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Supramolecular G-quadruplex hydrogels:Bridging fabrication to biomedical application

Journal of Materials Science & Technology 2023年第24期155卷 238-252页

作者： Yuanfeng Li Junjie Chi Pingwei Xu Xing Dong anh-tuan Le Keqing Shi Yong Liu Jian Xiao translational Medicine Laboratory The Center of Wound Healing and Regenerative Medicine the First Affiliated Hospital of Wenzhou Medical University Zhejiang 325035 China School of Pharmaceutical Sciences Key Laboratory of Biotechnology and Pharmaceutical Engineering The Center of Wound Healing and Regenerative Medicine the First Affiliated Hospital Wenzhou Medical University Zhejiang 325035 China Wenzhou Institute University of Chinese Academy of Sciences Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine Vision and Brain Health) Engineering Research Center of Clinical Functional Materials and Diagnosis & Treatment Devices of Zhejiang Province Zhejiang 325001 China Phenikaa University Nano Institute (PHENA) Phenikaa University Hanoi 12116 Viet Nam

G-quadruplex hydrogel is a class of self-assembled supramolecular hydrogel formed by guanine *** a biomimetic hydrogel,G-quadruplex hydrogels demonstrate wide biomedical applications,such as drug delivery,tissue engineering,and *** advantages of using G-quadruplex hydrogels include adequate biocompatibility and biodegradability,tunable multifunctionality,and cost-effective and large-scalable fabrication *** this review,we focus on recent progress in the fabrication and characterization of G-quadruplex hydrogels to help readers understand the principles of G-quadruplex hydrogel ***,the applications of G-quadruplex hydrogels in the biomedical area are discussed,aiming to pave the way for downward clinical or industry *** development of G-quadruplex hydrogel is still in its *** hope this review will boost the development of this area and that more applications of G-quadruplex hydrogel will be developed.

关键词： Guanosine DNA hydrogel Self-assembly Drug delivery Tissue engineering

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Adaptive data fusion framework for modeling of non-uniform aerodynamic data

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Chinese Journal of Aeronautics 2023年第7期36卷 316-336页

作者： Vinh PHAM Maxim TYAN tuan anh NGUYEN Chi-Ho LEE L.V.Thang NGUYEN Jae-Woo LEE Department of Aerospace Information Engineering Konkuk UniversitySeoul 05029Republic of Korea Konkuk Aerospace Design-Airworthiness Institute Konkuk UniversitySeoul 05029Republic of Korea

Multi-fidelity Data Fusion(MDF)frameworks have emerged as a prominent approach to producing economical but accurate surrogate models for aerodynamic data modeling by integrating data with different fidelity ***,most existing MDF frameworks assume a uniform data structure between sampling data sources;thus,producing an accurate solution at the required level,for cases of non-uniform data structures is *** address this challenge,an Adaptive Multi-fidelity Data Fusion(AMDF)framework is proposed to produce a composite surrogate model which can efficiently model multi-fidelity data featuring non-uniform ***,the design space of the input data with non-uniform data structures is decomposed into subdomains containing simplified ***,different MDF frameworks and a rule-based selection process are adopted to construct multiple local models for the subdomain *** the other hand,the Enhanced Local Fidelity Modeling(ELFM)method is proposed to combine the generated local models into a unique and continuous global ***,the resulting model inherits the features of local models and approximates a complete database for the whole design *** validation of the proposed framework is performed to demonstrate its approximation capabilities in(A)four multi-dimensional analytical problems and(B)a practical engineering case study of constructing an F16C fighter aircraft’s aerodynamic *** comparisons of the generated models using the proposed AMDF framework and conventional MDF approaches using a single global modeling algorithm are performed to reveal the adaptability of the proposed approach for fusing multi-fidelity data featuring non-uniform ***,the results indicated that the proposed framework outperforms the state-of-the-art MDF approach in the cases of non-uniform data.

