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Effect of different molecular weight organic components on the increase of microbial growth potential of secondary effluent by ozonation

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Journal of Environmental Sciences 2014年第11期26卷 2190-2197页

作者： Xin Zhao Hong-Ying Hu tong yu Chang Su Haochi Jiang Shuming Liu Environmental Simulation and Pollution Control State Key Joint Laboratory School of Environment Tsinghua University State Environmental Protection Key Laboratory of Microorganism Application and Risk Control Graduate School at Shenzhen Tsinghua University College of Environment and Resources Inner Mongolia University

Ozonation has been widely applied in advanced wastewater treatment. In this study, the effect of ozonation on assimilable organic carbon （AOC） levels in secondary effluents was investigated, and AOC variation of different molecular weight （MW） organic components was analyzed. Although the removal efflciencies were 47%-76% and 94%-100% for UV2s4 and color at ozone dosage of 10 mg/L, dissolved organic carbon （DOC） in secondary effluents was hardly removed by ozonation. The AOC levels increased by 70%-780% at an ozone dosage range of 1-10 mg/L. AOC increased significantly in the instantaneous ozone demand phase, and the increase in AOC was correlated to the decrease in UV254 during ozonation. The results of MW distribution showed that, ozonation led to the transformation of larger molecules into smaller ones, but the increase in low MW （〈1 kDa） fraction did not contribute much to AOC production. The change of high MW （〉100 kDa and 10-100 kDa） fractions itself during ozonation was the main reason for the increase of AOC levels. Furthermore, the oxidation of organic matters with high MWs （〉 100 kDa and 10-100 kDa） resulted in more AOC production than those with low MWs （1-10 kDa and 〈1 kDa）. The results indicated that removing large molecules in secondary effluents could limit the increase of AOC during ozonation.

关键词： Wastewater reclamation and reuse Ozonation Assimilable organic carbon (AOC)Molecular weight distribution Biological stability

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Bubble Strategy—A Practical Solution to Return to Regular Life in the Intertwined Era of Vaccine Rollouts and Virus Mutation

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China CDC weekly 2022年第4期4卷 71-73页

作者： Ying Shen Da Huo tong yu Quanyi Wang Beijing Center for Disease Prevention and Control BeijingChina

For a long time,vaccination and herd immunity were considered to be the magic solution for controlling coronavirus disease 2019(COVID-19).However,the emergence of new variants altered people’s expectations and prolonged the pandemic duration,especially the Omicron strain with substantially increased transmissibility and decreased vaccine ***,we are in urgent need of a practical solution to resume regular life to some extent,while mitigating COVID-19 risks in the tight race between vaccine rollouts and virus *** commentary proposed that bubble strategy(or closed loop management),utilized in Tokyo 2020 Olympic Games and to be implemented in Beijing 2022 Winter Games,could serve as a novel technique of nonpharmaceutical interventions in coping with such a situation.

关键词： Regular resume utilized

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Experimental Study on the Sinking and Leveling of A Large-Capacity Offshore Wind Turbine Five-Bucket Foundation in Sand

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China Ocean Engineering 2024年第4期38卷 586-601页

作者： LIAN Ji-jian ZHU Hang GUO Yao-hua WANG Hai-jun yu tong-shun State Key Laboratory of Hydraulic Engineering Intelligent Construction and Operation Tianjin UniversityTianjin 300072China School of Civil Engineering Tianjin UniversityTianjin 300072China Tianjin University of Technology Tianjin 300384China College of Engineering Ocean University of ChinaQingdao 266100China

As offshore wind farms expand into deeper and farther ocean regions and the unit capacity of offshore wind turbines(OWTs)increases,there is a pressing need for a new foundation structure that can accommodate deep-sea conditions and support large capacities while maintaining economical and *** meet this goal of integrated transportation and one-step installation,a novel five-bucket jacket foundation(FBJF),with its suction installation and leveling methods in sand,has been proposed,analyzed and experimentally ***,seepage failure experiments of the FBJF at various depths were conducted,and a formula for calculating the critical suction of seepage failure suitable for the FBJF in sand was chosen and recommended for use with a range of values for the permeability coefficient ***,through leveling experiments of the FBJF at different depths,the maximum adjustable leveling angle during the sinking process was defined using seepage failure and the adjustable leveling angle of the foundation as control *** leveling control strategies were proposed and ***,an automatic sinking and leveling control system for the FBJF was developed and experimentally verified for feasibility.

