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A Quantitative Seismic Topographic Effect Prediction Method Based upon BP Neural Network Algorithm and FEM Simulation

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Journal of Earth Science 2024年第4期35卷 1355-1366页

作者： Qifeng Jiang Mianshui Rong Wei Wei tingting chen Shandong Seismic Hazard Prevention Center Shandong Earthquake AgencyJinan250014China Shandong Institute of Earthquake Engineering Jinan250021China Key Laboratory of Urban Security and Disaster Engineering of China Ministry of Education Beijing University of TechnologyBeijing100124China Publicity and Education Center Shandong Earthquake AgencyJinan250014China Shandong Earthquake Station Shandong Earthquake AgencyJinan250014China

Topography can strongly affect ground motion,and studies of the quantification of hill surfaces’topographic effect are relatively *** this paper,a new quantitative seismic topographic effect prediction method based upon the BP neural network algorithm and three-dimensional finite element method(FEM)was *** FEM simulation results were compared with seismic records and the results show that the PGA and response spectra have a tendency to increase with increasing elevation,but the correlation between PGA amplification factors and slope is not obvious for low *** BP neural network models were established for the prediction of amplification factors of PGA and response *** kinds of input variables’combinations which are convenient to achieve are proposed in this paper for the prediction of amplification factors of PGA and response spectra,*** absolute values of prediction errors can be mostly within 0.1 for PGA amplification factors,and they can be mostly within 0.2 for response spectra’s amplification *** input variables’combination can achieve better prediction performance while the other one has better expandability of the predictive ***,the BP models only employ one hidden layer with about a hundred nodes,which makes it efficient for training.

关键词： seismic topographic effect finite element method BP neural network algorithm earthquake disaster prevention

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Enzyme-driven Nanorobots Walking Along Predesigned Tracks on the DNA Origami for Cargo Transport and Catalysis

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Chemical Research in Chinese Universities 2024年第2期40卷 333-342页

作者： NIE Cunpeng MA Tianran chen tingting CHU Xia State Key Laboratory of Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha410082P.R.China

In molecular engineering,designing and synthesizing molecular machines with capable of performing complex tasks,remains a formidable *** is an excellent candidate for building molecular robots because it is highly ***,we present an artificial nanorobot,in which a DNA cube serves as the inert‘body’,and nucleic acid catalysts based on an enzymatic nicking reaction act as the‘legs’for *** nanorobot can execute a series of actions,such as‘start’,‘turn’,and‘stop’when it walks along a predefined *** performance could be confirmed and monitored by using an atomic force microscope(AFM)and fluorescence *** by biological machines,we artificially designed a series of specialized tasks that combined walking with control of cargo transport and ***-time fluorescence kinetics curves provide monitoring signals for cargo transport and catalytic *** work can enrich the toolbox of DNA machinery and has great potential for engineering molecular nanofactories.

关键词： DNA origami DNA nanorobot Controlled cargo transport DNAzyme catalysis

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Burst-mode pulse generation in passively mode-locked all-fiber green/orange lasers at 543 nm and 602 nm

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Photonics Research 2024年第6期12卷 1231-1238页

作者： QIUJUN RUAN JINHAI ZOU CHUNNA FENG tingting chen HANG WANG ZHIPENG DONG ZHENGQIAN LUO Fujian Key Laboratory of Ultrafast Laser Technology and Applications School of Electronic Science and EngineeringXiamen UniversityXiamen 361005China Shenzhen Research Institution of Xiamen University Shenzhen 518000China

