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Plant Communications 2023年第2期4卷 1-3页

作者： xin wei Qing Liu Tingting Sun Xiaozhen Jiao Chaolei Liu Yufeng Hua Xi Chen Kejian Wang State Key Laboratory of Rice Biology China National Rice Research InstituteChinese Academy of Agricultural SciencesHangzhou 310006China Hainan Yazhou Bay Seed Laboratory Sanya 572025China

Dear Editor,Genetic breeding involves the recombination and selection of various valuable *** crossover(CO)promotes the generation of new allelic combinations on chromosomes,which is essential for breeding elite varieties(Wijnker and de Jong,2008).An increase in CO promotes genetic diversity,whereas a decrease can rapidly stabilize excellent traits(Mercier et al.,2015).Furthermore,the complete elimination of CO facilitates heterotic fixation during apomixis(Wang et al.,2019).

关键词： breeding elite elimination

The environment of C-and S-shaped radio galaxies

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Research in Astronomy and Astrophysics 2019年第9期19卷 55-62页

作者： Yu-xing Liu Hai-Guang Xu Dong-Chao Zheng wei-tian Li Zheng-Hao Zhu Zhi-Xian Ma Xiao-Li Lian School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai200240China Tsung-Dao Lee Institute/IFSA Collaborative Innovation Center Shanghai Jiao Tong UniversityShanghai200240China Department of Electronic Engineering Shanghai Jiao Tong UniversityShanghai200240China

We study the environment of radio galaxies with different morphological types using the Proctor sample, which was built from the Faint Images of the Radio Sky at Twenty-Centimeters(FIRST) survey archive. Among the 15 radio galaxy types classified by Proctor, 199 C-shaped(i.e., wide-or narrow-angle tail) and 203 S-shaped(i.e., S-or Z-shaped) sources are selected in this work, which are located in the redshift range of 0.02 < z < 1, because these two subsamples are relatively larger than the other subsamples in the Proctor sample. By cross-matching these radio galaxies with the optical sources drawn from the Sloan Digital Sky Survey(SDSS) database and counting the SDSS sources with an r-band absolute magnitude brighter than –19 located within a 0.5 Mpc distance around each source(i.e., the richness), we find that the fraction of C-shaped sources with a richness above 10 is larger than that of S-shaped sources. We have also correlated the radio galaxies in our sample with the brightest cluster galaxies(BCGs) defined in the NASA/IPAC Extragalactic Database(NED), and infer that the C-shaped sources are more likely to be BCGs than the S-shaped sources. These results support the idea that C-shaped radio galaxies often reside in a richer environment than radio galaxies with other morphological types.

关键词： galaxies:statistics galaxies:structure methods:data analysis

Genome-wide association and linkage mapping strategies reveal genetic loci and candidate genes of phosphorus utilization in soybean

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Journal of Integrative Agriculture 2022年第9期21卷 2521-2537页

作者： ZHANG Hua WU Hai-yan tian Rui KONG You-bin CHU Jia-hao xinG xin-zhu DU Hui JIN Yuan LI Xi-huan ZHANG Cai-ying State Key Laboratory of North China Crop Improvement and Regulation/Hebei Agricultural University Baoding 071001P.R.China

Insufficient available phosphorus in soil has become an important limiting factor for the improvement of yield and quality in soybean. The mining of QTLs and candidate genes controlling soybean phosphorus utilization related traits is a necessary strategy to solve this problem. In this study, 11 phosphorus utilization related traits of a natural population of 281 typical soybean germplasms and a recombinant inbred line(RIL) population of 270 lines were evaluated under different phosphorus conditions at two critical stages: the four-leaf stage as the seedling critical stage was designated as the Tstage, and the six-leaf stage as the flowering critical stage was designated as the Tstage. In total, 200 single nucleotide polymorphism(SNP) loci associated with phosphorus utilization related traits were identified in the natural population, including 91 detected at the Tstage, and 109 detected at the Tstage. Among these SNP loci, one SNP cluster(s715611375, ss715611377, ss715611379 and ss715611380) on Gm12 was shown to be significantly associated with plant height under the low phosphorus condition at the Tstage, and the elite haplotype showed significantly greater plant height than the others. Meanwhile, one pleiotropic SNP cluster(ss715606501, ss715606506 and ss715606543) on Gm10 was found to be significantly associated with the ratio of root/shoot, root and total dry weights under the low phosphorus condition at the Tstage, and the elite haplotype also presented significantly higher values for related characteristics under the phosphorus starvation condition. Furthermore, four co-associated SNP loci(ss715597964, ss715607012, ss715622173 and ss715602331) were identified under the low phosphorus condition at both the Tand Tstages, and 12 QTLs were found to be consistent with these genetic loci in the RIL population. More importantly, 14 candidate genes, including MYB transcription factor, purple acid phosphatase, sugar transporter and HSP20-like chaperones superfamily ge

关键词： soybean phosphorus utilization GWAS linkage mapping genetic loci candidate genes

Femtosecond Time-Resolved Resonance-Enhanced CARS of Gaseous Iodine at Room Temperature

