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识解理论视角下《使女的故事》的叙事研究

外国语文研究 2021年第1期7卷 49-56页

作者：严天欣伦敦大学学院应用语言学系

加拿大作家玛格丽特·阿特伍德在其小说《使女的故事》中对女性的压迫与反抗这一主题进行了深刻的探讨,但她并没有将自己的政治理念强加于读者,而是通过不同的叙事策略去激发读者对小说人物形象和主题内涵进行思索和追问。本文通过运用... 详细信息

加拿大作家玛格丽特·阿特伍德在其小说《使女的故事》中对女性的压迫与反抗这一主题进行了深刻的探讨,但她并没有将自己的政治理念强加于读者,而是通过不同的叙事策略去激发读者对小说人物形象和主题内涵进行思索和追问。本文通过运用认知语法识解理论分析小说文本的语法特征,发现小说的双重叙事在语法层面的依据及其产生的阅读体验:顺序扫描和高详细度的语法特征突显主人公的心理视角,强化主人公的自我意识和个体性,让读者对女性的反抗产生乐观的希望;总体扫描和低详细度的语法特征则创造了一种意识形态视角,在这一视角下,奥芙弗雷德的个体独特性和主动性被削弱,成为被凝视的客体,加深了小说的反乌托邦悲剧色彩。

关键词：认知语法识解理论叙事研究《使女的故事》

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可干预因素与关节运动损伤的因果关系

中国组织工程研究 2025年第9期29卷 1953-1962页

作者：董婷婷陈天鑫李妍张晟张磊中国中医科学院望京医院骨关节四科北京市100102

背景:生活方式、代谢特征及营养摄入等干预因素与关节运动损伤的因果关系逐渐得到临床研究的重视,然而可干预因素与关节运动损伤的因果关系尚不明确。目的:运用孟德尔随机化的方法,探讨可干预因素与关节运动损伤的因果关系,为运动损伤... 详细信息

背景:生活方式、代谢特征及营养摄入等干预因素与关节运动损伤的因果关系逐渐得到临床研究的重视,然而可干预因素与关节运动损伤的因果关系尚不明确。目的:运用孟德尔随机化的方法,探讨可干预因素与关节运动损伤的因果关系,为运动损伤预防提供依据。方法:从公开数据库获取可干预因素和关节运动损伤的GWAS数据集,运用逆方差加权法、MR-Egger法、加权中位数法探讨生活方式、代谢特征、营养摄入与关节运动损伤的因果关系。敏感性分析方面,采用Cochran’s Q检验、MR-Egger回归、留一法和MR-PRESSO,以验证结果的稳定性和可靠性。结果与结论:①生活方式方面,咖啡(OR=0.29,95%CI:0.10-0.79,P=0.016)、茶消耗量(OR=0.41,95%CI=0.19-0.85,P=0.017)与足踝关节运动损伤风险下降,咖啡消耗量(OR=3.31,95%CI=1.02-10.73,P=0.046)与肩关节运动损伤风险上升具有潜在因果关系;从未吸烟(OR=0.78,95%CI=0.70-0.87,P=1.49×10^(-5))与足踝关节运动损伤风险下降具有显著因果关系。②代谢特征方面,钙水平(OR=0.88,95%CI=0.79-0.98,P=0.017)与手腕关节运动损伤风险下降具有潜在因果关系。③营养摄入方面,维生素A摄入(OR=1.08,95%CI:1.02-1.13,P=0.007)与膝关节运动损伤风险增加具有潜在因果关系。④敏感性分析方面,Cochran’s Q检验显示存在异质性(P0.05),留一法显示逐个剔除单核苷酸多态性后,结果具有稳定性。⑤此研究初步揭示生活方式、代谢特征及营养摄入等可干预因素对关节运动损伤风险的影响,为关节运动损伤的预防提供研究证据与研究方向。

关键词：孟德尔随机化关节运动损伤可干预因素生活方式代谢特征营养摄入因果关系敏感性分析

Structural uncertainty quantification of Reynolds-Averaged Navier–Stokes closures for various shock-wave/boundary layer interaction flows

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Chinese Journal of Aeronautics 2024年第3期37卷 34-48页

作者： Fanzhi ZENG tianxin ZHANG Denggao TANG Jinping LI Chao yan School of Aeronautic Science and Engineering Beihang UniversityBeijing 100191China School of Aeronautical Engineering Air Force Engineering UniversityXi’an 710038China

