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Natural variations of HvSRN1 modulate the spike rachis node number in barley

Plant Communications 2024年第1期5卷 148-163页

作者： Chaofeng Fan Dongdong Xu Chunchao wang Zhaoyan Chen tingyu Dou Dandan Qin Aikui Guo Meng Zhao Honghong Pei Mengwei Zhao Renxu Zhang Ke wang Jing Zhang Zhongfu Ni Ganggang Guo Key Laboratory of Grain Crop Genetic Resources Evaluation and Utilization(MARA) The National Key Facility for Crop Gene Resources and Genetic ImprovementInstitute of Crop SciencesChinese Academy of Agricultural Sciences(ICS-CAAS)Beijing 100081China Hainan Yazhou Bay Seed Laboratory Sanya 572025China Institute of Industrial Crops Shandong Academy of Agricultural SciencesJinan 250100China Key Laboratory of Crop Heterosis and Utilization Beijing Key Laboratory of Crop Genetic ImprovementChina Agricultural UniversityBeijing 100193China Key Laboratory for Crop Molecular Breeding of Ministry of Agriculture and Rural Affairs Institute of Food CropsHubei Academy of Agricultural SciencesWuhan 430064China

Grain number,one of the major determinants of yield in Triticeae crops,is largely determined by spikelet number and spike rachis node number(SRN).Here,we identified three quantitative trait loci(QTLs)for SRN using 145 recombinant inbred lines derived from a barley R90/1815D ***1,the major-effect QTL,was mapped to chromosome 2H and explained up to 38.77%of SRN ***-based cloning revealed that qSRN1 encodes the RAWUL domain-containing protein *** analysis revealed that two key SNPs in the HvSRN1 promoter region(-2 kb upstream of the transcription start site)affect the transcript level of HvSRN1 and contribute to variation in *** to its orthologous proteins OsLAX2 and ZmBA2,HvSRN1 showed protein–protein interactions with HvLAX1,suggesting that the LAX2–LAX1 model for spike morphology regulation may be conserved in Poaceae ***-Cas9-induced HvSRN1 mutants showed reduced SRN but increased grain size and weight,demonstrating a trade-off *** results shed light on the role of HvSRN1 variation in regulating the balance between grain number and weight in barley.

关键词： barley fine-mapping grain number kernel weight

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makeTwin:A reference architecture for digital twin software platform

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Chinese Journal of Aeronautics 2024年第1期37卷 1-18页

作者： Fei TAO Xuemin SUN Jiangfeng CHENG Yonghuai ZHU Weiran LIU Yong wang Hui XU Tianliang HU Xiaojun LIU tingyu LIU Zheng SUN Jun XU Jinsong BAO Feng XIANG Xiaohui JIN Digital Twin International Research Center International Research Institute for Multidisciplinary ScienceBeihang UniversityBeijing 100191China School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China Institute of Advanced Manufacturing and Intelligent Technology Beijing University of TechnologyBeijing 100124China RIAMB(Beijing)Technology Development Co Ltd(R.T.D.)Beijing 100120China School of Mechanical Engineering Shandong UniversityJinan 250061China School of Mechanical Engineering Southeast UniversityNanjing 211189China School of Mechanical Engineering Xi’an Jiaotong UniversityXi’an 710049China College of Mechanical Engineering Donghua UniversityShanghai 201620China School of Machinery and Automation Wuhan University of Science and TechnologyWuhan 430081China Beijing Aero-top Hi-tech Co LtdBeijing 100176China

Digital twin is currently undergoing a significant transformation from the conceptual and theoretical research phase to the implementation and application ***,a universally adaptable research and development platform for digital twin is critically needed to meet the development ***,a publicly accessible simulation,testing,and validation platform which can support digital twin model building,data processing,algorithm design,configuration,etc.,is urgently required for ***,for developers from the industry,a lowcode development platform that can offer a customizable suite of functions such as model creation,data management,protocol configuration,and visualization is urgently ***,for enterprise users,there is a lack of an application management platform that can be configured and migrated for various application scenarios,functions,and ***,based on the system research of digital twin theories and key technologies by the authors(such as the five-dimension digital twin model,digital twin modeling and digital twin data theory,digital twin standards,and so on),a digital twin software platform reference architecture,namely make Twin,is proposed and designed,as well as its ten core *** workflow of the make Twin and the interaction mechanisms among its core functions are ***,a digital twin application system for a chemical fiber textile shop floor(CFTS)which was developed according to make Twin,is introduced,which validates the proposed reference architecture.

