肤科医生、7名风湿科医生、1名红斑狼疮领域专家和2名方法学家参与了本指南的制定。所有建议均取得了32名医生中至少80%的同意。作为共识,CLE的诊断主要基于临床和组织病理学表现的评估,并且通过对全身多系统损伤的评估,排除系统性红斑狼疮(SLE)。外用糖皮质激素和钙调磷酸酶抑制剂是局部CLE的一线治疗。对于泛发或严重的CLE皮损和/或局部耐药的病例,可以合并全身治疗,包括抗疟药和/或短期全身使用糖皮质激素。值得注意的是,抗疟药是所有类型CLE的一线全身治疗药物,同样可用于妊娠期患者和儿童。二线治疗用药包括沙利度胺、类维生素A类药物、氨苯砜和甲氨蝶呤,而霉酚酸酯是三线治疗用药。最后,脉冲染料激光或手术可作为四线治疗,用于局部以及发生在不可修饰部位的慢性、难治性CLE皮损。贝利尤单抗亦可作为四线治疗用药,用于活动性SLE患者的泛发性CLE皮损或糖皮质激素逐渐减量期间复发的急性CLE。对于疾病的管理,患者教育和长期随访是必要的。建议在每次随访时适当评估疾病活动度、皮肤和其他器官损伤、生活质量、合并症及可能发生的不良事件。

关键词：红斑狼疮共识循证妊娠期儿童脉冲染料激光

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