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Anatomic Anteversion of the Acetabular Component Correlates with Polyethylene Linear Wear in Total Hip Arthroplasty: The Three-Dimensional Numerical Analysis

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Open Journal of Orthopedics 2016年第6期6卷 126-134页

作者： Ima Kosukegawa Satoshi Nagoya Mitsunori Kaya Mikito sasaki Shunichiro Okazaki Daisuke Suzuki toshihiko Yamashita Department of Orthopedic Surgery Sapporo Medical University Sapporo Japan Department of Musculoskeletal Biomechanics and Surgical Development Sapporo Medical University Sapporo Japan

Background: Although abduction of the acetabular component is considered to predict factors for polyethylene wear attributable to osteolysis, other radiographic factors have yet to be elucidated. The purpose of the present study was to evaluate whether anteversion or change in implantation angle of the acetabular component influences polyethylene linear wear by using standing and supine radiographs of the hip joint. Methods: Standing and supine plain anteroposterior radiographs of 62 hip joints in which cementless total hip arthroplasty was performed were examined for polyethylene linear wear rate (mm/year), pelvic inclination, and radiological inclination and anatomic anteversion of the acetabular component. Results: All correlation coefficients of measurements of polyethylene linear wear, pelvic inclination angle, anatomical anteversion angle and radiological inclination angle were calculated highly. And by the three-dimensional numerical analysis, anatomic anteversion of the acetabular component had at least some effect on the degree of polyethylene wear. Conclusion: This study suggests that increased anteversion of the acetabular component reduces polyethylene linear wear in metal-on-polyethylene total hiparthroplasty.

关键词： Total Hiparthroplasty Polyethylene Linear Wear Standing Position Settingangle of Acetabular Component

Simultaneous removal of cesium and strontium using a photosynthetic bacterium, <i>Rhodobacter sphaeroides</i>SSI immobilized on porous ceramic made from waste glass

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Advances in Bioscience and Biotechnology 2013年第1期4卷 6-13页

作者： Ken sasaki Hiroyo Morikawa Takashi Kisibe Kenji Takeno Ayaka Mikami toshihiko Harada Masahiro Ohta Materials Science and Engineering Graduate School of Engineering Hiroshima Kokusa Gakuin University Hiroshima Japan Meisui-Bio Research Institute Hiroshima Kokusai Gakuin University Hiroshima Japan Ohta-Kokan Co. Ltd. Hiroshima Japan Relation Creative Office Co. Ltd. Hiroshima Japan

This study investigated practical and simultaneous removal of cesium (Cs, initial concentration of 5 mg/L) and strontium (Sr, initial concentration of 5 mg/L) using a photosynthetic bacterium, Rhodobacter sphaeroides SSI, immobilized on recovery-type porous ceramic made from glass waste. When 4 - 8 pieces /L of SSI immobilized ceramic were added to synthetic sewage wastewater containing glucose, almost 100% of Cs and 57% - 61% removal of Sr was observed after 3 day’s aeration treatment. The high potassium (K) concentration in wastewater suppressed Cs removal, but did not affect Sr removal. Other substrates such as lactic, acetic, and propionic acids were useful for Cs and Sr removal. But, removal efficiencies were lower than about 50%. When the practical outdoor removal experiment carried out using1 m3 vessel, almost 100% of Cs and 51% of Sr were removed like a laboratory experiment after 3 day’s aerobic treatment. After treatment, the SSI immobilized ceramic was recovered easily from water using an electromagnet. This SSI immobilized ceramic seem to remove radioactive Cs and Sr from water environments of Fukushima,Japan.

关键词： Cs and Sr Removal Photosynthetic Bacteria Immobilization Ceramic Made from Waste Glass Recovery Type-Ceramic

5-ALA-mediated photodynamic treatment Induces caspase-dependent and-Independent cell death in human histiocytic lymphoma cell line U937

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5-ALA-mediated photodynamic treatment Induces caspase-depend...

