检索结果-南通市图书馆

Interleukin-17 levels in Helicobacter pylori-infected gastric mucosa and pathologic sequelae of colonization

World Journal of Gastroenterology 2005年第40期11卷 6305-6311页

作者： tomokazu mizuno Takafumi Ando Kazuo Nobata Tomoyuki Tsuzuki Osamu Maeda Osamu Watanabe Masaaki Minami Kenji Ina Kazuo Kusugami Richard M. Peek Hidemi Goto Department of Gastroenterology Division of Gastroenterology

AIM： To determine the role of interleukin （IL）-17 in gastric ulcerogenesis. METHODS： Thirty-six gastric ulcer （GU） patients and 29 non-ulcer （NU） patients were enrolled in this study. Mucosal biopsy samples were obtained from the gastric antrum and GU site during endoscopy. Samples were used in in situ stimulation for 48 h in the presence of 10 ug/mL phytohemagglutinin-P （PHA）, histological examination, and Helicobacter pylori（Hpylon） culture. IL-17 and IL-8 protein levels in culture supematants were assayed by ELISA. IL- 17 mRNA expression was analyzed by reverse transcriptasepolymerase chain reaction （RT-PCR）. Hpylori cagA and vacA status was assessed by reverse hybridization using a line probe assay （UPA）. IL-8 levels in culture supematants were assayed after AGS cells were co-cultured with Hpylori strain 26 695 or recombinant human （rh） IL-17. RESULTS： All 36 GU patients and 15 of 29 NU patients were found to be Hpy/or/-positive, while 14 NU patients were Hpylori-nogative. All 51 H pylori strains from both GU and NU patients were cagA- and vacAsl/ml-positive. Antral mucosal tissues from H pylori-positive patients contained significantly （H pylori-positive NU patients： median 467 pg/mg/protein, range 53-2 499; Hpylori negative NU patients： median 104 pg/mg/protein, range 16-312, P〈0.0005） higher levels of IL-17 than those from uninfected patients. IL-17 levels at the ulcer site were significantly （ulcer site： median 1 356 pcj/mg/protein, range 121-1 3730; antrum： median 761 pg/mg/protein, range 24-7 620, P〈0.005） higher than those at distant sites in the antrum. Biopsies from H pylori-positive GU and NU patients showed IL-17 mRNA expression in all samples whereas those from the antrum of the Hpylori-negativecontrols showed no detectable expression. A significant correlation was seen between IL-17 and IL-8 levels at each biopsy site （ulcer： r = 0.62,P〈0.0001; antrum： r = 0.61, P〈0.0001） in GU patients. RhIL-17 and Hpylori strain 26 695 each stimulated IL-8 product

关键词： Helicobacter pylori Gastric ulcer Histologicalgastritis Interleukin-17 Interleukin-8

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pedestrian trajectory prediction method based on the Social-LSTM model for vehicle collision

引用

Transportation Safety and Environment 2024年第3期6卷 140-151页

作者： Yong Han Xujie Lin Di Pan Yanting Li Liang Su Robert Thomson Koji mizuno School of Mechanical and Automotive Engineering Xiamen University of TechnologyXiamen 361024China Fujian Province Key Laboratory of Advanced Design and Manufacturing of Buses Xiamen 361024China Engineering Research Institute of Xiamen Kinglong United Automobile Industry Co. Ltd.Xiamen 361000China Chalmers University of Technology Gothenburg 41296Sweden Department of Mechanical Systems Engineering Nagoya UniversityNagoya 464-8603Japan

