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Open Journal of Animal Sciences 2024年第3期14卷 194-203页

作者： Van Khanh Nguyen Huong thu thi vu Au thi Hoang Yen Kim thi Pham Giang thi Thanh Nhan Hung Phu Lai Lan Doan Pham Key Laboratory of Animal Cell Biotechnology National Institute of Animal Science Hanoi Vietnam

this study aims to evaluate the effect of serum concentration, synchronization time, and confluence degree on the synchronisation efficiency of goat fibroblast cycle. The results indicated that there was no difference in the percentage of nucleated fibroblasts in the G0/G1 stage between serum concentrations of 0.3% and 0.4% (83.89% and 82.69%, respectively, P > 0.05) as well as between serum concentrations of 0.2% and 0.5% (76.95% and 75.46%, respectively, P > 0.05). The percentage of nucleated fibroblasts in the G0/G1 stage was highest at the concentration of 0.3% and lowest in the control group (83.89% vs. 62.67%, P 0.05). The beneficial effect of high confluence was confirmed by the large percentage of nucleated fibroblasts at the G0/G1 stage. The 60% confluency was significantly lower than the 80% and 100% confluency (73.44%, 86.63%, and 87.17%, respectively, P < 0.05). The results indicate that the goat fibroblast cycle synchronization is the most effective at the serum concentration of 0.3%, 72 hours of synchronization and 100% confluency.

关键词： Goat Fibroblast Cycle Synchronisation Serum Concentration Synchronization Time Confluence

Marker-Assisted Selection of Xa21 Conferring Resistance to Bacterial Leaf Blight in indica Rice Cultivar LT2

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Rice science 2018年第1期25卷 52-56页

作者： Hue thi NGUYEN Quang Hong vu Tan Van MAI thu thi NGUYEN Lam Duc vu Tung Thanh NGUYEN Long Viet NGUYEN Hien thu thi vu Hue thi NONG Trung Nguyen DINH Nakano TOSHITSUGU Liet Van vu Crop Research and Development Institute Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Agronomy Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Biotechnology Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Land Management Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Japan International Cooperation Agency 16 Phan Chu Trinh Hoan Kiem Hanoi 10000 Vietnam

Bacterial leaf blight of rice (BLB), caused by Xanthomonas oryzae pv. oryzae, is one of the most destructive diseases in Asian rice fields. A high-quality rice variety, LT2, was used as the recipient ***21, which carries the Xa21 gene, was used as the donor parent. The resistance gene Xa21 was introduced into LT2 by marker-assisted backcrossing. Three Xoo races were used to inoculate the improved lines following the clipping method. Eleven BC_3F_3 lines carrying Xa21 were obtained based on molecular markers and agronomic performance. The 11 lines were then inoculated with the three Xoo races. All the 11 improved lines showed better resistance to BLB than the recipient parent LT2. Based on the level of resistance to BLB and their agronomic performance, five lines (BC_3F_3 5.***.5.1, BC_3F_3 5.***.5.12, BC_3F_3 8.***.6.44, BC_3F_3 9.***.4.1 and BC_3F_3 9.***.4.23) were selected as the most promising for commercial release. These improved lines could contribute to rice production in terms of food security.

关键词： rice backcrossing bacterial leaf blight marker-assisted selection

Anticancer effects of saponin and saponin–phospholipid complex of Panax notoginseng grown in Vietnam

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Asian Pacific Journal of Tropical Biomedicine 2016年第9期6卷 795-800页

作者： thu Dang Kim Hai Nguyen Thanh Duong Nguyen thuy Loi vu Duc thu vu thi Hung vu Manh Patcharee Boonsiri Tung Bui Thanh Department of Pharmacology and Clinical Pharmacy School of Medicine and PharmacyVietnam National University Department of Pharmaceutics and Pharmaceutical Technology School of Medicine and PharmacyVietnam National University Department of Pharmacology Hanoi University of Pharmacy Department of Pharmacognosy and Traditional Pharmacy School of Medicine and PharmacyVietnam National University Faculty of Biology VNU University of Science Key Laboratory of Enzyme and Protein Technology VNU University of Science Department of Pharmacology School of PharmacyLac Hong University Department of Biochemistry Faculty of MedicineKhon Kaen University

