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Chinese Optics Letters 2020年第7期18卷 23-27页

作者： Hiromi Sannomiya Naoki Takada tomoya Sakaguchi Hirotaka Nakayama Minoru Oikawa Yuichiro Mori Takashi Kakue Tomoyoshi Shimobaba Tomoyoshi Ito Graduate School of Integrated Arts and Sciences Kochi UniversityKochiKochi 780-8520Japan Research and Education Faculty Kochi UniversityKochiKochi 780-8520Japan National Astronomical Observatory of Japan MitakaTokyo 181-8588Japan Graduate School of Engineering Chiba UniversityChibaChiba 263-8522Japan

Systems containing multiple graphics-processing-unit(GPU)clusters are difficult to use for real-time electroholography when using only a single spatial light modulator because the transfer of the computer-generated hologram data between the GPUs is *** overcome this bottleneck,we propose a rapid GPU packing scheme that significantly reduces the volume of the required data *** proposed method uses a multi-GPU cluster system connected with a cost-effective gigabit Ethernet *** tests,we achieved real-time electroholography of a three-dimensional(3D)video presenting a point-cloud 3D object made up of approximately 200,000 points.

关键词： real-time electroholography multiple-graphics processing unit cluster graphics processing unit gigabit Ethernet

Relating brain structure images to personality characteristics using 3D convolution neural network

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CAAI Transactions on Intelligence Technology 2021年第3期6卷 338-346页

作者： Lixian Cao Yanchun Liang Wei Lv Kaechang Park Yasuhiro miura Yuki Shinomiya Shinichi Yoshida Zhuhai Laboratory of Key Laboratory of Symbol Computation and Knowledge Engineering of Ministry of Education Zhuhai College of Jilin UniversityZhuhaiChina Key Laboratory of Symbol Computation and Knowledge Engineering of Ministry of Education College of Computer Science and TechnologyJilin UniversityChangchunChina School of Information&Research Institute Kochi University of TechnologyKochiJapan

The Keras deep learning framework is employed to study MRI brain data in a preliminary analysis of brain structure using a convolutional neural *** results obtained are matched with the content of personality *** Big Five personality traits provide easy differentiation for dividing personalities into different *** now,the highest accuracy obtained from the results of personality prediction from the analysis of brain structure is about 70%.Although there is still no effective evidence to prove a clear relationship between brain structure and personality,the obtained results could prove helpful in understanding the basic relationship between brain structure and personality characteristics.

关键词： convolution structure dividing

Picosecond burst pulse machining with temporal energy modulation [Invited]

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Chinese Optics Letters 2020年第12期18卷 83-87页

作者： Akinao Nakamura Tomoki Mizuta Yasuhiko Shimotsuma Masaaki Sakakura Tomohito Otobe Masahiro Shimizu Kiyotaka miura Department of Material Chemistry Graduate School of EngineeringKyoto UniversityKyoto 615-8510Japan National Institutes for Quantum and Radiological Science and Technology Kansai Photon Science InstituteKyoto 619-0215Japan

Suppression of stress and crack generation during picosecond laser processing in transparent brittle materials such as glass was successfully demonstrated by a picosecond laser pulse with temporal energy *** origin of deterioration in processing accuracy could be interpreted in terms of the discontinuous movement of plasma in the vicinity of the *** reveal the effectiveness of the temporal energy modulation for smootli machining,such plasma motion was simulated by the fiidtc-d ifference time-domain method.F urt her more,photoinduced birefringence was observed using a high-speed polarization camera.

关键词： picosecond laser energy modulation burst pulse material processing stress distribution

Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review

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Cancer Drug Resistance 2021年第4期4卷 946-964页

作者： Shogo Ozawa Toshitaka miura Jun Terashima Wataru Habano Division of Pharmacodynamics and Molecular Genetics School of PharmacyIwate Medical UniversityYahabaIwate 0283694Japan

Treatment with pharmacological drugs for colorectal cancer(CRC)remains unsatisfactory.A major cause of failure in pharmacotherapy is the resistance of colon cancer cells to the drugs,creating an urgent *** this review,we summarize previous studies on the resistance of CRC cells to irinotecan and discuss possible reasons for *** review presents the following five major causes of irinotecan resistance in human CRC:(1)cellular irinotecan resistance is induced mainly through the increased expression of the drug efflux transporter,ABCG2;(2)cellular irinotecan resistance is also induced in association with a nuclear receptor,pregnane/steroid X receptor(PXR/SXR),which is enriched in the CYP3A4 gene enhancer region in CRC cells by exposing the cells to SN-38;(3)irinotecan-resistant cells possess either reduced DNA topoisomerase I(Top1)expression at both the mRNA and protein levels or Top1 missense mutations;(4)alterations in the tumor microenvironment lead to drug resistance through intercellular vesicle-mediated transmission of miRNAs;and(5)CRC stem cells are the most difficult targets to successfully treat *** the clinical setting,CRC gradually develops resistance to initially effective irinotecan-based *** solve this problem,several clinical trials,such as irinotecan plus cetuximab *** monotherapy,have been *** clinical trial on irinotecan plus guadecitabine,a DNA-methyltransferase inhibitor,has also been conducted.