We report on the experimental realization of,to the best of our knowledge,the first green and orange passively mode-locked all-fiber *** mode-locking in the burst-pulse status is achieved at the wavelengths of 543.3 nm and 602.5 *** figure-9 cavity comprises the fiber end-facet mirror,gain fiber(Ho^(3+):ZBLAN fiber or Pr^(3+)/Yb^(3+):ZBLAN fiber),and fiber loop mirror(FLM).The FLM with long 460 HP fiber is not only used as an output mirror,but also acts as a nonlinear optical loop mirror for initiating visible-wavelength *** green/orange mode-locked fiber lasers with the fundamental repetition rates of 3.779/5.662 MHz produce long bursts containing ultrashort pulses with the 0.85/0.76 GHz intra-burst repetition rates,*** ultrashort intra-burst pulses stem from the dissipative four-wave-mixing effect in the highly nonlinear FLM as well as the intracavity Fabry–Perot *** bursts of 22.2/11.6 ns with ultrashort pulses of 87/62 ps are obtained in our *** visible-wavelength passively mode-locked lasers in an all-fiber configuration and burst-mode would represent an important step towards miniaturized ultrafast fiber lasers and may contribute to the applications in ablation-cooling micromachining,biomedicine imaging,and scientific research.

关键词： fiber passive pulse

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Magnesium fertilizer application increases peanut growth and pod yield under reduced nitrogen application in southern China

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The Crop Journal 2024年第3期12卷 915-926页

作者： Yu Gao Ruier Zeng Suzhe Yao Ying Wang Jianguo Wang Shubo Wan Wei Hu tingting chen Lei Zhang Guangdong Provincial Key Laboratory of Plant Molecular Breeding College of AgricultureSouth China Agricultural UniversityGuangzhou 510642GuangdongChina Shandong Academy of Agricultural Sciences Jinan 250100ShandongChina College of Agriculture Nanjing Agricultural UniversityNanjing 210095JiangsuChina

This study investigated the effect of magnesium application on peanut growth and yield under two nitrogen(N)application rates in acidic soil in southern *** chlorophyll content,net photosynthetic rate and dry matter accumulation of the N-sensitive cultivar decreased under reduced N treatments,whereas no effect was observed on the relevant indicators in the N-insensitive variety *** application increased the net photosynthetic rate by increasing the expression of genes involved in chlorophyll synthesis and Rubisco activity in the leaves during the pegging stage under 50%N treatment,while no effect on the net photosynthetic rate was observed under the 100%N *** rate of dry matter accumulation at the early growth stage,total dry matter accumulation and pod yield at harvest increased after Mg application under 50%N treatment by increasing the transportation of assimilates from stems and leaves to pods in both peanut varieties,whereas no effect was found under 100%N ***,Mg application increased the NUE under 50%N *** improvement of NUE in either peanut variety was found under 100%N treatment,while Mg application under the 50%N treatment can obtain a higher economic benefit than the 100%N *** acidic soil,application of 307.5 kg ha^(-1)of Mg sulfate fertilizer under 50%reduced nitrogen application is a suitable fertilizer management measure for improving carbon assimilation,NUE and achieve high peanut yields in southern China.

关键词： Peanut Magnesium Yield Reduced nitrogen application rate

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Potassium and calcium channels in different nerve cells act as therapeutic targets in neurological disorders

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Neural Regeneration Research 2025年第5期20卷 1258-1276页

作者： Qing Qiu Mengting Yang Danfeng Gong Haiying Liang tingting chen Department of Pharmacology School of PharmacyNantong UniversityNantongJiangsu ProvinceChina Jiangsu Province Key Laboratory of Inflammation and Molecular Drug Target NantongJiangsu ProvinceChina Department of Pharmacy Longyan First Affiliated Hospital of Fujian Medical UniversityLongyanFujian ProvinceChina