Objective:To evaluate the antitumor activity both in vitro and in vivo of saponin–phospholipid complex of Panax ***:The in vitro cytotoxic effect of saponins extract and saponin–phospholipid complex against human lung cancer NCI-H460 and breast cancer cell lines BT474 was examined using MTS *** in vivo evaluation of antitumor potential,saponin and saponin–phospholipid complex were administered orally in rats induced mammary carcinogenesis by 7,12-dimethylbenz(a)anthracene,for 30 ***:Our data showed that saponin–phospholipid complex had stronger anticancer effect compared to saponin *** IC50 values of saponin–phospholipid complex and saponin extract for NCI-H460 cell lines were 28.47 mg/m L and 47.97 mg/mL,respectively and these values for BT474 cells were 53.18 mg/mL and 86.24 mg/mL,*** vivo experiments,administration of saponin,saponin–phospholipid complex and paclitaxel(positive control) effectively suppressed 7,12-dimethylbenz(a) anthracene-induced breast cancer evidenced by a decrease in tumor volume,the reduction of lipid peroxidation level and increase in the body weight,and elevated the enzymatic antioxidant activities of superoxide dismutase,catalase,glutathione peroxidase in rat breast ***:Our study suggests that saponin extract from Panax notoginseng and saponin–phospholipid complex have potential to prevent cancer,especially breast cancer.

关键词： Panax notoginseng Saponin Saponin–phospholipid complex Breast cancer Antitumor

Transient response of doubly-curved bio-inspired composite shells resting on viscoelastic foundation subject to blast load using improved first-order shear theory and isogeometric approach

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Defence Technology（防务技术） 2024年第8期38卷 171-193页

作者： thuy Tran thi thu Tu Nguyen Anh Hue Nguyen thi Hong Nguyen thi School of Mechanical and Automotive Engineering Hanoi University of IndustryHanoiViet Nam Faculty of Technical Fundamental University of Transport TechnologyHanoiViet Nam Faculty of Mechanical Engineering Thuyloi University175 Tay SonDong DaHanoiViet Nam

Investigating natural-inspired applications is a perennially appealing subject for scientists. The current increase in the speed of natural-origin structure growth may be linked to their superior mechanical properties and environmental resilience. Biological composite structures with helicoidal schemes and designs have remarkable capacities to absorb impact energy and withstand damage. However, there is a dearth of extensive study on the influence of fiber redirection and reorientation inside the matrix of a helicoid structure on its mechanical performance and reactivity. The present study aimed to explore the static and transient responses of a bio-inspired helicoid laminated composite(B-iHLC) shell under the influence of an explosive load using an isomorphic method. The structural integrity of the shell is maintained by a viscoelastic basis known as the Pasternak foundation, which encompasses two coefficients of stiffness and one coefficient of damping. The equilibrium equations governing shell dynamics are obtained by using Hamilton's principle and including the modified first-order shear theory,therefore obviating the need to employ a shear correction factor. The paper's model and approach are validated by doing numerical comparisons with respected publications. The findings of this study may be used in the construction of military and civilian infrastructure in situations when the structure is subjected to severe stresses that might potentially result in catastrophic collapse. The findings of this paper serve as the foundation for several other issues, including geometric optimization and the dynamic response of similar mechanical structures.

关键词： Blast load Modified first-order shear theory Biological composite structures

An isogeometric approach for nonlocal bending and free oscillation of magneto-electro-elastic functionally graded nanobeam with elastic constraints

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Frontiers of Structural and Civil Engineering 2024年第9期18卷 1401-1423页