关键词： Digital twin Digital twin software platform Industrial software makeTwin Reference architecture

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加强考前培训提高就业竞争力

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中国职业技术教育 2007年第36期23卷 30-31页

作者：汪亭玉江苏海事职业技术学院江苏南京210011

《船舶辅机》是航海轮机管理专业的一门专业课程，是提高远洋船员证书考试合格率的重要课程。本文从《船舶辅机》考前辅导的角度探讨了其教学方法，并从中总结出考试培训的一些共性问题。

关键词：船舶辅机考前辅导考证培训

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Photobiomodulation inhibits the expression of chondroitin sulfate proteoglycans after spinal cord injury via the Sox9 pathway

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Neural Regeneration Research 2024年第1期19卷 180-189页

作者： Zhihao Zhang Zhiwen Song Liang Luo Zhijie Zhu Xiaoshuang Zuo Cheng Ju Xuankang wang Yangguang Ma tingyu Wu Zhou Yao Jie Zhou Beiyu Chen Tan Ding Zhe wang Xueyu Hu Department of Orthopedics Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina

Both glial cells and glia scar greatly affect the development of spinal cord injury and have become hot spots in research on spinal cord injury *** cellular deposition of dense extracellular matrix proteins such as chondroitin sulfate proteoglycans inside and around the glial scar is known to affect axonal growth and be a major obstacle to autogenous *** proteins are thus candidate targets for spinal cord injury *** previous studies demonstrated that 810 nm photo biomodulation inhibited the formation of chondroitin sulfate proteoglycans after spinal cord injury and greatly improved motor function in model ***,the specific mechanism and potential targets involved remain to be *** this study,to investigate the therapeutic effect of photo biomodulation,we established a mouse model of spinal cord injury by T9 clamping and irradiated the injury site at a power density of 50 mW/cm~2 for 50 minutes once a day for 7 consecutive *** found that photobiomodulation greatly restored motor function in mice and down regulated chondroitin sulfate proteoglycan expression in the injured spinal *** analysis revealed that photobiomodulation inhibited the expression of proteoglycan-related genes induced by spinal cord injury,and versican,a type of proteoglycan,was one of the most markedly changed *** staining showed that after spinal cord injury,versican was present in astrocytes in spinal cord *** expression of versican in primary astrocytes cultured in vitro increased after inflammation induction,whereas photobiomodulation inhibited the expression of ve ***,we found that the increased levels of p-Smad3,p-P38 and p-Erk in inflammatory astrocytes were reduced after photobiomodulation treatment and after delivery of inhibitors including FR 180204,(E)-SIS3,and SB *** suggests that Sma d 3/Sox9 and MAP K/Sox9 pathways may be involved in the effects of photobiomodulatio

关键词： chondroitin sulfate proteoglycans Erk MAPK P38 photobiomodulation principal component analysis Smad3 Sox9 spinal cord injury versican

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Cytogenetic aberrations of lymphoplasmacytic lymphoma/ Waldenström’s macroglobulinemia in Chinese patients

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Chinese Medical Journal 2023年第10期136卷 1240-1242页

作者： Wenjie Xiong tingyu wang Ying Yu Yang Jiao Jiawen Chen Yi wang Chengwen Li Rui Lyu Qi wang Wei Liu Weiwei Sui Gang An Dehui Zou Lugui Qiu Shuhua Yi State Key Laboratory of Experimental Hematology National Clinical Research Center for Blood DiseasesHaihe Laboratory of Cell EcosystemInstitute of Hematology&Blood Diseases HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300020China Tianjin Institutes of Health Science Tianjin 301600China

To the Editor:As a rare indolent B cell non-Hodgkin lymphoma,lymphoplasmacytic lymphoma/Waldenström’s macroglobulinemia(LPL/WM)has unique clinical and biological characteristics.[1]However,due to the difficulties in obtaining tumor metaphase for karyotyping and slow cell proliferation,only very few studies have detected the cytogenetic aberration of LPL/WM.[2,3]In addition,6q deletion is the most common cytogenetic aberration in WM,with an incidence rate of about 50%.[2]Nevertheless,other cytogenetic aberrations remain largely unclear,and the prognostic role of cytogenetic aberrations needs to be further *** the present study,we systematically analyzed 305 LPL/WM cases in China,focusing on the characteristics and cytogenetic aberrations in Chinese patients.

关键词： lymphoma patients globulin

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船舶柴油机主轴承同轴度的CMOS测量方法

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船海工程 2007年第6期36卷 59-62页

作者：汪亭玉江苏海事职业技术学院轮机工程系南京211170

给出一种中型以上船舶主机支承孔同轴度的CMOS测量方法。其安装测量基准线采用带单模尾纤的准直半导体激光,轴孔中心位置传感器由CMOS面阵与旋转电感量头组成。实验结果表明,该方法不仅完全可以满足船舶主机支承孔同轴度测量的精度要求... 详细信息

给出一种中型以上船舶主机支承孔同轴度的CMOS测量方法。其安装测量基准线采用带单模尾纤的准直半导体激光,轴孔中心位置传感器由CMOS面阵与旋转电感量头组成。实验结果表明,该方法不仅完全可以满足船舶主机支承孔同轴度测量的精度要求,而且具有良好的经济性和灵活性。

关键词：同轴度测量激光准直 CMOS图像传感器位置传感器

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粒径对煤温和气化特性的影响

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煤炭转化 1999年第3期22卷 39-43页

作者：朱廷钰王洋中国科学院山西煤炭化学研究所气化室太原030001

用神木煤在鼓泡流化床反应品中进行了两个粒往下煤温和气化特性研究，结果表明：当不添加氧化钙时，由于在热解过程中形成了基本相同的煤层厚度，传热和传质条件都很接近，所以此时颗粒尺寸与温和气化产物关系不大．添加氧化钙后，由于... 详细信息

