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Time Optimizing near the Pay Zone

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Engineering（科研） 2017年第10期9卷 848-859页

作者： Ali K. Darwesh thorkild maack rasmussen Nadhir Al-Ansari Department of Civil Environmental and Natural Resources Engineering Lulea University of Technology Lulea Sweden

Well control techniques are used in oil and gas drilling operations to control bottom hole pressure and avoid any fluid influx from formation to the well. These techniques are highly important near the pay zone in term of time. Controlling formation fluid pressure and thereby the formations behavior in a predictable fashion will help toward more optimized environmental friendly drilling operation. Time consumed to control the formation fluid pressure will range between few hours to many days. This paper discusses hydrostatic pressure distribution and changes near the pay zone for one oil blocks in Kurdistan, in the northern part of Iraq. Obtaining homogeneous increase in some drilling fluid properties will help the engineer to better interpret sampling of the lithological columns and reduce potential hole problems and operation time.

关键词： Fluid Pressure Well Control Drilling Fluid Formation Pay Zone

Kicks Controlling Techniques Efficiency in Term of Time

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Engineering（科研） 2017年第5期9卷 482-492页

作者： Ali K. Darwesh thorkild maack rasmussen Nadhir Al-Ansari Department of Civil Environmental and Natural Resources Engineering Lule&aring University of Technology Lule&aring Sweden

Kicks are the result of under balance drilling operation. Time consumed to control the kicks will be different in depending on the controlling technique. Drilling fluid considered as a first barrier to control formation pressure and well kicks. Any advance in drilling fluids leads to more controlled operation in term of time. This paper will follow the general increasing profile of pressure before entering the reservoir. Both methods of well controlling technique;circulating techniques and non-circulating have been implemented in many oil blocks. The process of designing and casing selection, setting depth and many other issues is predominately dependent on the utilization of accurate values of formation pressure. Formation pressures used to design safe mud weights to overcome fracturing the formation and prevent well kicks. Hence the emphasis has been placed on the practical utilization of kicks pressure near the reservoir. The presented relationships will help the engineer to better understand lithological columns and reduce potential hole problems during the kick appearance. Selecting the best well controlling practical method can lead to not harming the reservoir and more production later. Changes in some drilling fluid properties have been proposed with increasing the depth without damaging the reservoir. Suggestions in relation to the casing setting point of the intermediate section are also proposed. Standard equations with proper modification for gases and safety margin have been proposed for the future drilling operation in oil fields above the reservoir.

关键词： Driller Technique Engineer Technique Drilling Fluid Kicks Reservoir

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阿拉伯菲利克斯

Interaction of Diet/Lifestyle Intervention and TCF7L2 Genotype on Glycemic Control and Adiposity among Overweight or Obese Adults:Big Data from Seven Randomized Controlled Trials Worldwide

2021年

作者： (丹)托基尔·汉森(thorkild Hansen)

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Health Data Science 2021年第1期2021卷 174-183页

作者： Tao Huang Zhenhuang Zhuang Yoriko Heianza Dianjianyi Sun Wenjie Ma Wenxiu Wang Meng Gao Zhe Fang Emilio Ros Liana C.Del Gobbo Jordi Salas-Salvadó Miguel A.Martínez-González Jan Polak Markku Laakso Arne Astrup Dominique Langin Jorg Hager Gabby Hul Torben Hansen Oluf Pedersen Jean-Michel Oppert Wim H.M.Saris Peter Arner Montserrat Cofán Sujatha Rajaram Jaakko Tuomilehto Jaana Lindström Vanessa D.de Mello Alena Stancacova Matti Uusitupa Mathilde Svendstrup thorkild I.A.Sørensen Christopher D.Gardner Joan Sabaté Dolores Corella J.Alfredo Martinez Lu Qi Department of Epidemiology&Biostatistics School of Public HealthPeking UniversityChina Department of Global Health School of Public HealthPeking UniversityChina Key Laboratory of Molecular Cardiovascular Sciences Ministry of Education China Global Health Institute Peking University China Department of Epidemiology School of Public Health and Tropical MedicineTulane UniversityNew OrleansLAUSA Department of Nutrition Harvard T.H.Chan School of Public HealthBostonMAUSA Department of Endocrinology&Nutrition Institut d’Investigacions Biomèdiques August Pi SunyerHospital ClínicBarcelonaSpain CIBER Fisiopatologia de la Obesidad y Nutrición(CIBERobn) Instituto de Salud Carlos III(ISCIII)MadridSpain Stanford Prevention Research Center Stanford UniversityStanford CAUSA Human Nutrition Unit Faculty of Medicine and Health SciencesPere Virgili Health Research InstituteRovira i Virgili UniversityReusSpain University of Navarra Department of Preventive Medicine and Public HealthMedical School&IDISNAPamplonaSpain Department for the Study of Obesity and Diabetes Third Faculty of MedicineCharles UniversityPragueCzech Republic Department of Medicine University of Eastern FinlandKuopioFinland University of Copenhagen Department of NutritionExercise and SportsFaculty of ScienceCopenhagenDenmark Institut National de la Santéet de la Recherche Médicale(Inserm) UMR1048Institute of Metabolic and Cardiovascular DiseasesUniversity of Toulouse and Paul Sabatier UniversityToulouseFrance NestléInstitute of Health Sciences LausanneSwitzerland Department of Human Biology NUTRIM School of Nutrition and Translational Research in MetabolismMaastricht University Medical Centre+MaastrichtNetherlands Section of Metabolic Genetics Novo Nordisk Foundation Center for Basic Metabolic ResearchFaculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark Sorbonne Université Institute of Cardiometabolism and Nutrition(ICAN)Department of NutritionPitié-Salpêtrière HospitalAssistance Publique-

*** strongest locus which associated with type 2 diabetes(T2D)by the common variant rs7903146 is the transcription factor 7-like 2 gene(TCF7L2).We aimed to quantify the interaction of diet/lifestyle interventions and the genetic effect of TCF7L2 rs7903146 on glycemic traits,body weight,or waist circumference in overweight or obese adults in several randomized controlled trials(RCTs).*** October 2016 to May 2018,a large collaborative analysis was performed by pooling individualparticipant data from 7 *** RCTs reported changes in glycemic control and adiposity of the variant rs7903146 after dietary/lifestyle-related interventions in overweight or obese *** treatment interaction models which used the genetic effect encoded by the allele dose and common covariates were applicable to individual participant data in all *** the joint analysis,a total of 7 eligible RCTs were included(n=4,114).Importantly,we observed a significant effect modification of diet/lifestyle-related interventions on the TCF7L2 variant rs7903146 and changes in fasting *** with the control group,diet/lifestyle interventions were related to lower fasting glucose by-3.06(95%CI,-5.77 to-0.36)mg/dL(test for heterogeneity and overall effect:I^(2)=45:1%,p<0:05;z=2:20,p=0:028)per one copy of the TCF7L2 T risk ***,regardless of genetic risk,diet/lifestyle interventions were associated with lower waist ***,there was no significant change for diet/lifestyle interventions in other glycemic control and adiposity traits per one copy of TCF7L2 risk *** findings suggest that carrying the TCF7L2 T risk allele may have a modestly greater benefit for specific diet/lifestyle interventions to improve the control of fasting glucose in overweight or obese adults.

关键词： TCF7L2 weight finding