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Application of the Level-Set Model with Constraints in Image Segmentation

Numerical Mathematics(Theory,Methods and Applications) 2016年第1期9卷 147-168页

作者： Vladimiır Klement tomas oberhuber Daniel Sevcovic Department of Mathematics Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueTrojanova 13Praha 212000Czech Republic Department of Applied Mathematics and Statistics Comenius University84248 BratislavaSlovakia

We proposeand analyze a constrained level-set method forsemi-automatic image *** level-set model with constraints on the level-set function enables us to specify which parts of the image lie inside respectively outside the segmented *** a-priori information can be expressed in terms of upper and lower constraints prescribed for the level-set *** have the same conceptual meaning as initial seeds of the popular graph-cuts based meth-ods for image segmentation.A numerical approximation scheme is based on the complementary-finite volumes method combined with the Projected successive over-relaxation method adopted for solving constrained linear complementarity *** advantage of the constrained level-set method is demonstrated on several artificial images as well as on cardiac MRI data.

关键词： linear complementarity image processing segmentation level-set method projected successive over-relaxation method

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Ischemia and reperfusion injury of the spinal cord:experimental strategies to examine postischemic paraplegia

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Neural Regeneration Research 2016年第3期11卷 414-415页

作者： Florian Simon Alexander oberhuber Clinic for Vascular-and Endovascular Surgery Heinrich-Heine-University

Thoracoabdominal aortic replacement,necessary in case of injuries,aneurysms and dissections,shows a high complication rate as a consequence of the perioperative ischemia/reperfusion-sequence（I/R）.Clamping above and below the lesion leads to the spinal cord suffering from *** times of less than 30 minutes show only a small risk of neurological deficit,

关键词： deficit minutes neurological replacement injuries suffering consequence longer thoracic subsequent

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Multiple cerebral lesions in a patient with refractory celiac disease:A case report

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World Journal of Gastroenterology 2020年第47期26卷 7584-7592页

作者： Lena Horvath Georg oberhuber Andreas Chott Maria Effenberger Herbert Tilg Eberhard Gunsilius Dominik Wolf Sarah Iglseder Department of Internal Medicine V(Hematology and Medical Oncology) Medical University InnsbruckInnsbruck 6020Austria InnPath GmbH Institute of PathologyInnsbruck 6020Austria Ottakring Clinic Institute of Pathology and MicrobiologyVienna 1160Austria Department of Internal Medicine I(Gastroenterology HepatologyEndocrinology and Metabolism)Medical University InnsbruckInnsbruck 6020Austria Department of Neurology Medical University InnsbruckInnsbruck 6020Austria

BACKGROUND Enteropathy-associated T cell lymphoma(EATL)is an aggressive intestinal T cell lymphoma derived from intraepithelial lymphocytes,which occurs in individuals with celiac disease(CD).Cerebral involvement is an extremely rare condition and as described so far,lymphoma lesions may present as parenchymal predominantly supratentorial or leptomeningeal *** describe a case of EATL with multifocal supra-and infratentorial brain involvement in a patient with refractory celiac disease(RCD).CASE SUMMARY A 58-years old man with known CD developed ulcerative jejunitis and was diagnosed with RCD type *** months later he presented with subacute cerebellar symptoms(gait ataxia,double vision,dizziness).Cranial magnetic resonance imaging(MRI)revealed multifocal T2 hyperintense supra-and infratentorial *** studies of blood and cerebrospinal fluid were inconspicuous for infectious,inflammatory or autoimmune diseases.18Ffluorodeoxyglucose-positron emission tomography/computed tomography(18FDG-PET/CT)scan showed a suspect hypermetabolic lesion in the left upper abdomen and consequent surgical jejunal resection revealed the diagnosis of *** the diagnostic work-up,neurological symptoms aggravated and evolved refractory to high-dosage *** MRI scans showed progressive cerebral lesions,highly suspicious for lymphoma and methotrexate chemotherapy was ***,clinically the patient responded only ***,cerebral biopsy confirmed the diagnosis of cerebral involvement of *** the poor prognosis and deterioration of the performance status,best supportive care was *** patient passed away three weeks after *** EATL with cerebral involvement must be considered as a possible differential diagnosis in patients with known RCD presenting with neurological symptoms.