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Chinese Physics Letters 2011年第4期28卷 216-219页

作者： HE Ping FAN Rong-wei XIA Yuan-Qin YU xin YAO Yong CHEN De-Ying National Key Laboratory of Science and Technology on Tunable Laser Institute of Opto-electronicsHarbin Insitute of TechnologyHarbin 150080 College of Basic Sciences Harbin University of CommerceHarbin 150028 Department of Electronic and Information Engineering Shenzhen Graduate SchoolHarbin Institute of TechnologyShenzhen 518055

Time-resolved resonance-enhanced coherent anti-Stokes Raman scattering(CARS)is applied to investigate molecular dynamics in gaseous iodine.40fs laser pulses are applied to create and monitor the high vibrational states of iodine at room temperature(corresponding to a vapor pressure as low as about 35 Pa)by femtosecond timeresolved *** on the time delay between the probe pulse and the pump/Stokes pulse pairs,the high vibrational states both on the electronically ground states and the excited states can be detected as oscillations in the CARS transient *** is proved that the femtosecond time-resolved CARS technique is a promising candidate for investigating the molecular dynamics of a low concentration system and can be applied to environmental and atmospheric monitoring measurements.

关键词： pump Femto scattering

等压假设下考虑化学反应动力学影响的约束爆炸准静态压力的计算

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爆炸与冲击 2013年第4期33卷 375-380页

作者：钟巍田宙西北核技术研究所陕西西安710024

为研究约束爆炸后爆炸产物与约束空间内的氧气发生化学反应对约束爆炸准静态压力的影响,从能量守恒和理想气体状态方程出发,基于爆炸后产物膨胀过程的等压假设模型,建立了约束爆炸准静态压力计算公式,并对TNT炸药爆炸后发生的化学反应... 详细信息

为研究约束爆炸后爆炸产物与约束空间内的氧气发生化学反应对约束爆炸准静态压力的影响,从能量守恒和理想气体状态方程出发,基于爆炸后产物膨胀过程的等压假设模型,建立了约束爆炸准静态压力计算公式,并对TNT炸药爆炸后发生的化学反应与约束空间内准静态压力大小的关系进行分析。计算得到不同药量体积比下,TNT炸药约束爆炸后的准静态压力,计算结果与实验结果符合较好,可应用于其他类型炸药,并为预测约束爆炸后的准静态压力提供理论依据和估算方法。

关键词：爆炸力学准静态压力等压假设约束爆炸药量体积比

Dual transformation therapy for giant hepatocellular carcinoma: Two case reports and review of literature

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World Journal of Gastrointestinal Surgery 2023年第9期15卷 2089-2097页

作者： Qiang Gao Guang-Zhi Zhu Chuang-Ye Han xin-Ping Ye Hua-Sheng Huang Shu-tian Mo Tao Peng Department of Hepatobiliary Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530000Guangxi Zhuang Autonomous RegionChina

BACKGROUND In the translational therapy of giant hepatocellular carcinoma(HCC),hepatic arterial infusion chemotherapy(HAIC)combined with anti-PD-1 immunotherapy and tyrosine kinase inhibitors(TKI)after laparoscopic portal vein ligation(PVL)is extremely *** is a dual conversion therapy that combines surgery and ***,we report two cases of successful surgical completion after dual conversion *** SUMMARY We report that a 54-year-old man and a 69-year-old woman were diagnosed with primary HCC combined with hepatitis B cirrhosis(case 2 also combined with fatty liver)on physical *** to the insufficient residual liver volume assessed before surgery,laparoscopic right PVL was performed,followed by HAIC combined with anti-PD-1 immunotherapy and ***,surgical resection was successfully completed,and pathology confirmed that the tumor was mostly necrotic(90%)in one case,and no live tumor tissue was found in the other *** In the process of surgical transformation,our treatment plan takes into account the control and transformation of oncology at the same time,which is expected to provide more opportunities for radical hepatectomy and improve the prognosis of patients with large liver cancer.

关键词： Giant hepatocellular carcinoma Laparoscopic right portal vein ligation hepatic arterial infusion chemotherapy Anti-PD-1 immunotherapy Tyrosine kinase inhibitor Case report

Advance in yellowing mechanism and the regulation technology of post-harvested broccoli

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Food Quality and Safety 2020年第3期4卷 107-113页

作者： Feng Luo Huixin Fang Baodong wei Shunchang Cheng Qian Zhou xin Zhou Xuan Zhang Yingbo Zhao Shujuan Ji Department of Food Science Shenyang Agricultural UniversityShenyangChina Department of Food Science and Engineering Jinzhou Medical UniversityJinzhouChina

Yellowing is one of the main problems of quality deterioration in the storage,transportation,and sales of post-harvested broccoli,which seriously affects the commodity value of ***,it is of significance to understand the mechanism of the process and develop effective regulation *** this review,we expounded the changes in the appearance of the flower ball,bud morphology,and calyx cell structure,as well as endogenous pigment metabolism,accompanying the yellowing process of *** addition,recent research on the molecular mechanism of yellowing was summarized from the aspects of transcriptome analysis and transcription ***,the progress on the control technology of broccoli yellowing was reviewed.

