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Coronary plaque response after drug eluting stent implantation assessed by serial optical coherence tomography analysis

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Chinese Medical Journal 2011年第22期124卷 3752-3756页

作者： tian feng chen yun-dai chen lian sun zhi-jun liu chang-fu guo jun jin qin-hua wang jin-da gai lu-yue Department of Cardiology Chinese People＇s Liberation Army General Hospital Beijing 100853 China

Background In general, percutaneous coronary intervention （PCI） relieves vessel stenosis by implantation of a stent, however, the relationship between plaque characteristics and response after stenting is not clear. Methods We enrolled 68 patients （68 vessels） with diagnosed unstable angina pectoris that prospectively underwent PCI and an optical coherence tomography （OCT） examination was done before and after stenting. Coronary plaques were classified as fibrous, lipid-rich and calcified plaque according to OCT examination, and fibrous cap thickness, lumen eccentricity, stent expansion, stent malapposition, tissue prolapse, thrombosis, dissection and stent symmetry were noted. Results The frequency of prolapse was higher in lipid-rich plaques than fibrous plaques （85% vs. 40%, P 〈0.001）. Dissection most often occurred in fibrous plaque compared with lipid-rich and calcified plaques （60% vs. 32% vs. 29%, P 〈0.001）. The frequency of stent strut malapposition in calcified plaques was higher than firous and lipid-rich plaques （71% vs. 40% vs. 5%, P 〈0.001）. In-stent micro-thrombosis was detected only in lipid-rich plaques, with a frequency of 37% （15/41）. The risk factors of micro-thrombosis after PCI were cap thickness （OR 0.903, 95% CI 0.829-0.985）, lumen eccentricity （OR 1.147, 95% CI 1.012-1.30）, and stent length （OR 1.495, 95% CI 1.032-2.166）. Conclusion Plaque response after PCI is associated with its characteristics, and of those, micro-thrombosis after stenting in lipid-rich plaques was the most significant finding and can be predicted.

关键词： coronary heart disease, optical coherence tomography plaque, stent

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Evaluation of neointimal coverage in patients with coronary artery aneurysm formation after drug-eluting stent implantation by optical coherence tomography

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Chinese Medical Journal 2013年第11期126卷 2092-2097页

作者： tian feng chen yun-dai chen lian sun zhi-jun guo jun jin qin-hua liu chang-N wang jin-da liu Hong-bin Department of Cardiology Chinese People's Liberation ArmyGeneral Hospital Beijing 100853 China

Background The vessel healing in patients with coronary artery aneurysms （CAA） that form after drug-eluting stent （DES） implantation is not clear. This study aims to assess the vessel healing in patients with CAA formation after DES implanation. Methods From june 2008 to August 2011, follow-up coronary angiography was conducted on 1160 patients who underwent percutaneous coronary intervention （PCI）. The average period of follow-up was about （18.95±13.05） months. A total of 175 patients who underwent DES implantation into de novo lesions and who underwent coronary angiography and optical coherence tomography （OCT） examination during follow-up were identified. Patients were divided into the CAA group （n=31） and non-CAA group （n=144） based on the results of the coronary angiography. The cardiac events including angina and acute myocardial infarction were noted; in addition, the neointimal thickness and the frequency of strut malapposition and strut uncoverage were also noted. Results A greater proportion of incomplete neointimal coverage （17.17% vs. 1.90%, P 〈0.001） and strut malapposition （18.20% vs. 1.38%, P 〈0.001） were observed in the CAA group. The neointimal thickness in the CAA group was significantly thinner than that in the non-CAA group （（146.6±94.8） μm vs. （192.5＋97.1）μm, P 〈0.001）, as detected via OCT. Patients with CAA formation had a higher frequency of cardiac events including angina pectoris （25.81% vs. 6.25%, P=0.001） and acute myocardial infarction （9.68% vs. 0.13%, P=0.002） and thrombosis （16.13% vs. 0.69%, P 〈0.001）. The longitudinal length of the CAA in the cardiac event group was significantly longer than in the no cardiac event group （（20.0±9.07） mm vs. （12.05±5.38） ram, P=0.005）. Conclusion CAA formation after DES implantation is frequently associated with cardiac events as a result of stent malapposition and incomplete neointimal coverage.

