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Occurrence, distribution and risk assessment of antibiotics at various aquaculture stages in typical aquaculture areas surrounding the Yellow Sea

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Journal of Environmental Sciences 2023年第4期126卷 621-632页

作者： Jiachao Zhang Xuanrui Zhang Yang Zhou Qianfan Han Xiaoli Wang chao Song Shuguang Wang shan Zhao shandong Key Laboratory of Water Pollution Control and Resource Reuse School of Environmental Science and EngineeringShandong UniversityQingdao 266237China Water Science and Environmental Engineering Research Center College of Chemical and Environmental EngineeringShenzhen UniversityShenzhen 518060China Qingdao Municipal Bureau of Ecology and Environment Qingdao 266003China Analysis and Test Center Qilu University of Technology(Shandong Academy of Sciences)Jinan 250014China

The pollution of antibiotics commonly existed throughout the entire aquaculture process,but the residues of antibiotics at different aquaculture stages have rarely been *** study investigated the occurrence,distribution and risk assessment of antibiotics at different aquaculture stages (the non-aquaculture stage,the early aquaculture stage,the middle aquaculture stage,and the late aquaculture stage) in two typical marine aquaculture areas(Mahegang River and Dingzi Bay) surrounding the Yellow *** and tetracyclines were commonly used antibiotics in the aquaculture of these areas with high detection frequencies (17%to 83%).Compared among four aquaculture stages,the highest concentration of antibiotics (9032.08 ng/L) in aquaculture ponds was detected at the late aquaculture *** the antibiotic pollution level of natural water was directly related to the aquaculture ***,at the aquaculture stages,the detection frequency of antibiotics in sediments was higher than that at the non-aquaculture *** on the correlation analysis,the concentration of main antibiotics in water showed a positive correlation with total nitrogen (ptive correlation with salinity (ption pressure of fluoroquinolones and tetracyclines on resistant bacteria had *** the ecological risks caused by sulfonamides and tetracyclines to aquatic organisms had also increased ***,this study may provide a reference for formulating regulatory policies regarding antibiotic use at different aquaculture stages.

关键词： Antibiotics Aquaculture stages Correlation analysis Risk assessment

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Effect of biochar on grain yield and leaf photosynthetic physiology of soybean cultivars with different phosphorus efficiencies

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Journal of Integrative Agriculture 2019年第10期18卷 2242-2254页

作者： ZHU Qian KONG Ling-jian shan Yu-zi YAO Xing-dong ZHANG Hui-jun XIE Fu-ti AO Xue Soybean Research Institute Agronomy College Shenyang Agricultural University

This study was conducted with two soybean cultivars, Liaodou 13 (L13, phosphorus (P)-efficient) and tiefeng 3 (T3, P-inefficient), to investigate the effects of biochar on soybean yield and photosynthetic physiological parameters, at four biochar application rates (0, 1, 5, and 10%, w/w), and two fertilization treatments (0 and 150 kg ha–1). Grain yield, plant biomass, P accumulation, leaf net photosynthetic rate (Pn), chlorophyll index (Chl), nitrogen balance index (NBI), sucrose phosphate synthase (SPS), and sucrose synthase (SS) activities, soluble sugar, sucrose and starch contents, and leaf area duration (LAD) were measured. Biochar had positive effects on Pn, Chl, NBI, SPS, and SS activities, and leaf soluble sugar, sucrose, and starch contents of both genotypes, these effects increased with biochar application rate. L13 benefited more efficiently from biochar than T3 did, as the grain yield of L13 significantly increased by 31.0 and 51.0%, at 5 and 10% biochar, respectively, while that of T3 increased by 40.4 at 10% biochar application rate, as compared with controls. The combined application of biochar and fertilizer boosted the positive effects described, but no difference was found for grain yield in L13 among biochar application rates, while grain yield of T3 continually increased with biochar rate, among which, 1% biochar combined with 150 kg ha–1 fertilizer resulted in T3 yield increment of more than 23%, compared with the application of 150 kg ha–1 fertilizer alone. Altogether, our results indicated that the application of biochar enhanced carbon assimilation in soybean, resulting in increased biomass accumulation and yield. Differences in genotypic responses to biochar highlight the need to consider specific cultivars and biochar rate, when evaluating the potential responses of crops to biochar.

