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W^(m,p(t,x))-Estimate for a Class of Higher-Order Parabolic Equations with Partially BMO Coefficients

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Journal of Partial Differential Equations 2024年第2期37卷 198-234页

作者： tian hong HAO Shuai ZHENG Shenzhou College of Science Tianjin University of TechnologyTianjin 300384China Department of Mathematics Beijing Jiaotong UniversityBeijing 100044China

We prove a global estimate in the Sobolev spaces with variable exponents to the solution of a class of higher-order divergence parabolic equations with measurable coefficients over the non-smooth ***,it is mainly assumed that the coefficients are allowed to be merely measurable in one of the spatial variables and have a small BMO quasi-norm in the other variables at a sufficiently small scale,while the boundary of the underlying domain belongs to the so-called Reifenberg *** is a natural outgrowth of Dong-Kim-Zhang’s papers[1,2]from the W^(m,p)-regularity to the W^(m,p(t,x))-regularity for such higher-order parabolic equations with merely measurable coefficients with Reifenberg flat domain which is beyond the Lipschitz domain with small Lipschitz constant.

关键词： A higher-order parabolic equation Sobolev spaces with variable exponents partially BMO quasi-norm Reifenberg flat domains log-Hölder continuity

On-spot preparation of EDTA solution for the treatment of band keratopathy:a case report

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 767-769页

作者： Yan-Ting Li Bin Chen tian-hong Wu Bo Jiang Yun-Feng Lu Department of Ophthalmology the First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina Department of Ophthalmology Suzhou EENT HospitalSuzhou 215000Jiangsu ProvinceChina

Dear Editor,We report a case of band keratopathy who experienced several ocular surgeries,secondary uveitis and glaucoma which eventually led to severe band *** use commonly-used vacuum blood collection tubes with ethylenediaminetetraacetic acid dipotassium salt(EDTA-K2)to prepare chelation solution on-spot to remove the calcium deposits on the corneal *** is proved to be relatively safety,efficacy,cost-effective.

关键词： glaucoma eventually preparation

Pars plana vitrectomy with internal limiting membrane plugging assisted by autologous blood for optic disc pit associated with vitreomacular traction

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1957-1959页

作者： Bin Chen Yan-Ting Li tian-hong Wu Ya-Ping Yuan Yun-Feng Lu Department of Ophthalmology Suzhou EENT HospitalSuzhou 215000Jiangsu ProvinceChina Department of Ophthalmology the First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

Dear Editor,We report a case of optic disc pit(ODP)associated with vitreomacular traction which has been successfully treated by a combined *** have obtained the written informed consent from the patient,and this case... 详细信息

关键词： technique. traction macular

Analysis of the Development Trend of Ideological and Political Education in Experimental Courses in Colleges and Universities:Visual Analysis Based on CiteSpace

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Journal of Contemporary Educational Research 2024年第4期8卷 241-246页

作者： hong tian Liquan Sun Hao Gu School of Life Science Beijing Institute of TechnologyBeijing 100081China

In order to deeply understand the status of ideological and political research on experimental courses in colleges and universities,the relevant literature collected by China National Knowledge Infrastructure(CNKI)was taken as the research object,and the analysis was carried out by using CiteSpace *** results show that research authors of ideological and political education in experimental courses have not yet formed cross-regional cooperation,and there is no core *** ideological and political construction of experimental courses mainly focuses on experimental courses such as medicine,chemistry,and *** research focus on ideological and political education in experimental courses focuses on the concept of educating people,the construction of teaching systems,teaching modes,and the combination of new experimental teaching methods and ideological and political *** ideological and political education of experimental courses needs more attention and support from colleges and universities.