Accurate prediction of Shock-Wave/Boundary Layer Interaction(SWBLI)flows has been a persistent challenge for linear eddy viscosity models.A major limitation lies in the isotropic representation of the Reynolds stress,as assumed under the Boussinesq *** studies have shown promise in improving the prediction capability for incompressible separation flows by perturbing the Reynolds-stress anisotropy ***,it remains uncertain whether this approach is effective for SWBLI flows,which involve compressibility and *** address this issue,this study systematically quantifies the structural uncertainty of the anisotropy for oblique SWBLI *** eigenspace perturbation method is applied to perturb the anisotropy tensor predicted by the Menter Shear–Stress Transport(SST)model and reveal the impacts of anisotropy on the prediction of quantities of interest,such as separation and reattachment positions,wall static pressure,skin friction,and heat *** results demonstrate the potential and reveal the challenges of eigenspace perturbation in improving the SST ***,a detailed analysis of turbulent characteristics is performed to identify the source of *** findings indicate that eigenspace perturbation primarily affects turbulent shear stress,while the prediction error of the SST model is more related to turbulent kinetic energy.

关键词： Shock-wave/boundary layer interaction(SWBLI) Turbulence models Uncertainty analysis Eigenspace perturbation Anisotropy

A three-equation transition model with mechanical considerations

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Chinese Journal of Aeronautics 2022年第11期35卷 178-190页

作者： tianxin ZHANG Jianqiang CHEN Yatian ZHAO Zaijie LIU Chao yan School of Aeronautic Science and Engineering Beihang UniversityBeijing 100083China Computational Aerodynamics Institute China Aerodynamics Research&Development CenterMianyang 621000China School of Aeronautics and Astronautics Central South UniversityChangsha 410083China

A three-equation transition model based on the transition V-model is proposed for subsonic flows in this study. Considering the mechanical approximation of the generation process of the pre-transitional vorticities, the value of laminar Reynolds shear stress related to the mean shear deformation was calculated in the original transition V-model. Then a new transition model, named V-SA model, was proposed, which considered the phenomenological process of transition and presented great results for flows with and without pressure gradient. It is well-known that the baseline Shear Stress Transport(SST) turbulence model shows excellent performance of accuracy and robustness in plentiful flow cases, but it is important to predict boundary layer transition. The current model(V-SST) successfully couples the V-model to the SST turbulence model by introducing the effective turbulent viscosity and additional correction terms into the transport equations. A thorough evaluation of its ability to predict transition features is performed versus the well-documented flat plate of ERCOFTAC, including T3A and T3B without pressure gradient, T3L2 and T3L3 with semi-circular leading edge, the three-dimensional 6:1 prolate-spheroid under two angles of attack, and the NLR-7301 airfoil under different Mach numbers. Numerical results show that the current model has an attractive and superior performance in the simulation of boundary layer transition processes.

关键词： Laminar kinetic energy Mechanical consideration Shear stress transport turbulence model Transition model V-model

PD-L1^(+)exosomes from bone marrow-derived cells of tumor-bearing mice inhibit antitumor immunity

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Cellular & Molecular Immunology 2021年第10期18卷 2402-2409页

作者： yan Sun Jufeng Guo Lei Yu tianxin Guo Jiaoli Wang Xian Wang Yinghu Chen Department of Infectious Disease Childrenʼs HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthNational Children's Regional Medical Center310052HangzhouChina Department of Comprehensive Medical Oncology Zhejiang Cancer Hospital310022 HangzhouChina Department of Medical Oncology Sir Run Run Shaw HospitalZhejiang University School of Medicine310020 HangzhouChina Department of Breast Surgery Affiliated Hangzhou First People's HospitalZhejiang University School of Medicine310006 HangzhouChina Laboratory of Cancer Biology The Key Lab of Biotherapy in Zhejiang Sir Run Run Shaw HospitalZhejiang University School of Medicine310020 HangzhouChina Department of Respiratory Medicine Nanjing Medical University211166 NanjingChina Department of Respiratory Medicine Affiliated Hangzhou First People's HospitalZhejiang University School of Medicine310006 HangzhouChina

Tumors escape immune attack by upregulating the surface expression of PD-L1,which interacts with PD-1 on T cells to activate immune inhibitory ***-PD-1 treatments can effectively block this inhibitory signaling and activate antitumor immune ***,anti-PD-1 treatment also has a tumor suppressive effect in patients whose tumor cells do not express *** underlying mechanisms are poorly ***,we report that exosomes from bone marrow-derived cells(BMDCs)in tumor-bearing mice,but not in healthy mice,carry ***-L1 on these exosomes is biofunctional and can inhibit CD8^(+)T cell proliferation and activation in vitro and in *** transfer of exogenous exosomes from BMDCs and the inhibition of the production of endogenous exosomes by BMDCs promote and suppress tumor growth,***-L1^(+)exosomes from BMDCs can be found in tumor *** addition,exosomes from BMDCs promote tumor metastasis in a PD-L1-dependent ***,our results indicate that exosomes from BMDCs play important roles in tumor immunosuppression via PD-L1.