关键词： biochar P efficiency photosynthesis soybean yield

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Evolution of microstructure and hardness in a dual-phase Al0.5CoCrFeNi high-entropy alloy with different grain sizes

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Rare Metals 2020年第2期39卷 156-161页

作者： Hao-Xue Yang Jin-shan Li Tong Guo William-Yi Wang Hong-chao Kou Jun Wang State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an710072China

Cold-rolling with subsequent annealing was carried out to produce recrystallized structures with different grain sizes in an Al0.5CoCrFeNi high-entropy alloy to systematically investigate the grain growth behavior and varying *** results show that recrystallized microstructures can be achieved through an annealing process at 1200℃for 75 min to 16 h,and the average grain size in this study ranges from 5.33 to 30.03 μ*** hardness shown to be affected through grain coarsening was then measured as a function of the grain size,and it is found to follow the classical Hall-Petch strengthening.

关键词： High-entropy alloy Grain growth Recrystallization Grain boundary Hall-Petch effect

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^(18)F-FDG-PET glucose hypometabolism pattern in patients with epileptogenic hypothalamic hamartoma

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Frontiers of Medicine 2021年第6期15卷 913-921页

作者： chao Lu Kailiang Wang Fei Meng Yihe Wang Yongzhi shan Penghu Wei Guoguang Zhao Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijing100053China China International Neuroscience Institute(CHINA-INI) Beijing100053China Center of Epilepsy Beijing Institute for Brain DisorderBeijing100069China

Epileptogenic hypothalamic hamartoma is characterized by intractable gelastic seizures.A systematic analysis of the overall brain metabolic pattern in patients with hypothalamic hamartoma(HH)could facilitate the understanding of the epileptic brain network and the associated brain damage effects of *** this study,we retrospectively evaluated 27 patients with epileptogenic HH(8 female patients;age,2–33 years)by using ^(18)F-fluorodeoxyglucose-positron emission *** correlations among tomography result,seizure type,sex,and structural magnetic resonance imaging were *** metabolic patterns and voxel-based morphometry findings were assessed by group analysis with healthy *** of the whole metabolic pattern in patients with HH revealed several regional metabolic reductions in the cerebrum and an overall metabolic reduction in the *** addition,areas showing hypometabolism in the neocortex were more widely distributed ipsilaterally than contralaterally to the *** in glucose metabolism and gray matter volume in the neocortex were predominant ipsilateral to the *** conclusion,the glucose hypometabolism pattern in patients with epileptogenic HH involved the neocortex,subcortical regions,and *** characteristics of glucose hypometabolism differed across seizure type and *** in glucose metabolism and structural changes may be based on different mechanisms,but both are likely to occur ipsilateral to the HH in the *** hypothesized that the dentato-rubro-thalamic tract and cerebro-ponto-cerebellar tract,which are responsible for intercommunication between the cerebral cortex,subcortical regions,and cerebellar regions,may be involved in a pathway related to seizure propagation,particularly gelastic seizures,in patients with HH.