Dosimetric Comparison of Different Prescription Modes in Lung Stereotactic Body Radiation Therapy

21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology

作者： Kozo Utsuml Masataka Uchida Hirofumi Fujita toshihiko Utsumi Keiji Inoue Junzo sasaki Okayama University Graduate School of Medicine DentistryPharmaceutical Sciences Graduate School of Medicine Yamaguchi University Medical School Kochi University

＜正＞The photodynamic treatment（PDT） using 5-aminolevulinic acid（ALA） is one of the new therapeutic modalities for malignant *** mechanism of cell damage induced by ALA-mediated PDT is not fully *** treatment of human histiocytic lymphoma U937 cell line cultures by ALA-based PDT resulted in apoptotic cell death,chromatin condensation,phos-

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2014年第1期3卷 14-19页

作者： Hideharu Miura Norihisa Masai Ryoong-Jin Oh Hiroya Shiomi Kouichi Yamada Junichi sasaki Muhammad Nauman Usmani toshihiko Inoue Department of Medical Physics & Engineering Osaka University Graduate School of Medicine Osaka Japan Miyakojima IGRT Clinic Osaka Japan

The purpose of this study was to compare the dose-volume statistics of stereotactic body radiotherapy (SBRT) for lung cancer between planning target volume (PTV): D95 and gross tumor volume (GTV): D99 dose prescriptions using Monte Carlo (MC) calculation. Plans for 183 patients treated between October 2010 and April 2013 were generated based on four-dimensional (4D) computed tomography (CT) under free breathing. A uniform margin of 8 mm was added to the internal target volume (ITV) to generate PTV. A leaf margin of 2 mm was added to the PTV. The plans were calculated with two different dose prescription methods: 40 Gy to cover 95% of the PTV (PTV prescription) and 44 Gy to cover 99% of the GTV (GTV prescription). A 6-MV photon beam was used. A dose-volume histogram (DVH) analysis was performed for dose to the GTV using PTV and GTV dose prescriptions. For each treatment plan, we evaluated the minimum dose to 99% of the GTV (D99). The D99 of GTV was 44.5 ± 1.9 Gy and 44.0 ± 0.0 Gy for PTV and GTV prescriptions, respectively. The dose to the GTV had wide variations with PTV prescription. We recommend that GTV based dose prescription should be used to standardize dose to the tumor and to achieve highly conformal dose distributions in SBRT for lung cancer.

关键词： Dose Prescription Monte Carlo Calculation Stereotactic Body Radiation Therapy Lung Cancer

Evaluation and Commissioning of Commercial Monte Carlo Dose Algorithm for Air Cavity

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2014年第1期3卷 9-13页

作者： Hideharu Miura Norihisa Masai Kouichi Yamada Junichi sasaki Ryoong-Jin Oh Hiroya Shiomi Muhammad Nauman Usmani toshihiko Inoue Department of Medical Physics & Engineering Osaka University Graduate School of Medicine Osaka Japan Miyakojima IGRT Clinic Osaka Japan

The purpose of this study was to compare the Pencil Beam (PB) with Monte Carlo (MC) calculated dosimetric results using phantoms for air cavity region. Measurements in Tough water phantom with air gaps were used to verify the calculated dose. The plane-parallel ionization chamber was moved from 2 mm to 20 mm behind air gap. Calculations were performed for various air gaps (1.0, 2.0, 3.0 and 4.0 cm) and field sizes (4.2 × 4.2, 6.0 × 6.0 and 9.8 × 9.8 cm2). The lateral missing tissue measurement was performed using the radiochromic RT-QA film. Dose difference between PB and chamber measurement near an air gap was greater for smaller field size, larger air gap thickness, and shallower depth behind air gap. As the distance from the phantom edge became shorter, the dose differences of the PB calculation and film measurement became larger. MC calculations were found within 3% agreement to the measured dose distributions. Our results demonstrate an excellent agreement between ionization chamber and radiochromic RT-QA film measurements and MC calculations.

关键词： Monte Carlo Pencil Beam Air Cavity Treatment Planning