The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central nervous system, with sensory stimulation and excitation conduction functions. Astrocytes and microglia belong to the glial cell family, which is the main source of cytokines and represents the main defense system of the central nervous system. Nerve cells undergo neurotransmission or gliotransmission, which regulates neuronal activity via the ion channels, receptors, or transporters expressed on nerve cell membranes. Ion channels, composed of large transmembrane proteins, play crucial roles in maintaining nerve cell homeostasis. These channels are also important for control of the membrane potential and in the secretion of neurotransmitters. A variety of cellular functions and life activities, including functional regulation of the central nervous system, the generation and conduction of nerve excitation, the occurrence of receptor potential, heart pulsation, smooth muscle peristalsis, skeletal muscle contraction, and hormone secretion, are closely related to ion channels associated with passive transmembrane transport. Two types of ion channels in the central nervous system, potassium channels and calcium channels, are closely related to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. Accordingly, various drugs that can affect these ion channels have been explored deeply to provide new directions for the treatment of these neurological disorders. In this review, we focus on the functions of potassium and calcium ion channels in different nerve cells and their involvement in neurological disorders such as Parkinson's disease, Alzheimer's disease, depression, epilepsy, autism, and rare disorders. We also describe several clinical drugs that target potassium or calcium channels in nerve cells and could be u

关键词： astrocytes calcium channels central nervous system extracellular ion concentration microglia neurological disorders neurons potassium channels

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IL-6在肺动脉高压中的研究进展

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中国现代应用药学 2024年第10期41卷 1438-1446页

作者：陈婷婷杨进芦殿香青海大学医学院西宁810001 成都大学附属医院成都610086

白细胞介素-6(interleukin-6,IL-6)是一种多效性细胞因子,在炎症反应中起重要作用。越来越多的证据表明,IL-6在肺动脉高压的发生发展中也起到了十分重要的作用,肺动脉高压患者和动物模型的循环中IL-6水平明显升高,小鼠体内过表达IL-6可... 详细信息

白细胞介素-6(interleukin-6,IL-6)是一种多效性细胞因子,在炎症反应中起重要作用。越来越多的证据表明,IL-6在肺动脉高压的发生发展中也起到了十分重要的作用,肺动脉高压患者和动物模型的循环中IL-6水平明显升高,小鼠体内过表达IL-6可以诱导重度肺动脉高压,针对IL-6的治疗可以改善肺动脉高压。本文主要从分子水平对IL-6在肺动脉高压中的作用及其机制的研究进展进行综述,并对目前以IL-6为靶点治疗肺动脉高压的候选方案进行介绍,以期为肺动脉高压的临床药物研究开发提供参考。

关键词：白细胞介素-6 肺动脉高压肺动脉平滑肌细胞肺血管重塑作用机制

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建成环境影响公共健康的国内外比较研究及启示

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热带地理 2024年第4期44卷 569-582页

作者：李珊张林李建军陈婷婷陈锦棠广州大学建筑与城市规划学院广州510006 中山大学地理科学与规划学院//中国区域协调发展与乡村建设研究院广州510275

建成环境对公众身心健康产生复杂影响,揭示城市建成环境对公共健康的影响机制与作用路径,可为建成环境优化提供依据,降低环境污染、社会交往及体力活动缺失等引发的健康风险。西方研究起步较早,国内正处于探索阶段,通过对国内外相关研... 详细信息

建成环境对公众身心健康产生复杂影响,揭示城市建成环境对公共健康的影响机制与作用路径,可为建成环境优化提供依据,降低环境污染、社会交往及体力活动缺失等引发的健康风险。西方研究起步较早,国内正处于探索阶段,通过对国内外相关研究进行比较,有助于厘清该领域研究的发展脉络,找出共同问题与特征,把握国内研究的提升方向。因此,文章基于WOS、CNKI数据库,筛选2000—2022年城乡规划、地理科学、健康医学、环境心理学等领域关于建成环境影响公共健康的658篇中英文献,借助Citespace软件对其理论脉络、研究内容及前沿趋势等进行计量分析与梳理。研究发现,中西方学界在理论创新、关注群体与研究内容等方面存在差异。具体地,国际研究率先提出社会福利与环境公正等理论视角,并在理论指导下挖掘建成环境对公共健康在多元群体的影响机制;而国内研究在理论创新上相对不足,侧重引入西方理论在中国展开实证应用,多关注其对老年群体与女性群体影响的传导路径,且实证以静态研究为主,缺乏动态性。