关键词： hypothalamic hamartoma gelastic seizure fluorodeoxyglucose-positron emission tomography voxel-based morphometry

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深度学习驱动下的目标检测研究进展综述

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计算机工程与应用 2025年第1期61卷 24-41页

作者：山显英张琳李泽慧北京建筑大学电气与信息工程学院北京102616

近年来,深度学习在GPU高性能计算能力的加持下得到了迅速推广,并在安防、医疗、工业等领域实现了广泛应用。目标检测模型的性能也在稳步提高,从传统的目标检测方法逐渐过渡到基于卷积神经网络(CNN)深度学习的进一步应用,极大地节省了人... 详细信息

近年来,深度学习在GPU高性能计算能力的加持下得到了迅速推广,并在安防、医疗、工业等领域实现了广泛应用。目标检测模型的性能也在稳步提高,从传统的目标检测方法逐渐过渡到基于卷积神经网络(CNN)深度学习的进一步应用,极大地节省了人力物力。通过参考大量文献,按照两阶段脉络梳理了目标检测的发展历程以及近年深度学习在目标检测领域内的研究进展,对比了在不同数据集上模型网络的性能,总结不同方法的优势与不足,并对领域内重要数据集作了归纳,还对目标检测算法的落地效果做了总结,特别是生活与科技中的实际应用(无人驾驶、医学图像、遥感等)。最后,还对深度学习驱动下目标检测在未来研究上的机遇和挑战作了展望。

关键词：目标检测卷积神经网络单阶段两阶段目标检测应用

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Transcriptomic analysis reveals the transcription factors involved in regulating the expression of EPSPS gene,which confers glyphosate resistance of goosegrass (Eleusine indica)

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Journal of Integrative Agriculture 2021年第8期20卷 2180-2194页

作者： ZHANG Chun YU chao-jie ZHANG Tai-jie GUO Wen-lei tiAN Xing-shan Guangdong Provincial Key Laboratory of High Technology for Plant Protection Institute of Plant ProtectionGuangdong Academy of Agricultural SciencesGuangzhou 510640P.R.China

Glyphosate inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase(EPSPS)and overexpression of the EPSPS gene is one of the molecular mechanisms conferring glyphosate resistance in weeds.A regulatory sequence of EPSPS gene was isolated previously,and an alteration in its 5´-untranslated region(UTR)pyrimidine(Py)-rich stretch element is involved in the regulation of EPSPS expression in glyphosate-resistant(GR)Eleusine ***,the transcription factors involved in this regulatory sequence remain to be *** this study,we investigated the regulatory network of EPSPS overexpression associated genes in a GR *** population by *** differentially expressed transcript analyses revealed that glyphosate treatment caused an increase in the expression of 2752 unigenes and a decrease in the expression of 4025 unigenes in the GR ***,compared to the glyphosatesusceptible(GS)*** them,1373 unigenes were identified to be co-expressed with the EPSPS gene in GR *** and KEGG pathway analyses showed that the up-regulated unigenes were mainly enriched in chloroplasts and associated with the shikimate biosynthesis pathway,chlorophy II and peroxisome metabolism ***,the expression of a Shikimate kinase which catalyzed the conversion of Shikimate to Shikimate 3-phosphate(S3P,a substrate of EPSPS),was also *** transcription factors were identified as likely to be involved in the regulation of the EPSPS expression,and three of them(ARF2,ARF8 and BPC6)showed more binding sites because of a(CT)n insertion of the 5´-UTR Py-rich stretch element in ***,the yeast one-hybrid assay illustrated that ARF8 and BPC6 could bind to the 5´-UTR Py-rich stretch element of wild type EPSPS,but could not bind to the mutated *** data suggests that the transcriptional regulation of EPSPS expression is complex and was significantly altered in GR *** discoveries provide new references for further study of the

关键词： transcriptomic EPSPS 5´-UTR Py-rich stretch element transcription factor glyphosate resistance

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Ecotoxicological effects of mixed pollutants resulted from e-wastes recycling and bioaccumulation of polybrominated diphenyl ethers in Chinese loach(Misgurnus anguillicaudatus)

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Journal of Environmental Sciences 2009年第12期21卷 1695-1701页

