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Evaluating microvascular invasion in hepatitis B virus-related hepatocellular carcinoma based on contrast-enhanced computed tomography radiomics and clinicoradiological factors

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World Journal of Gastroenterology 2024年第45期30卷 4801-4816页

作者： Zi-Ling Xu Gui-Xiang Qian Yong-Hai Li Jian-Lin Lu Ming-tong wei Xiang-Yi Bu Yong-Sheng Ge Yuan Cheng wei-Dong Jia Department of General Surgery Anhui Provincial Hospital Affiliated to Anhui Medical UniversityHefei 230001Anhui ProvinceChina Department of General Surgery Anhui Provincial HospitalThe First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Science and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Anorectal Surgery The First People's Hospital of HefeiHefei 230001Anhui ProvinceChina

BACKGROUND Microvascular invasion(MVI)is a significant indicator of the aggressive behavior of hepatocellular carcinoma(HCC).Expanding the surgical resection margin and performing anatomical liver resection may improve outcomes in patients with ***,no reliable preoperative method currently exists to predict MVI status or to identify patients at high-risk group(M2).AIM To develop and validate models based on contrast-enhanced computed tomo-graphy(CECT)radiomics and clinicoradiological factors to predict MVI and identify M2 among patients with hepatitis B virus-related HCC(HBV-HCC).The ultimate goal of the study was to guide surgical *** A total of 270 patients who underwent surgical resection were retrospectively *** cohort was divided into a training dataset(189 patients)and a validation dataset(81)with a 7:3 *** features were selected using intra-class correlation coefficient analysis,Pearson or Spearman’s correlation analysis,and the least absolute shrinkage and selection operator algorithm,leading to the construction of radscores from CECT *** and multivariate analyses identified significant clinicoradiological factors and radscores associated with MVI and M2,which were subsequently incorporated into predictive *** models’performance was evaluated using calibration,discrimination,and clinical utility *** Independent risk factors for MVI included non-smooth tumor margins,absence of a peritumoral hypointensity ring,and a high radscore based on delayed-phase CECT *** MVI prediction model incorporating these factors achieved an area under the curve(AUC)of 0.841 in the training dataset and 0.768 in the validation *** M2 prediction model,which integrated the radscore from the 5 mm peritumoral area in the CECT arterial phase,α-fetoprotein level,enhancing capsule,and aspartate aminotransferase level achieved an AUC of 0.865 in the training dataset and 0.798 in the validation

关键词： Radiomics Contrast-enhanced computed tomography Hepatocellular carcinoma Microvascular invasion Hepatitis B virus

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In situ rapid versatile method for the preparation of zirconium metal-organic framework filters

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Science China Chemistry 2022年第12期65卷 2462-2467页

作者： Hang Wang Xingmao Zhang Ruxin Yao Shuang Zhao Pengfei Zhao Ruile Yang Lin Wang Yichao Huang tong wei Xiang Li Zhuangjun Fan Bo Wang School of Materials Science and Engineering China University of PetroleumQingdao266580China Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials Key Laboratory of Cluster ScienceMinistry of EducationSchool of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing100081China Key Laboratory of Magnetic Molecules&Magnetic Information Materials(Ministry of Education) Institute of Chemistry and CultureSchool of Chemistry&Material ScienceShanxi Normal UniversityTaiyuan030006China

The development of the rapid preparation of highly stable metal-organic framework(MOF)-based devices provides the possibility of meeting the increasing demands of MOF in industrial ***,MOFs experience poor processability and stable high-valence-metal(Ⅳ)-based MOFs favor forming either thermodynamically stable metal hydroxides or oxides during their growth and nucleation,which hinders their practical ***,we present a versatile deep eutectic solvent(DES)-assisted hot pressing method to in situ rapidly prepare six distinct zirconium-based MOF nanocrystals on fibers(denoted as Zr-MOFilters)within 20 min.A small amount of DES promotes MOF precursor contact and accelerates Zr-MOF *** and pressure facilitate the formation of Zr-MOFs onto desired *** situ1H nuclear magnetic resonance spectra and time-dependent Fourier-transform infrared spectra were conducted to elucidate the growth of Zr-MOF *** a proof-of-concept,the abilities of Zr-MOFilters for Cr_(2)O_(7)^(2−) and micro(nano)plastics removal have been *** strategy paves the way for the rapid fabrication of highly stable MOF-based devices and brings MOFs a step closer to practical application.