关键词： optical coherence tomography coronary artery aneurysms drug-eluting stent neointimal coverage

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Thrombosis and morphology of plaque rupture using optical coherence tomography

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Chinese Medical Journal 2013年第6期126卷 1092-1095页

作者： guo jun chen yun-dai tian feng liu Hong-bin chen lian sun zhi-jun REN Yi-hong jin qin-hua liu chang-fu HAN Bao-shi gai lu-yue YANG Ting-shu Department of Cardiology Chinese People's Liberation Army General Hospital Beijing 100853 China

Background Thrombosis following plaque rupture is the main cause of acute coronary syndrome, but not all plaque ruptures lead to thrombosis. There are limited in vivo data on the relationship between the morphology of ruptured plaque and thrombosis. Methods We used optical coherence tomography （OCT） to investigate the morphology of plaque rupture and its relation to coronary artery thrombosis in patients with coronary heart disease. Forty-two patients with coronary artery plaque rupture detected by OCT were divided into two groups （with or without thrombus） and the morphological characteristics of ruptured plaque, including fibrous cap thickness and broken cap site, were recorded. Results The fibrous cap of ruptured plaque with thrombus was significantly thinner compared to caps without thrombus （（57.00＋17.00） Bm vs. （96.00＋48.00） Bm; P=0.0076）. Conclusions Plaque rupture associated with thrombosis occurs primarily in plaque covered by a thin fibrous cap. Thick fibrous caps are associated with greater stability of ruptured plaque.

关键词： optical coherence tomography thrombosis plaque rupture

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Optical coherence tomography assessment of edge dissections after drug-eluting stent implantation in coronary artery

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Chinese Medical Journal 2012年第6期125卷 1047-1050页

Background Edge dissections after coronary stent implantation are associated with increased short-term risk of major adverse cardiovascular events. The incidence and outcome of edge dissections after coronary stent implantation were reportedly different using different imaging techniques. We used optical coherence tomography （OCT） to assess the incidence, morphological findings and related factors of edge dissections after drug-eluting stent （DES） implantation. Methods Totally 42 patients with 43 de novo lesions in 43 native arteries undergoing DES implantation with OCT imaging were enrolled in this study. Results Nine edge dissections were detected in 43 arteries after DES implantation. There were four morphological patterns of stent edge dissections indentified in this study：（1） superficial intimal tears （n=3）, （2） subintimal dissections （n=4）, （3） split of media （n=1）, （4） disruption of the fibrotic cap of plaque （n=1）. Stent edge expansion and stent expansion were both higher in the group with dissections than those in the group without dissections （1.682±0.425 vs. 1.229±0.285, P=0.0290; 1.507±0.445 vs. 1.174±0.265, P=0.0072）. Conclusions The incidence of stent edge dissections detected by OCT was 21%. Stent edge dissection is related with stent edge expansion and stent expansion.

关键词： optical coherence tomography stent dissections

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-jun Bi Yuanjie Bi tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi junsong Cang guofu Cao Jianshe Cao Antoine Chance Xuejun chang yue chang Zhe chang Xinyuan chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin chen danping chen fuqing chen fusan chen Gang chen guoming chen hua-Xing chen Huirun chen jinhui chen Ji-Yuan chen Kai chen Mali chen Mingjun chen Mingshui chen Ning chen Shanhong chen Shanzhen chen Shao-Long chen Shaomin chen Shiqiang chen tianlu chen Wei chen Xiang chen Xiaoyu chen Xin chen Xun chen Xurong chen Ye chen Ying chen Yukai chen Zelin chen Zilin chen Gang chen Boping chen Chunhui chen Hok Chuen cheng huajie cheng Shan cheng Tongguang cheng yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-yun dai Xinchen dai Xuwen dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-tian Deng zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille dalian Minzu University DalianLiaoning dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP jinR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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Significant loss of soil inorganic carbon at the continental scale

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National Science Review 2022年第2期9卷 13-20页

