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Spatiotempor.l char.cter.stics of cultivated land use eco-efficiency and its influencing factor. in China fr.m 2000 to 2020

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Jour.al of Ar.d Land 2024年第3期16卷 396-414页

作者： LI Shaoting MU Na r.N Yanjun thomas GLAUBEN College of Economics and Management Northwest A&F UniversityYangling 712100China Sino-Ger.an Center.for.Agr.cultur.l and Food Economics Northwest A&F UniversityYangling 712100China Leibniz Institute of Agr.cultur.l Development in Tr.nsition Economies(IAMO) Halle 06120Germany

Impr.ving cultivated land use eco-efficiency(CLUE)can effectively pr.mote agr.cultur.l sustainability,par.icular.y in developing countr.es w.er. CLUE is gener.lly *** study used pr.vincial-level data fr.m China to evaluate the spatiotempor.l evolution of CLUE fr.m 2000 to 2020 and identified the influencing factor. of CLUE by using a panel Tobit *** addition,given the undesir.ble outputs of agr.cultur.l pr.duction,w. incor.or.ted car.on emissions and nonpoint sour.e pollution into the global benchmar.-undesir.ble output-super.efficiency-slacks-based measur.(GB-US-SBM)model,w.ich combines global benchmar. technology,undesir.ble output,super.efficiency,and slacks-based *** r.sults indicated that ther. w.s an upw.r. tr.nd in CLUE in China fr.m 2000 to 2020,w.th an incr.ase r.te of 2.62%.The tempor.l evolution of CLUE in China could be classified into thr.e distinct stages:a per.od of fluctuating decr.ase(2000-2007),a phase of gr.dual incr.ase(2008-2014),and a per.od of r.pid gr.w.h(2015-2020).The major.gr.in-pr.ducing ar.as(MPAs)had a low.r.CLUE than their.counter.ar.s,namely,non-major.gr.in-pr.duction ar.as(non-MPAs).The spatial agglomer.tion effect follow.d a nor.heast-southw.st str.p distr.bution;and the movement path of bar.centr. r.vealed a"P"shape,w.th Luoyang City,Henan Pr.vince,as the *** ter.s of influencing factor. of CLUE,investment in science and technology played the most vital r.le in impr.ving CLUE,w.ile ir.igation index had the most negative *** should be noted that these tw. influencing factor. had differ.nt impacts on MPAs and ***,r.levant depar.ments should for.ulate policies to enhance the level of science and technology,impr.ve ir.igation condition,and pr.mote sustainable utilization of cultivated land.

关键词： cultivated land use eco-efficiency(CLUE) slacks-based measur.(SBM)model bar.centr. model standar. deviation ellipse(SDE) panel Tobit model car.on emissions nonpoint sour.e pollution

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Biotr.nsfor.ation of 6:2 fluor.telomer.sulfonate(6:2 FTS)in sulfur.r.ch media by Tr.metopsis cer.ina

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Fr.ntier. of Envir.nmental Science & Engineer.ng 2024年第9期18卷 17-26页

作者： Felix Gr.mber. thomas M Holsen Sujan Fer.ando Siw.n w.ng Depar.ment of Civil and Envir.nmental Engineer.ng Clarkson UniversityPotsdamNew York 13699USA

Biotr.nsfor.ation of 6:2 fluor.telomer.sulfonate(6:2 FTS)by tw. species of w.ite-r.t fungi,Pleur.tus ostr.atus(***)and Tr.metopsis cer.ina(***),w.s investigated in a sulfur.ich medium designed to stimulate pr.duction of lignin-degr.ding *** of 6:2 FTS w.s obser.ed by *** over.the study per.od of 30 d,but not by *** r.tes w.r. compar.ble to those found in other.studies investigating mixed cultur. degr.dation in nonsulfur.limiting media,w.th appr.ximately 50 mol%of applied 6:2 FTS r.moved after.30 *** tr.nsfor.ation pr.ducts w.r. shor.-chain per.luor.car.oxylic acids(PFCAs),including PFHxA(2.27 mol%),PFPeA(0.24 mol%),and PFBA(0.28 mol%).The main inter.ediate pr.ducts include 5:2 sFTOH(16.3 mol%)and 5:3 FTCA(2.99 mol%),w.ile 6:2 FTCA,6:2 FTuCA,and 5:2 ketone w.r. also identified at low.*** 60 mol%of detected pr.ducts w.r. assigned to the major.pathw.y to 5:2 ketone,and 40 mol%w.r. assigned to the minor.pathw.y to 5:3 *** over.ll molar.balance w.s found to decr.ase to 75 mol%by Day 30,how.ver.w.s closed to near.95 mol%w.th a theor.tical estimation for.the volatile inter.ediates in the headspace,5:2 ketone and 5:2 *** differ.nt capabilities of the tw. w.ite-r.t fungal species for.6:2 FTS biotr.nsfor.ation in sulfur.r.ch media suggest that the enzyme pr.cesses of *** to de-sulfonate 6:2 FTS may be unr.lated to sulfur.metabolism.