关键词： in situ UiO-66 DES hot pressing filter pollutant control

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100 kA/10kV thyristor stack design for the quench protection system in CRAFT

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Plasma Science and Technology 2023年第5期25卷 193-206页

作者：仝玮徐猛李华陈波宋执权 School of Electrical Engineering and Automation Hefei University of TechnologyHefei 230009People’s Republic of China Institute of Plasma Physics Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031People’s Republic of China University of Science and Technology of China Hefei 230026People’s Republic of China

Thyristors have longer lifetimes,higher reliability,and very high voltage and current ratings and they require less maintenance than other high-power semiconductor *** a result,they are particularly suitable for quench protection systems(QPSs),which protect the superconducting magnets in large fusion devices from *** this paper,we propose a design for a 100 k A/10 k V thyristor stack supported by both theoretical and simulation-based analyses as well as experimental *** to the ultrahigh electrical performance requirements imposed on the QPS by the Comprehensive Research Facility for Fusion Technology(CRAFT),three main issues must be considered:the voltage-balancing problem caused by multiple thyristors in a series structure,the increased junction temperature problem caused by extremely high currents,and the reverse recovery phenomenon that arises from the thyristor’s physical ***,a series of detailed theoretical analyses,simulations,and experiments,including a thyristor junction temperature prediction method and reverse recovery process modeling,were carried out to optimize the ***,the reliability and stability of the thyristor stack were verified by a series of prototype *** results confirmed the correctness and accuracy of the proposed thyristor stack design method and also indicated that the proposed thyristor stack can meet the application conditions of a 100 k A QPS in the CRAFT project.

关键词： superconducting magnet thyristor pulsed power supply quench protection system

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A New Ge/F−Co-doped SMF with Enhanced SBS Threshold Fabricated by PCVD

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Chinese Physics Letters 2011年第10期28卷 116-118页

作者： LIU Tian tong wei-Jun ZHANG Fang-Hai ZHANG Xin-Ben DAI Neng-Li LI Jin-Yan Wuhan National Laboratory of Optoelectronics Huazhong University of Science and TechnologyWuhan 430074 State Key Laboratory Yangtze Optical Fiber and Cable Company Ltd.Wuhan 430074

A new single-mode fibre(SMF)with high stimulated Brillouin scattering(SBS)threshold which is co-doped with GeO_(2) and F_(2) in the core is *** increase the SBS threshold,the acousto−optic effective area is increased by designing a transverse acoustic waveguide and adjusting the doping level of GeO2 and F2 while the designed fiber retains a step optical refractive index *** optimal design is found by numerical simulation and the optimal fiber is fabricated by a plasma−activated chemical vapor deposition(PCVD)*** yields the threshold 6.79 dB,which is higher than the conventional single-mode fiber G.652 and 3dB higher than the Corning®SMF−28e+^(™)optical fiber with NexCor®technology.

关键词： fiber waveguide scattering

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The Power to Awaken A Heart

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Women of China 1998年第10期 38-39页

作者： tong wei CHEN SHANSHAN

THE process of reporting on women’s mental health is the process of studying and revealing the relation between matters of everyday life and women’s mental health. I have found that women hold different views on the... 详细信息

关键词： Zhang The Power to Awaken A Heart

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Memory Like A String of Pearls

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Women of China 1998年第8期 46-48页

作者： tong wei CHEN SHANSHAN

WANG Mingzhen is a wellknown Chinese physicist. Recently the 91-year-old woman looked back over the profoundly affecting experiences of her life. A Series of Setbacks As soon as she graduated from Peking University in 1930, Wang Mingzhen received an offer of admission from the University of Michigan in the United States. Although the school offered her a four-year scholarship for her tuition, she was penniless and could not afford the steamer ticket. Unwilling to seek help from her friends and relatives, Wang sent a letter declining admission, using her mother’s illness as an excuse. She could not know that this action would

关键词： In Memory Like A String of Pearls

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Chemistry and Application of Phosphonium and Arsonium Ylide(ⅩⅧ)——Stereoselective Syntheses of (Z)-3-Perfluoroalkyl--4-(3-Carboethoxy-2-f uranyl )-3-Butenoates

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Chemical Research in Chinese Universities 1992年第3期8卷 224-230页

作者： DING wei-yu , CAO wei-guo, ZHU Dian-kui and tong wei-qi (Department of Chemistry, Shanghai University of Science and Technology, Shanghai, 201800)

The stereoselective syntheses of (Z)-methyl 3-perfluoroalkyl-4-(3-carboethoxy-2-furanyl)-3-butenoates 5a-c were investigated. The reaction of (3-carboethoxy-2-fu-ranyl)-methyltriphenylphosphonium bromide 1 with methyl 2-perfluoroalkynoates 2a-c in the presence of K2CO3 at room temperature gives two adducts, (E)-methyl 3-per-fluoroalkyl-4-( 3-carboethoxy-2-furanyl )-2-triphenylphosphoranylidene-3-butenoates 3a-c and (E)-methyl 3-perfluoroalkyl-4-(3-carboethoxy-2-furanyl)-4-triphenylphos-phoranylidene-2-butenoates 4a-c. (Z)-Methyl 3-perfluoroalkyl-4-(3-carboethoxy-2-furanyl)-3-butenoates 5a-c can be synthesized stereoselectively with high yields when an aqueous DMF solution of 3c, 4c or a mixture of 3a-b and 4a-b was heated at 140℃ for 8 h.

