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眼周轮匝肌联合皱眉肌、降眉肌及额肌注射A型肉毒毒素治疗良性特发性眼睑痉挛的疗效观察

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中华眼科医学杂志（电子版） 2017年第4期7卷 165-170页

作者：李婷银丽新疆维吾尔自治区人民医院眼科 830001 新疆乌鲁木齐市普瑞眼科医院眼整形及泪道科 830000

目的探讨眼周轮匝肌联合皱眉肌、降眉肌及额肌注射A型肉毒毒素治疗良性特发性眼睑痉挛的疗效。方法收集2.16年6月至12.于新疆维吾尔自治区人民医院诊断为中重度良性特发性眼睑痉挛的患者40例(80只眼)的临床资料。将全部病例分为观察组... 详细信息

目的探讨眼周轮匝肌联合皱眉肌、降眉肌及额肌注射A型肉毒毒素治疗良性特发性眼睑痉挛的疗效。方法收集2.16年6月至12.于新疆维吾尔自治区人民医院诊断为中重度良性特发性眼睑痉挛的患者40例(80只眼)的临床资料。将全部病例分为观察组和对照组两组。其中,观察组为2.例(40只眼),采用A型肉毒毒素局部注射治疗,注射点为眼周轮匝肌;对照组为2.例(40只眼),采用A型肉毒毒素局部注射治疗,注射点为眼周轮匝肌、皱眉肌、降眉肌及额肌。注射治疗结束后,对治疗疗效进行评估。疗效评价指标分为完全缓解、显著缓解、部分缓解及无缓解四项。依据面部皱纹的评分法对皱纹进行量化评分,0分无皱纹、1分为轻度皱纹、2.为中度皱纹、3分为中重度皱纹及4分为重度皱纹。两组A型肉毒毒素用量的比较采用t检验。治疗效果和面部皱纹评分的比较采用Kruskal-Wallis H秩和检验。上睑下垂程度的组间比较采用卡方检验。结果观察组A型肉毒毒素的用量为(40.0±2.5)U,对照组A型肉毒毒素的用量为(32.0±2.5)U,二者比较差异有统计学意义(t=10.12.P2.%及2.%;对照组分别为75%、2.%及5%,两组效果评价经Kruskal-Wallis H秩和检验,差异无统计学意义(Hc=-1.18,P>0.05)。观察组出现不同程度上睑下垂3例,对照组出现1例,二者差异无统计学意义(χ~2.-1.18,P>0.05);观察组和对照组术后面部动力性皱纹评分比较,对照组评分要高于观察组,二者差异具有统计学意义(Hc=-5.49,P<0.05)。结论与选择在眼周轮匝肌单独注射A型肉毒毒素相比,选择在眼周轮匝肌联合皱眉肌、降眉肌及额肌注射A型肉毒毒素的方法治疗特发性眼睑痉挛更加有效。

关键词：良性特发性眼睑痉挛 A型肉毒毒素注射位点局部注射

混流式核主泵内流动结构与压力脉动特性关联分析

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工程热物理学报 2017年第8期38卷 1676-1682页

作者：倪丹杨敏官高波李忠李玉婷陆胜江苏大学能源与动力工程学院镇江212013 江苏海狮泵业制造有限公司靖江214500

核主泵内的流动不稳定将会引起严重振动,不利于其安全稳定运行。因此本文基于大涡模拟(LES)数值计算方法对几个典型工况下核主泵内部非稳态流动结构及其压力脉动特性进行全面阐述与关联性分析。研究表明,随着流量的增加,动静干涉作用在... 详细信息