关键词： Enteropathy-associated T cell lymphoma Brain neoplasm Celiac disease Cerebellar syndrome Case report

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Helicobacter pylori and gastric cancer: current status of the Austrian-Czech-German gastric cancer prevention trial (PRISMA-Study)

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World Journal of Gastroenterology 2001年第2期7卷 243-247页

作者： S.Miehlke C.Kirsch B.Dragosics M.Gschwantler G.oberhuber D.Antos P.Dite J.Lauter J.Labenz A.Leodolter P.Malfertheiner A.Neubauer G.Ehninger M.Stolte E.Bayerdorffer Medical Department I GastroenterologyHematologyOncologyPulmonology & Infectious DiseasesTechnical University Hospital Carl Gustav CarusDresdenGermany Gesundheitszentrum Süd ViennaAustria Medical Department 4 Krankenanstalt RudolfstiftungViennaAustria Institute for Pathology General HospitalViennaAustria Surgical Department Ludwig-Maximilians-University Hospital GroβhadernMunichGermany Univerzitni nemocnice Jihlavska Brno-BohuniceCzech Republic Institute for Medical Statistics Otto-von-Guericke-UniversityMagdeburgGermany Department of Medicine Evang. Jung-Stilling HospitalSiegenGermany Department of Gastroenterology Otto-v.-Guericke University HospitalMagdeburgGermany Department for Hematology Oncology&ImmunologyUniversity Hospital MarburgGermany Institute of Pathology Klinikum BayreuthBayreuthGermany

AIM To test the hypothesis that Helicobacter pylori eradication alone can reduce the incidence of gastric cancer in a subgroup of individuals with an increased risk for this fatal *** It is a prospective, randomized,double-blind, placebo-controlled multinational multicenter trial. Men between 55 and 65 years of age with a gastric cancer phenotype of Helicobacterpylori gastritis are randomized to receive a 7-day course of omeprazole 2 × 20 mg,clarithromycin 2 × 500 mg, and amoxicillin 2 ×lg for 7 days, or omeprazole2 × 20mg plusplacebo. Follow - up endoscopy is scheduled 3months after therapy, and thereafter in one-year intervals. Predefined study endpoints are gastric cancer, precancerous lesions (dysplasia, adenoma), other cancers, *** Since March 1998, 1524 target patients have been screened, 279 patients (18.3%) had a corpus-dominant type of *** gastritis, and 167 of those were randomized (58.8%). In the active treatment group (n -- 86), H. pylori infection infection was cured in 88.9% of patients. Currently, thecumulative follow-up time is 3046 months (253.8patient-years, median follow-up 16 months). So far, none of the patients developed gastric cancer or any precancerous lesion. Three(1.8%) patients reached study endpoints other than gastric *** Among men between 55 and 65years of age, the gastric cancer phenotype of *** gastritis appears to be more common than expected. Further follow- up and continuing recruitment are necessary to fulfil the main aim of the study.

关键词： Helicobacter pylori Helicobacter infections/complications Helicobacter infections/drug therapy stomach neoplasms /microbiology stomach neoplasms/drug therapy gastritis/microbiology gastritis/drug therapy

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应用MRI评估复合性外伤病人胸部血管支架急诊植入的可行性研究

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国际医学放射学杂志 2011年第5期 495-495页

作者： V.Rasche A.oberhuber S.Trumpp A.Bornstedt K.H.Orend N.Merkle 沈晶 Department of Internal Medicine II University Hospital Ulm University of Ulm

目的本研究旨在探讨应用MRI方法静态和动态评估外伤病人胸主动脉支架急诊植入后形态与功能状态的可行性。方法 20例以胸主动脉破裂为表现的急诊病人被纳

关键词：胸主动脉腔内修复 MRI CT 电影成像

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