关键词： (Z)-3-perfluoroalkyl-4-(3-carboethoxy-2-furanyl)-3-butenoate Phospho-rane Methyl 2-perfluoroalkynoate Hydrolysis Stereoselective synthesis

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Consensus on the Prevention of Type 2 Diabetes in Chinese Adults

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Chinese Medical Journal 2017年第5期130卷 600-606页

作者： Yu-Zhen tong Nan-wei tong wei-Ping Teng Yi-Ming MU Jia-Jun Zhao Zhong-Yan Shan Guang Ning Division of Endocrinology and Metabolism West China Hospital of Sichuan University Chengdu Sichuan 610041 China Division of Endocrinology The First Affiliated Hospital Chinese Medical University Shenyang Liaoning 110001 China Division of Endocrinology General Hospital of Chinese People's Liberation Army Beijing 100853 China Division of Endocrinology Shandong Provincial Hospital Jinan Shandong 250021 China Division of Endocrinology Shanghai Ruijin Hospital Shanghai Jiao Tong University Shanghai 200025 China

INTRODUCTIONHigh-risk population of Type 2 diabetes mellitus （T2DM） includes both euglycemic （normal glucose tolerance [NGT]） population with high risk of diabetes （EPWHROD） and prediabetic population. Between t... 详细信息

关键词： Adult Consensus Prediabetes Prevention Type 2 Diabetes

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考虑结伴行为的行人流场域元胞自动机模型

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系统工程理论与实践 2014年第9期34卷 2386-2391页

作者：童蔚苹程琳东南大学交通学院南京210096

与行人流疏散情景不同,在行人流聚集过程中,行人动力学特性具有一些显著的特点,如对目标位置的选择相对模糊不清,结伴同行的行人组凝聚力明显,组内行人存在着明显的跟随行为.论文以行人流聚集过程为研究对象,分析结伴行为对行人流聚集... 详细信息

与行人流疏散情景不同,在行人流聚集过程中,行人动力学特性具有一些显著的特点,如对目标位置的选择相对模糊不清,结伴同行的行人组凝聚力明显,组内行人存在着明显的跟随行为.论文以行人流聚集过程为研究对象,分析结伴行为对行人流聚集动力学的影响,扩展场域思想,提出一种扩展的行人流场域元胞自动机模型.模型运用感知区表示行人对周边环境的感知能力,提出用组内场对同伴间彼此凝聚、相互牵制的结伴行为进行建模.行人转移概率的计算新添了组内场因子并考虑了行人忽略场值的微小变化而保持原地不动的情景.模拟实验成功再现了行人对独立空间领域的需求和结伴行人的聚簇成团现象,讨论了行人组尺寸对聚集时间、行人间平均间距的影响.

关键词：行人聚集结伴行为组内场场域元胞自动机模型

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基于PSO-GA的Kriging插值法建立透地通信分层地层媒质模型

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煤炭学报 2016年第11期41卷 2913-2920页

作者：唐彤彤杨维邵小桃北京交通大学电子信息工程学院北京100044

地层层系的不同分布对透地通信电磁波的传播特性有重要影响。Kriging插值法利用地层媒质的有限采样点可有效建立分层地层媒质模型,其中的插值计算过程中变异函数模型参数的优化是准确构造地层分层模型的关键。为更好地解决由于采样点分... 详细信息

地层层系的不同分布对透地通信电磁波的传播特性有重要影响。Kriging插值法利用地层媒质的有限采样点可有效建立分层地层媒质模型,其中的插值计算过程中变异函数模型参数的优化是准确构造地层分层模型的关键。为更好地解决由于采样点分布不匀造成的插值点与采样点之间的误差,使求出的构建地层分界面的插值点更加逼近采样点,从而更精确地建立地层分层模型,提出了一种基于粒子群-遗传(PSO-GA)的Kriging插值法,对变异函数模型的参数进行优化。相比于基于PSO的Kriging插值法与基于GA的Kriging插值法,所提出的算法在粒子寻优迭代整个过程中通过粒子间的两次信息交换,不仅解决了陷入局部最优的问题,实现了全局最优样本,还加快了收敛的速度。仿真与分析结果表明采用所提出的基于PSO-GA的Kriging插值法建立透地通信分层地层媒质模型,相比于基于PSO的Kriging插值法与基于GA的Kriging插值法可获得更好的寻优性能及寻优稳定性。

关键词： Kriging插值法粒子群优化-遗传算法地层模型透地通信

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