核主泵内的流动不稳定将会引起严重振动,不利于其安全稳定运行。因此本文基于大涡模拟(LES)数值计算方法对几个典型工况下核主泵内部非稳态流动结构及其压力脉动特性进行全面阐述与关联性分析。研究表明,随着流量的增加,动静干涉作用在导叶出口处逐渐增加;偏工况条件下,导叶出口处压力脉动频谱低频段中均出现复杂激励频率,尤其是靠近出液管附近的导叶出口处。核主泵在偏大流量工况下运行时壳体右侧内部非稳态流动结构相较于壳体左侧更加复杂;在偏小流量工况下运行时壳体底部压力脉动更加剧烈。本文进一步详细描述了核主泵球形壳体内强涡量区的流动结构及其成因,并且发现测点处的压力频谱与涡量频谱有相同的主要激励频率,因此证明核主泵内非定常旋涡流动结构是激励压力脉动的主因之一。

关键词：核主泵压力脉动非定常大涡模拟

Character Sheaves for Classical Graded Lie Algebras

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Acta Mathematica Sinica,English Series 2024年第3期40卷 870-884页

作者： ting XUE School of Mathematics and Statistics University of MelbourneVIC 3010Australia Department of Mathematics and Statistics University of HelsinkiHelsinki 00014Finland

In this note we study character sheaves for graded Lie algebras arising from inner automorphisms of special linear groups and Vinberg’s type Ⅱ classical graded Lie algebras.

关键词： Graded Lie algebras character sheaves Fourier transform nilpotent orbits

Molecular Chaperone-Dependent Polymer Translocation through Nanopores: The Effects of Chaperone Concentration and Chaperone-Polymer Interaction

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Chinese Journal of Polymer Science 2024年第1期42卷 125-132,I0011页

作者： Chang-Sheng Zuo Kang Wang Li-Zhen Sun ting-ting Sun Department of Physics Zhejiang University of Science and TechnologyHangzhou 310023China Department of Applied Physics Zhejiang University of TechnologyHangzhou 310014China

The polymer translocation through a nanopore from a donor space(or named cis side) to a receiver space(trans side) in the chaperone-induced crowded environment has attracted increasing attention in recent years due to its significance in biological systems and technological applications. In this work, we mainly focus on the effects of chaperone concentration and chaperone-polymer interaction on the polymer translocation. By assuming the polymer translocation to be a quasi-equilibrium process, the free energy F of the polymer can be estimated by Rosenbluth-Rosenbluth method and then the translocation time τ can be calculated by Fokker-Plank equation based on the obtained free energy landscape. Our calculation results show that the translocation time can be controlled by independently tuning the chaperone concentration and chaperone-polymer interaction at the cis side or the trans side. There exists a critical chaperone-polymer attraction ε~*=-0.2.at which the volume exclusion and interaction effects of the chaperone can balance each other. Additionally, we also find that at large chaperone-polymer attraction, the translocation time is mainly governed by the diffusion coefficient of the polymer.

关键词： Polymer translocation Rosenbluth-Rosenbluth method Fokker-Plank equation Free energy landscapes

Isotopic dependence of the yield ratios of light fragments from different projectiles and their unified neutron skin thicknesses

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Nuclear Science and Techniques 2024年第3期35卷 228-236页

作者： ting-Zhi Yan Shan Li School of Energy and Power Engineering Northeast Electric Power UniversityJilin 132012China

The yield ratios of neutron-proton(R(n/p))and^(3)H-^(3)He(R(^(3)H∕^(3)He))with reduced rapidity from 0 to 0.5 were simulated at 50 MeV/u even-even ^(36−56)Ca+^(40)Ca,even-even ^(48−78)Ni+^(58)Ni,and ^(100−139)Sn(every third isotopes)+112.Sn for full reduced impact parameters using the isospin-dependent quantum molecular dynamics(IQMD)*** neutron and proton density distributions and root-mean-square radii of the reaction systems were obtained using the Skyrme-Hartree-Fock model,which was used for the phase space initialization of the projectile and target in *** defined the unified neutron skin thickness asΔRnp=2.>^(1∕2. n−2.>^(1∕2.p,which was negative for neutron-deficient *** unifiedΔRnp values for nuclei with the same relative neutron excess from different isotopic chains were nearly equal,except for extreme neutron-rich isotopes,which is a type of scaling *** yield ratios of the three isotopic chain-induced reactions,which depended on the reduced impact parameter and unified neutron skin thickness,were *** results showed that both R(n/p)and R(^(3)H∕^(3)He)decreased with a reduced impact parameter for extreme neutron-deficient isotopes;however,they increased with reduced impact parameters for extreme neutron-rich isotopes,and increased with theΔRnp of the projectiles for all reduced impact *** addition,a scaling phenomenon was observed betweenΔR np and the yield ratios in peripheral colli-sions from different isotopic chain projectiles(except for extreme neutron-rich isotopes).Thus,R(n/p)and R(^(3)H∕^(3)He)from peripheral collisions were suggested as experimental probes for extracting the neutron or proton skin thicknesses of non-extreme neutron-rich nuclei from different isotopic chains.

