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Systematized Literature Review on Spatial Analysis of Environmental Risk Factors of Malaria Transmission

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Advances in Infectious Diseases 2016年第2期6卷 52-62页

作者： tiago Canelas Carlos Castillo-Salgado Helena Ribeiro School of Public Health University of Sao Paulo Sao Paulo Brazil Johns Hopkins Bloomberg School of Public Health Baltimore US Global Public Health Observatory Johns Hopkins Bloomberg School of Public Health Baltimore US

Malaria is still the major parasitic disease in the world, with approximately 438,000 deaths in 2015. Environmental risk factors (ERF) have been widely studied, however, there are discrepancies in the results about their influence on malaria transmission. Recently, papers have been published about geospatial analysis of ERF of malaria to explain why malaria varies from place to place. Our primary objective was to identify the environmental variables most used in the geospatial analysis of malaria transmission. The secondary objective was to identify the geo-analytic methods and techniques, as well as geo-analytic statistics commonly related to ERF and malaria. We conducted a systematized review of articles published from January 2004 to March 2015, within Web of Science, Pubmed and LILACS databases. Initially 676 articles were found, after inclusion and exclusion criteria, 29 manuscripts were selected. Temperature, land use and land cover, surface moisture and vector breeding site were the most frequent included variables. As for geo-analytic methods, geostatistical models with Bayesian framework were the most applied. Kriging interpolations, Geographical Weighted Regression as well as Kulldorff’s spatial scan were the techniques more widely used. The main objective of many of these studies was to use these methods and techniques to create malaria risk maps. Spatial analysis performed with satellite images and georeferenced data are increasing in relevance due to the use of remote sensing and Geographic Information System. The combination of these new technologies identifies ERF more accurately, and the use of Bayesian geostatistical models allows a wide diffusion of malaria risk maps. It is known that temperature, humidity vegetation and vector breeding site play a critical role in malaria transmission;however, other environmental risk factors have also been identified. Risk maps have a tremendous potential to enhance the effectiveness of malaria-control programs.

关键词： Malaria Spatial Analysis Environmental Risk Factors Malaria Transmission Malaria Determinants

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植酸盐-猪、禽饲料的抗营养成分

中国畜牧杂志 2012年第8期48卷 42-43,46页

作者： tiago Santos 傅钰

菲汀（phytin）是肌醇六磷酸与钙、镁等金属离子形成的复盐。在动物营养学上，常称之为植酸盐（phytate），是种子中贮存磷元素的主要形式。植酸盐起初被认为是种子萌发的磷源，现在普遍认为，植酸盐于种子萌发时期在防止氧化应激、减... 详细信息

菲汀（phytin）是肌醇六磷酸与钙、镁等金属离子形成的复盐。在动物营养学上，常称之为植酸盐（phytate），是种子中贮存磷元素的主要形式。植酸盐起初被认为是种子萌发的磷源，现在普遍认为，植酸盐于种子萌发时期在防止氧化应激、减少胚胎的死亡方面发挥重要作用。这可能与植酸可以螯合铁、钙、锌等矿质元素有关。

关键词：植酸盐抗营养成分禽饲料种子萌发肌醇六磷酸动物营养学金属离子氧化应激

Pseudomelanosis duodeni associated with chronic renal failure

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World Journal of Gastroenterology 2012年第12期18卷 1414-1416页

作者： Marcia Henriques de Magalhes Costa Maria da Gloria Fernandes Pegado Cleber Vargas Maria Elizabeth C Castro Kalil Madi tiago Nunes Cyrla Zaltman Gastroenterology Section Department of Internal MedicineClementino Fraga Filho University HospitalUniversidade Federal do Rio de JaneiroRio de Janeiro 21941-913Brazil Department of Pathology Clementino Fraga Filho University HospitalUniversidade Federal do Rio de JaneiroRio de Janeiro 21941-913Brazil Hospital Clínic i Provincial/IDIBAPS Barcelona 08036Spain

Pseudomelanosis duodeni (PD) is a rare dark speckled appearance of the duodenum associated with gastrointestinal bleeding,hypertension,chronic heart failure,chronic renal failure and consumption of different *** report four cases of PD associated with chronic renal failure admitted to the gastroenterology outpatient unit due to epigastric pain,nausea,melena and progressive reduction of hemoglobin *** endoscopy revealed erosions in the esophagus and stomach,with no active bleeding at the *** addition,the duodenal mucosa presented marked signs of melanosis;later confirmed by histopathological *** though PD is usually regarded as a benign condition,its pathogenesis and clinical significance is yet to be defined.