作者： thu Huong NGUYEN thi Van Ke TRAN Quoc Hoa PHAM School of Mechanical and Automotive Engineering Hanoi University of IndustryHanoi 100000Vietnam Faculty of Mechanical Engineering Le Quy Don Technical UniversityHanoi 100000Vietnam Faculty of Engineering and Technology Nguyen Tat Thanh UniversityHo Chi Minh City 700000Vietnam

this work uses isogeometric analysis(IGA),which is based on nonlocal hypothesis and higher-order shear beam hypothesis,to investigate the static bending and free oscillation of a magneto-electro-elastic functionally graded(MEE-FG)nanobeam subject to elastic boundary constraints(BCs).The magneto-electric boundary condition and the Maxwell equation are used to calculate the variation of electric and magnetic potentials along the thickness direction of the *** study is innovative since it does not use the conventional boundary ***,an elastic system of straight and torsion springs with controllable stiffness is used to support nanobeams’beginning and end positions,creating customizable *** governing equations of motion of nanobeams are established by applying Hamilton’s principle and IGA is used to determine deflections and natural frequency *** studies were performed to evaluate the convergence and accuracy of the proposed *** from this,the impact of the input parameters on the static bending and free oscillation of the MEE-FG nanobeam is examined in *** findings could be valuable for analyzing and designing innovative structures constructed of functionally graded MEE materials.

关键词： elastic boundary conditions isogeometric analysis nanobeam via nonlocal theory grading of magneto-electro-elastic functions

Comparative Chemical Research in Essential Oils from Six Apiaceae Species Growing in the Northern Region of Vietnam

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1677-1687页

作者： Nguyen Quang Hung Nguyen Thanh Tung Nguyen Phuong Hanh Chu thi thu Ha Nguyen thi Nhung Nguyen Thai An vu Xuan Giang Luong Van Hao Oleh Koshovyi Ain Raal Institute of Ecology and Biological Resources Vietnam Academy of Science and Technology(VAST)Cau GiayHa Noi100000Viet Nam Graduate University of Science and Technology Vietnam Academy of Science and Technology(VAST)Cau GiayHa Noi100000Viet Nam Department of Pharmacognosy Faculty of Pharmacognosy and Traditional MedicineHanoi University of PharmacyHoan KiemHa Noi100000Viet Nam Sa Pa Research Center of Medicinal Materials National Institute of Medicinal MaterialsDien Bien PhuSa PaLao Cai330000Viet Nam Institute of Pharmacy Faculty of MedicineUniversity of TartuTartu50411Estonia

Our study aimed to compare the essential oil(EO)concentration and composition of several Apiaceae species growing in the Northern region of *** yields of EOs from materials ranged from 0.03%(root EO of Angelica acutiloba and aerial parts EO of Heracleum bivittatum)-0.27%(leaf EO of Xyloselinum vietnamense).Gas chromatography-mass spectrometry(GC-MS)allowed the identiﬁcation of 74 components in the EOs of six Apiaceae species,making up 94.4%–100.0%of the *** EO from Angelica acutiloba,(Z)-ligustilide accounted for an extremely large proportion(94.9%).EO of Angelica pubescens was dominated by six character-istic components includingα-pinene(21.5%),β-phellandrene(18.1%),p-cymene(12.2%),3-methylnonane(8.7%),o-cymene(8.1%),and D-sylvestrene(6.2%).The EO from Cryptotaenia japonica was characterized by high amounts ofα-selinene(48.7%),β-selinene(23.7%),and trans-β-farnesene(5.4%).The EOs from leaves and stems of Xyloselinum vietnamense were characterized by high concentrations of sabinene(69.8%and 33.8%),4-terpineol(8.7%and 7.4%)andβ-pinene(4.0%and 6.5%)while EOs from aerial parts and root of Xylo-selinum leonidii comprise four characteristic monoterpenes includingα-pinene(28.2%and 52.8%),β-pinene(7.9%and 10.3%),β-phellandrene(7.6%and 15.3%),and sabinene(3.0%and 4.1%).Additionally,cryptone is also one of the major components in the EO of Xyloselinum leonidii(13.2%in the aerial parts oil and 2.8%in the root oil).In the EOs isolated from the aerial parts and root of Heracleum bivittatum,α-pinene(22.5%and 70.2%)andβ-pinene(43.2%and 20.0%)were the predominant *** appeared in the EO from aerial parts of Heracleum bivittatum with a relatively high concentration(13.5%)while bornyl acetate(5.1%)was also one of the main components in the EO from its aerial parts but was not detected in other Apiaceae species in the present *** databases help identify and control the quality of plant material studied from the family Apiaceae growing in Vietnam.