关键词： Aerodynamic modeling Data fusion Diverse data structure Multi-fidelity data Multi-fidelity surrogate modeling

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LiMn_2O_4/CNTs and LiNi_(0.5)Mn_(1.5)O_4/CNTs Nanocomposites as High-Performance Cathode Materials for Lithium-Ion Batteries

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Acta Metallurgica Sinica(English Letters) 2015年第1期28卷 122-128页

作者： Thang Van Le Ha tran Nguyen anh tuan Luu Man Van tran Phung Loan My Le Faculty of Materials Technology Ho Chi Minh University of Technology 268 Ly Thuong Kiet Ward 14 District 10 Ho Chi Minh City Vietnam Department of Physical Chemistry University of Science VNUHCM 227 Nguyen Van Cu Street District 5 Ho Chi Minh CityVietnam

The demand of higher energy density and higher power capacity of lithium（Li）-ion secondary batteries has led to the search for electrode materials whose capacities and performance are better than those available today. Carbon nanotubes（CNTs）, with their unique properties such as 1D tubular structure, high electrical and thermal conductivities, and extremely large surface area, have been used as materials to prepare cathodes for Li-ion batteries. The structure and morphology of CNTs were analyzed by X-ray diffraction（XRD）, scanning electron microscopy（SEM）, and transmission electron microscopy（TEM）. The functional groups on the purified CNT surface such as –COOH, –OH were characterized by Fourier transform infrared spectroscopy. The electrode materials were fabricated from LiMn2O4（LMO）, doped spinel LiNi0.5Mn1.5O4, and purified CNTs via solid-state reaction. The structure and morphology of the electrode were characterized using XRD, SEM, and TEM. Finally, the efficiency of the electrode materials using CNTs was evaluated by cyclic voltammetry and electrochemical impedance spectroscopy.

关键词： Nanocomposites Carbon nanotubes(CNTs) Spinel materials Lithium-ion batteries(LIBs)

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Deep learning long short-term memory combined with discrete element method for porosity prediction in gravel-bed rivers

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International Journal of Sediment Research 2023年第1期38卷 128-140页

作者： Duong tran anh Ahad Hasan Tanim Daniel Prakash Kushwaha Quoc Bao Pham Van Hieu Bui HUTECH University Center for River Harbor and Landslide Research Chittagong University of Engineering & Technology Govind Ballabh Pant University of Agriculture and Technology Institute of Applied Technology Thu Dau Mot University Faculty of Mechanical Engineering Thuyloi University

The porosity of gravel riverbed material often is an essential parameter to estimate the sediment transport rate, groundwater-river flow interaction, river ecosystem, and fluvial geomorphology. Current methods of porosity estimation are time-consuming in simulation. To evaluate the relation between porosity and grain size distribution(GSD), this study proposed a hybrid model of deep learning Long Short-Term Memory(LSTM) combined with the Discrete Element Method(DEM). The DEM is applied to model the packing pattern of gravel-bed structure and fine sediment infiltration processes in threedimensional(3D) space. The combined approaches for porosity calculation enable the porosity to be determined through real time images, fast labeling to be applied, and validation to be done. DEM outputs based on the porosity dataset were utilized to develop the deep learning LSTM model for predicting bed porosity based on the GSD. The simulation results validated with the experimental data then segregated into 800 cross sections along the vertical direction of gravel pack. Two DEM packing cases, i.e., clogging and penetration are tested to predict the porosity. The LSTM model performance measures for porosity estimation along the z-direction are the coefficient of determination(R~2), root mean squared error(RMSE), and mean absolute error(MAE) with values of 0.99, 0.01, and 0.01 respectively, which is better than the values obtained for the Clogging case which are 0.71, 0.14, and 0.03, respectively. The use of the LSTM in combination with the DEM model yields satisfactory results in a less complex gravel pack DEM setup, suggesting that it could be a viable alternative to minimize the simulation time and provide a robust tool for gravel riverbed porosity prediction. The simulated results showed that the hybrid model of the LSTM combined with the DEM is reliable and accurate in porosity prediction in gravel-bed river test samples.

关键词： Numerical modeling Discrete element method LSTM Bed porosity Gravel-bed river

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Study of vertically ascending flight of a hawkmoth model

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Acta Mechanica Sinica 2020年第5期36卷 1031-1045,I0002页

作者： anh tuan Nguyen Vu Dan Thanh Le The Hung tran V.N.Due Van Binh Phung Faculty of Aerospace Engineering Le Quy Don Technical UniversityHanoiVietnam Institute of Theoretical and Applied Research.Duy Tan University HanoiVietnam Division of Construction Computation Institute for Computational ScienceTon Due Thang UniversityHo Chi Minh CityVietnam Faculty of Civil Engineering Ton Due Thang UniversityHo Chi Minh CityVietnam

