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新生儿PICC相关性血栓预防与管理的证据总结

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中国护理管理 2024年第3期24卷 418-424页

作者：方运霞刘佳惠林琴彭思意魏涛袁忠王童语李旭英湖南中医药大学护理学院长沙市410208 湖南省肿瘤医院乳腺内科湖南省肿瘤医院血管通道中心湖南省肿瘤医院早期临床中心湖南省肿瘤医院麻醉科湖南省肿瘤医院护理部

目的:总结新生儿经外周静脉置入中心静脉导管(PICC)相关性血栓预防与管理的证据,为临床医护人员提供循证依据。方法:系统检索国内外临床决策网站、指南网站、专业协会网站、循证文献资源库及原始文献数据库,检索时限为建库至2023年2月... 详细信息

目的:总结新生儿经外周静脉置入中心静脉导管(PICC)相关性血栓预防与管理的证据,为临床医护人员提供循证依据。方法:系统检索国内外临床决策网站、指南网站、专业协会网站、循证文献资源库及原始文献数据库,检索时限为建库至2023年2月。对纳入的文献进行方法学质量评价,结合专业判断、临床情境提取证据并进行汇总。结果:共纳入14篇文献,其中临床决策2篇,指南6篇,系统评价4篇,队列研究2篇。从风险评估、导管置入、导管维护、血栓诊断、血栓治疗、拔管等6个方面共汇总了31条证据。结论:本研究总结了新生儿PICC相关性血栓预防及管理的证据。医护人员可结合文化背景、临床情境选择证据,制定科学的血栓预防及管理方案,提升护理质量。

关键词：导管相关性血栓经外周静脉置入中心静脉导管新生儿证据总结

ROS-removing nano-medicine for navigating inflammatory microenvironment to enhance anti-epileptic therapy

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Acta Pharmaceutica Sinica B 2023年第3期13卷 1246-1261页

作者： Zheng Zhou Keying Li Yongchao Chu Chao Li tongyu Zhang Peixin liu Tao Sun Chen Jiang Department of Pharmaceutics School of PharmacyFudan University、Key Laboratory of Smart Drug DeliveryMinistry of Education、State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain ScienceShanghai 201203China

As a neurological disorder in the brain,epilepsy is not only associated with abnormal synchronized discharging of neurons,but also inseparable from non-neuronal elements in the altered ***-epileptic drugs(AEDs)merely focusing on neuronal circuits frequently turn out deficient,which is necessitating comprehensive strategies of medications to cover over-exciting neurons,activated glial cells,oxidative stress and chronic inflammation ***,we would report the design of a polymeric micelle drug delivery system that was functioned with brain targeting and cerebral microenvironment *** brief,reactive oxygen species(ROS)-sensitive phenylboronic ester was conjugated with poly-ethylene glycol(PEG)to form amphiphilic ***,dehydroascorbic acid(DHAA),an analogue of glucose,was applied to target glucose transporter 1(GLUT1)and facilitate micelle penetration across the blood‒brain barrier(BBB).A classic hydrophobic AED,lamotrigine(LTG),was encapsulated in the micelles via *** administrated and transferred across the BBB,ROS-scavenging polymers were expected to integrate anti-oxidation,anti-inflammation and neuro-electric modulation into one ***,micelles would alter LTG distribution in vivo with improved ***,the combined anti-epileptic therapy might provide effective opinions on how to maximize neuroprotection during early epileptogenesis.

关键词： Epilepsy Polymeric micelle Reactive oxygen species Inflammation Gliosis Neuroprotection

基于OBE理念的单片机原理及接口技术线上线下混合式教学模式实践

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农业科技与装备 2024年第2期 134-136,140页

作者：于丰华李征明姚萍刘潭许童羽沈阳农业大学信息与电气工程学院沈阳110161

以满足工程教育认证标准中对单片机原理及接口技术课程的需求为出发点,分析传统单片机教学模式中存在的问题。基于OBE理念对传统教学模式进行重构,通过引入项目案例、SPOC资源、口袋实验室等来构建基于OBE理念的单片机原理及接口技术线... 详细信息