关键词： Apiaceae essential oil terpenoids gaschromatography-mass spectrometry

Nonlocal isogeometric analysis for bidirectional functionally graded porous curved microbeams with arbitrary boundary conditions

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Acta Mechanica Sinica 2024年第8期40卷 194-218页

作者： thu-Huong Nguyen thi Van Ke Tran Van-Minh Phung Van Hai Trinh Quoc Hoa Pham Faculty of Mechanical Engineering Hanoi University of IndustryHanoi100000Vietnam Faculty of Mechanical Engineering Le Quy Don Technical UniversityHanoi100000Vietnam Institute of Vehicle and Energy Engineering Le Quy Don Technical UniversityHanoi100000Vietnam Faculty of Engineering and Technology Nguyen Tat Thanh UniversityHo Chi Minh City700000Vietnam

this research aims to analyze the static bending and free vibration behaviors of bidirectional functionally graded porous(BFGP)curved microbeams with elastic boundary conditions resting on a Pasternak’s elastic foundation in a hygro-thermal *** analysis based on non-uniform rational B-splines,first-order shear deformation theory,nonlocal elasticity theory combined with the modified strain gradient theories,modified Timoshenko beam theory are formulated to depict bending and shear deformations of BFGP curved ***,because using the modified Timoshenko beam theory,this study removes the requirement for a shear correction factor and describes shear stress by zero at the upper and lower cross-sectional sites of the BFGP curved *** from traditional boundary conditions,where the beginning and end positions of a curved beam are connected by an elastic system of straight and torsion *** allows for greater flexibility in controlling the stiffness of the springs to obtain arbitrary *** assess the accuracy and convergence of the proposed approach,validation numerical examples were conducted in the various examples.

关键词： Bidirectional functionally graded porous material Elastic boundary condition Isogeometric analysis Curved microbeams Nonlocal elasticity theory Modified strain gradient theory

Prevalence and risk factors associated with long COVID symptoms in children and adolescents in a southern province of Vietnam

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Asian Pacific Journal of Tropical Medicine 2024年第3期17卷 119-128,I0001,I0002页

作者： Huynh Ngoc Linh Nguyen The Tan Le thi Minh thu Nguyen Tu Loan Nguyen thi To Uyen Le Thanh Thao Trang Truong Thanh Nam Doan Hoang Phu Faculty of Medicine Ca Mau Medical CollegeCa Mau 98000Vietnam Ca Mau Obstetrics and Pediatrics Hospital Ca Mau 98000Vietnam Faculty of Basic Science and Public Health Dong Thap Medical CollegeDong Thap 81000Vietnam Graduate University of Sciences and Technology Vietnam Academy of Science and TechnologyHa Noi 10000Vietnam Community Public Health Research Program School of Public HealthWalailak UniversityNakhon Si Thammarat 80160Thailand Faculty Public Health Can Tho University of Medicine and PharmacyCan Tho City 94000Vietnam Doctoral Program in Health Sciences College of Graduate StudiesWalailak UniversityNakhon Si Thammarat 80160Thailand

Objective:To investigate the prevalence and risk factors associated with long COVID symptoms among children and adolescents who have recovered from ***:this study applied a cross-sectional approach within community settings in a southern province of Vietnam.A structured questionnaire featuring socio-demographic information and common long COVID symptoms was *** correlation coefficients assessed associations among pairs of long COVID ***,multivariable logistic regression models were performed to investigate the risk factors of long COVID in recovered COVID-19 children and ***:Among 422 participants,39.3%reported long COVID symptoms,with a prevalence of 45.2%(SD=0.5)in children and 22.2%(SD=0.4)in *** symptoms reported were cough 34.6%(SD=0.5),fatigue 20.6%(SD=0.4),shortness of breath 10.9%(SD=0.3),and lack of appetite 6.6%(SD=0.3).Concerning risk factors of long COVID,a higher risk was observed among demographic groups,including girls(OR 1.25,95%CI 1.15-1.37;Pthis study provide crucial guidance for predicting the factors associated with the occurrence of long COVID in pediatric patients,contributing to strategic interventions aimed at mitigating the long COVID risks among children and adolescents in Vietnam.

