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Cramer-Rao lower bound-based observable degree analysis

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Science China(Information Sciences) 2019年第5期62卷 29-31页

作者： Quanbo GE tianxiang chen Hongli HE Zhentao HU School of Automation Hangzhou Dianzi University Chinese Flight Test Establishment College of Computer and Information Engineering Henan University

Dear editor,Controllability and observability are basic concepts in modern control theory that are based on Kalman filtering (KF)[1, 2]. In particular, observability is closely related to state estimation ability [2–4]. The indicator called observable degree(OD) has been used to quantitatively measure the degree of observability [5–7]. However, limited by

关键词： ODA Cramer-Rao lower bound-based observable degree analysis

Two-dimensional layered nanomaterials fortumor diagnosis and treatment

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Medical Review

Medical Review 2023年第3期3卷 205-208页

作者： chengyuan Hong Zhusheng Liu tianxiang chen Aiguo Wu Cixi Institute of Biomedical Engineering International Cooperation Base of Biomedical Materials Technology and ApplicationCAS Key Laboratory of Magnetic Materials and Devices and Zhejiang Engineering Research Center for Biomedical MaterialsNingbo Institute of Materials Technology and EngineeringChinese Academy of Sciences(CAS)Ningbo Key Laboratory of Biomedical Imaging Probe Materials and TechnologyNingbo 315201Zhejiang ProvinceChina Department of Mechanical Materials and Manufacturing EngineeringUniversity of Nottingham Ningbo ChinaNingboZhejiang ProvinceChina

With the evolution of nanomedicine,the past decades witnessed diversified nanomaterials as marvelous antitumor tools ushering in a new era of tumor diagnosis and *** them,two-dimensional layered nano-material as an emerging class of nanomaterials has one dimension less than 100 nm,showing a high specific area and the thinnest sheet-like structure(Liu S,Pan X,Liu *** nanomaterials for photothermal *** Chem Int Ed 2020;59:5890–900).The discovery of graphene drove the exploration of various new two-dimensional layered nanomaterials for tumor diagnosis and treatment including graphene-based nanomaterials,black phosphorus(BP),transition metal dichalcogenides(TMDs),layered double hydroxides(LDHs),and bismuth oxyhalides(BiOX,X=F,Cl,Br,I)(Ma H,Xue *** advances in the photothermal applications of two-dimensional nanomaterial:photothermal therapy and beyond.J Mater Chem 2021;9:17569).On the one hand,they exhibit strong near-infrared(NIR)absorption and the capacity of optimizing corresponding properties by adjusting the crystal *** the other hand,they own unique strengths such as fantastic physicochemical properties(graphene-based nanomaterials),high loading capacity(BP),distinct phase-dependent optical properties(TMDs),a specific chemical response to the tumor microenvironment(LDHs),and large X-ray attenuation coefficient(BiOX).Herein,we briefly introduce three typical two-dimensional layered nanomaterials,their prospects and future research priorities in tumor diagnosis and treatment are concluded.

关键词： tumor diagnosis tumor treatment two-dimensional layered nanomaterials

Einstein Probe discovery of EP240408a: A peculiar X-ray transient with an intermediate timescale