作者： QIN Xiaofei XIA Xijuan LI Yan ZHAO Yaxian YANG Zhongzhi FU shan ti-AN Mi ZHAO Xingru QIN Zhanfen XU Xiaobai YANG Yongjian State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-environmental Sciences Chinese Academy of Sciences Beijing 100085 China Taizhou No.1 Middle School Taizhou 318000 China

To understand potential ecotoxicological effects of electrical and electronic equipment waste （e-waste） recycling and polybrominated diphenyl ethers （PBDEs） bioaccumulation in loaches, a semi-field experiment using Chinese loach （Misgurnus anguiUicaudatus） as experimental fish was performed. Larval loaches were kept in net-cage for three months in an e-wastes recycling site and a reference site in Southeastern China. There was significant difference of the survival rate between the loaches from the e-wastes recycling site （27%, 19/70） and from reference site （70%, 49/70）. Histopathological responses were also found in all the livers examined in loaches from the e-wastes recycling site. These results showed that mixed pollutants resulted from e-wastes recycling led to ecotoxicological effects on loaches. The bioaccumulation of polybrominated diphenyl ethers （PBDEs）, the main pollutants in e-waste, in loaches was also studied, the mean concentration of total PBDEs in sediment was 6726.17 ng/g wet weight and in water samples was 4.08 ng/L （dissolved phase）. BDE 209 was the dominant congener in sediment and with relatively high concentration in water. Relatively low concentration of BDE 209 （less than 0.01% of total PBDEs） and high concentration of BDE47 （up to 39.34% of total PBDEs） were detected in loaches.

关键词： e-wastes loach ecotoxicological effects polybrominated diphenyl ethers semi-field experiment

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Multiple methods of surgical treatment combined with primary IOL implantation on traumatic lens subluxation/dislocation in patients with secondary glaucoma

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International Journal of Ophthalmology(English edition) 2014年第2期7卷 264-272页

作者： Rui Wang Chun-chao Bi Chun-Ling Lei Wen-Tao Sun shan-shan Wang Xiao-Juan Dong Department of Ophthalmology Xi'an No.4 Hospital

AIM:To describe clinical findings and complications from cases of traumatic lens subluxation/dislocation in patients with secondary glaucoma,and discuss the multiple treating methods of operation combined with primary intraocular lens(IOL)***:Non-comparativeretrospectiveobservational case ***:30 cases(30 eyes)of lens subluxation/dislocation in patients with secondary glaucoma were investigated which accepted the surgical treatment by author in the Ophthalmology of Xi’an No.4Hospital from 2007 to *** to the different situations of lens subluxation/dislocation,various surgical procedures were performed such as crystalline lens phacoemulsification,crystalline lens phacoemulsification combined anterior vitrectomy,intracapsular cataract extraction combined anterior vitrectomy,lensectomy combined anterior vitrectomy though peripheral transparent cornea incision,pars plana lensectomy combined pars plana vitrectomy,and intravitreal cavity crystalline lens phacofragmentation combined pars plana *** whether to implement trabeculectomy depended on the different situations of secondary *** posterior chamber intraocular lenses(PC-IOLs)were implanted in the capsular-bag or trassclerally sutured in the sulus decided by whether the capsular were *** outcome measures:visual acuity,intraocular pressure,the situation of intraocular lens and complications after the ***:The follow-up time was 11-36mo(21.4±7.13).Postoperative visual acuity of all eyes were improved;28 cases maintained IOP below 21 mm Hg;2cases had slightly IOL subluxation,4 cases had slightlytilted lens optical area;1 case had postoperative choroidal detachment;4 cases had postoperative corneal edema more than 1wk,but eventually recovered transparent;2 cases had mild postoperative vitreous hemorrhage,and absorbed 4wk *** was no postoperative retinal detachment,IOL dislocation,and ***:To take early treatm

关键词： crystalline lens subluxation dislocation secondary glaucoma surgical treatment

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Blue LED-pumped intense short-wave infrared luminescence based on Cr^(3+)-Yb^(3+)-co-doped phosphors