关键词： offshore wind turbine(OWT) bucket foundation seepage failure suction installation

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Biotoxicity dynamic change and key toxic organics identification of coal chemical wastewater along a novel full-scale treatment process

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Journal of Environmental Sciences 2024年第4期138卷 277-287页

作者： Weiwei Ma Xiaoqi Zhang Hongjun Han Xueqing Shi Qiaoping Kong tong yu Fei Zhao School of Environmental and Municipal Engineering Qingdao University of TechnologyQingdao 266520China State Key Laboratory of Urban Water Resource and Environment Harbin Institute of TechnologyHarbin 150090China

It is particularly important to comprehensively assess the biotoxicity variation of industrial wastewater along the treatment process for ensuring the water environment ***,intensive studies on the biotoxicity reduction of industrial wastewater are still *** this study,the toxic organics removal and biotoxicity reduction of coal chemical wastewater(CCW)along a novel full-scale treatment process based on the pretreatment process-anaerobic process-biological enhanced(BE)process-anoxic/oxic(A/O)process-advanced treatment process was *** process performed great removal efficiency of COD,total phenol,NH_(4)^(+)-N and total *** the biotoxicity variation along the treatment units was analyzed from the perspective of acute biotoxicity,genotixicity and oxidative *** results indicated that the effluent of pretreatment process presented relatively high acute biotoxicity to Tetrahymena *** the acute biotoxicity was significantly reduced in BE-A/O *** the genotoxicity and oxidative damage to Tetrahymena thermophila were significantly decreased after advanced *** polar organics in CCW were identified as the main biotoxicity *** were positively correlated with acute biotoxicity,while the nitrogenous heterocyclic compounds and polycyclic aromatic hydrocarbons were positively correlated with *** the biotoxicity was effectively reduced in the novel full-scale treatment process,the effluent still performed potential biotoxicity,which need to be further explored in order to reduce environmental risk.

关键词： Acute biotoxicity Genotoxicity Oxidative damage Toxic organics Coal chemical wastewater Novel full-scale treatment process

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Radiative hydrodynamic simulations of the spectral characteristics of solar white-light flares

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Research in Astronomy and Astrophysics 2021年第1期21卷 1-14页

作者： yu-tong Yang Jie Hong Ying Li Ming-De Ding Hui Li Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210033China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China

As one of the most violent activities in the solar atmosphere,white-light flares(WLFs)are generally known for their enhanced white-light(or continuum)emission,which primarily originates in the solar lower ***,we know little about how white-light emission is *** this study,we aim to investigate the response of the continua at 3600Åand 4250Åand also the Hαand Lyαlines during WLFs modeled using radiative hydrodynamic *** take non-thermal electron beams as the energy source for the WLFs in two different initial atmospheres and vary their *** results show that the model with non-thermal electron beam heating clearly shows enhancements in the continua at 3600Åand 4250Åas well as in the Hαand Lyαlines.A larger electron beam flux,a smaller spectral index,or an initial penumbral atmosphere leads to a stronger emission increase at 3600Å,4250Åand in the Hα*** Lyαline,however,is more obviously enhanced in a quiet-Sun initial atmosphere with a larger electron beam spectral *** is also notable that the continua at 3600Åand 4250Åand the Hαline exhibit a dimming at the start of heating and reach their peak emissions after the peak time of the heating function,while the Lyαline does not show such *** results can serve as a reference for the analysis of future WLF observations.