作者： Xiao-Dong Song Fei Yang hua-Yong Wu jing Zhang De-cheng Li feng liu Yu-guo Zhao jin-Ling Yang Bing Ju Chong-Fa Cai Biao huang huai-Yu Long Ying lu yue-Yu Sui Qiu-Bing wang Ke-Ning Wu feng-Rong Zhang Ming-Kui Zhang Zhou Shi Wan-Zhu Ma Gang Xin zhi-Ping Qi qing-Rui chang En Ci da-Gang Yuan Yang-Zhu Zhang jun-Ping Bai Jia-Ying chen Jie chen Yin-jun chen yun-Zhong Dong Chun-Lan Han Ling Li Li-Ming liu Jian-jun Pan fu-Peng Song fu-jun sun Deng-feng wang tian-Wei wang Xiang-hua Wei Hong-Qi Wu Xia Zhao qing Zhou Gan-Lin Zhang State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences College of Advanced Agricultural Sciences University of Chinese Academy of Sciences College of Resources and Environment Huazhong Agricultural University Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences College of Natural Resources and Environment South China Agricultural University Northeast Institute of Geography and Agroecology Chinese Academy of Sciences College of Land and Environment Shenyang Agricultural University School of Land Science and Technology China University of Geosciences College of Land Science and Technology China Agricultural University College of Environmental and Resource Sciences Zhejiang University Institute of Digital Agriculture Zhejiang Academy of Agricultural Sciences College of Agriculture Heilongjiang Bayi Agricultural University Tropical Crops Genetic Resources Institute Chinese Academy of Tropical Agricultural Sciences College of Natural Resources and Environment Northwest A & F University College of Resources and Environment Southwest University College of Resources Sichuan Agricultural University College of Resources and Environment Hunan Agricultural University Institute of Agricultural Product Quality Standard and Testing Research Tibet Academy of Agricultural and Animal Husbandry Sciences School of Agricultural Sciences Zhengzhou University Institute of Agriculture Environment and Resources Research Shanxi Academy of Agricultural Sciences College of Resources and Environment Henan Agricultural University College of Resources and Environment China Agricultural University College of Resources and Environmental Sciences Nanjing Agricultural University College of Resources and Environment Shandong Agricultural University Agricultural College Guangxi University College of Grassland and Environment Science Xinjiang Agricultural University College of Geographical Science Qinghai Normal University

Widespread soil acidification due to atmospheric acid deposition and agricultural fertilization may greatly accelerate soil carbonate dissolution and ***,to date,few studies have addressed these ***,we use meta-analysis and nationwide-survey datasets to investigate changes in soil inorganic carbon(SIC) stocks in *** observe an overall decrease in SIC stocks in topsoil(0-30 cm)(11.33 g C m-2yr-1) from the 1980 s to the 2010 *** SIC stocks have decreased by～8.99±2.24%(1.37±0.37 Pg C).The average SIC losses across China(0.046 Pg C yr-1) and in cropland(0.016 Pg C yr-1) account for～17.6%-24.0% of the terrestrial C sink and 57.1% of the soil organic carbon sink in cropland,*** deposition and climate change have profound influences on SIC *** estimate that～19.12%-19.47% of SIC stocks will be further lost by *** consumption of SIC may offset a large portion of global efforts aimed at ecosystem carbon sequestration,which emphasizes the importance of achieving a better understanding of the indirect coupling mechanisms of nitrogen and carbon cycling and of effective countermeasures to minimize SIC loss.

关键词： China soil inorganic carbon stocks global change carbonate soil acidification

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光学相干断层成像评价不同类型药物洗脱支架置入术后的内膜覆盖

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中华心血管病杂志 2011年第3期39卷 204-207页

作者：田峰陈韵岱陈练孙志军刘宏斌刘长福郭军王锦达解放军总医院心内科北京100853

目的应用光学相干断层成像（OCT）对比不同类型药物洗脱支架（DES）置人后的内膜覆盖情况。方法人选62例在我院置人DES（15．3±5．7）个月后行OCT检查的患者，依据置人支架类型分为Cypher支架组（病例数=26，支架数=57）、Endeavor支... 详细信息

目的应用光学相干断层成像（OCT）对比不同类型药物洗脱支架（DES）置人后的内膜覆盖情况。方法人选62例在我院置人DES（15．3±5．7）个月后行OCT检查的患者，依据置人支架类型分为Cypher支架组（病例数=26，支架数=57）、Endeavor支架组（病例数=17，支架数：23）和Firebird支架组（病例数=19，支架数=32）。对所有支架节段进行OCT检查后应用LightLab系统配备的软件进行图像分析。以64、168和366μm为分界点将增生内膜厚度进行区问划分，评价3种DES的内膜覆盖厚度以及内膜增生的匀称性。结果3组的内膜完全覆盖率差异无统计学意义（P〉0．05）。内膜增生厚度Cypher支架组为（178．7±11．9）μm、Endeavor支架组为（228．7±17．1）μm、Firebird支架组为（170．3±13．3）μm，任意2组间比较差异均有统计学意义（均P〈0．05）。Cypher支架组内膜增生均匀性优于Firebird支架组，Firebird支架组优于Endeavor支架组。结论不同类型DES置入后的内膜覆盖情况存在荠异。OCT可以评价不同类到DES问内障增毕均匀忡的善导．

关键词：冠状动脉疾病支架体层摄影术光学相干增生

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Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients

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Chinese Medical Journal 2013年第12期126卷 2276-2280页