以满足工程教育认证标准中对单片机原理及接口技术课程的需求为出发点,分析传统单片机教学模式中存在的问题。基于OBE理念对传统教学模式进行重构,通过引入项目案例、SPOC资源、口袋实验室等来构建基于OBE理念的单片机原理及接口技术线上线下混合式教学模式,以此来提升学生的主体地位、加强学生自学能力的培养、探索更加适合农业院校电子信息类专业学生特点的教学方法、提升学生解决工程实际问题的能力。

关键词： OBE 线上线下混合式教学单片机课程改革

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自动驾驶安全关键场景生成技术综述

信息与控制 2024年第1期53卷 17-32,46页

作者：王淳浩闭家铭阮利魏彤羽任宇翔黄镇刘云韬纪岳天思 SAW Yinxuan 肖利民北京警察学院北京市公安局智能网联汽车交通事故调查与重建标准实验室北京102202 北京航空航天大学复杂关键软件环境国家重点实验室北京100191 证据科学教育部重点实验室(中国政法大学) 北京100088 北京航空航天大学计算机学院北京100191

安全关键场景生成是自动驾驶的重要方向,在自动驾驶测试、汽车安全性评估和汽车安全标准构建等领域都有着很高的应用价值,是关系自动驾驶应用落地的关键。现有研究缺乏重点围绕安全关键场景生成技术的综述,因此本文对安全关键场景生成... 详细信息

安全关键场景生成是自动驾驶的重要方向,在自动驾驶测试、汽车安全性评估和汽车安全标准构建等领域都有着很高的应用价值,是关系自动驾驶应用落地的关键。现有研究缺乏重点围绕安全关键场景生成技术的综述,因此本文对安全关键场景生成技术进行了系统性综述。首先,分析了安全关键场景生成技术的综述相关研究;其次,对安全关键场景生成模型进行了对比分析;再次,分类总结了基于聚类、贝叶斯网络和对抗网络的安全关键场景生成方法的进展;最后,对安全关键场景生成方法研究趋势进行了展望。

关键词：自动驾驶汽车安全关键场景场景生成深度生成模型

Downwash airflow field distribution characteristics and their effect on the spray field distribution of the DJI T30 six-rotor plant protection UAV

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International Journal of Agricultural and Biological Engineering 2023年第2期16卷 10-22页

作者： Haiyan Zhang Sheng Wen Chunling Chen Qi liu tongyu Xu Shengde Chen Yubin Lan College of Information and Electrical Engineering Shenyang Agricultural UniversityShenyang 110866China College of Engineering South China Agricultural UniversityGuangzhou 510642China College of Agricultural Engineering and Food Science Shandong University of TechnologyZibo 255022ShandongChina College of Electronic Engineering(College of Artificial Intelligence) South China Agricultural UniversityGuangzhou 510642China National Center for International Collaboration Research on Precision Agricultural Aviation Pesticides Spraying Technology Guangzhou 510642China

Spray characteristics are the fundamental factors that affect droplet transportation downward,deposition,and *** downwash airflow field of the Unmanned Aviation Vehicle(UAV)primarily influences droplet deposition and drift by changing the spray *** study focused mainly on the effect of the downwash airflow field of the UAV and nozzle position on the droplet spatial distribution and velocity distribution,which are two factors of spray *** study the abovementioned characteristics,computational fluid dynamics based on the lattice Boltzmann method(LBM)was used to simulate the downwash airflow field of the DJI T30 six-rotor plant protection UAV at different rotor rotational speeds(1000-1800 r/min).A particle image velocimetry system(PIV)was utilized to record the spray field with the downwash airflow field at different rotational speeds of rotors(0-1800 r/min)or different nozzle positions(0,0.20 m,0.35 m,and 0.50 m from the motor).The simulation and experimental results showed that the rotor downwash airflow field exhibited the‘dispersion-shrinkage-redispersion’development *** the initial dispersion stage of rotor airflow,there were obvious high-vorticity and low-vorticity regions in the rotor downwash airflow ***,the low-vorticity region was primarily concentrated below the motor,and the high-vorticity region was mainly focused in the middle area of the ***,the Y-direction airflow velocity fluctuated at 0.4-1.2 m under the *** the rotor airflow developed to 3.2 m below the rotor,the Y-direction airflow velocity showed a slight *** 3.2 m from the rotor,the Y-direction airflow velocity started to drastically ***,it is recommended that the DJI T30 plant protection UAV should not exceed 3.2 m in flight height during field spraying *** rotor downwash airflow field caused the nozzle atomization angle,droplet concentration,and spray field width to decrease while inc