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 222-240页

作者： Wenda Zhang Weimin Yuan Zhixing Ling Yong chen Nanda Rea Arne Rau Zhiming Cai Huaqing cheng Francesco Coti Zelati Lixin Dai Jingwei Hu Shumei Jia Chichuan Jin Dongyue Li Paul O’Brien Rongfeng Shen Xinwen Shu Shengli Sun Xiaojin Sun Xiaofeng Wang Lei Yang Bing Zhang chen Zhang Shuang-Nan Zhang Yonghe Zhang Jie An David Buckley Alexis Coleiro Bertrand Cordier Liming Dou Rob Eyles-Ferris Zhou Fan Hua Feng Shaoyu Fu Johan P.U.Fynbo Lluis Galbany Saurabh W.Jha Shuaiqing Jiang Albert Kong Erik Kuulkers Weihua Lei Wenxiong Li Bifang Liu Mingjun Liu Xing Liu Yuan Liu Zhu Liu Chandreyee Maitra Alessio Marino Itumeleng Monageng Kirpal Nandra Jeremy Sanders Roberto Soria Lian Tao Junfeng Wang Song Wang Tinggui Wang Zhongxiang Wang Qingwen Wu Xuefeng Wu Dong Xu Yanjun Xu Suijian Xue Yongquan Xue Zijian Zhang Zipei Zhu Hu Zou Congying Bao Fansheng chen Houlei chen tianxiang chen Wei chen Yehai chen Yifan chen chenzhou Cui Weiwei Cui Yanfeng Dai Dongwei Fan Ju Guan Dawei Han Dongjie Hou Haibo Hu Maohai Huang Jia Huo Zhenqing Jia Bowen Jiang Ge Jin chengkui Li Junfei Li Longhui Li Maoshun Li Wei Li Zhengda Li Tianying Lian Congzhan Liu Heyang Liu Huaqiu Liu Fangjun Lu Laidan Luo Jia Ma Xuan Mao Haiwu Pan Xin Pan Liming Song Hui Sun Yunyin Tan Qingjun Tang Yihan Tao Hao Wang Juan Wang Lei Wang Wenxin Wang Yilong Wang Yusa Wang Qinyu Wu Haitao Xu Jingjing Xu Xinpeng Xu Yunfei Xu Zhao Xu Changbin Xue Yulong Xue Ailiang Yan Haonan Yang Xiongtao Yang Yanji Yang Juan Zhang Mo Zhang Wenjie Zhang Zhen Zhang Zhen Zhang Ziliang Zhang Donghua Zhao Haisheng Zhao Xiaofan Zhao Zijian Zhao Hongyan Zhou Yilin Zhou Yuxuan Zhu Zhencai Zhu National Astronomical Observatories Chinese Academy of Sciences School of Astronomy and Space Sciences University of Chinese Academy of Sciences Key Laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Institute of Space Sciences (ICE) CSIC Institut d’Estudis Espacials de Catalunya (IEEC) Max Planck Institute for Extraterrestrial Physics Innovation Academy for Microsatellites Chinese Academy of Sciences Department of Physics University of Hong Kong School of Physics and Astronomy University of Leicester School of Physics and Astronomy Sun Yat-sen University Department of Physics Anhui Normal University Shanghai Institute of Technical Physics Chinese Academy of Sciences Physics Department Tsinghua University Nevada Center for Astrophysics University of Nevada Las Vegas Department of Physics and Astronomy University of Nevada Las Vegas South African Astronomical Observatory Department of Astronomy University of Cape Town Department of Physics University of the Free State Université Paris Cité CNRS Astroparticule et Cosmologie Université Paris Cité CEA Paris-Saclay IRFU/DAp-AIM Department of Astronomy Guangzhou University Cosmic Dawn Center (DAWN) Niels Bohr Institute University of Copenhagen Department of Physics and Astronomy Rutgers the State University of New Jersey Institute for Cosmic Ray Research The University of Tokyo ESA/ESTEC Department of Astronomy School of Physics Huazhong University of Science and Technology INAF-Osservatorio Astrofisico di Torino Sydney Institute for Astronomy School of Physics The University of Sydney Department of Astronomy Xiamen University Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University Department of Astronomy University of Science and Technology School of Astronomy and Space Sciences University of Science and Technology of China Institute of Deep Space Sciences Deep Space Exploration Laboratory Department of Astronomy School of Physics and Astronomy Yunnan University Shanghai Astronomical Observatory Chi

We report the discovery of a peculiar X-ray transient,EP240408a,by Einstein Probe （EP） and follow-up studies made with EP,Swift,NICER,GROND,ATCA and other ground-based multiwavelength *** new transient was first detected with Wide-field X-ray Telescope （WXT） on board EP on April 8th,2024,manifested in an intense yet brief X-ray flare lasting for *** flare reached a peak flux of 3.9×10-9erg cm-2s-1in 0.5-4 ke V,～300 times brighter than the underlying X-ray emission detected throughout the *** and more precise follow-up observations by EP/FXT,Swift and NICER confirmed the finding of this new *** X-ray spectrum is non-thermal in 0.5-10 ke V,with a power-law photon index varying *** X-ray light curve shows a plateau lasting for ～4 d,followed by a steep decay till becoming undetectable ～10 d after the initial *** on its temporal property and constraints from previous EP observations,an unusual timescale in the range of 7-23 d is found for EP240408a,which is intermediate between the commonly found fast and long-term *** counterparts have been found in optical and near-infrared,with the earliest observation at 17 h after the initial X-ray detection,suggestive of intrinsically weak emission in these *** demonstrate that the remarkable properties of EP240408a are inconsistent with any of the transient types known so far,by comparison with,in particular,jetted tidal disruption events,gamma-ray bursts,X-ray binaries and fast blue optical *** nature of EP240408a thus remains an *** suggest that EP240408a may represent a new type of transients with intermediate timescales of the order of～10 *** detection and follow-ups of more of such objects are essential for revealing their origin.