关键词： Pseudomelanosis duodeni Chronic renal fail-ure Diabetes mellitus Anti hypertensive drugs Gastro-duodenal endoscopy

Intimate partner violence against women. Does violence decrease after the entry of the alleged offender into the criminal justice system?

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Forensic Sciences Research 2022年第1期7卷 53-60页

作者： Paulo Vieira-Pinto JoséIgnacio Muñoz-Barús tiago Taveira-Gomes Maria João Vidal-Alves Teresa Magalhães Department of Forensic Sciences PathologyGynaecology and ObstetricsPaediatricsInstitute of Forensic SciencesUniversity of Santiago de CompostelaSantiago de CompostelaSpain IINFAC TS-Institute of Research and Advanced Training in Health Sciences Department of SciencesCESPUUniversity Institute of Health Sciences(IUCS)GandraPortugal cFaculty of Medicine University of PortoPortoPortugal CINTESIS-Centre of Health Technology and Service Research University of PortoPortoPortugal Fernando Pessoa University PortoPortugal

Intimate partner violence(IPV)is simultaneously assumed as a serious crime and a major public health issue,having recurrences as one of its main characteristics and,consequently,re-entries of some alleged offenders in the criminal justice system(CJS).The main goal of this study is to assess if in cases of female victims of IPV,violence decreases after the first entry of the alleged offender in the CJS.A retrospective study was performed based on the analysis of police reports of alleged cases of IPV during a 4-year *** final sample(n=1488)was divided into two groups according to the number of entries in the CJS(single or multiple)followed by a comparative *** suggest that violence decreases after the first entry of alleged offenders in the ***-entries were found in only 15.5%of the cases but they were accountable for 3.3 times more crimes on ***,victims of recidivism presented more injuries and required more medical ***,a small group of alleged offenders seems to be more violent and accountable for most of the IPV crimes registered in the CJS suggesting that regardless of legal sanctions aiming to deter violence,these measures may not be enough for a certain group of *** study sustains the need for a predictive model to quantify the risk of repeated IPV cases within the Portuguese population.

关键词： Forensic sciences intimate partner violence women re-entry recidivism criminal justice system

Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling

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Signal Transduction and Targeted Therapy 2023年第11期8卷 5404-5416页

作者： Catarina Macedo-Silva Vera Miranda-Gonçalves Nuno tiago Tavares Daniela Barros-Silva Joana Lencart João Lobo Ângelo Oliveira Margareta PCorreia Lucia Altucci Carmen Jerónimo Cancer Biology&Epigenetics Group Research Center of IPO Porto(CI-IPOP)/CI-IPOP@RISE(Health Research Network)Portuguese Oncology Institute of Porto(IPO-Porto)/Porto Comprehensive Cancer Center Raquel Seruca(Porto.CCC)R.Dr.António Bernardino de Almeida4200-072PortoPortugal Department of Precision Medicine University of Campania“Luigi Vanvitelli”80138NaplesItaly Department of Pathology and Molecular Immunology ICBAS-School of Medicine&Biomedical SciencesUniversity of PortoR.Jorge de Viterbo Ferreira 2284050-313PortoPortugal Medical Physics Radiobiology and Radiation Protection Group-Research Center of IPO Porto(CI-IPOP)/CI-IPOP@RISE(Health Research Network)Portuguese Oncology Institute of Porto(IPO-Porto)/Porto Comprehensive Cancer Center Raquel Seruca(Porto.CCC)R.Dr.António Bernardino de Almeida4200-072PortoPortugal Department of Medical Physics Portuguese Oncology Institute of Porto4200-072PortoPortugal Department of Pathology Portuguese Oncology Institute of PortoPortoPortugal Department of Radiation Oncology Portuguese Oncology Institute of PortoPortoPortugal BIOGEM Molecular Biology and Genetics Research Institute83100AvellinoItaly IEOS Institute of Endocrinology and Oncology80100NaplesItaly