关键词： Long COVID Prevalence Risk factors Children Adolescent Vietnam

Promoting sustainable consumption and circular economy:the intention of Vietnamese youth consumers to purchase products made from recycled plastics

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Chinese Journal of Population,Resources and Environment 2024年第2期22卷 194-203页

作者： Hong thi thu Nguyen University of Science and Education The University of DanangLe Duan RoadDanang 550000Vietnam

Recycling is viewed as a key component in a circular economy and serves as an ideal solution for promoting *** the global plastic crisis,plastic recycling practices have been adopted worldwide,leading to the production of various products made from recycled plastics(PRP).Nevertheless,a gap persists between consumption and demand for such products,which is primarily attributed to a lack of comprehension from the consumer *** the pivotal role consumers play in the adoption of these products,this study explores consumers’intentions to purchase *** is particularly significant in Vietnam,which is an emerging economy aspiring to achieve the objectives of a circular economy and sustainable *** an integrated cognitive-emotional framework comprising the Valence Theory and the Norm Activation Model,data from 564 Vietnamese students were gathered and analyzed using structural equation *** results show that awareness of consequences is a major driver of consumer purchase intentions,followed by perceived ease of application and monetary *** results also indicate that health concerns have the strongest effect on purchase intention and in the negative side,meaning that the health-related risk is the primary concern for consumers during the decision-making *** research holds substantial value for academics and managers,as it aids in the theoretical exploration and the formulation of strategies to improve consumer acceptance of PRP.

关键词： Recycled plastics Purchase intention Sustainable consumption Circular economy Valence theory Norm activation model

Assessment of the Quality of Frozen-Thawed Semen or Epididymal Sperm in Three Native Vietnamese Pig Breeds

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Open Journal of Animal Sciences 2023年第3期13卷 283-297页

作者： Van Khanh Nguyen Huong thu thi vu Huong Le thi Nguyen Huong thi Nguyen Au thi Hoang Dat Van Le Nhung Tuyet thi Nguyen Hieu Trung Phan Yen Kim thi Pham Son Phan Le Quynh Anh Le Quynh Anh Le Lan Doan Pham Minh Quang Luu Muoi thi Nguyen Key Laboratory of Animal Cell Biotechnology National Institute of Animal Science Hanoi Vietnam National Institute of Animal Science Hanoi Vietnam Ministry of Science and Technology Hanoi Vietnam Animal Experiments and Domestic Animal Conservation Center National Institute of Animal Science Hanoi Vietnam

Our aim was to evaluate the quality of ejaculated and epididymal frozen-thawed pig sperm of endangered Vietnam native pig breeds. Ejaculated sperm was collected from live boars and epididymal sperm was collected from slaughtered boars of the MuongTe, Kieng Sat and Co Binhthuan breeds and frozen in 0.25 ml straws using a protocol established earlier for modern pig breeds. We evaluated the sperm quality after thawing in terms of motility and rates of viable and abnormal spermatozoa. Our results revealed that the sperm motility and rates of viable and abnormal frozen-thawed sperm were >30%, >44%, and thuan breed, ejaculated sperm generated higher cleavage, blastocyst and hatching rates than did the epididymal sperm (60.11% vs 56.02%, 17.23% vs 14.31%, 3.78% vs 2.34%, respectively, P 0.05). In the Co Binhthuan breed, the rate of pregnancy of ejaculated groups was similar to that of the epididymal group. In conclusion, the ejaculated and epididymal sperm of native Vietnamese pigs were successfully frozen. We succeeded in creating embryos in vitro and pregnant pigs after artificial insemination from frozen-thawed semen in three native Vietnamese pig breeds for the first time. The use of the ejaculated sperm improved the production of native pig embryos in vitro efficiency.

关键词： Native Vietnamese Pig In Vitro Porcine Embryo Epididymal Ejaculate Artificial Insemination