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Chinese Medical Journal 2024年第4期137卷 499-501页

作者： Xia Xu Yanni Guo tingting liao Huale Zhang Rumeng Jiang Shuyao Huang Jianying Yan Department of Obstetrics and Gynecology Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics&Gynecology and PediatricsFujian Medical UniversityFuzhouFujian 350001China

To the Editor:Gestational diabetes mellitus(GDM)is a pathologic condition in which glucose intolerance and insulin resistance develop to different degrees during *** with GDM have higher odds of adverse maternal and fetal *** with a history of GDM were at a significantly increased risk for recurrence of GDM in subsequent *** previous and some other studies found an increased incidence of adverse perinatal outcomes in pregnant with recurrent GDM.^([1])So far,women with a prior history of GDM are not recommended to refrain from subsequent pregnancy in light of the limited available *** about those women with a history of recurrent GDM?Should women with recurrent GDM be recommended to avoid further pregnancy?Currently,studies on perinatal outcomes of women with re-recurrent GDM and their prognostic factors are very ***,this retrospective cohort study was performed to explore perinatal outcomes of pregnant woman with re-recurrent GDM and their prognostic factors.

关键词： mellitus pregnancy diabetes

Process analysis of characteristics of the boundary layer during a heavy haze pollution episode in an inland megacity,China

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Journal of Environmental Sciences 2016年第2期28卷 138-144页

作者： Shan Wang tingting liao Lili Wang Yang Sun Xi'an Meteorological Bureau Xi'an 710016 China Plateau Atmospheric and Environment Key Laboratory of Sichuan Province College of Atmosphere Sciences Chengdu University of Information Technology Chengdu 610225 China State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry (LAPC) Institute of Atmospheric PhysicsChinese Academy of Sciences Beijing 100191 China

Ground observation data from 8 meteorological stations in Xi＇an, air mass concentration data from 13 environmental quality monitoring sites in Xi＇an, as well as radiosonde observation and wind profile radar data, were used in this study. Thereby, the process,causes and boundary layer meteorological characteristics of a heavy haze episode occurring from 16 to 25 December 2013 in Xi＇an were analyzed. Principal component analysis showed that this haze pollution was mainly caused by the high-intensity emission and formation of gaseous pollutants（NO_2, CO and SO_2） and atmospheric particles（PM_（2.5）（fine particles） and PM10（respirable suspended particle）. The second cause was the relative humidity and continuous low temperature. The third cause was the allocation of the surface pressure field. The presence of a near-surface temperature inversion at the boundary layer formed favorable stratification conditions for the formation and maintenance of heavy haze pollution. The persistent thick haze layer weakened the solar radiation. Meanwhile, a warming effect in the urban canopy layer and in the transition zone from the urban friction sublayer to the urban canopy was indicated. All these conditions facilitated the maintenance and reinforcement of temperature inversion. The stable atmospheric stratification finally acted on the wind field in the boundary layer, and further weakened the exchange capacity of vertical turbulence. The superposition of a wind field with the horizontal gentle wind induced the typical air stagnation and finally caused the deterioration of air quality during this haze event.

关键词： Haze Temperature inversion Radiation Air stagnancy

中国高校国际科技合作的战略布局与管理创新分析

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科技智囊 2024年第7期 71-76页

作者：廖婷婷孙燕琨王诗忠中山大学广东广州510275

[研究目的]高校是科技、人才和创新的重要结合点,是国际科技交流合作的重要阵地,对其进行分析具有重要现实意义。[研究方法]从科研管理视角出发,基于北京大学、浙江大学、上海交通大学、清华大学、复旦大学五所国际化合作水平较高的国... 详细信息

[研究目的]高校是科技、人才和创新的重要结合点,是国际科技交流合作的重要阵地,对其进行分析具有重要现实意义。[研究方法]从科研管理视角出发,基于北京大学、浙江大学、上海交通大学、清华大学、复旦大学五所国际化合作水平较高的国内高等学府关于国际科技合作的战略布局与管理创新,从战略规划、体制机制、专项基金、人才队伍等角度总结了国内高校为推进国际科技合作采取的一系列创新举措及取得的成功经验,并根据校级国际科技合作工作开展过程中暴露出的部分问题进行了思考。[研究结论]对此,提出国内高校深化国际科技合作的建议:加强顶层设计和统筹谋划、转变合作思路开拓新赛道、组织实际举措确保战略落地。

关键词：国际科技合作开放创新科技合作科研管理

数字乳腺X线断层摄影定位与二维立体定位下乳腺病变不同活检方式的比较研究

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中华放射学杂志 2024年第9期58卷 916-922页

作者：杨玉婷廖婷婷林小慧欧阳汝珊李霖赖小慧戴懿马捷暨南大学第二临床医学院深圳518020 深圳市人民医院放射科深圳518020 中山大学第八附属医院放射科深圳528406 深圳市罗湖区人民医院放射科深圳518000 北京大学深圳医院放射科深圳518036