External beam radiotherapy(RT)is a leading first-line therapy for prostate cancer(PCa),and,in recent years,significant advances have been ***,RT resistance can arise and result in long-term recurrence or disease progression in the worst-case ***,making crucial the discovery of new targets for PCa ***,we generated a radioresistant PCa cell line,and found p53 to be highly expressed in radioresistant PCa cells,as well as in PCa patients with recurrent/disease progression submitted to *** dissection revealed that RT could promote p53 expression via epigenetic ***,a decrease of H3K27me3 occupancy at TP53 gene promoter,due to increased KDM6B activity,was observed in radioresistant PCa ***,p53 is essential for efficient DNA damage signaling response and cell recovery upon stress induction by prolonged fractionated ***,KDM6B inhibition by GSK-J4 significantly decreased p53 expression,consequently attenuating the radioresistant phenotype of PCa cells and hampering in vivo 3D tumor ***,this work contributes to improve the understanding of p53 as a mediator of signaling transduction in DNA damage repair,as well as the impact of epigenetic targeting for PCa radiosensitization.

关键词： TP53 damage cancer

Xylanase, protease and superdosing phytase interactions in broiler performance, carcass yield and digesta transit time

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Animal Nutrition 2017年第2期3卷 121-126页

作者： tiago T.dos Santos Helen V.Masey O'Neill Gemma González-Ortiz Daniel Camacho-Fernández Carlos López-Coello AB Vista Facultad de Medicina Veteriaria y Zootecnia Universidad Nacional Autónoma de México

The interaction of xylanase, protease and superdosing(1,500 FTU/kg) phytase in a 2×2×2 factorial arrangement was studied in broilers fed sorghum-based diets. A total of 2,800 one-day-old unsexed Ross308 chicks were housed in 56 pens with 50 birds per pen, with or without inclusion of xylanase, protease and phytase, totaling 8 treatments and 7 replicates per treatment. Body weight(BW) and feed intake(FI)were measured at 21 and 42 days of age, and mortality corrected feed conversion ratio(FCR) was calculated for each period and cumulatively. Tibia ash and carcass yield were determined in 2 birds per replicate at 21 and 42 days of age, respectively. Digesta transit time was determined at 21, 28, 35 and 42 days of age using 5 birds per replicate. Results showed that superdosing phytase increased BW and FI at42 days of age(P < 0.05) and xylanase improved FCR(P < 0.05). Xylanase and phytase also positively influenced carcass yield and breast weight, respectively. Overall, inclusion of superdosing phytase increased transit time when included in a diet containing xylanase, and no change with protease inclusion. In conclusion, the beneficial effects of xylanase, protease and superdosing phytase in broiler performance were not additive. This limitation is likely not related to the lack of efficacy of any one of the individual enzymes but to a limitation of the bird to respond additively to successive additions of enzymes.

关键词： Sorghum Tibia ash Sub-additivity Exogenous enzyme

Fast Fading Channel Neural Equalization Using Levenberg-Marquardt Training Algorithm and Pulse Shaping Filters

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International Journal of Communications, Network and System Sciences 2014年第2期7卷 71-74页

作者： tiago Mota Jorgean Leal Antonio Lima Departament of Mechatronics Federal University of BahiaBahiaBrazil National Telecommunications Agency of Brazil BahiaBrazil Departament of Electrical Engineering Federal University of BahiaBahiaBrazil

Artificial Neural Network (ANN) equalizers have been successfully applied to mitigate Inter symbolic Interference (ISI) due to distortions introduced by linear or nonlinear communication channels. The ANN architecture is chosen according to the type of ISI produced by fixed, fast or slow fading channels. In this work, we propose a combination of two techniques in order to minimize ISI yield by fast fading channels, i.e., pulse shape filtering and ANN equalizer. Levenberg-Marquardt algorithm is used to update the synaptic weights of an ANN comprise only by two recurrent perceptrons. The proposed system outperformed more complex structures such as those based on Kalman filtering approach.