关键词： Ideological and political education Experimental course CiteSpace Visualization Bibliometrics

Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2716-2725页

作者： tian hong Qinghua Luo Haiyun Ma Xin Wang Xinqiong Li Chongrong Shen Jie Pang Yan Wang Yuejia Chen Changbin Zhang Zhaoming Su Haohao Dong Xiaodi Tang Department of Laboratory Medicine State Key Laboratory of BiotherapyNational Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengduChina Frontiers Medical Center Tianfu Jincheng LaboratoryWest China HospitalSichuan UniversityChengduChina

CRISPR‒Cas7-11 is a Type Ⅲ-E CRISPR-associated nuclease that functions as a potent RNA editing ***-peptide repeat fused with Cas/HEF1-associated signal transducer(TPR-CHAT)acts as a regulatory protein that interacts with CRISPR RNA(crRNA)-bound Cas7-11 to form a CRISPR-guided caspase complex(Craspase).However,the precise modulation of Cas7-11’s nuclease activity by TPR-CHAT to enhance its utility requires further ***,we report cryo-electron microscopy(cryo-EM)structures of Desulfonema ishimotonii(Di)Cas7-11-crRNA,complexed with or without the full length or the N-terminus of *** structures unveil the molecular features of the Craspase *** analysis,combined with in vitro nuclease assay and electrophoretic mobility shift assay,reveals that DiTPR-CHAT negatively regulates the activity of DiCas7-11 by preventing target RNA from binding through the N-terminal 65 amino acids of DiTPR-CHAT(DiTPR-CHAT_(NTD)).Our work demonstrates that DiTPRCHAT_(NTD) can function as a small unit of DiCas7-11 regulator,potentially enabling safe applications to prevent overcutting and offtarget effects of the CRISPR‒Cas7-11 system.

关键词： CRISPR crRNA TPR

Leading Pattern of Spring Drought Variability over East Asia and Associated Drivers

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Journal of Tropical Meteorology 2024年第1期30卷 1-10页

作者：赵庆红杨崧田红瑛邓开强 School of Atmospheric Sciences Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)ZhuhaiGuangdong 519082 China Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies Sun Yat-sen UniversityZhuhaiGuangdong 519082 China College of Atmospheric Sciences Lanzhou UniversityLanzhou 730000 China

Drought events have become more frequent and intense over East Asia in recent decades,leading to huge socioeconomic *** the droughts have been studied extensively by cases or for individual regions,their leading variability and associated causes remain *** on the Standardized Precipitation Evapotranspiration Index(SPEI)and ERA5 reanalysis product from 1979 to 2020,this study evealuates the severity of spring droughts in East Asia and investigates their variations and associated *** results indicate that North China and Mongolia have experienced remarkable trends toward dryness during spring in recent decades,while southwestern China has witnessed an opposite trend toward *** first Empirical Orthogonal Function mode of SPEI variability reveals a similar seesawing pattern,with more severe dryness in northwestern China,Mongolia,North China,South Korea,and Japan but increased wetness in Southwestern China and southeast *** investigation reveals that the anomalously dry(wet)surface in North(Southwestern)China is significantly associated with anomalously high(low)temperature,less(more)precipitation,and reduced(increased)soil moisture during the previous winter and early spring,regulated by an anomalous anticyclone(cyclone)and thus reduced(increased)water vapor *** spring dry-wet pattern in East Asia is also linked to cold sea surface temperature anomalies in the central-eastern *** findings of this study have important implications for improving the prediction of spring drought events in East Asia.

关键词： drought leading pattern East Asia spring drivers

Plume-lithosphere interaction in the Comei Large Igneous Province: Evidence from two types of mafic dykes in Gyangze, south Tibet, China

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China Geology 2024年第1期7卷 80-90页

作者： Ya-ying Wang Ling-sen Zeng Li-e Gao Li-long Yan Ling-hao Zhao Jia-hao Gao Ying-long Di Guang-xu Li Yi-hong tian Institute of Geology Chinese Academy of Geological SciencesBeijing 100037China National Research Center for Geoanalysis Chinese Academy of Geological SciencesBeijing 100037China China Nonferrous Metals(Guilin)Geology and Mining Co. LtdGuilin 541004China