目的比较数字乳腺X线断层摄影(DBT)定位与立体定位下乳腺病变穿刺活检的临床应用价值。方法该研究为横断面研究。回顾性分析2021年8月至2023年10月在深圳市人民医院、深圳市罗湖区人民医院及北京大学深圳医院接受乳腺活检的患者250例,其... 详细信息

目的比较数字乳腺X线断层摄影(DBT)定位与立体定位下乳腺病变穿刺活检的临床应用价值。方法该研究为横断面研究。回顾性分析2021年8月至2023年10月在深圳市人民医院、深圳市罗湖区人民医院及北京大学深圳医院接受乳腺活检的患者250例,其中DBT定位下活检136例(DBT定位组)、立体定位下活检114例(立体定位组)。立体定位组穿刺活检方法包括核芯针穿刺活检(CNB)和金属丝定位,DBT定位组穿刺活检方法包括CNB、金属丝定位、真空辅助乳腺活检(VABB)。采用χ2检验或Mann-Whitney U检验比较2组不同活检方法的穿刺成功率、操作时间、定位时间、穿刺时间、获得首张有效定位相的次数、曝光次数、并发症情况。结果金属丝定位活检中,DBT定位组穿刺成功率为100%(33/33),立体定位组穿刺成功率为96%(48/50),二者差异无统计学意义(P=0.515);与立体定位组比较,DBT定位组操作时间、定位时间更短,获得首张有效定位相的次数、曝光次数更少(P<0.05);DBT定位组与立体定位组并发症发生率均较低,差异无统计学意义(P=0.871)。CNB中,DBT定位组与立体定位组穿刺成功率均较高,差异无统计学意义(P=0.080);与立体定位组比较,DBT定位组操作时间、定位时间、穿刺时间短,获得首张有效定位相的次数、曝光次数少,二者差异具有统计学意义(P<0.05);DBT定位组与立体定位组并发症发生率均较低,差异无统计学意义(P=0.627)。21例接受DBT下VABB,操作时间为(19.90±3.38)min,定位时间为6.00(6.00,7.00)min,穿刺时间为(13.42±3.28)min,获得首张有效定位相次数为1.00(1.00,1.00)次,曝光次数4.00(3.50,5.00)次,1例穿刺后出现剧烈疼痛。结论与立体定位活检比较,DBT定位活检可减少操作时间及曝光次数,且能针对更多乳腺病变类型,临床应用价值更高。

关键词：乳腺肿瘤活组织检查 X线断层定位立体定位

基于YOLOv3的袋式除尘器滤袋破损自动检测方法

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烧结球团 2024年第1期49卷 99-105页

作者：李旭东廖婷婷乐文毅曾小信陈思墨李宗平中冶长天国际工程有限责任公司工程技术研究中心湖南长沙410205 中冶长天国际工程有限责任公司国家烧结球团装备系统工程技术研究中心湖南长沙410205

干式除尘装置中袋式除尘器的滤袋在长时间使用后会出现破损,造成能源消耗增加、除尘效率降低、污染环境等严重问题。为此,本文采用在除尘舱室处搭建粉尘烟雾检测摄像头,并基于YOLOv3算法检测袋口烟雾的泄漏情况。试验检测步骤:①根据真... 详细信息

干式除尘装置中袋式除尘器的滤袋在长时间使用后会出现破损,造成能源消耗增加、除尘效率降低、污染环境等严重问题。为此,本文采用在除尘舱室处搭建粉尘烟雾检测摄像头,并基于YOLOv3算法检测袋口烟雾的泄漏情况。试验检测步骤:①根据真实除尘舱室尺寸设计袋式除尘器袋口烟雾泄漏实验室平台,采集不同洞口烟雾泄漏的图像数据;②使用软件标注这些图像数据;③搭建Darknet深度学习框架,采用YOLOv3算法对图像数据进行训练,并依据模型计算结果识别破袋情况。结果表明:模型对于批量图像的识别准确率能达到91%以上,对于连续视频的识别准确率可达95.65%。本文系统可以减少除尘器运行中的人工检测,降低工厂人力资源成本和工人劳动强度,可以避免生产中的安全隐患和损失,可以为工厂的生产安全及定期维护提供技术指导,也为全厂智能化生产提供了有效的方案。

关键词：烟气除尘布袋除尘器机器学习图片识别 YOLOv3

Ferrous Oxide Nanoparticles Induced Abnormal Cardiac Development in Zebrafish Through Hypoxia and Ferroptosis

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Chemical Research in Chinese Universities 2023年第3期39卷 502-507页

