检索结果-南通市图书馆

Nano Research 2021年第2期14卷 512-517页

作者： Gaurav Verma Sanjay Kumar Harsh Vardhan Junyu Ren Zheng Niu tony Pham Lukasz Wojtas Sydney Butikofer Jose C Echeverria Garcia Yu-Sheng Chen Brian Space and Shengqian ma Department of Chemistry University of South Florida4202 E.Fowler Ave.TampaFL 33637USA ChemmatCARS Center for Advanced Radiation SourcesThe University of Chicago9700 South Cass AvenueArgonneIL 60439USA Department of Chemistry Multani Mai Modi CollegePatiala 147001India Department of Chemistry Biochemistryand PhysicsThe University of Tampa401 W.Kennedy Blvd.TampaFL 33606-1490USA Department of Chemical and Biomolecular Engineering University of Illinois at Urbana-ChampaignChampaignIL 61801USA

Emerging as an outperformed class of metal-organic frameworks(mOFs),square-octahedron(soc)topology mOFs(soc-mOFs)feature superior properties of high porosity,large gas storage capacity,and excellent thermal/chemical *** report here an iron based soc-mOF,denoted as Fe-pbpta(H4pbpta=4,4',4'',4'''-(1,4-phenylenbis(pyridine-4,2-6-triyl))-tetrabenzoic acid)possessing a very high Brunauer,Emmett and Teller(BET)surface area of 4,937 m2/g and a large pore volume of 2.15 cm3/*** mOF demonstrates by far the highest gravimetric uptake of 369 cm3(STP)/g under the DOE operational storage conditions(35 bar and 298 K)and a high volumetric deliverable capacity of 192 cc/cc at 298 K and 65 ***,Fe-pbpta exhibits high thermal and aqueous stability making it a promising candidate for on-board methane storage.

关键词： metal-organic framework(mOF) reticular chemistry methane storage aqueous stability high gravimetric and volumetric uptake

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

农业机器的模糊逻辑控制导航

农业机械学报 2000年第3期31卷 31-34页

作者：应火冬 HagrasH callaghan V Colley m Carr-West A 中国水稻研究所农业工程室杭州市310006 ComputerScienceDepartment EssexUniversity ComputerScienceDepartment iculturalEngineeringDepartment WrittleAgriculturalCollege

介绍了一台试验车控制系统的构造 ,设计了一个以实现收获机械自动引导行走为目标的模糊逻辑控制器。试验表明 ,这一控制器具有抗来自断续、不匀称引导基准的噪声干扰的能力。

关键词：模糊逻辑控制自动引导行走农业机械

manufacturing Ultra High Performance Concretes by Silica Fume, Ultra Fine Fly Ash and metakaolin Addition

在线全文

学校读者我要写书评

暂无评论

材料科学与工程（中英文A版） 2017年第3期7卷 136-142页

作者： tony Song Ion Dumitru Bob Bomstein Boral Construction materials Australia

Spectrum of NSD1 gene mutations in southern Chinese patients with Sotos syndrome

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese medical Journal 2005年第18期118卷 1499-1506页

作者： tony m.F. Tong Edgar W.L. Hau Ivan F.m. Lo Daniel H.C. Chan Stephen T.S. Lam Clinical Genetic Service Department of Health Hong Kong SAR China Clinical Genetic Service Department of Health Hong Kong SAR China Clinical Genetic Service Department of Health Hong Kong SAR China Clinical Genetic Service Department of Health Hong Kong SAR China Clinical Genetic Service Department of Health Hong Kong SAR China

Background Sotos syndrome is an overgrowth syndrome with characteristic facial gestalt and mental retardation of variable severity. Haploinsufficiency of the NSD 1 gene has been implicated as the major cause of Sotos syndrome, with a predominance of microdeletions reported in Japanese patients. This study was conducted to investigate into the spectrum of NSD1 gene mutations in southern Chinese patients with Sotos syndrome. methods Thirty-six Chinese patients with Sotos syndrome and two patients with Weaver syndrome were subject to molecular testing. Results NSD1 gene mutations were detected in 26 （72%） Sotos patients. microdeletion was found in only 3 patients, while the other 23 had point mutations （6 frameshift, 8 nonsense, 2 spice site, and 7 missense）. Of these, 19 mutations were never reported. NSD1 gene mutations were not found in the two patients with Weaver syndrome. Conclusions most cases of Sotos syndrome are caused by NSD1 gene defects, but the spectrum of mutations is different from that of Japanese patients. Genotype-phenotype correlation showed that patients with microdeletions might be more prone to congenital heart disease but less likely to have somatic overgrowth. The two patients with Weaver syndrome were not found to have NSD1 gene mutations, but the number was too small for any conclusion to be drawn.