关键词： Bone marrow-derived cells Exosomes PD-L1

MBE Growth and Characterization of Strained Hg Te(111)Films on CdTe/GaAs

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Chinese Physics Letters 2020年第3期37卷 64-68页

作者： Jian Zliang Shengxi Zhang Xiaofang Qiu yan Wu Qiang Sun Jin Zou tianxin Li Pingping Chen State Key Laboratory of Infrared Physics Shanghai Institute of Technical PhysicsChinese Academy of SciencesShanghai 200083 University of Chinese Academy of Sciences Beijing 100049 Materials Engineering The University of QueenslandBrisbaneQueensland 4072A ustralia Centre for Microscopy and Microanalysis The University of Queensland.BrisbaneQueensland 4072Australia

Strained Hg Te thin films are typical three-dimensional topological insulator *** works have focused on Hg Te(100)films due to the topological properties resulting from uniaxial *** this study,strained Hg Te(111)thin films are grown on Ga As(100)substrates with Cd Te(111)buffer layers using molecular beam epitaxy(MBE).The optimal growth conditions for Hg Te films are determined to be a growth temperature of 160℃and an Hg/Te flux ratio of *** strains of Hg Te films with different thicknesses are investigated by highresolution x-ray diffraction,including reciprocal space mapping *** critical thickness of Hg Te(111)film on Cd Te/Ga As is estimated to be approximately 284 nm by Matthews'equations,consistent with the experimental *** high-energy electron diffraction and high-resolution transmission electron microscopy investigations indicate that high-quality Hg Te films are *** exploration of the MBE growth of Hg Te(111)films provides valuable information for further studies of Hg Te-based topological insulators.

关键词： MBE films insulator

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叶菜类蔬菜对重金属富集特征研究

江西农业大学学报 2022年第3期44卷 773-782页

作者：查燕汤婕牛天新杭州市农业科学研究院农作物(生态)所浙江杭州310024 安徽农业大学环境与资源学院安徽合肥210036

【目的】研究旨在揭示不同品种叶菜对重金属的吸收累积特征,筛选重金属低累积型叶菜品种,降低潜在的健康风险。【方法】利用原子吸收光谱仪测定6种叶菜类蔬菜叶片中6种重金属Cd、Cr、Cu、Pb、Ni和Zn含量,分析叶菜累积重金属的空间差异... 详细信息

【目的】研究旨在揭示不同品种叶菜对重金属的吸收累积特征,筛选重金属低累积型叶菜品种,降低潜在的健康风险。【方法】利用原子吸收光谱仪测定6种叶菜类蔬菜叶片中6种重金属Cd、Cr、Cu、Pb、Ni和Zn含量,分析叶菜累积重金属的空间差异及种间差异,计算其富集系数(BF)、综合积累指数(MAI)及捕获率(CR),并对比清洗前后叶菜叶片中重金属含量。【结果】叶菜叶片中重金属含量存在空间差异和种间差异,以农科院叶菜叶片重金属含量最高,苋菜叶片中重金属含量显著高于其他5种叶菜。富集系数由大到小的排序依次为Cd、Zn、Cu、Ni、Cr和Pb,其中Cd富集系数均值大于1,其他元素富集系数均值均小于1。MAI指数由大到小依次排序为叶用番薯(4.77)、苋菜(3.78)、生菜(3.33)≈菠菜(3.26)、杭白菜(2.67)≈青菜(2.65)。6种叶菜均表示出对Pb、Cr有较强的捕获率,其中杭白菜对Pb和Cr的捕获率分别高达60.36%和51.19%。通过对比清洗前后叶菜叶片中重金属含量可知,清洗过的叶菜样品中6种重金属含量均低于未清洗叶菜样品,清洗对叶用番薯中Cr、Zn,青菜和叶用番薯中Pb、杭白菜中Pb、Cr及青菜中Ni有着较为显著的去除效果。【结论】建议在中轻度污染区域优先种植苋菜,在中轻度重金属复合污染土壤中,优先选择对Cd、Cr、Cu、Ni和Pb富集能力较弱的杭白菜进行种植,在大气Pb和Cr污染较高的风险区域避免叶菜露天种植。