This paper provides insight into the wing kinematics,the power requirement and the dynamic stability characteristics of a hawkmoth model in vertically ascending *** wing kinematics of the hawkmoth model is obtained based on the minimum required power *** optimization process is conducted using genetic and simplex algorithms that are coupled with an artificial neural network to rapidly predict the aerodynamic force and required *** training data for the neural network are generated from an unsteady vortex-lattice *** to hover,the results in this study show the larger flapping frequency and the smaller rotation amplitude of the hawkmoth wing kinematics in ascending ***,more power is required when the ascending speed *** conducting a dynamic modal analysis based on a cycle-average approach,the certain effect of the ascending speed on the modal structures of the hawkmoth model was observed.

关键词： Hawkmoth Ascending flapping flight-Genetic algorithm Artificial neural network Flight dynamic stability

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Embryonic, genetic and clinical outcomes of fresh versus vitrified oocyte: A retrospective cohort study

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Asian pacific Journal of Reproduction 2023年第6期12卷 266-272页

作者： Phuong Dao Thi Son Dang Truong Thuan Nguyen Duc anh Pham Van anh Do tuan Van Hanh Nguyen HP Fertility-Hai Phong International Hospital of Obstetrics and Pediatrics Haiphong180000Vietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoi100000Vietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoi100000Vietnam

Objective:To compare embryonic development,ploidy status and clinical outcomes between fresh and frozen-thawed ***:This retrospective cohort study evaluated 83 fertilization cycles including both fresh and frozen oocytes from 79 patients at the HP Fertility Center of Hai Phong International Hospital of Obstetrics and Pediatrics in *** patient underwent several ovarian stimulation cycles to accumulate a certain number of oocytes that would be *** the last oocyte retrieval,all patient’s oocytes including both frozen and fresh would be *** outcomes included the rates of oocyte survival,cleavage embryo,blastocyst,ploidy status,pregnancy,biochemical pregnancy and clinical ***:The oocyte survival rate after thawing was 96.5%.No statistically significant difference was found when comparing fresh and frozen oocytes regarding fertilization rate(78.1%vs.75.5%,P=0.461),usable cleavage embryo rate(86.9%vs.87.2%,P=0.916)but usable blastocyst rate was found higher statistically in the frozen oocyte group(44.4%vs.54.0%,P=0.049).The percentages of euploid,aneuploid and mosaic embryos between the fresh group and the vitrified group had no significant differences(33.8%vs.31.6%,P=0.682;51.0%vs.54.2%,P=0.569;15.2%vs.12.4%,P=0.787;respectively).The rates of pregnancy,biochemical pregnancy and clinical pregnancy had no statistical difference(68.8%vs.64.8%,P=0.764;12.5%vs.3.6%,P=0.258;37.5%vs.46.4%,P=0.565).17 Mature oocytes are the minimum to have at least one euploid ***:Oocyte vitrification does not affect embryonic,genetic and clinical *** number of mature oocytes should be considered for fertilization in some cases.

关键词： Clinical outcomes Embryonic development Genetic outcomes Human oocyte Oocyte accumulation Oocyte cryopreservation Ploidy status Vitrified oocyte

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CONVERGENCE RESULTS FOR NON-OVERLAP SCHWARZ WAVEFORM RELAXATION ALGORITHM WITH CHANGING tranSMISSION CONDITIONS

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Acta Mathematica Scientia 2022年第1期42卷 105-126页

作者： Minh-Phuong tran Thanh-Nhan NGUYEN Phuoc-Toan HUYNH Nhu-Binh LY Minh-Dang NGUYEN Quoc-anh HO Applied Analysis Research Group Faculty of Mathematics and StatisticsTon Duc Thang UniversityHo Chi Minh cityVietnam Department of Mathematics Ho Chi Minh City University of EducationHo Chi Minh cityVietnam Faculty of Mathematics and Statistics Ton Duc Thang UniversityHo Chi Minh cityVietnam

In this paper,we establish a new algorithm to the non-overlapping Schwarz domain decomposition methods with changing transmission conditions for solving one dimensional advection reaction diffusion *** precisely,we first describe the new algorithm and prove the convergence results under several natural assumptions on the sequences of parameters which determine the transmission *** we give a simple method to estimate the new value of parameters in each *** interesting advantage of our method is that one may update the better parameters in each iteration to save the computational cost for optimizing the parameters after many *** some numerical experiments are performed to show the behavior of the convergence rate for the new method.