关键词： methods:numerical radiative transfer Sun:atmosphere Sun:flares

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Overview of enhancing biological treatment of coal chemical wastewater:New strategies and future directions

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Journal of Environmental Sciences 2024年第1期135卷 506-520页

Coal chemical wastewater(CCW)is a type of refractory industrial wastewater,and its treatment has become the main bottleneck restricting the sustainable development of novel coal chemical *** treatment is considered as an economical,effective and environmentally friendly technology for CCW ***,conventional biological process is difficult to achieve the efficient removal of refractory organics because of CCW with the characteristics of composition complexity and high ***,seeking the novel enhancement strategy appears to be a favorable solution for enhancing biological treatment efficiency of *** review focuses on presenting a comprehensive picture about the exogenous enhancement strategies for CCW biological *** performance and potential application of exogenous enhancement strategies,including co-metabolic substrate enhancement,biofilm filler enhancement,adsorption material enhancement and conductive mediator enhancement,were ***,the enhancing mechanisms of different strategies were comprehensively discussed from a biological ***,the prospects of enhancement strategies based on the engineering performance,economic cost and environmental impact(3E)evaluation were *** novel enhancement strategy based on“low carbon emissions”,“resource recycling”and“water environment security”in the context of carbon neutrality was *** together,this review provides technical reference and new direction to facilitate the regulation and optimization of typical industrial wastewater biological treatment.

关键词： Coal chemical wastewater Biological treatment Exogenous enhancement Refractory organics 3E evaluation

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Effect of Jianpi Bushen Sequential Formula on Adjuvant Chemotherapy of Colon Cancer:Study Protocol for a Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2021年第12期27卷 891-895页

作者： ZHANG tong FEI yu-tong XU yun SUN Ling-yun HE Bin YAN Shao-hua TANG Mo YAN yun-zi MAO Jun YANG yu-fei Department of Oncology Xiyuan Hospital of China Academy of Chinese Medicine SciencesBeijing(100091)China Centre for Evidence-Based Chinese Medicine Beijing University of Traditional Chinese MedicineBeijing(100029)China Integrative Medicine Service Memorial Sloan Kettering Cancer CenterNew York(10041 NY 212)United States

Background The side effects of chemotherapy-induced nausea and vomiting(CINV)and myelosuppression reduce the cancer patients’adherence to *** Chinese patients choose Chinese medicine(CM)during chemotherapy to reduce side effects;however,the evidence is *** efficacy of a CM herbal treatment protocol,Jianpi Bushen Sequential Formula(健脾补肾续贯方,JBSF)will be evaluated on chemotherapy completion rate among patients with colon *** A multi-center double-blind randomized controlled trial(RCT)will be conducted on 400 patients with colon cancer who will receive 8 cycles of adjuvant chemotherapy with oxaliplatin and capecitabine(CAPEOX).Patients will be randomized 1:1 to receive the JBSF or placebo *** primary outcome is the overall chemotherapy completion *** secondary outcomes include individual chemotherapy completion rate,4-cycle completion rate of chemotherapy,time to treatment failure,relative dose intensity and treatment ***-up visits will be scheduled before every and after last *** This study will provide evidence on whether JBSF can improve the chemotherapy completion rate and reduce side effects among patients with colon cancer.(Trial registration:Clinical ***,***03716518)。

关键词： Chinese medicine Jianpi Bushen Sequential Formula Liujun Anwei Formula Qitu Erzhi Formula colon cancer chemotherapy induced nausea and vomiting myelosuppression

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A successful team treatment for left main shock syndrome

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Journal of Geriatric Cardiology 2013年第3期10卷 302-304页

作者： Bin Que yu-tong Cheng Hai Gao Xiao-tong Hou Ran Dong Nan Li Shao-Ping Nie Beijing Anzhen Hospital of the Capital University of Medical Sciences Beijing 100029 China

Acute myocardial infarction complicated by cardiogenic shock and left main coronary artery disease is called left main shock syndrome. It is reported that the morbility and mortality of the syndrome is approximately 0.46%and 55%-80%, respectively. However, the best treat-ment strategy in these cases is unknown. In this article, we present a patient with LMSS who successively underwent emergency percutane-ous coronary intervention and coronary artery bypass grafting with hemodynamic support within 5 days. The patient is now on his three month uneventful out-patient follow-up.