关键词： Exotic nuclei Unified neutron skin thickness Yield ratios IQMD

三峡水库运行对长江荆南三口生态系统健康的影响

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湖南师范大学自然科学学报 2016年第6期39卷 15-19,54页

作者：李景保李雅婷蒋文杰湖南师范大学资源与环境科学学院中国长沙410081 同济大学环境科学与工程学院中国上海200092 黔阳一中中国怀化418200

根据荆南三口河系五个代表性水文监测站1981—2.15年的水文资料,运用层次分析法对水沙、水质和生物多样性3个方面的7个指标建立指标体系,并得出权重.根据评价标准对每个指标进行评分,加权相加得到总分值对三峡水库影响下的荆南三口河系... 详细信息

根据荆南三口河系五个代表性水文监测站1981—2.15年的水文资料,运用层次分析法对水沙、水质和生物多样性3个方面的7个指标建立指标体系,并得出权重.根据评价标准对每个指标进行评分,加权相加得到总分值对三峡水库影响下的荆南三口河系生态系统健康程度进行综合评价.结果表明:(1)河流生态系统健康状态与水沙特性息息相关,因此三峡水库对荆南三口河流生态系统健康的影响主要体现在水沙、水温、水质和生物多样性等方面;(2.三峡水库运行前荆南三口河流生态系统健康程度为"健康"程度,且各个指标都基本达到健康河流标准;(3)三峡水库运行后荆南三口河流生态系统健康程度为"亚健康"程度,相较于三峡水库运行前,各指标的分值下降较大.研究三峡水库对三口河流生态系统健康影响,对优化三峡水库调度方案和维护荆南三口河系生态健康具有重要的意义.

关键词：河流生态系统荆南三口河系健康评价层次分析法

Predictability of the upper ocean heat content in a Community Earth System Model ensemble prediction system

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Acta Oceanologica Sinica 2024年第1期43卷 1-10页

作者： ting Liu Wenxiu Zhong State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China School of Atmospheric Sciences Sun Yat-Sen UniversityZhuhai 519082China

Upper ocean heat content(OHC)has been widely recognized as a crucial precursor to high-impact climate variability,especially for that being indispensable to the long-term memory of the *** the predictability of OHC using state-of-the-art climate models is invaluable for improving and advancing climate *** developed retrospective forecast experiments,based on a Community Earth System Model ensemble prediction system,offer a great opportunity to comprehensively explore OHC *** results indicate that the skill of actual OHC predictions varies across different oceans and diminishes as the lead time of prediction *** spatial distribution of the actual prediction skill closely resembles the corresponding persistence skill,indicating that the persistence of OHC serves as the primary predictive signal for its *** decline in actual prediction skill is more pronounced in the Indian and Atlantic oceans than in the Pacific Ocean,particularly within tropical ***,notable seasonal variations in the actual prediction skills across different oceans align well with the phase-locking features of OHC *** potential predictability of OHC generally surpasses the actual prediction skill at all lead times,highlighting significant room for improvement in current OHC predictions,especially for the North Indian Ocean and the Atlantic *** such improvements necessitates a collaborative effort to enhance the quality of ocean observations,develop effective data assimilation methods,and reduce model bias.