关键词： Decision Feedback Equalizers Levenberg-Marquardt Algorithm Pulse Shaping Recurrent Neural Networks

The Use of Data Mining Techniques in Rockburst Risk Assessment

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Engineering 2017年第4期3卷 552-558页

作者： Luis Ribeiro e Sousa tiago Miranda Rita Leal e Sousa Joaquim Tinoco State Key Laboratory for GeoMechanics and Deep Underground Engineering China University of Mining and Technology (Beijing) Beijing 100083 China Institute for Sustainability and Innovation in Structural Engineering Department of Civil Engineering University of Minho Campus de Azurem Guimaraes 4800-058 Portugal Masdar Institute of Science and Technology Musdar City Abu Dhabi UAE

Rockburst is an important phenomenon that has affected many deep underground mines around the world. An understanding of this phenomenon is relevant to the management of such events, which can lead to saving both costs and lives. Laboratory experiments are one way to obtain a deeper and better understanding of the mechanisms of rockburst. In a previous study by these authors, a database of rockburst laboratory tests was created; in addition, with the use of data mining （DM） techniques, models to predict rockburst maximum stress and rockburst risk indexes were developed. In this paper, we focus on the analysis of a database of in situ cases of rockburst in order to build influence diagrams, list the factors that interact in the occurrence of rockburst, and understand the relationships between these factors. The in situ rockburst database was further analyzed using different DM techniques ranging from artificial neural networks （ANNs） to naive Bayesian classifiers. The aim was to predict the type of rockburst-that is, the rockburst level-based on geologic and construction characteristics of the mine or tunnel. Conclusions are drawn at the end of the paper.

关键词： Rockburst Data mining Bayesian networks In situ database

酒店管理信息系统建设研究——以佛得角酒店信息化为例

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酒店管理信息系统建设研究——以佛得角酒店信息化为例

作者： tiago Coutinho（蒂亚哥）天津大学

学位级别：硕士

随着全球数字化经济的蓬勃发展,酒店行业也迎来了新的机遇和挑战,信息化建设将进一步赋能酒店行业的转型升级。作为拥有丰富海滩资源和文化遗产资源的国家,佛得角的酒店旅游业已经成为国民经济的重要支柱型产业。在数字化时代,其酒店行... 详细信息

随着全球数字化经济的蓬勃发展,酒店行业也迎来了新的机遇和挑战,信息化建设将进一步赋能酒店行业的转型升级。作为拥有丰富海滩资源和文化遗产资源的国家,佛得角的酒店旅游业已经成为国民经济的重要支柱型产业。在数字化时代,其酒店行业迫切需要在传统信息化建设的基础上,持续优化信息流管理,提高酒店数字化运营水平。本文运用比较分析法和调查研究法,详细阐述了信息化与数字化建设对酒店经营管理的重要作用,并以预定、住宿、餐饮、休闲和娱乐活动等酒店主要业务领域作为研究的重点,深入分析了酒店在经营过程中管理信息系统的整体建设情况及信息流在各个业务领域的具体应用,研究揭示了即时信息流的有效处理和各部门之间的信息协同整合对于酒店最优化决策至关重要。在此基础上,本文总结了当地酒店在信息化建设方面存在的主要问题,并提出对酒店信息流优化改进的措施和建议,尤其是各部门之间以及与酒店外部进行及时有效的信息流整合,旨在更好地改善和提升服务水平,提供更优质的服务体验,从而有效增加酒店预订量,提高酒店在数字化时代的核心竞争力。

关键词：酒店业信息管理知识管理信息流旅游业