作者： ZHENG Naying CHEN Xintan ZHAN Ruyu liao tingting SHI Yiyue SUN Xiaolian CHEN Shuzhen ZUO Zhenghong State Key Laboratory of Cellular Stress Biology Xiang’an Hospital of Xiamen UniversitySchool of Life SciencesFaculty of Medicine and Life SciencesXiamen UniversityXiamen361102China Department of Microbiology and Immunology Fujian Provincial Key Laboratory of Functional and Clinical Translational MedicineXiamen Key Laboratory of Respiratory DiseasesXiamen Medical CollegeXiamen361023China Chest Pain Center Anxi County HospitalQuanzhou362400China State Key Laboratory of Natural Medicines Key Laboratory of Drug Quality Control and PharmacovigilanceDepartment of Pharmaceutical AnalysisChina Pharmaceutical UniversityNanjing210009China

Ferrous oxide nanoparticles(nFeO)have potential applications in biomedicine,industrial processes,and waste water ***,the biocompatibility of nFeO remains *** this study,we synthesized rhombus-shaped nFeO and exposed them to zebrafish embryos to investigate the bio-safety of *** results showed that exposure to nFeO led to pericardial edema,heart bleeding,and enlarged ***,the content of dissolved oxygen ***^(2+)ions,which were released from the core of nFeO,were oxidized into Fe^(3+).This caused the overexpression of tfa and fpn genes,which carried Fe^(3+)into and out of the cell membrane,*** overload of Fe^(3+)caused ferroptosis in zebrafish larvae,which was evidenced by the overexpression of the marker gene ptgs2 and the marker production malondialdehyde(MDA)of ***,neither the ferrostatin-1(Fer-1)inhibitor nor deferoxiamine(DFO)could completely rescue the toxicity caused by *** found that co-treatment of nFeO with CaO_(2),a dissolved oxygen donor,and Fer-1 or DFO could totally rescue pericardial edema and heart *** results provide new knowledge that both hypoxia and ferroptosis play important roles in nFeO-induced zebrafish cardiac developmental toxicity,which is beneficial for the development and safe application of iron-based nanomaterials in the future.

关键词： Nanoparticle Biocompatibility Heart Zebrafish Iron

李世杰教授中医药治疗大肠癌患者术后腹泻临床思路探讨

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国际医药卫生导报 2024年第9期30卷 1422-1425页

作者：刘欢廖婷婷张政委李世杰成都中医药大学附属医院肿瘤一科成都610000

大肠癌是常见的消化道恶性肿瘤之一,腹泻是大肠癌患者术后常见并发症之一。李世杰教授长期从事中西医结合治疗恶性肿瘤工作,尤其对中医药治疗恶性肿瘤及其并发症等工作有独到见解。本文阐述了李世杰教授中医药治疗大肠癌患者术后腹泻临... 详细信息

大肠癌是常见的消化道恶性肿瘤之一,腹泻是大肠癌患者术后常见并发症之一。李世杰教授长期从事中西医结合治疗恶性肿瘤工作,尤其对中医药治疗恶性肿瘤及其并发症等工作有独到见解。本文阐述了李世杰教授中医药治疗大肠癌患者术后腹泻临床思路。他从癌症发生发展的一般规律出发,以正虚邪实致病为基本理论,总结出大肠癌患者术后腹泻的基本病机是脾气亏虚,脾虚湿盛是大肠癌术后腹泻的重要因素,并提出治疗大肠癌患者术后腹泻时应遵循“衷中参西,病证结合、扶正祛邪,益气健脾为基石、分期论治,凭证择方”的论治原则。

关键词：大肠癌术后腹泻中医药名医经验李世杰

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慢性心力衰竭患者厌食症现状及其影响因素

广西医学 2024年第6期46卷 839-846页

作者：李高叶杨丽廖婷婷刘玲芳甘露广西医科大学第一附属医院心血管内科广西南宁市530021 广西医科大学第一附属医院护理部广西南宁市530021

目的调查慢性心力衰竭患者厌食症现状及其影响因素。方法采用便利抽样法,选取160例慢性心力衰竭患者,使用临床资料调查问卷、中文版厌食症恶病质治疗功能性评估‑厌食恶病质分量表、匹兹堡睡眠质量指数(PSQI)量表、医院焦虑抑郁量表对其... 详细信息

目的调查慢性心力衰竭患者厌食症现状及其影响因素。方法采用便利抽样法,选取160例慢性心力衰竭患者,使用临床资料调查问卷、中文版厌食症恶病质治疗功能性评估‑厌食恶病质分量表、匹兹堡睡眠质量指数(PSQI)量表、医院焦虑抑郁量表对其进行调查,采用多因素Logistic回归模型分析影响慢性心力衰竭患者厌食症发生的因素。结果160例慢性心力衰竭患者中,厌食症发生率为50.63%(81/160)。多因素Logistic回归分析结果显示,家庭人均月收入、美国纽约心脏病学会(NYHA)心功能分级、合并消化系统疾病情况、红细胞计数、血钾水平、PSQI量表总分是慢性心力衰竭患者发生厌食症的影响因素(P<0.05)。结论慢性心力衰竭患者厌食症发生率较高,家庭人均月收入、NYHA心功能分级、合并消化系统疾病情况、红细胞计数、血钾水平、睡眠质量是慢性心力衰竭患者发生厌食症的影响因素。