关键词： Drug resistance colorectal cancer anti-cancer drugs irinotecan ABCG2 DNA topoisomerase I cancer stem cells epigenetics

Au/Ag_2O与Ag掺杂的Au粉催化剂上CO氧化反应:Au-Ag双金属催化剂活性位（英文）

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Chinese Journal of Catalysis 2016年第10期37卷 1712-1720页

作者： Yasuo Iizuka Yasuhiro Hiragi Hikaru Yakushiji Takumi miura 日本京都技术研究所研究生院化学与材料技术系日本京都606-8585 日本国立产业技术综合研究所(aist)大众能源研究部日本大阪563-8577

有关用于各种氧化反应中Au-Ag双金属催化剂存在显著协同效应的来源有两种观点:(1)AgO_x块与体相Au表面的接触界面起重要作用,体相Au的表面是催化活性位;(2)Au-Ag双金属催化剂中形成的Au-Ag合金中电荷从Ag转移到Au上,可能对催化剂活性起... 详细信息

有关用于各种氧化反应中Au-Ag双金属催化剂存在显著协同效应的来源有两种观点:(1)AgO_x块与体相Au表面的接触界面起重要作用,体相Au的表面是催化活性位;(2)Au-Ag双金属催化剂中形成的Au-Ag合金中电荷从Ag转移到Au上,可能对催化剂活性起作用.因此,确定Au表面上Ag是以氧化物还是以金属合金形式存在可能是深度理解该协同效应的关键.为了检测和验证催化剂活性的增加是由于Ag_2O与Au纳米粒子的紧密接触,在密闭循环反应体系中比较研究了Au/Ag_2O和Ag_2O催化剂上CO氧化反应.将CO/O_2摩尔比为2的混合气通入到这二个催化剂上来跟踪压力降低的速率.因而检测了气体的消耗量和CO_2的生成量.结果发现,在稳态下Au/Ag_2O和Ag_2O催化剂的压力降低的速率不存在差别.这两个催化剂上压力的降低是由于Ag_2O中表面晶格氧被混合气中CO的还原所致.Au/Ag_2O催化剂上得到的结果与以前研究的具有氧化表面的Ag掺杂的Au粉末(Ag/Au-b)上的一致,也表明AgO_x块与体相Au表面界面周边不大可能是CO氧化反应催化活性位.基于具有稳态表面的Ag/Au-b样品上的研究结果,我们认为AgO_x物种被还原为0价态Ag而形成的Ag-Au合金很可能是催化活性位.

关键词：金-银双金属催化剂协同效应一氧化碳氧化活性位金-银合金

Modification to poloidal charge exchange recombination spectroscopy measurement in JT-60U tokamak

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Chinese Physics B 2007年第11期16卷 3434-3442页

作者：丁伯江 Sakamoto Yoshiteru^b miura Yukitoshi^b Institute of Plasma Physics Chinese Academy of SciencesHefei230031China Japan Atomic Energy Agency Naka-machiNaka-gunIbaraki 311-0193Japan

With consideration of the effects of the atomic process and the sight line direction on the charge exchange re-combination spectroscopy （CXRS）, a code used to modify the poloidal CXRS measurement on Tokamak-60 Upgrade （JT-60U） in Japan Atomic Energy Research Institute is developed, offering an effective tool to modify the measurement and analyse experimental results further. The results show that the poloidal velocity of ion is overestimated but the ion temperature is underestimated by the poloidal CXRS measurement, and they also indicate that the effect of observation angle on rotation velocity is a dominant one in a core region （r/a 〈 0.65）, whereas in an edge region where the sight line is nearly normal to the neutral beam, the observation angle effect is very small. The difference between the modified velocity and the neoclassical velocity is not larger than the error in measurement. The difference inside the internal transport barrier （ITB） region is 2-3 times larger than that outside the ITB region, and it increases when the effect of excited components in neutral beam is taken into account. The radial electric field profile is affected greatly by the poloidal rotation term, which possibly indicates the correlation between the poloidal rotation and the transport barrier formation.