关键词： X-ray transients ${\bm~{Einstein~~Probe}}$

Controllable synthesis of layered black bismuth oxidechloride nanosheets and their applications in internal tumor ablation

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Regenerative Biomaterials 2022年第1期9卷 501-510页

作者： Qianlan Fang Yu Xu Lijia Luo Chuang Liu Zihou Li Jie Lin tianxiang chen Aiguo Wu Cixi Institute of Biomedical Engineering International Cooperation Base of Biomedical Materials Technology and ApplicationChinese Academy of Science(CAS)Key Laboratory of Magnetic Materials and Devices and Zhejiang Engineering Research Center for Biomedical MaterialsNingbo Institute of Materials Technology and EngineeringCASNingbo 315201P.R.China University of Chinese Academy of Sciences Beijing 100049P.R.China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516000P.R.China

The recently emerging bismuth oxyhalide(BiOX)nanomaterials are promising indirect band gap photosensitizer for ultraviolet(UV)light-triggered phototherapy due to their unique layered nanosheet ***,the low absorption and poor photothermal conversion efficiency have always impeded their further applications in cancer clinical ***,BiOCl rich in oxygen vacancies has been reported to have fullspectrum absorption properties,making it possible to achieve photothermal property under near-infrared *** 808nm irradiation,the photothermal conversion efficiency of black BiOCl nanosheets(BBNs)is up to 40%.BBNs@PEG can effectively clear primary subcutaneous tumors and prevent recurrence,achieving good synergistic treatment *** results not only broke the limitation of UV on the BiOCl material and provided a good template for other semiconductor materials,but also represent a promising approach to fabricate BBN@PEG a novel,potent and multifunctional theranostic platform for precise photothermal therapy and prognostic evaluation.

关键词： black bismuth oxidechloride nanosheet photothemal therapy tumor photothermal conversion efficiency

On-line Monitoring of Insulation Dielectric Loss Factor Based on Balance Principle

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电力系统自动化 2013年第21期37卷 180-183页

作者： tianxiang chen Zhenhua SHAO Shaozhen QIN Hong TIAN Xiamen University of Technology Xiamen 361024 China Singapore Power Grid Singapore 238164 Singapore

This paper proposes a new on-line measuring method for tan δ of insulation based on passive current sensors. The new method avoids the difficulties encountered during producing sensors with high precision for ratio error and phase displacement error, thus it is cost-effective and of high accuracy. Combining a phase difference algorithm with the computer technology, the method is suitable for micro-controller unit (MCU). The practicability of the method is validated by field tests, thus its anti-interference ability is confirmed.

关键词：介质损耗因数平衡原则在线监测绝缘相位误差高精确度电流传感器位移传感器

A facile fabrication route for binary transition metal oxide-based Janus nanoparticles for cancer theranostic applications

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Nano Research 2018年第10期11卷 5735-5750页

作者： M. Zubair Iqbal Wenzhi Ren Madiha Saeed tianxiang chen Xuehua Ma Xu Yu Jichao Zhang Lili Zhang Aiguo Li Aiguo Wu iang Province & Division of Functional Materials and Nano devices Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Ningbo 315201 China ShanghaiSynchrotron Radiation Facility Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai201204 China

Janus nanoparticles （JNPs） have multiple configurations for molecular imaging, targeting, and therapeutic effects on cancers; these properties have made these particles attractive for biomedical applications. Nonetheless, smart strategies for the controlled synthesis in a liquid phase and exploration of the appropriate applications of JNPs remain a challenge. In this study, a unique liquid-phase method was applied to fabricate Mn3O4-TiO2/ZnO/Fe3O4 multifunctional binary transition metal oxide-based JNPs, using the concept of epitaxial growth and lattice mismatch among synthesized materials. Transmission electron microscopy and scanning transmission electron microscopy results revealed that the created materials are embedded in the form of dimers with good dispersion and homogeneous growth in a nonpolar solvent. Pluronic F-127-coated MnBO4- TiO2 JNPs were utilized as a contrast agent in T1-weighted magnetic resonance imaging （MRI） and in photodynamic therapy （PDT） for cancers in vitro and in vivo. In vivo T1-weighted MRI of the heart, liver, and kidneys in mice after intravenous injection of the nanoparticles revealed high sensitivity and biocompatibility of as-synthesized Mn3O4--TiO2 JNPs. Results of synchrotron X-ray fluorescence microscopy mapping showed the stability of the nanocomposites and efficiency of penetration into the cytoplasm and perinuclear area. Inorganic TiO2 photosensitizers showed promising tumor ablation performance in PDT in vitro and in vivo at low intensity of UV irradiation （5.6 ***-2） because of their ultrasmall size and photodegradable stability. These results reveal that multifunctional Mn3O4-TiO2 JNPs enhance a T1-weighted MRI contrast and have excellent properties for PDT and therefore, may be a novel agent for cancer theranostics.