Two suites of mafic dykes,T1193-A and T1194-A,outcrop in Gyangze area,southeast *** are in the area of Comei LIP and have indistinguishable field occurrences with two other dykes in Gyangze,T0902 dyke with 137.7±1.3 Ma zircon age and T0907 dyke with 142±1.4 Ma zircon age reported by Wang YY et al.(2016),indicating coeval formation *** all the four diabase dykes into consideration,two different types,OIB-type and weak enriched-type,can be ***“OIB-type”samples,including T1193-A and T0907 dykes,show OIB-like geochemical features and have initial Sr-Nd isotopic values similar with most mafic products in Comei Large Igneous Provinces(LIP),suggesting that they represent melts directly generated from the Kerguelen mantle ***“weak enriched-type”samples,including T1194-A and T0902 dykes,have REEs and trace element patterns showing withinplate affinity but have obvious Nb-Ta-Ti negative *** show uniform lowerεNd(t)values(−6‒−2)and higher 87Sr/86Sr(t)values(0.706‒0.709)independent of their MgO variation,indicating one enriched mantle *** their closely spatial and temporal relationship with the widespread Comei LIP magmatic products in Tethyan Himalaya,these“weak enriched-type”samples are consistent with mixing of melts from mantle plume and the above ancient Tethyan Himalaya subcontinental lithospheric mantle(SCLM)in different *** weak enriched mafic rocks in Comei LIP form one special rock group and most likely suggest large scale hot mantle plume-continental lithosphere *** process may lead to strong modification of the Tethyan Himalaya lithosphere in the Early Cretaceous.

关键词： OIB type diabase Comei Large Igneous Province Weakly enriched diabase Plume-lithosphere interaction Nb-Ta-Ti negative anomaly Kerguelen plume Geological survey engineering Tibet Plateau

基于动力学分析的汽车减震器示功图故障检测算法

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吉林大学学报（工学版） 2024年第5期54卷 1221-1226页

作者：关亮亮田国红辽宁工业大学汽车与交通工程学院辽宁锦州121001

为解决汽车减震器因流动惯量导致径向动力发生偏差的问题,提出基于动力学分析的汽车减震器示功图故障检测算法。计算减震液在左、右2个封闭区域的流动惯量,将压缩行程中的径向动力和回弹行程中的径向动力代入能量与动量方程中,建立汽车... 详细信息

为解决汽车减震器因流动惯量导致径向动力发生偏差的问题,提出基于动力学分析的汽车减震器示功图故障检测算法。计算减震液在左、右2个封闭区域的流动惯量,将压缩行程中的径向动力和回弹行程中的径向动力代入能量与动量方程中,建立汽车减震器动力学方程,再绘制实测示功图,并将其作为样本输入支持向量机中进行分类,再设定判定阈值进行阈值判定,完成示功图故障检测。试验结果表明:本文方法在供液不足、双凡尔漏失、活塞被卡、砂阻时获取的汽车减震器示功图与实测示功图基本吻合,说明本文方法的故障检测准确性高。

关键词：动力学分析汽车减震器连杆示功图支持向量机

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中国旅游业高质量发展水平的测度与评估

江西财经大学学报 2024年第1期 37-53页

作者：田红刘呈庆山东师范大学经济学院山东济南250014 山东师范大学《中国人口·资源与环境》编辑部山东济南250014

旅游业高质量发展是推进中国式现代化的重要基础和有力支撑,科学测度和评价区域旅游业高质量发展水平及其变化趋势具有重要的理论和现实意义。在界定旅游业高质量发展内涵的基础上,以新发展理念和可持续发展理论为指导,构建旅游业高质... 详细信息

旅游业高质量发展是推进中国式现代化的重要基础和有力支撑,科学测度和评价区域旅游业高质量发展水平及其变化趋势具有重要的理论和现实意义。在界定旅游业高质量发展内涵的基础上,以新发展理念和可持续发展理论为指导,构建旅游业高质量发展评价指标体系,并对中国30个省份的旅游业高质量发展水平进行测度与评估。研究表明:2011—2019年中国旅游业高质量发展水平总体呈现逐年上升趋势,产业发展水平、社会和谐水平、创新能力、文旅融合程度、生态保护水平均得到明显提升,2020—2021年受新型冠状病毒感染疫情影响,虽然总体发展水平和产业发展水平有所下降,但其他四大指标得分均持续上升,反映了中国旅游业高质量发展水平随着我国高质量发展进程而不断提升。但是各省份之间旅游业高质量发展水平差异明显,总体发展质量处于中等水平,距离高质量发展标准仍有较大差距。未来提升旅游业高质量发展水平应重点从优化产业结构、提高旅游创新质量、深化文旅融合、加强生态保护等方面入手。

关键词：旅游业高质量发展指标体系熵值法