关键词： atomic process charge exchange recombination spectroscopy (CXRS) modification,plasma

Non-Contact Terahertz Inspection of Water Content in Concrete of Infrastructure Buildings

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World Journal of Engineering and Technology 2018年第2期6卷 275-281页

作者： Tadao Tanabe tomoya Kanai Kenta Kuroo tomoya Nishiwaki Yutaka Oyama Department of Materials Science Graduate School of Engineering Tohoku University Sendai Japan Department of Architecture and Building Science Graduate School of Engineering Tohoku University Sendai Japan

Concrete is the most widely used for construction materials in the world. Water content of concrete is an important parameter in terms durability of concrete structures. Terahertz (THz) waves, for which concrete is a porous and absorbable material, have been studied in order to establish a new non-contact inspection technology for maintenance of concrete structures. In this study, THz transmittance and reflectance of concrete in drying process were measured with a 60 GHz GUNN diode and absorption coefficient is analyzed for concrete with various water contents. It is shown that quantitative detection below 10% is possible for the water content at surface area of concrete.

关键词： Concrete Water Content Terahertz Wave Noncontact Inspection

Photoimmunotherapy for Local Recurrence of Nasopharyngeal Carcinoma: A Case Report

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International Journal of Otolaryngology and Head & Neck Surgery 2022年第5期11卷 258-265页

作者： Yukiomi Kushihashi Tatsuo Masubuchi Isaku Okamoto Chihiro Fushimi Kenji Hanyu Mayu Yamauchi Yuichiro Tada Koki miura Head and Neck Oncology Center International University of Health and Welfare Mita Hospital Tokyo Japan Department of Otorhinolaryngology Head and Neck Surgery Tokyo Medical University Tokyo Japan

Photoimmunotherapy (PIT), developed by the National Cancer Institute, involves Cetuximab sarotalocan sodium infusion followed by laser irradiation. PIT exerts specific antitumor effects on a variety of carcinomas that express epidermal growth factor receptors. PIT is a new cancer treatment option approved by Japan ahead of other countries worldwide. As of 2022, PIT is indicated in “unresectable, locally advanced, or locally recurrent head and neck cancer, with priority given to standard treatments such as chemotherapy when available”. The conventional treatment for unresectable locally advanced or locally recurrent head and neck cancer is palliative. Whether photoimmunotherapy can be curative for unresectable locally advanced head and neck cancers depends on the case. Herein, we report a case of locally recurrent nasopharyngeal carcinoma, treated with photoimmunotherapy via the nasal cavity, along with a literature review. Preoperative simulation provided considerable information on device selection, numbers of devices, and availability of working space. As a result, a complete response was obtained following a cylindrical diffuser puncture. Cases of local recurrence of nasopharyngeal carcinoma are considered a good indication for PIT. However, since the follow-up period after treatment was short in this case, we will continue to conduct strict follow-ups and accumulate more cases.

关键词： Photoimmunotherapy Nasopharyngeal Carcinoma Head and Neck Carcinoma Cetuximab Sarotalocan Sodium

Solvability of the Economic Input-Output Equation by Time Irreversibility

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Advances in Linear Algebra & Matrix Theory 2014年第3期4卷 143-155页

作者： Shinji miura Independent Gifu Japan

This paper reinterprets the economic input-output equation as a description of a realized situation without considering decision making. This paper uses the equation that the self-sufficiency rate is added to the Leontief type, and discusses its solvability. The equation has a unique solution if and only if each part of the relevant society satisfies the space-time openness condition. This condition means that commodities which a part of the relevant society possesses are not all inputted to its inside. Moreover, if the process of input and output is time irreversible, each part of the relevant society satisfies the space-time openness condition. Therefore, the solvability of the equation is guaranteed by time irreversibility. This proposition seems to be relevant to the grandfather paradox which is a type of time paradox.

关键词： Input-Output Equation Solvability Time Irreversibility Time Paradox

Fabrication of Bulk β-FeSi_2 Crystal With ThreeDimensional Alignment by an Oscillating Magnetic Field

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Journal of Iron and Steel Research(International) 2012年第S1期19卷 183-186页

作者： Noriaki Nakatsuka Keiji Kurokawa tomoya Nagira Masato Yoshiya Hideyuki Yasuda Department of Adaptive Machine Systems Osaka UniversityOsaka 565-0871Japan

It has been reported that an anisotropic magnetic field could produce the three-dimensional alignment of fine single-crystal particles with the orthorhombic crystal ***,the three-dimensional alignment was achieved only in *** of bulk 'single' materials that have the three-dimensional alignment of grains has been *** study proposes a procedure for the fabrication,which consists of slip casting under an oscillating magnetic field and *** of casting and sintering conditions achieved the three-dimensionally aligned bulk β-FeSi_2.

关键词： pseudo single crystal crystallographic orientation magnetic alignment