关键词： Dissection Graft patency Left internal mammary artery grafts

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DNA methylation-mediated expression of zinc finger protein 615 affects embryonic development in Bombyx mori

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Zoological Research 2022年第4期43卷 552-565页

作者： Guan-Feng Xu Cheng-Cheng Gong yu-Lin Tian tong-yu Fu Yi-Guang Lin Hao Lyu yu-Ling Peng Chun-Mei tong Qi-Li Feng Qi-Sheng Song Si-Chun Zheng Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology Guangzhou Key Laboratory of Insect Development Regulation and Applied ResearchInstitute of Insect Science and TechnologySchool of Life SciencesSouth China Normal UniversityGuangzhouGuangdong 510631China Division of Plant Science and Technology College of AgricultureFood and Natural ResourcesUniversity of MissouriColumbia MO 65211USA

Cell division and differentiation after egg fertilization are critical steps in the development of embryos from single cells to multicellular individuals and are regulated by DNA methylation via its effects on gene ***,the mechanisms by which DNA methylation regulates these processes in insects remain ***,we studied the impacts of DNA methylation on early embryonic development in Bombyx *** methylation and transcriptome analysis of early embryos showed that DNA methylation events mainly occurred in the 5'region of protein metabolism-related *** transcription factor gene zinc finger protein 615(ZnF615)was methylated by DNA methyltransferase 1(Dnmt1)to be up-regulated and bind to protein metabolism-related ***1 RNA interference(RNAi)revealed that DNA methylation mainly regulated the expression of nonmethylated nutrient metabolism-related genes through *** same sites in the ZnF615 gene were methylated in ovaries and *** of ZnF615 using CRISPR/Cas9 gene editing decreased the hatching rate and egg number to levels similar to that of Dnmt1 *** of the ZnF615 methylation rate revealed that the DNA methylation pattern in the parent ovary was maintained and doubled in the offspring ***,Dnmt1-mediated intragenic DNA methylation of the transcription factor ZnF615 enhances its expression to ensure ovarian and embryonic development.

关键词： DNA methylation Embryonic development Transcriptional regulation Epigenetic

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Role of brahma-related gene 1/brahma-associated factor subunits in neural stem/progenitor cells and related neural developmental disorders

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World Journal of Stem Cells 2023年第4期15卷 235-247页

作者： Nai-yu Ke Tian-Yi Zhao Wan-Rong Wang yu-tong Qian Chao Liu The First Clinical Medical College Anhui Medical UniversityHefei 230032Anhui ProvinceChina Institute of Stem cells and Tissue Engineering School of Basic Medical SciencesAnhui Medical UniversityHefei 230032Anhui ProvinceChina Department of Histology and Embryology School of Basic Medical SciencesAnhui Medical UniversityHefei 230032Anhui ProvinceChina

Different fates of neural stem/progenitor cells(NSPCs)and their progeny are determined by the gene regulatory network,where a chromatin-remodeling complex affects synergy with other ***,we review recent research progress indicating that the BRG1/BRM-associated factor(BAF)complex plays an important role in NSPCs during neural development and neural developmental *** studies based on animal models have shown that mutations in the BAF complex may cause abnormal neural differentiation,which can also lead to various diseases in *** discussed BAF complex subunits and their main characteristics in *** advances in studies of human pluripotent stem cells and the feasibility of driving their differentiation into NSPCs,we can now investigate the role of the BAF complex in regulating the balance between self-renewal and differentiation of *** recent progress in these research areas,we suggest that three approaches should be used in investigations in the near *** of whole human exome and genome-wide association studies suggest that mutations in the subunits of the BAF complex are related to neurodevelopmental *** insight into the mechanism of BAF complex regulation in NSPCs during neural cell fate decisions and neurodevelopment may help in exploiting new methods for clinical applications.

关键词： Neural stem/progenitor cell BRG1/BRM-associated factor complex Subunit Proliferation Differentiation Neural developmental disorde

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