用神木煤在鼓泡流化床反应品中进行了两个粒往下煤温和气化特性研究，结果表明：当不添加氧化钙时，由于在热解过程中形成了基本相同的煤层厚度，传热和传质条件都很接近，所以此时颗粒尺寸与温和气化产物关系不大．添加氧化钙后，由于氧化钙减少了温和气化过程中煤的熔聚性，防止了煤样团聚，从而使煤样粒径对温和气化过程发生了影响．在450℃～650℃范围内，粒径增大气态产率增加．650℃～750℃范围内，粒径增大气态产率减小．最后，对两种粒径下所得半焦进行了工业分析和元素分析，并对所得结果进行了讨论．

关键词：温和气化粒径流化床反应器气化煤

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Plumbagin Inhibits Inflammatory Response and Bone Loss in Experimental Chronic Peridontitis Rats

Plumbagin Inhibits Inflammatory Response and Bone Loss in Ex...

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中华口腔医学会第六次全国口腔药学学术会议

作者： tingyu wang Xinyi Zheng Han Qiao Fang Gu Yunwu Li Feihua Wu Department of Pharmacy Shanghai Ninth People's Hospital Shanghai JiaoTong University School of Medicine College of Stomatology Shanghai JiaoTong University School of Medicine Shanghai Key Laboratory of Orthopaedic Implant Department of Orthopaedics Surgery Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine

Aim Chronic periodontitis(CP) is one of the most common oral diseases which causes alveolar bone absorption and tooth loss in adults. In this study,we aimed to remedy chronic periodontitis with Plumbagin(PL), one widely-investigated pharmacologic drug derived from traditional Chinese medical herb. Methods Experimental chronic peridontitis is established by ligate and Porphyromonas gingivalis(Pg) stimulation in Sprague-Dawley rats(SD rats). The rats were injected with PL(2, 4, and 6 mg·kg·d, ip) for 4 weeks to evaluate the anti-inflammation property of PL. Results Results indicated that PL inhibits CP progression by down regulating the expressions of TNF-α, IL-1β and ***, PL administration decelerated bone destruction in the rat with CP,evidenced by the aveolar bone loss(ABL) and H&E staining results. Conclusion With the given data, conclusion could be made that PL suppressed CP by down regulating the expressions of TNF-α, IL-1β and IL-6 and by inhibiting the bone loss.

关键词： Plumbagin chronic periodontitis tumor necrosis factor alpha interleukin 1β interleukin 6 bone loss

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大尺寸支承孔系同轴度激光测量系统及其精度分析

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应用激光 2008年第5期28卷 399-401,440页

作者：汪亭玉吕乃光江苏海事职业技术学院轮机工程系江苏南京211170 北京信息科技大学光电学院北京100085

本文对于大尺寸支承孔系同轴度的激光测量系统进行了说明与精度分析,给出了激光测量系统的结构和数学模型,讨论了各种系统误差和随机误差对于测量精度的影响,提出了测量系统的精度公式。分析结果表明,该方法的测量精度可以满足大尺寸直... 详细信息

本文对于大尺寸支承孔系同轴度的激光测量系统进行了说明与精度分析,给出了激光测量系统的结构和数学模型,讨论了各种系统误差和随机误差对于测量精度的影响,提出了测量系统的精度公式。分析结果表明,该方法的测量精度可以满足大尺寸直线性和同轴度测量的要求。

关键词：同轴度测量激光测量方法误差分析

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自闭症谱系障碍者抑制控制的影响因素及神经机制

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心理科学进展 2018年第8期26卷 1450-1464页

作者：孙岩房林王亭予崔丽辽宁师范大学心理学院大连116029 大连小海豚自闭症儿童康复中心大连116000

自闭症谱系障碍(ASD)是一种起源于儿童期的神经发育障碍,ASD的重复刻板行为与其抑制控制发展有密切关系。使用Go/No-go、Flanker及Stroop等范式的研究发现,ASD者抑制控制受损主要表现为反应抑制和干扰抑制能力存在缺陷;其主要影响因素... 详细信息

自闭症谱系障碍(ASD)是一种起源于儿童期的神经发育障碍,ASD的重复刻板行为与其抑制控制发展有密切关系。使用Go/No-go、Flanker及Stroop等范式的研究发现,ASD者抑制控制受损主要表现为反应抑制和干扰抑制能力存在缺陷;其主要影响因素是任务状态、被试年龄及取样;涉及的脑区和脑网络集中在前额皮层、前扣带回和基底神经节;涉及的基因集中在谷氨酸盐、γ-氨基丁酸与5-羟色胺三种神经递质。未来应从脑机制研究入手,综合考虑任务状态、个体特征对研究结果造成的影响,并着力开发更有效的干预模式。

关键词：自闭症谱系障碍抑制控制网络连接脑机制

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