关键词： ocean heat content prediction skill retrospective forecast experiment

The Role of Underlying Boundary Forcing in Shaping the Recent Decadal Change of Persistent Anomalous Activity over the Ural Mountains

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Advances in Atmospheric Sciences 2024年第8期41卷 1496-1510,1661-1667页

作者： ting LEI Shuanglin LI Climate Change Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Beijing Meteorological Service Center Beijing 100089China University of Chinese Academy of Sciences Beijing 100049China Department of Atmospheric Science China University of GeosciencesWuhan 430074China

Observational analyses demonstrate that the Ural persistent positive height anomaly event(PAE) experienced a decadal increase around the year 2.00, exhibiting a southward displacement afterward. These decadal variations are related to a large-scale circulation shift over the Eurasian Continent. The effects of underlying sea ice and sea surface temperature(SST) anomalies on the Ural PAE and the related atmospheric circulation were explored by Atmospheric Model Intercomparison Project(AMIP) experiments from the Coupled Model Intercomparison Project Phase 6 and by sensitivity experiments using the Atmospheric General Circulation Model(AGCM). The AMIP experiment results suggest that the underlying sea ice and SST anomalies play important roles. The individual contributions of sea ice loss in the Barents-Kara Seas and the SST anomalies linked to the phase transition of the Pacific Decadal Oscillation(PDO) and Atlantic Multidecadal Oscillation(AMO) are further investigated by AGCM sensitivity experiments isolating the respective *** sea ice decline in Barents-Kara Seas triggers an atmospheric wave train over the Eurasian mid-to-high latitudes with positive anomalies over the Urals, favoring the occurrence of Ural PAEs. The shift in the PDO to its negative phase triggers a wave train propagating downstream from the North Pacific. One positive anomaly lobe of the wave train is located over the Ural Mountains and increases the PAE there. The negative-to-positive transition of the AMO phase since the late-1990s causes positive 500-h Pa height anomalies south of the Ural Mountains, which promote a southward shift of Ural PAE.

关键词： Ural persistent anomaly Pacific decadal oscillation Atlantic multidecadal oscillation sea ice loss in Barents-Kara Seas

Risk factors of non-arteritic anterior ischaemic optic neuropathy and central retinal artery occlusion

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 869-876页

作者： Chu-Han Ma Cong-Yao Wang ting-ting Dai ting-ting Chen Wen-Hui Zhu Department of Ophthalmology the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080Guangdong ProvinceChina

AIM:To investigate the difference in risk factors between non-arteritic anterior ischaemic optic neuropathy(NAION)and central retinal artery occlusion(CRAO)and develop a predictive diagnostic ***:The study included 37 patients with monocular NAION,2. with monocular CRAO,and 2. with ***,age,and systemic diseases were *** routine,lipids,hemorheology,carotid and brachial artery doppler ultrasound,and echocardiography were *** optic disc area,cup area,and cup-to-disc ratio(C/D)of the unaffected eye in the NAION and CRAO group and the right eye in the hypertension group were ***:The carotid artery intimal medial thickness(C-IMT)of the affected side of the CRAO group was thicker(P=0.039)and its flow-mediated dilation(FMD)was lower(P=0.049)than the NAION *** with hypertension patients,NAION patients had higher whole blood reduced viscosity low-shear(WBRV-L)and erythrocyte aggregation index(EAI;P=0.045,0.037),and CRAO patients had higher index of rigidity of erythrocyte(IR)and erythrocyte deformation index(EDI;P=0.004,0.001).The optic cup and the C/D of the NAION group were smaller than the other two groups(P<0.0001).The diagnostic prediction model showed high diagnostic specificity(83.7%)and sensitivity(85.6%),which was highly related to hypertension,the C-IMT of the affected side,FMD,platelet(PLT),EAI,and C/***:CRAO patients show thicker C-IMT and worse endothelial function than *** and CRAO may be related to abnormal hemorheology.A small cup and small C/D may be involved in *** diagnostic nomogram can be used to preliminarily identify NAION and CRAO.

关键词： non-arteritic anterior ischaemic optic neuropathy central retinal artery occlusion risk factors diagnostic prediction model nomogram