关键词： Sotos syndrome·Weaver syndrome·NSD1 gene mutation

Electrical Homo-Junction Delineation Techniques: A Comparative Study

在线全文

学校读者我要写书评

暂无评论

materials Sciences and Applications 2016年第6期7卷 326-347页

作者： Nicolas Vivet mélanie Diogo Amandine Aubert tony moinet Fabien Allanic Raphael Perdreau Jean-Paul Rebrassé Failure and Technology Analysis Laboratory (LAT) ST Microelectronics Tours France

In active semiconductor devices, the junction characteristics are critical for the electrical performance. As an alternative of the atomic force microscopy (AFm)-based electrical techniques which provide unique junction characterization, other methods are dedicated for the delineation of the electrical junction such as the wet chemical etching, the electrochemical plating method, the Seebeck effect imaging (SEI) method, the electron-beam induced current (EBIC) technique and the secondary electron potential contrast (SEPC) method. The aim of this paper is in the one hand to compare these five techniques in term of sample preparation, spatial application range, spatial resolution, simplicity and information displayed. In the other hand, this review aims to provide some guidelines for the appropriate delineation method(s) selection. It was confirmed that chemical based techniques are the simplest junction delineation methods but exhibit some drawbacks in term of spatial resolution and reproducibility. Despite of a limited spatial resolution, it was evidenced that EBIC can provide accurate electrical characterization of the junction. Finally, it was demonstrated that SEPC is the most promising technique providing the higher spatial resolution. The effect of the sample preparation method has been described. Even if the comparison was mainly based on homo-micro-Silicon junctions (n-p and n-p-n-p), the results were also discussed for short SiC junctions. The importance of the analysis context was considered in this paper and analysis flow was suggested for specific analysis cases.

关键词： Junction Delineation Silicon Silicon Carbide Electron Beam Induced Current Seebeck Effect Imaging Secondary Electron Potential Contrast

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

RImAC C_TWO

汽车测试报告 2018年第6期 76-77页

作者： OLLIE KEW JOHN WYCHERLEY(图) tony(译)

布加迪、科尼赛克和特斯拉请注意，Rimac第二号特级超跑的性能数据间直惊天动地。Rimac声称C_Two身上四台电动机合共可以产生1407kW和2299N-m，左右前轮各有一个单速变速器，加上两个坐镇大后方的双速变速器，极速据称达N415km／h。

关键词：轿车车型品牌安全性能

Apple dwarfing rootstocks exhibit an imbalance in carbohydrate allocation and reduced cell growth and metabolism

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Horticulture Research 2017年第1期4卷 311-323页

作者： Toshi m Foster Peter A mcAtee Chethi N Waite Helen L Boldingh tony K mcGhie The New Zealand Institute for Plant and Food Research Limited Palmerston North4474New Zealand The New Zealand Institute for Plant and Food Research Limited Auckland1142New Zealand The New Zealand Institute for Plant and Food Research Limited Hamilton3240New Zealand

Apple dwarfing rootstocks cause earlier shoot termination and reduced root and shoot *** identify physiological factors responsible for rootstock-induced growth restriction,we compared vascular-enriched gene expression between two dwarfing rootstocks(‘m27’and‘m9’)and the vigorous rootstock‘m793’using RNA sequencing and quantitative reverse transcriptase *** expressed genes common to both dwarfing rootstocks belonged to five main biological processes:(1)primary metabolism,(2)cell wall synthesis and modification,(3)secondary metabolism,(4)hormone signalling and response and(5)redox *** promoting the biosynthesis of amino acids,lipids and cell walls were downregulated in dwarfing rootstocks,whereas genes promoting the breakdown of these compounds were *** only exception to this trend was the upregulation of starch synthesis genes in dwarfing ***-structural carbohydrate analysis demonstrated that starch concentrations in‘m9’roots,stems and grafted‘Royal Gala’(‘RG’)scions were double that of equivalent tissues from‘RG’homo-grafted trees(‘RG’/‘RG’).Fructose and glucose concentrations were much lower in all three tissues of the‘RG’/‘m9’***,these data indicate that dwarfing rootstocks are in a state of sugar depletion and reduced cellular activity despite having large starch *** significant finding was the over-accumulation of flavonoids and the downregulation of auxin influx transporters mdAUX1 and mdLAX2 in dwarfing *** propose that both factors reduce polar auxin *** results of this study contribute novel information about the physiological state of dwarfing rootstocks.

关键词： walls roots dwarf

Prader-Willi Syndrome:16-Year Experience in Hong Kong

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Genetics and Genomics 2012年第4期39卷 191-194页

作者： Ivan F.m. Lo Ho ming Luk luksite@*** tony m.F. Tong Kent K.S. Lai Daniel H.C. Chan Albert C.F. Lam David K.H. Chan Edgar W.L. Hau Connie O.Y. Fung Stephen T.S. Lam Clin Genet Serv Dept Hlth Kowloon Hong Kong Peoples R China

Prader-Willi syndrome （PWS） is an important, well-recognized syndromic form of neurodevelopmental disorder. The incidence is about 1 in 15,000-25,000 live births, and it affects both males and females （Vogels et al... 详细信息

关键词： PWS Prader-Willi Syndrome

Nrf2-mediated antioxidant and detoxifying enzyme induction by a combination of curcumin and sulforaphane