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Light(Science & Applications) 2022年第6期11卷 1194-1205页

作者： Yan Zhang Shihai Miao Yanjie Liang chao Liang Dongxun Chen Xihui shan Kangning Sun Xiao-Jun Wang Key Laboratory for Liquid-Solid Structure Evolution and Processing of Materials Ministry of EducationShandong UniversityJinan 250061China Jiangsu Bree Optronics Co. LtdNanjing 211103China Department of Physics Georgia Southern UniversityStatesboroGA 30460USA

The growing demand for spectroscopy applications in the areas of agriculture,retail and healthcare has led to extensive research on infrared light *** ability of phosphors to absorb blue light from commercial LED and convert the excitation energy into long-wavelength infrared luminescence is crucial for the design of cost-effective and high-performance phosphor-converted infrared ***,the lack of ideal blue-pumped short-wave infrared(SWIR)phosphors with an emission peak longer than 900 nm greatly limits the development of SWIR LEDs using light converter *** we have developed a series of SWIR-emitting materials with high luminescence efficiency and excellent thermal stability by co-doping Cr^(3+)-Yb^(3+) ion pairs into Lu_(0.2)Sc_(0.8)BO_(3) host *** from strong light absorption of Cr^(3+) in the blue waveband and very efficient Cr^(3+)→Yb^(3+) energy transfer,the as-synthesized Lu_(0.2)Sc_(0.8)BO_(3):Cr^(3+),Yb^(3+) phosphor emits intense SWIR light in the 900-1200 nm from Yb^(3+) under excitation with blue light at~460 *** optimized phosphor presents an internal quantum yield of 73.6%and the SWIR luminescence intensity at 100℃can still keep 88.4%of the starting value at 25℃.SWIR LED prototype device based on Lu0.2Sc0.8BO3∶Cr^(3+)Yb^(3+) phosphor exhibits exceptional luminescence performance,delivering SWIR radiant power of 18.4 mW with 9.3%of blue-to-SWIR power conversion efficiency and 5.0%of electricity-to-SWIR light energy conversion efficiency at 120 mA driving ***,under the illumination of high-power SWIR LED,covert information identification and night vision lighting have been realized,demonstrating a very bright prospect for practical applications.

关键词： luminescence intense wave

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Dynamic Analysis of A Subsea Suspended Manifold Going Through Splash Zone During Installation

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China Ocean Engineering 2022年第4期36卷 553-564页

作者： WANG Ying-ying YANG chao YANG Zhong-shan ZHAO Xiao-yu YIN Jian-xi HU Yang-dong College of Safety and Ocean Engineering China University of Petroleum-BeijingBeijing 102249China Deepwater Drilling and Production Technology Company CNOOC Energy Technology&Service LimitedZhanjiang 524057China China Vessel Scientific Research Center Wuxi 214028China

The subsea suspended manifold designed to replace the traditional foundation structure with the buoys is a new generation subsea production system that can be suspended at a certain height from the seafloor and rapidly recycled by its own *** to complex environmental conditions,its hydrodynamic performance in the splash zone is extremely important for the safety of the whole installation *** this paper,the mathematical model for the dynamic analysis of the seawater ingress process of the single-layer pre-set horizontal cabin is proposed based on the different center of gravity positions of the ***,the theoretical analysis of fiber cable is divided into infinite differential units by the discretization method,and the formulae of the horizontal displacement of the subsea suspended manifold are *** addition,the simulations are carried out to verify the rules of the dynamic responses on the subsea suspended manifold system with the consideration of the environmental conditions in the South China *** with the calculated value of the mathematical model of the cabin water ingress,the error of the simulation result by use of FLUENT is about 5.47%.Furthermore,the wave height is greater than the current impact on the lowering manifold system and the azimuth angle of the installation vessel is aligned with the direction of the environmental load.

关键词： subsea suspended manifold lowering installation seawater ingress splash zone dynamic response

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