作者： ZHENG Ying CAI Guang-yan chen Xiang-mei fu Ping chen Jiang-hua DING Xiao-qiang YU Xue-qing LIN Hong-li liu Jian XIE Ru-juan wang Li-ning NI Zhao-hui liu fu-you YIN Ai-ping XING chang-ying wang Li SHI Wei liu Jian-she HE Ya-ni DING guo-hua LI Wen-ge WU Guang-li MIAO Li-ning chen Nan SU Zhen MEI chang-lin ZHAO Jiu-yang GU Yong BAI yun-kai luO Hui-min LIN Shan chen Meng-hua GONG Li YANG Yi-bin YANG Xiao-ping LI Ying WAN Jian-xin wang Nian-song LI Hai-ying XI Chun-sheng HAO Li XU Yan FANG jing-ai liu Bi-cheng LI Rong-shan wang Rong ZHANG jing-hong wang Jian-qin LOU Tan-qi SHAO feng-min MEI feng liu zhi-hong YUAN Wei-jie sun Shi-ren ZHANG Ling ZHOU Chun-hua chen qin-kai JIA Shun-lian GONG zhi-feng GUAN Guang-ju XIA tian ZHONG liang-bao Department of Nephrology State key Laboratory of Kidney Disease Chinese PLA General Hospital Beijing 100853 China Nephrology Institute of the Chinese People's Liberation Army Chinese People's Liberation Army Key Laboratory of Nephrology Beijing 100853 China Department of Nephrology West China Hospital of Sichuan University Chengdu Sichuan 610041 China Department of Nephrology First Affiliated Hospital School of Medicine Zhejiang University Hangzhou Zhejiang 310003 China Department of Nephrology Zhongshan Hospital Fudan University Shanghai 200032 China Department of Nephrology First Affiiated Hospital of Sun Yat-sen University Guangzhou Guangdong 510080 China Department of Nephrology First Affiliated Hospital of Dalian Medical University Dalian Liaoning 116011 China Department of Nephrology First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China Department of Nephrology First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 China Department of Nephrology First Afftiated Hospital of China Medical University Shenyang Liaoning 110001 China Department of Nephrology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200025 China Department of Nephrology Second Xiangya Hospital Central South University Changsha Hunan 410000 China Department of Nephrology First Affiliated Hospital of Medical College Xi'an Jiaotong University Xi'an Shaanxi 710061 China Department of Nephrology First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital) Nanjing Jiangsu 210029 China Department of Nephrology Sichuan Provincial People's Hospital Chengdu Sichuan 610072 China Department of Nephrology Guangdong Provincial People's Hospital Guangzhou Guangdong 510030 China Department of Nephrology Affliated Xiehe Hospital Tongji Medical College Huazhong Science and Technology University Wuhan Hubei 430022 China Department of Nephrology Daping Hospital Third Military Medi

Background data on the epidemiology of hypertension in Chinese non-dialysis chronic kidney disease （CKD） patients are *** aim of the present study was to investigate the prevalence,awareness,treatment,and control of hypertension in the non-dialysis CKD patients through a nationwide,multicenter study in *** The survey was performed in 61 tertiary hospitals in 31 provinces,municipalities,and autonomous regions in China （except Hong Kong,Macao,and Taiwan）.Trained physicians collected demographic and clinical data and measured blood pressure （BP） using a standardized *** was defned as systolic BP ≥140 mmHg and/or diastolic BP ≥90 mmHg,and/or use of antihypertensive *** 〈140/90 mmHg and 〈130/80 mmHg were used as the 2 thresholds of hypertension *** multivariate logistic regression with adjustment for sex and age,we analyzed the association between CKD stages and uncontrolled hypertension in non-dialysis CKD *** The analysis included 8927 non-dialysis CKD *** prevalence,awareness,and treatment of hypertension in non-dialysis CKD patients were 67.3%,85.8%,and 81.0%,*** hypertensive CKD patients,33.1% and 14.1% had controlled BP to 〈140/90 mmHg and 〈130/80 mmHg,*** successive CKD stages,the prevalence of hypertension in non-dialysis CKD patients increased,but the control of hypertension decreased （P〈0.001）.When the threshold of BP 〈130/80 mmHg was considered,the risk of uncontrolled hypertension in CKD 2,3a,3b,4,and 5 stages increased 1.3,1.4,1.4,2.5,and 4.0 times compared with CKD 1 stage,respectively （P〈0.05）.Using the threshold of 〈140/90 mmHg,the risk of uncontrolled hypertension increased in advanced stages （P〈0.05）.Conclusions The prevalence of hypertension Chinese non-dialysis CKD patients was high,and the hypertension control was *** successive CKD stages,the risk of uncontrolled hypertension increased.