关键词： domain decomposition method Schwarz waveform relaxation algorithm advection reaction diffusion changing transmission conditions

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Conflict management styles of nurse managers and influencing factors in children’s hospital, Vietnam

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Journal of Integrative Nursing 2023年第4期5卷 266-272页

作者： Ha Manh tuan tran Thi Hong HUONG Le Viet TUNG Postgraduate Department University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh CityVietnam Head of Branch 2 University Medical Center Ho Chi Minh CityHo Chi Minh CityVietnam Department of Ophthalmology Children’s Hospital 1Ho Chi Minh CityVietnam Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh CityVietnam Training and Scientific Research Department University Medical Center Ho Chi Minh CityHo Chi Minh CityVietnam

Objective:This study aimed to describe the conflict management styles and identify factors affecting the conflict management styles of nurse *** and Methods:A cross-sectional study was conducted by interviewing nurse managers with a questionnaire,including the Rahim Organizational Conflict Inventory-II Form B,used to assess an individual’s approach to conflict management across five styles:cooperating,competing,compromising,obliging,and ***:A total of 30 nurse managers participated in this *** mean scores of the cooperating style were the highest at 4.3±0.4,followed by a compromising style at 3.4±0.5,an avoiding style at 3.1±0.6,an accommodating style at 2.9±0.7,and a competing style at 2.8±0.8(χ^(2)=66.624,P<0.001).The mean scores for avoiding style among bachelor’s degree nurse managers(3.2±0.6)were higher than those of master’s degree nurse managers(2.7±0.6)(P=0.036).Nurse managers over 40 years old,holding a managerial position for≥10 years,and frequent conflict handling rated higher mean scores for the cooperating style than their counterparts(P<0.05).Conclusion:The cooperating style was the most commonly used conflict management style among nurse *** affecting the conflict management style were age,education level,and experience in management and conflict *** findings are useful for developing interventions that enhance the competencies of nurse managers in conflict management.

关键词： Conflict conflict management nurse nurse manager

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Studies on sustainable features of vernacular architecture in different regions across the world:A comprehensive synthesis and evaluation

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Frontiers of Architectural Research 2019年第4期8卷 535-548页

作者： anh tuan Nguyen Nguyen Song Ha Truong David Rockwood anh Dung tran Le Faculty of Architecture the University of Danang-University of Science and TechnologyDa NangViet Nam School of Architecture University of Hawaii at ManoaUSA Laborotoire des Technologies Innovantes(LTI) Universite de Picardie Jules VerneFrance

Due to the increasing pressure brought by recent global environmental problems,building designers are embracing regionalism and the knowledge of traditional structures,arguing that these structures are energy efficient and highly *** observe clear evidence of the increasing interest in vernacular architecture among the research *** study therefore aims to clarify the contents and issues raised in the studies on vernacular architecture and the knowledge and recommendations that can be derived from them.A database of the research is established by collecting many studies from primary *** data is carefully refined and categorized into a table where synthesized information is *** results of this study show an uneven geographic and climatic distribution of the studies;the trend in selecting research objectives and research objects;the choice of research methods with a clear shift towards quantitative research methods,and the generic findings from the database of the *** results can support diverse inquiries about vernacular architecture across the world and be used as a resource or an orientation to support numerous subsequent studies.

关键词： Vernacular architecture Traditional architecture Sustainable feature Research method Building design

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The future of COVID-19 vaccination rates for children

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Asian Pacific Journal of Tropical Medicine 2022年第9期15卷 381-382页

作者： Giao Huynh Kimberly H.Nguyen Han Thi Ngoc Nguyen tuan Diep tran Pham Le An Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh CityVietnam Department of Public Health and Community Medicine Tufts University School of MedicineBostonMAUSA Infection Control Department University Medical Center Ho Chi Minh CityHo Chi Minh CityVietnam Faculty of Medicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh CityVietnam Family Medicine Training Center University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh CityVietnam

The COVID-19 pandemic has been ongoing for over two years since the first case was reported in the end of January *** has successfully controlled the pandemic through its vaccination campaign,targeted messages and applications of various public health interventions including social distancing,quarantining,masking,and hand washing,which have made some significant achievements in reducing hospitalizations and deaths[1].

关键词： vaccination targeted COV

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