关键词： downwash airflow spray field distribution plant protection UAV characteristics

Ridge subduction, magmatism, and metallogenesis

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Science China Earth Sciences 2020年第10期63卷 1499-1518页

作者： Qiang WANG Gongjian TANG Lulu HAO Derek WYMAN Lin MA Wei DAN Xiuzheng ZHANG Jinheng liu tongyu HUANG Chuanbing XU State Key Laboratory of Isotope Geochemistry Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou 510640China CAS Center for Excellence in Tibetan Plateau Earth Sciences Beijing 100101China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China School of Geosciences The University of SydneyNSW 2006Australia

Modern oceans contain large bathymetric highs(spreading oceanic ridges,aseismic ridges or oceanic plateaus and inactive arc ridges)that,in total,constitute more than 20–30%of the total area of the world’s ocean *** bathymetric highs may be subducted,and such processes are commonly referred to as ridge *** ridge subduction events are not only very common and important geodynamic processes in modern oceanic plate tectonics,they also play an important role in the generation of arc magmatism,material recycling,the growth and evolution of continental crust,the deformation and modification of the overlying plates,and metallogenesis at convergent plate ***,these events have attracted widespread *** perpendicular or high-angle subduction of mid-ocean spreading ridges is commonly characterized by the occurrence of a slab window,and the formation of a distinctive adakite–high-Mg andesite–Nb-enriched basalt-oceanic island basalt(OIB)or a mid-oceanic ridge basalt(MORB)-type rock suite,and is closely associated with Au *** ridges or oceanic plateaus are traditionally considered to be difficult to subduct,to typically collide with arcs or continents or to induce flat subduction(low angle of less than 10°)due to the thickness of their underlying normal oceanic crust(>6–7 km)and high ***,the subduction of aseismic ridges and oceanic plateaus occurred on both the western and eastern sides of the Pacific Ocean during the *** the eastern side of the Pacific Ocean,aseismic ridges or oceanic plateaus are being subducted flatly or at low angles beneath South and Central American continents,which may cause a magmatic *** slab melting can occur and adakites,or an adakite–high-Mg andesite–adakitic andesite–Nb-enriched basalt suite may be formed during the slab rollback or ***-Au mineralization is commonly associated with such flat subduction *** the western side of the Pacific Ocean,ho

关键词： Spreading mid ocean ridge Aseismic ridge Oceanic plateau Inactive arc ridge Subduction Magmatism Metal minerlization Crustal growth

Enhanced charge separation by continuous homojunction with spatially separated redox sites for hydrogen evolution

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Nano Research 2023年第10期16卷 12323-12330页

作者： Mingyuan Yu tongyu Wang Chengxi Huang Fang Wu Xuan liu Hailing Huo Hanwen Jian Zikun Liang Jingjing Ma Erjun Kan Ang Li MIIT Key Laboratory of Semiconductor Microstructure and Quantum Sensing School of ScienceNanjing University of Science and TechnologyNanjing 210094China College of Information Science and Technology Nanjing Forestry UniversityNanjing 210037China State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering Ningxia UniversityYinchuan 750021China