在线全文

学校读者我要写书评

暂无评论

Journal of Chinese Pharmaceutical Sciences 2016年第8期25卷 559-569页

作者： Francisco Fuentes Yury Gomez Ximena Paredes-Gonzalez Avantika Barve Sujit Nair Siwang Yu Constance Lay Lay Saw Ah-Ng tony Kong Facultad de Agronomia e Ingenieria Forestal Pontificia Universidad Cato1ica de Chile Casilla 306-22 Santiago Chile Department of Pharmaceutics Ernest Mario School of Pharmacy Rutgers The State University of New Jersey New Jersey 08854 USA Novartis Institutes for Biomedical Research East Hanover NJ-07470 USA Amrita Cancer Discovery Biology Laboratory Amrita Vishwa Vidyapeetham University Amritapuri Clappana P.O. Kollam Kerala-690525 India School of Pharmaceutical Sciences Peking University Health Science Center Beo'ing 100191 China

The dietary phytochemicals curcumin （CUR） and sulforaphane （SFN） have shown remarkable cancer chemopreventive effects in many model systems. This study was designed to investigate the induction of Nrf2-mediated antioxidant enzymes by combining doses of CUR and SFN and the effect of their combination on the Nrf2-ARE （antioxidant response element） response in HepG2-C8 cells. We hypothesized that the combination of the polyphenol CUR and the isothiocyanate SFN could enhance the induction of AREs and Nrf2-target enzymes. HepG2-C8 cells were treated with a combination of low doses of CUR, SFN or both. The induction of Nrf2-mediated antioxidant and phase II detoxifying enzymes-heme oxygenase-1 （HO-I） and UDP-glucuronosyltransferase-1A （UGT1A）-was measured by real-time RT-PCR and western blotting. ARE-luciferase activity was also quantified. Low doses of CUR （10 ~tm） and SFN （12.5 ~tm） significantly induced the expression of HO-1 and UGT 1 A1 proteins. Through the use of chemical inhibitors of mRNA and protein synthesis, the combination of CUR and SFN was shown to affect the transcriptional regulation of both HO-1 and UGT1A1. Additionally, the combination of CUR and SFN synergistically induced the expression of Nrf2- and ARE-luciferase activity in HepG2-C8 cells. Thus, CUR and SFN at low concentrations augment therapeutic effects in HepG2-C8 cells. The enhanced ARE-luciferase activity of combined CUR and SFN treatment could partly explain the significant induction of the Nrf2-target enzymes HO-1 and UGT1A1. Taken together, our results suggest that combining low doses of CUR and SNF could be a promising strategy for cancer chemoprevention in humans.

关键词： Antioxidant response element, Curcumin, HepG2-C8 cell-s, HO-1, Nrf2, Sulforaphane, UGT 1A1

大脑血管内胆碱乙酰转移酶免疫反应活性(英文)

在线全文

学校读者我要写书评

暂无评论

中国药理学与毒理学杂志 1992年第1期6卷 28-35页

作者： Jun-Ge YU Jang-Yen WU tony J-F LEE Department of Pharmacology Southern Illinois University School of Medicine Springfield Illinois 62794-19230 USADepartment of Pharmacology Southern Illinois University School of Medicine Springfield Illinois 62794-19230 USADepartment of Pharmacology Southern Illinois University School of Medicine Springfield Illinois 62794-19230 USA

本文采用间接免疫荧光染色(双抗体法)和非标记抗体-过氧化物酶-抗过氧化物酶法(PAP法),使用抗纯化胆碱乙酰转移酶(CHAT)抗体,对猫和猪各种体积的脑软膜动静脉,脑实质内微血管以及脉络丛的乙酰胆碱能神经的存在和分布进行了研究。结果表... 详细信息

本文采用间接免疫荧光染色(双抗体法)和非标记抗体-过氧化物酶-抗过氧化物酶法(PAP法),使用抗纯化胆碱乙酰转移酶(CHAT)抗体,对猫和猪各种体积的脑软膜动静脉,脑实质内微血管以及脉络丛的乙酰胆碱能神经的存在和分布进行了研究。结果表明,脑软膜动静脉的ChAT免疫反应性神经主要是成束状的,只有少数是由细小纤维组成,静脉的此类神经供应少于其动脉供应程度,同时,ChAT免疫反应纤维的密度又与血管的体积成比例,在小分枝的动静脉上(外径小于30μm)通常观察不到此类纤维的存在,脉络丛的动静脉有ChAT免疫反应性神经存在,但此类神经在实质内微血管则观察不到,以上结果与以前报告过的颅内和实质外动脉的乙酰胆碱酯酶(AChE)性纤维的密度比同类静脉所存在密度大的结果相符,而ChAT免疫反应纤维分布的方式则与报告过的AChE性纤维的分布方式不同,后者主要是由细小纤维组成,尽管离体的实质内微血管无ChAT免疫反应纤维,但胆碱能神经接近和“突触化”此类微血管的可能性不能排除,脑软膜血管一些内皮细胞胞浆内也有ChAT免疫反应活性存在,因此,本文结果与神经元和血管内皮两者的胆碱能机构在控制脑循环中起着重要作用之假说相一致。

关键词：胆碱乙酰转移酶胆碱能神经支配