关键词： broccoli yellowing pigment metabolism transcriptome transcription factor

Down-regulation of microRNA-23a promotes pancreatic ductal adenocarcinoma initiation and progression by up-regulation of FOXM1 expression

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Genes & Diseases 2024年第5期11卷 456-469页

作者： Lixin Liang tian Cai Xiaojia Li Jianhong An Sen Yu Yang Zhang Fengjie Guo Fang wei Jie He Keping Xie Tingting Jiang Center for Pancreatic Cancer Research South China University of Technology School of MedicineGuangzhouGuangdong 510006China Department of Laboratory Medicine The Sixth Affiliated Hospital and Nanhai People’s HospitalSouth China University of Technology School of MedicineFoshanGuangdong 528200China The Second Affiliated Hospital and Guangzhou First People’s Hospital South China University of Technology School of MedicineGuangzhouGuangdong 510006China

Transcriptional factor Forkhead box M1(FOXM1)plays an important role in pancreatic ductal adenocarcinoma(PDAC)development and *** molecular mechanisms underlying its dysregulation remain *** identified and functionally validated the microRNAs(miRNAs)that critically regulate FOXM1 expression in *** expression levels of miRNA-23a(miR-23a-3p and-5p)were altered in PDAC cell lines and their effects on FOXM1 signaling and cell proliferation and migration and tumorigenesis were examined in vitro and in vivo using mouse PDAC *** with non-tumor pancreatic tissues,PDAC tissues and cell lines exhibited significantly reduced levels of miR-23a *** miR-23a expression and concomitant increase in FOXM1 expression were also observed in acinar-toductal metaplasia and pancreatic intraepithelial neoplasia,the major premalignant lesions of *** expression of miR-23a reduced the expression of FOXM1 and suppressed cell proliferation and migration in PDAC cells,whereas the inhibitors of miR-23a did the *** or reduced levels of miR-23a increased the levels of FOXM1 expression,while increased expression of FOXM1 down-regulated miR-23a expression,suggesting that miR-23a and FOXM1 were mutual negative regulators of their expression in PDAC ***,the miR-23a/FOXM1 signaling axis is important in PDAC initiation and progression and could serve as an interventional or therapeutic target for patients with early or late stages of PDAC.

关键词： FOXM1 Gene expression Gene regulation MicroRNA Pancreatic cancer Targeted therapy

Synthesis of Arsamacrocyclic Polyethers

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Chinese Chemical Letters 1999年第8期10卷 665-666页

作者： xin You CHEN Guo Feng YU Wen tian TAO (Department of Chemistry. Xiaogan Teachers College,Hubei 432100)(Department of Chemistry, Wuhan University,Wuhan 430072) Department of Chemistry Xiaogan Teachers College Hubei 432100 China Department of Chemistry Wuhan University Wuhan 430072 China

The synthesis of eight new arsamacrocyclic Polyethers was described. The structures of these compounds were characterized by elemental analysis, IR, H-1-NMR and MS.

关键词： macrocyclic compound arsamacrocyclic polyether synthesis

Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia

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Signal Transduction and Targeted Therapy 2020年第1期5卷 2345-2347页

作者： wei Zhou Yisi Liu Dongdong tian Cheng Wang Sa Wang Jing Cheng Ming Hu Minghao Fang Yue Gao Department of Pharmaceutical Sciences Beijing Institute of Radiation Medicine100850 BeijingP.R.China School of Nursing Capital Medical University100069 BeijingP.R.China Department of Pharmacy Hebei General Hospital050000 ShijiazhuangP.R.China Department of Orthopedics First Medical CenterGeneral Hospital of Chinese PLA100853 BeijingP.R.China Emergency Department The Second Affiliated Hospital of Zhejiang University School of Medicine310009 HangzhouP.R.China Emergency Surgery Department Tongji Hospital Affiliated to Tongji Medical CollegeHuazhong University of Science and Technology430030 WuhanP.R.China Intensive Care Unit Wuhan Pulmonary Hospital430030 WuhanP.R.China Emergency and Intensive Care Unit Tongji Hospital Affiliated to Tongji Medical CollegeHuazhong University of Science and Technology430030 WuhanP.R.China

Dear Editor,Since last December,the outbreak of 2019-nCoV in Wuhan has caused ever-increasing attention and public panic all over the *** to February 9,2020,40,171 patients had been diagnosed with 2019-nCoV infection,including 6484(16.14%)severe cases and 908 deaths(2.27%).Compared to SARS and MERS,2019-nCoV appears to be much more contagious but less lethal,as most patients have mild symptoms and good prognosis1,***,according to the Chinese government’s daily report,13.2–21.3%of patients with 2019-nCoV infection developed into severe or fatal illness(Fig.S1a),which is characterized by the rapid development to acute respiratory distress syndrome(ARDS)or septic *** with an increasing number of confirmed cases,the cumulative total of severe patients with 2019-nCoV is growing(Fig.S1b).Treatment of these critically ill patients is becoming one of the major challenges we are facing.

关键词： distress acute precise