Photocatalytic hydrogen generation represents a promising strategy for the establishment of a sustainable and environmentally friendly energy ***,the current solar-to-hydrogen conversion efficiency is not yet sufficient for practical hydrogen production,highlighting the need for further research and ***,we report the synthesis of a Sn-doped TiO_(2)continuous homojunction hollow sphere,achieved through controlled calcination *** incorporation of a gradient doping profile has been demonstrated to generate a gradient in the band edge energy,facilitating carrier orientation ***,the hollow sphere’s outer and inner sides provide spatially separated reaction sites allowing for the separate acceptance of holes and electrons,which enables the rapid utilization of carriers after *** a result,the hollow sphere TiO_(2)with gradient Sn doping exhibits a significantly increased hydrogen production rate of 20.1 mmol·g^(−1)·h^(−1).This study offers a compelling and effective approach to the designing and fabricating highly efficient nanostructured photocatalysts for solar energy conversion applications.

关键词： continuous homojunction spatially separated reaction sites charge separation hydrogen evolution

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车古201潜山油藏完井方式研究

石油钻探技术 2002年第4期30卷 57-59页

作者：杨同玉刘新华金潮苏胜利油田有限公司采油工艺研究院山东东营257062 胜利石油管理局钻井工艺研究院山东东营257017 胜利石油管理局孤岛采油厂山东东营257237

研究了国内外潜山油藏完井方式应用及其使用条件、井身结构的应用 ,针对车古 2 0 1油藏特点 ,论证了其对裸眼完井、筛管完井、尾管射孔完井、管外封隔器完井的适应性 ,通过对比研究 ,从更好地满足油藏工程、采油工艺、增产措施出发 ,选... 详细信息

研究了国内外潜山油藏完井方式应用及其使用条件、井身结构的应用 ,针对车古 2 0 1油藏特点 ,论证了其对裸眼完井、筛管完井、尾管射孔完井、管外封隔器完井的适应性 ,通过对比研究 ,从更好地满足油藏工程、采油工艺、增产措施出发 ,选择出车古 2 0 1潜山油藏最合理的完井方式为尾管注水泥射孔完井。

关键词：完井方式古潜山油藏井身结构裸眼完井射孔完井衬管完井

CsPbBr_(3)-DMSO merged perovskite micro-bricks for efficient X-ray detection

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Nano Research 2023年第7期16卷 9983-9989页

作者： tongyu Shi Wenjun liu Jiongtao Zhu Xiongsheng Fan Zhengyu Zhang Xingchen He Rui He Jiahong Wang Kezhen Chen Yongshuai Ge Xiangming Sun Yanliang liu Paul K.Chu Xue-Feng Yu Shenzhen Institute of Advanced Technology Chinese Academy of SciencesShenzhen 518055China University of Chinese Academy of Sciences Beijing 100049China Nano Science and Technology Institute University of Science and Technology of ChinaSuzhou 215123China Key Laboratory of Quark and Lepton Physics(MOE) Central China Normal UniversityWuhan 430079China Department of Physics Department of Materials Science and Engineeringand Department of Biomedical EngineeringCity University of Hong KongHong Kong 999077China

Inorganic perovskite wafers with good stability and adjustable sizes are promising in X-ray detection but the high synthetic temperature is a ***,dimethyl sulfoxide(DMSO)is used to prepare the CsPbBr_(3)micro-bricks powder at room *** CsPbBr_(3)powder has a cubic shape with few crystal defects,small charge trap density,and high crystallinity.A trace amount of DMSO attaches to the surface of the CsPbBr_(3)micro-bricks via Pb-O bonding,forming the CsPbBr_(3)-DMSO *** hot isostatic processing,the released DMSO vapor merges the CsPbBr_(3)micro-bricks,producing a compact and dense CsPbBr_(3)wafer with minimized grain boundaries and excellent charge transport *** CsPbBr_(3)wafer shows a large mobility-lifetime(μτ)product of 5.16×10^(-4)cm^(2)·V^(-1),high sensitivity of 14,430μC·Gyair^(-1)·cm^(-2),low detection limit of 564 nGyair·s^(-1),as well as robust stability in X-ray *** results reveal a novel strategy with immense practical potential pertaining to high-contrast X-ray detection.

关键词： CsPbBr_(3)-DMSO inorganic perovskites wafer grain growth crystal defect X-ray detector