关键词： non-dialysis chronic kidney disease chronic kidney disease stages hypertension epidemiology

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Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin liu yue huang Guang-cheng Xiao qing-Cui Bu jin-lu Qu Shu Zhang Shuang-Nan Zhang Shu-Mei Jia Fang-jun lu Xiang Ma lian Tao Wei Zhang Li chen Li-Ming Song Ti-Pei Li Yu-Peng Xu Xue-Lei Cao Yong chen Cong-Zhan liu Ce Cai zhi chang Gang chen tian-Xiang chen Yi-Bao chen Yu-Peng chen Wei Cui Wei-Wei Cui jing-Kang Deng Yong-Wei Dong Yuan-Yuan Du Min-Xue fu Guan-hua Gao He Gao Min Gao Ming-Yu Ge Yu-Dong Gu Ju Guan cheng-cheng guo da-Wei Han Jia Huo lu-hua Jiang Wei-Chun Jiang jing jin Yong-Jie jin Ling-da Kong Bing Li cheng-Kui Li Gang Li Mao-Shun Li Wei Li Xian Li Xiao-Bo Li Xu-Fang Li Yang-guo Li Zheng-Wei Li Xiao-hua liang jing-Yuan Liao Bai-Sheng liu guo-qing liu Hong-Wei liu Xiao-jing liu Yi-Nong liu Bo lu Xue-feng lu Qi luo Tao luo Bin Meng Yi Nang Jian-Yin Nie Ge Ou Na Sai Ren-cheng Shang Xin-Ying Song liang sun Ying Tan You-Li Tuo chen wang guo-feng wang Juan wang Ling-jun wang Weng-Shuai wang Yu-Sa wang Xiang-Yang Wen Bai-Yang Wu Bo-Bing Wu Mei Wu Shuo Xiao Shao-Lin Xiong He Xu Jia-Wei Yang Sheng Yang Yan-Ji Yang Yi-jung Yang Qi-Bin Yi Qian-qing Yin Yuan You Ai-Mei Zhang cheng-Mo Zhang Fan Zhang Hong-Mei Zhang Juan Zhang Tong Zhang Wan-chang Zhang Wen-Zhao Zhang Yi Zhang Yi-Fei Zhang Yong-Jie Zhang Yuan-Hang Zhang yue Zhang Zhao Zhang zhi Zhang Zi-liang Zhang Hai-Sheng Zhao Xiao-Fan Zhao Shi-Jie Zheng Yao-Guang Zheng Deng-Ke Zhou Jian-feng Zhou Yu-Xuan Zhu Ren-Lin Zhuang yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

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光学相干断层成像与血管内超声评价冠状动脉斑块的病理对照研究

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中华心血管病杂志 2012年第4期40卷 302-306页

作者：郭军孙璐陈韵岱田峰刘宏斌陈练孙志军任艺虹金琴花刘长福韩宝石盖鲁粤杨庭树解放军总医院心内科北京100853 解放军总医院病理科北京100853

目的以尸检冠状动脉的病理诊断为对照，比较光学相干断层成像（OCT）与血管内超声（IVUS）识别及评价不同类型斑块的准确性。方法对15例尸检心脏的冠状动脉先行OCT和IVUS检查，然后制作病理切片。依据OCT和IVUS的判别标准将斑块分为3类... 详细信息

目的以尸检冠状动脉的病理诊断为对照，比较光学相干断层成像（OCT）与血管内超声（IVUS）识别及评价不同类型斑块的准确性。方法对15例尸检心脏的冠状动脉先行OCT和IVUS检查，然后制作病理切片。依据OCT和IVUS的判别标准将斑块分为3类：脂质斑块、钙化斑块和纤维斑块。以病理诊断为对照，比较OCT与IVUS识别不同类型斑块的敏感性和特异性。结果总共对77个冠状动脉斑块进行了分析。OCT识别脂质斑块、钙化斑块和纤维斑块的敏感性分别为69％、93％和88％，特异性分别为88％、92％和98％；IVUS识别脂质斑块、钙化斑块和纤维斑块的敏感性分别为6l％、98％和68％，特异性分别为92％、97％和90％。OCT与IVUS识别不同斑块的符合率为0．831（Kappa值=0．72，P〈0．01）。结论OCT和IVUS对不同类型斑块的识别有较好的准确性和一致性，而且OCT对纤维斑块的识别优于IVUS，对钙化斑块的识别并不优于IVUS。

关键词：体层摄影术,光学相干超声检查,介入性动脉粥样硬化

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