Techniques for predicting the trajectory of vulnerable road users are important to the development of perception systems for autonomous vehicles to avoid *** most effective trajectory prediction methods,such as Social-LSTM,are often used to predict pedestrian trajectories in normal passage ***,they can produce unsatisfactory prediction results and data redundancy,as well as difficulties in predicting trajectories using pixel-based coordinate systems in collision avoidance *** is also a lack of validations using real vehicle-to-pedestrian *** address these issues,some insightful approaches to improve the trajectory prediction scheme of Social-LSTM were proposed,such methods included transforming pedestrian trajectory coordinates and converting image coordinates to world *** YOLOv5 detection model was introduced to reduce target loss and improve prediction *** DeepSORT algorithm was employed to reduce the number of target transformations in the tracking *** Perspective Transformation(IPT)and Direct Linear Transformation(DLT)theories were combined to transform the coordinates to world coordinates,identifying the collision location where the accident could *** performance of the proposed method was validated by training tests using MS COCO(Microsoft Common Objects in Context)and ETH/UCY *** results showed that the target detection accuracy was more than 90%and the prediction loss tends to decrease with increasing training steps,with the final loss value less than 1%.The reliability and effectiveness of the improved method were demonstrated by benchmarking system performance to two video recordings of real pedestrian accidents with different lighting conditions.

关键词： vehicle-to-pedestrian collisions pedestrian trajectory prediction YOLOvB DeepSORT Social-LSTM

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pedestrian trajectory prediction method based on the Social-LSTM model for vehicle collision

引用

Transportation Safety and Environment 2024年第03期 158-169页

作者： Yong Han Xujie Lin Di Pan Yanting Li Liang Su Robert Thomson Koji mizuno School of Mechanical and Automotive Engineering Xiamen University of Technology Fujian Province Key Laboratory of Advanced Design and Manufacturing of Buses Engineering Research Institute of Xiamen Kinglong United Automobile Industry Co. Ltd. Chalmers University of Technology Department of Mechanical Systems Engineering Nagoya University

Techniques for predicting the trajectory of vulnerable road users are important to the development of perception systems for autonomous vehicles to avoid *** most effective trajectory prediction methods,such as Social-LSTM,are often used to predict pedestrian trajectories in normal passage ***,they can produce unsatisfactory prediction results and data redundancy,as well as difficulties in predicting trajectories using pixel-based coordinate systems in collision avoidance *** is also a lack of validations using real vehicle-to-pedestrian *** address these issues,some insightful approaches to improve the trajectory prediction scheme of Social-LSTM were proposed,such methods included transforming pedestrian trajectory coordinates and converting image coordinates to world *** YOLOv5 detection model was introduced to reduce target loss and improve prediction *** DeepSORT algorithm was employed to reduce the number of target transformations in the tracking *** Perspective Transformation(IPT) and Direct Linear Transformation(DLT) theories were combined to transform the coordinates to world coordinates,identifying the collision location where the accident could *** performance of the proposed method was validated by training tests using MS COCO(Microsoft Common Objects in Context) and ETH/UCY *** results showed that the target detection accuracy was more than 90% and the prediction loss tends to decrease with increasing training steps,with the final loss value less than 1%.The reliability and effectiveness of the improved method were demonstrated by benchmarking system performance to two video recordings of real pedestrian accidents with different lighting conditions.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Current perspectives of viral

引用

World Journal of Gastroenterology 2024年第18期30卷 2402-2417页

作者： Daisuke Usuda Yuki Kaneoka Rikuo Ono Masashi Kato Yuto Sugawara Runa Shimizu Tomotari Inami Eri Nakajima Shiho Tsuge Riki Sakurai Kenji Kawai Shun Matsubara Risa Tanaka Makoto Suzuki Shintaro Shimozawa Yuta Hotchi Ippei Osugi Risa Katou Sakurako Ito Kentaro Mishima Akihiko Kondo Keiko mizuno Hiroki Takami Takayuki Komatsu Tomohisa Nomura Manabu Sugita Department of Emergency and Critical Care Medicine Juntendo University Nerima HospitalNerima 177-8521TokyoJapan Department of Sports Medicine Faculty of MedicineJuntendo UniversityBunkyo 113-8421TokyoJapan