关键词：慢性心力衰竭厌食症影响因素

Clinical Characteristics and Outcomes of Severe or Critical COVID-19 Patients Presenting No Respiratory Symptoms or Fever at Onset

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Engineering 2021年第10期7卷 1452-1458页

作者： Juanjuan Xu Zhengrong Yin Yu Liu Sufei Wang Limin Duan Yi An Jinshuo Fan tingting liao Yang Jin Jianguo Chen Department of Respiratory and Critical Care Medicine NHC Key Laboratory of Pulmonary DiseasesUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Physical Examination Center Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Anesthesiology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Pharmacology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

It is difficult to identify suspected cases of atypical patients with coronavirus disease 2019(COVID-19),and data on severe or critical patients are *** retrospective study presents the clinical,laboratory,and radiological profiles,treatments,and outcomes of atypical COVID-19 patients without respiratory symptoms or fever at *** study examined ten atypical patients out of 909 severe or critical patients diagnosed with COVID-19 in Wuhan Union Hospital West Campus between 25 January 2020 and 10 February *** were obtained from the electronic medical records of severe or critical patients without respiratory symptoms or fever at *** were followed up to discharge or *** 943 COVID-19 patients,909(96.4%)were severe or critical *** the severe or critical patients,ten(1.1%)presented without respiratory symptoms or fever at *** median age of the ten participants was 63 years(interquartile range(IQR):57–72),and seven participants were *** median time from symptom onset to admission was 14 d(IQR:7–20).Eight of the ten patients had chronic *** patients had fatigue(n=5),headache or dizziness(n=4),diarrhea(n=5),anorexia(n=3),nausea or vomiting(n=3),and eye discomfort(n=1).Four patients were found to have *** examination revealed that nine patients had bilateral pneumonia and one had unilateral ***,two patients died and eight were *** the discharged patients,the median time from admission to discharge lasted 24 d(IQR:13–43).In summary,some severe or critical COVID-19 patients were found to have no respiratory symptoms or fever at *** such atypical cases should be identified and quarantined as early as possible,since they tend to have a prolonged hospital stay or fatal *** computed tomography(CT)scan and nucleic acid detection should be performed immediately on close contacts of COVID-19 patients to screen out those with atypical infections,even if the contac

关键词： SARS-CoV-2 COVID-19 Atypical clinical characteristics

Facile synthesis of nanoparticles-stacked Co_(3)O_(4)nanoflakes with catalase-like activity for accelerating wound healing

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Regenerative Biomaterials 2024年第3期3卷 82-91页

作者： Yanan Huang Wanyi liao Wenxuan Wang tingting Zhang Yan Zhang Lei Lu school and Hospital of Stomatology Wenzhou Medical UniversityWenzhou 325027China sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs School of Life Science and EngineeringSouthwest jiaotong UniversityChengdu 610031China Key Lab of Advanced Technology of Materials of Education Ministry School of Materials Science and EngineeringSouthwest jiaotong UniversityChengdu 610031China school of Chemistry Southwest Jiaotong UniversityChengduSichuan 610031China

Delayed wound healing caused by excessive reactive oxygen species(Ros)remains a considerable *** recent years,metal oxide nanozymes have gained significant attention in biomedical ***,a comprehensive investigation of Co_(3)O_(4)-based nanozymes for enhancing wound healing and tissue regeneration is *** study focuses on developing a facile synthesis method to produce high-stability and costeffective Co_(3)O_(4)nanoflakes(NFs)with promising catalase(CAT)-like activity to regulate the oxidative microenvironment and accelerate wound *** closely arranged Co_(3)O_(4)nanoparticles(NPs)within the NFs structure result in a significantly larger surface area,thereby amplifying the enzymatic activity compared to commercially available Co_(3)O_(4)*** physiological conditions,itwas observed that CogO,NFs efficientlybreak down hydrogen peroxide(H_(2)O_(2))without generating harmful radicals(OH).Moreover,they exhibit excellent compatibility with various cells involved in wound healing,promoting fibroblast growth and protecting cells from oxidatives *** a ratmodel,Co_(3)O_(4) NFs facilitate both the hemostatic and proliferative phases of wound healing,consequently accelerating the ***,thepromising results of Co_(3)O_(4)NFs highlight their potential in promoting wound healing and tissue regeneration.

关键词： Co_(3)O_(4) nanoflake nanozyxygen species wound healing