关键词：叶菜重金属富集特征捕获率

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6种叶菜吸附颗粒物与叶片微形态特征研究

江西农业大学学报 2021年第6期43卷 1443-1451页

作者：查燕牛天新汤婕杭州市农业科学研究院浙江杭州310024 安徽农业大学安徽合肥230016

【目的】叶菜作为一种特殊的绿色植物,不仅在农业生态系统物质循环和能量流动中发挥着关键作用,而且作为一种大气-土壤交界的重要环境界面,具备显著消减大气颗粒物浓度的生态功能。本研究对杭州市6种常见叶菜叶片不同粒径颗粒物吸附量... 详细信息

【目的】叶菜作为一种特殊的绿色植物,不仅在农业生态系统物质循环和能量流动中发挥着关键作用,而且作为一种大气-土壤交界的重要环境界面,具备显著消减大气颗粒物浓度的生态功能。本研究对杭州市6种常见叶菜叶片不同粒径颗粒物吸附量及叶表微形态特征进行分析,以期为利用叶菜表征区域大气颗粒物污染提供参考依据。【方法】选取青菜Brassicachinensis L、菠菜Spinaciaoleracea L、生菜Lactucasativa ***、苋菜Amaranthustricolor L.杭白菜Brassicachinensis ***、叶用番薯Ipomoeabatatas,采用水洗测量法测定植物表面不同粒径颗粒物吸附量,利用扫描电镜观察叶菜表面的微形态结构,探究叶片表面微形态与颗粒物吸附能力的关系。【结果】(1)不同叶菜叶表面对总颗粒物的吸附能力存在差异,以叶用番薯吸附总颗粒物的能力最强((22.62±4.15)μg/cm^(2)),生菜吸附能力最弱((6.46±1.22)μg/cm^(2))。(2)通过比较叶菜对不同粒径颗粒物的吸附量可知,以叶用番薯对PM_(>10)、PM_(2.5~10)及PM_(0.2~2.5)的能力最强,以生菜吸附PM_(>10)的能力最弱,以杭白菜吸附PM_(2.5~10)能力最弱,以苋菜吸附PM_(0.2~2.5)能力最弱。(3)叶菜叶片以吸附PM_(>10)为主,占总颗粒物质量的75.19%~88.42%,PM_(2.5~10)占总颗粒物质量的7.75%~22.93%,PM_(0.2~2.5)占总颗粒物质量的1.87%~4.19%。(4)通过线性拟合可知,气孔长度、气孔宽度与PM_(>10)质量呈显著性关系,气孔宽度与PM_(0.2~2.5)质量呈显著性关系,本研究结果可为利用叶菜表征区域大气颗粒物污染提供参考依据。【结论】叶用番薯吸附总颗粒物的能力最强,生菜吸附能力最弱。气孔是影响叶菜吸附不同粒径颗粒物的重要因素。

关键词：叶菜颗粒物微形态气孔

基于CaO/CaCO_(3)的高温热化学储能改性机制研究

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工程热物理学报 2023年第9期44卷 2541-2548页

作者：田希坤徐钿昕闫君林尚超赵长颖上海交通大学工程热物理研究所上海200240

基于CaO/CaCO_(3)循环的热化学储能体系由于CaO晶粒的烧结导致储能性能下降。本文从晶格能的角度为材料改性提供筛选标准,发现相结合的改性机制下的高价态金属氧化物能够提升储能材料的循环稳定性。以柠檬酸钙为CaO的前驱体并添加10%摩... 详细信息

基于CaO/CaCO_(3)循环的热化学储能体系由于CaO晶粒的烧结导致储能性能下降。本文从晶格能的角度为材料改性提供筛选标准,发现相结合的改性机制下的高价态金属氧化物能够提升储能材料的循环稳定性。以柠檬酸钙为CaO的前驱体并添加10%摩尔分数TiO_(2)的钙基材料,经15次循环后有效转化率高达0.66,是未改性钙基材料的2.1倍。在材料的制备过程中掺杂TiO_(2)后形成部分CaTiO_(3)的复合相,经改性后的储能材料表观粒径小且能够保持复杂的孔结构,抗烧结性能好。

关键词：热化学储能氧化钙二氧化钛改性机制相结合