Viral hepatitis represents a major danger to public health,and is a globally leading cause of *** five liver-specific viruses:Hepatitis A virus,hepatitis B virus,hepatitis C virus,hepatitis D virus,and hepatitis E virus,each have their own unique epidemiology,structural biology,transmission,endemic patterns,risk of liver complications,and response to antiviral *** remain few options for treatment,in spite of the increasing prevalence of viral-hepatitiscaused liver ***,chronic viral hepatitis is a leading worldwide cause of both liver-related morbidity and mortality,even though effective treatments are available that could reduce or prevent most patients’*** 2016,the World Health Organization released its plan to eliminate viral hepatitis as a public health threat by the year 2030,along with a discussion of current gaps and prospects for both regional and global eradication of viral ***,treatment is sufficiently able to prevent the disease from reaching advanced ***,future therapies must be extremely safe,and should ideally limit the period of treatment necessary.A better understanding of pathogenesis will prove beneficial in the development of potential treatment strategies targeting infections by viral *** review aims to summarize the current state of knowledge on each type of viral hepatitis,together with major innovations.

关键词： Hepatitis A virus Hepatitis B virus Hepatitis C virus Hepatitis D virus Hepatitis E virus Current perspectives

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Grain refining in weld metal using short-pulsed laser ablation during CW laser welding of 2024-T3 aluminum alloy

引用

International Journal of Extreme Manufacturing 2019年第4期1卷 34-41页

作者： Masaki Kasuga tomokazu Sano Akio Hirose Division of Materials and Manufacturing Science Graduate School of EngineeringOsaka University2-1 Yamada-okaSuitaOsaka 565-0871Japan

The 2024 aluminum alloy is used extensively in the aircraft and aerospace industries because of its excellent mechanical ***,the weldability of 2024 aluminum alloy is generally low because it contains a high number of solutes,such as copper(Cu),magnesium(Mg),and manganese(Mn),causing solidification *** high speed welding of 2024 aluminum alloy without the use of filler is achieved,the applicability of 2024 aluminum alloys will *** refining is one of the methods used to prevent solidification cracking in weld metal,although it has never been achieved for high-speed laser welding of 2024 aluminum alloy without ***,we propose a short-pulsed,laser-induced,grain-refining method during continuous wave laser welding without ***-on-plate welding was performed on a 2024-T3 aluminum alloy at a welding speed of 1 m min−1 with a single mode fiber laser at a wavelength of 1070 nm and power of 1 *** in and around the molten pool were irradiated with nanosecond laser pulses at a wavelength of 1064 nm,pulse width of 10 ns,and pulse energy of 430 *** grain-refinement effect was confirmed when laser pulses were irradiated on the molten *** grain-refinement region was formed in a semicircular shape along the solid–liquid *** of the vertical section indicate that the grain-refinement region reached a depth of 1 mm along the solid–liquid *** Vickers hardness test results demonstrated that the hardness increased as a result of grain refinement and that the progress of solidification cracking was suppressed in the grain refinement region.

关键词： 2024 aluminum alloy hot cracking laser welding grain refinement dendrite fragmentation short pulsed laser laser ablation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Formation of Low Aspect Ratio Torus Equilibria by ECH in the LATE Device

引用

Plasma Science and Technology 2006年第1期8卷 95-98页

作者： Takashi MAEKAWA Hitoshi TANAKA Masaki UCHIDA tomokazu YOSHINAGA Graduate School of Energy Science Kyoto UniversityKyoto 606-8502Japan

By ECH under a steady By field, a closed field equilibrium of a low aspect ratio as low as R/a = 1.4 is spontaneously formed in the LATE device. After the spontaneous formation, the plasma current has increased further up to Ip = 7.2 kA by 2.45 GHz, 30 kW and Ip = 11 kA by 5 GHz, 120 kW, by increasing the microwave power with a slow ramp of By for the equilibrium of the plasma loop at larger currents. Both amount to 12% of the total toroidai coil current. ECH/ECCD at 2nd harmonic resonance of EBW supports the plasma. An outline of the theoretical considerations for the formation process is presented.