关键词： Janus nanostructures manganese oxide magnetic resonance imaging photodynarnic therapy breast cancer

Primary Study of Power-Exchanging Trans- action Model Among Price-Varied Power Plants in Practical Conditions

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Electricity 2005年第3期16卷 12-16页

作者： chen tianxiang Zhang Baohui Electrical Engineering College Xi＇an Jiaotong University Gansu Electric Power Company

At present, electricity price to grid of domestic power plants is priced by the national administration based on the policy of "one power plant with one electricity price to grid," which is difficult to realize real bidding for access to grid in practice in a short term. This paper presents one kind of power-exchanging transaction model among price-varied power plants, which will be beneficial to price-varied power plants without any loss of profits of them and guarantee state-owned assets profits in minimum loss with no promotion of average price limit by power plants. Under ideal conditions, the computation results showed the sufficiency and necessity of power-exchanging transaction and maximum similarity with the requirements of optimized resources disposition in economics. The presented model is shown to be full of practicability and has been used in some part of power market.

关键词： different price power plant power exchange transaction model

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如何赋予省级政府更多自主权?

探索 2019年第1期 19-26页

作者：陈天祥中山大学中国公共管理研究中心/政治与公共事务管理学院广东广州510275

赋予省级政府更多自主权首先必须厘清政府与市场、社会的职能边界,进而确定中央政府与省级政府之间在经济调节、市场监管、社会管理和公共服务四大政府职能领域的分工。针对省级政府职权配置中存在的问题,如法制建设、"三定"方案、政府... 详细信息

赋予省级政府更多自主权首先必须厘清政府与市场、社会的职能边界,进而确定中央政府与省级政府之间在经济调节、市场监管、社会管理和公共服务四大政府职能领域的分工。针对省级政府职权配置中存在的问题,如法制建设、"三定"方案、政府权责清单制度和央地间的权力运行机制等,从四个方面着手将赋予省级政府更多自主权落到实处:夯实赋予省级政府更多自主权的宪制基础;完善政府职责体系,为赋予省级政府更多自主权打下坚实的微观制度基础;规范央地间的权力运行机制,约束不当的行政命令干预行为;完善配套措施,实现省级政府履职过程中的权责对称。

关键词：省级政府更多自主权法制建设政府职责配置

政府绩效管理研究:回归政治与技术双重理性本义

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浙江大学学报（人文社会科学版） 2011年第4期41卷 16-25页

作者：陈天祥中山大学中国公共管理研究中心广东广州510275

政府绩效管理是政治理性与技术理性的统一体,但目前我国学术界在该领域的研究存在明显的重技术理性而轻政治理性的倾向,主要表现在:追求作为一种管理技术系统的自洽性,热衷于以技术手段设计和开发政府绩效评估指标体系,以技术理性代替... 详细信息

政府绩效管理是政治理性与技术理性的统一体,但目前我国学术界在该领域的研究存在明显的重技术理性而轻政治理性的倾向,主要表现在:追求作为一种管理技术系统的自洽性,热衷于以技术手段设计和开发政府绩效评估指标体系,以技术理性代替政治理性探讨政府绩效管理机制,沉湎于对技术的精细化追求。今后,政府绩效管理研究领域可从以下几个方面寻求突破:强化政治理性研究取向,实现政治理性与技术理性的有机结合;跳出技术理性主导下研究视角的短视陷阱,立足于探讨政府绩效管理的学科"大问题";致力于本土关照,探索融政治理性与技术理性于一体的中国特色的政府绩效管理机制;从政府再造的系统角度探讨政府绩效管理的关联问题,促进政府治理模式转型。

关键词：政府绩效管理政治理性技术理性