关键词：建成环境公共健康健康地理城市规划比较研究

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鼻中隔偏曲矫正术手术室护理配合

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中国医学文摘（耳鼻咽喉科学） 2024年第2期39卷 152-154页

作者：陈庭庭合肥市第二人民医院安徽合肥230000

目的探究鼻中隔偏曲矫正术手术室护理配合方法及效果。方法将98例于2021年4月-2022年4月在本院行鼻中隔偏曲矫正术的患者设为研究对象,随机分为参照组(n=49;常规手术室护理)、试验组(n=49;手术室护理配合),对比护理效果。结果与参照组相... 详细信息

目的探究鼻中隔偏曲矫正术手术室护理配合方法及效果。方法将98例于2021年4月-2022年4月在本院行鼻中隔偏曲矫正术的患者设为研究对象,随机分为参照组(n=49;常规手术室护理)、试验组(n=49;手术室护理配合),对比护理效果。结果与参照组相比,试验组手术时间、术中出血量、住院时间明显更短,P<0.05;护理满意度明显更高,P<0.05。结论在鼻中隔偏曲矫正术中加强手术室护理配合能够取得显著的临床护理效果,可加快手术进程,减少术中出血量,加快患者出院与康复时间,提高护理满意度。

关键词：耳鼻咽喉鼻中隔偏曲矫正术手术室护理

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汕头市2020—2022年臭氧污染特征及大气环流客观分型

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环境监控与预警 2024年第3期16卷 72-78页

作者：陈婷婷广东省汕头生态环境监测中心站广东汕头515000

利用2020—2022年汕头市环境空气自动监测站数据和气象数据,分析汕头市出现污染天气过程中臭氧污染的变化特征。采用自组织神经网络(self-organizing feature mapping, SOM模型)智能天气分型算法对汕头市2020—2022年的天气形势的再分... 详细信息

利用2020—2022年汕头市环境空气自动监测站数据和气象数据,分析汕头市出现污染天气过程中臭氧污染的变化特征。采用自组织神经网络(self-organizing feature mapping, SOM模型)智能天气分型算法对汕头市2020—2022年的天气形势的再分析资料进行客观分型,总结出汕头市容易出现臭氧污染的天气环流分型,分别为东海气旋低压槽型(秋季)、高压后部与南海低压型(春季)、弱高压底部型(秋季)、槽后脊前型(春季)和副高控制型(秋季)。对应的臭氧污染站次分别为125站次(16%),120站次(15%),115站次(14%),101站次(13%)和78站次(10%)。汕头市春、秋季较易发生臭氧污染,从近3年(2020—2022年)气团传输轨迹来看,臭氧污染的主要气团来源为东北沿海、西南沿海以及偏北内陆。

关键词：客观天气分型臭氧污染环流类型自组织神经网络模型

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开放教育课程思政建设路径分析

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贵州开放大学学报 2024年第2期32卷 1-6页

作者：陈婷婷贵州开放大学贵阳550004

开放教育课程思政关乎开放教育人才培养质量。目前,开放教育课程思政的理论与实践正在积极互动,努力开创开放教育课程思政的新局面。文章分析了开放教育课程思政建设中的存在问题,如理论体系不健全、建设意识不强烈、协同发展不深入、... 详细信息

开放教育课程思政关乎开放教育人才培养质量。目前,开放教育课程思政的理论与实践正在积极互动,努力开创开放教育课程思政的新局面。文章分析了开放教育课程思政建设中的存在问题,如理论体系不健全、建设意识不强烈、协同发展不深入、教学实践不生动等,意在通过分析其在推进中的掣肘问题,提出相应的解决对策,以期提高开放教育课程思政育人效果。

关键词：课程思政开放教育路径

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