关键词： ECH spherical tokamaks non-inductive start-up

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Novel Sterilization Method Using Pulsed Discharge Plasma

引用

Chinese Physics Letters 1998年第1期15卷 41-42页

作者： WANG Xi-lu Akira mizuno Shijin Katsura Department of Ecological Engineering Toyohashi University of TechnologyTempaku-choToyohashi441Japan Institute of Electrostatics Northeast Normal UniversityChangchun 130024

Pulsed discharge plasma(PDP)has been used to kill bacteria and the curves of the survival rate of bacteria against treatment time are *** structural change in the cell membrane is caused by PDP and the cell is thus **... 详细信息

关键词： PDP Plasma treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats

引用

World Journal of Gastroenterology 2014年第10期20卷 2641-2652页

作者： Atsuki Yamamoto tomokazu Itoh Reishi Nasu Ryuichi Nishida Pharmaceutical research laboratories Sakai Chemical Industry Co. Ltd. Kawachinagano Osaka 586-0006 Japan KATAYAMA SEIYAKUSYO Co. Ltd.Hirakata Osaka 573-1132 Japan Kaigen Pharma Co. Ltd.Doshomachi Chuo-ku Osaka 541-0045 Japan

AIM: To investigate the effects of sodium alginate (AL-Na) on indomethacin-induced small intestinal lesions in rats.

关键词： Sodium alginate Non-steroidal anti-inflammatory drugs Gastrointestinal mucosal injury Mucin Bacterial translocation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Study of Electron Orbits for Formation of Toroidal Closed Flux Surface by ECH

引用

Plasma Science and Technology 2011年第3期13卷 342-346页

作者： Tak,ushi MAEKAWA tomokazu YOSHINAGA Hitoshi TANAKA Masaki UCHIDA Fumitake WATANABE Graduate School of Energy Science Kyoto University Kyoto 606-8502 Japan National Institute for Fusion Science Toki 509-5292 Japan

Electron orbits under the external vertical field （Bv） and the self poloidal field of the toroidal plasma current in a toroidal geometry are investigated by using analytic model fields in order to search for the conditions of occurence of appropriate confinement asymmetry of fast electrons along the field lines. This asymmetry efficiently and quickly generates a toroidal current, which may close the field lines in ECH-started plasmas. It is analytically shown that the characteristics of confinement asymmetry depend on the product of the major radius and the strength of the external vertical field. The results suggest that in large devices By should be lowered and also some artificial means to speed up the pitch angle scattering for the fast electrons at a higher energy range are beneficial to generate the toroidal current in order to close the filed

关键词： ECH closed flux surface electron orbit

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Novel Estimating Method for Steering Efficiency of the Driver with Electromyography Signals

引用

Chinese Journal of Mechanical Engineering 2014年第3期27卷 460-467页

作者： LIU Yahui JI Xuewu HAYAMA Ryouhei mizuno Takahiro State Key Laboratory of Automotive Safety and Energy Tsinghua University Research and Development Center jtekt co.ltd.

The existing research of steering efficiency mainly focuses on the mechanism efficiency of steering system, aiming at designing and optimizing the mechanism of steering system. In the development of assist steering system especially the evaluation of its comfort, the steering efficiency of driver physiological output usually are not considered, because this physiological output is difficult to measure or to estimate, and the objective evaluation of steering comfort therefore cannot be conducted with movement efficiency perspective. In order to take a further step to the objective evaluation of steering comfort, an estimating method for the steering efficiency of the driver was developed based on the research of the relationship between the steering force and muscle activity. First, the steering forces in the steering wheel plane and the electromyography （EMG） signals of the primary muscles were measured. These primary muscles are the muscles in shoulder and upper ann which mainly produced the steering torque, and their functions in steering maneuver were identified previously. Next, based on the multiple regressions of the steering force and EMG signals, both the effective steering force and the total force capacity of driver in steering maneuver were calculated. Finally, the steering efficiency of driver was estimated by means of the estimated effective force and the total force capacity, which represented the information of driver physiological output of the primary muscles. This research develops a novel estimating method for driver steering efficiency of driver physiological output, including the estimation of both steering force and the force capacity of primary muscles with EMG signals, and will benefit to evaluate the steering comfort with an objective perspective.

关键词： electromyography muscle activity steering efficiency estimating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：