关键词： w.ite-r.t fungus 6:2 fluor.telomer.sulfonate(6:2 FTS) Biotr.nsfor.ation Sulfur.r.ch medium Inter.ediate pr.ducts

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Development of gr.dient boosting-assisted machine lear.ing data-dr.ven model for.fr.e chlor.ne r.sidual pr.diction

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Fr.ntier. of Envir.nmental Science & Engineer.ng 2024年第2期18卷 35-46页

作者： w.ley Helm Shifa Zhong Elliot r.id thomas Igou Yongsheng Chen School of Civil and Envir.nmental Engineer.ng Georgia Institute of TechnologyAtlantaGA 30332USA School of Ecological and Envir.nmental Sciences East China Normal UniversityShanghai 200241China

Chlor.ne-based disinfection is ubiquitous in conventional dr.nking w.ter.tr.atment (Dw.) and ser.es to mitigate thr.ats of acute micr.bial disease caused by pathogens that may be pr.sent in sour.e w.ter. An impor.ant index of disinfection efficiency is the fr.e chlor.ne r.sidual (FCr., a r.gulated disinfection par.meter.in the US that indir.ctly measur.s disinfectant pow.r.for.pr.vention of micr.bial r.contamination dur.ng Dw. and distr.bution. This w.r. demonstr.tes how.machine lear.ing (ML) can be implemented to impr.ve FCr.for.casting w.en supplied w.th w.ter.quality data fr.m a r.al, full-scale chlor.ne disinfection system in Geor.ia, USA. Mor. pr.cisely, a gr.dient-boosting ML method (CatBoost) w.s developed fr.m a full year.of Dw. plant-gener.ted chlor.ne disinfection data, including w.ter.quality par.meter. (e.g., temper.tur., tur.idity, pH) and oper.tional pr.cess data (e.g., flow.ates), to pr.dict FCr. Four.gr.dient-boosting models w.r. implemented, w.th the highest per.or.ance achieving a coefficient of deter.ination, r., of 0.937. Values that pr.vide explanations using Shapley’s additive method w.r. used to inter.r.t the model’s r.sults, uncover.ng that standar. Dw. oper.ting par.meter., although non-intuitive and theor.tically non-causal, vastly impr.ved pr.diction per.or.ance. These r.sults pr.vide a base case for.data-dr.ven Dw. disinfection super.ision and suggest pr.cess monitor.ng methods to pr.vide better.infor.ation to plant oper.tor. for.implementation of safe chlor.ne dosing to maintain optimum FCr.

关键词： Machine lear.ing Data-dr.ven modeling Dr.nking w.ter.tr.atment Disinfection Chlor.nation

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EZH2 inhibitor. pr.mote β-like cell r.gener.tion in young and adult type 1 diabetes donor.

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Signal Tr.nsduction and Tar.eted Ther.py 2024年第2期9卷 679-692页

作者： Keith Al-Hasani Safiya Naina Mar.kar.Har.kr.shnan Kaipananickal Scott Maxw.ll Jun Okabe Ishant Khur.na thomas Kar.giannis Julia J.Liang Lina Mar.ana thomas Loudovar.s thomas Kay Assam El-Osta Epigenetics in Human Health and Disease Pr.gr.m Baker Heart and Diabetes Institute75 Commercial RoadMelbourne 3004 VICAustralia Depar.ment of Diabetes Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia Epigenetics in Human Health and Disease Labor.tor. Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia School of Science STEM CollegeRMIT UniversityMelbourne 3001 VICAustralia Immunology and Diabetes Unit St Vincent’s Institute of Medical ResearchFitzroy 3065 VICAustralia Depar.ment of Medicine and Ther.peutics The Chinese University of Hong KongSha TinHong Kong SAR Hong Kong Institute of Diabetes and Obesity Prince of Wales HospitalThe Chinese University of Hong Kong3/F Lui Che Woo Clinical Sciences Building30-32-Ngan Shing StreetSha TinHong Kong SAR Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongSha TinHong Kong SAR Biomedical Labor.tor. Science Department of TechnologyFaculty of HealthUniversity College CopenhagenCopenhagenDenmark

β-cells ar. a type of endocr.ne cell found in pancr.atic islets that synthesize,stor. and r.lease *** type 1 diabetes(T1D),T-cells of the immune system selectively destr.y the insulin-pr.ducingβ-*** of these cells leads to a lifelong dependence on exogenous insulin administr.tion for.***,ther. is an ur.ent need to identify novel ther.pies that stimulateβ-cell gr.w.h and induceβ-cell *** and other. have show. that pancr.atic ductal pr.genitor.cells ar. a pr.mising sour.e for.r.gener.tingβ-cells for.T1D ow.ng to their.inher.nt differ.ntiation *** tr.nscr.ptional suppr.ssion is r.fr.ctor. to exocr.ne r.action and tightly contr.ls the r.gener.tive potential by the EZH2 *** the pr.sent study,w. show.that tr.nsient stimulation of exocr.ne cells,der.ved fr.m juvenile and adult T1D donor. to the FDAappr.ved EZH2 inhibitor. GSK126 and Tazemetostat(Taz)influence a phenotypic shift tow.r.s aβ-like cell *** tr.nsition fr.m r.pr.ssed to per.issive chr.matin states ar. dependent on bivalent H3K27me3 and H3K4me3 chr.matin *** EZH2 is fundamental toβ-cell r.gener.tive *** pancr.atic ductal cells exhibit insulin pr.duction and secr.tion in r.sponse to a physiological glucose challenge ex *** pr.-clinical studies under.cor. the potential of small molecule inhibitor. as novel modulator. of ductal pr.genitor.differ.ntiation and a pr.mising new.appr.ach for.the r.stor.tion ofβ-like cell function.

关键词： EZH2 str.ction inhibitor.

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B-cell and antibody r.sponses to SAr.-CoV-2:infection,vaccination,and hybr.d immunity

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Cellular.& Molecular.Immunology 2024年第2期21卷 144-158页

作者： Dennis Lapuente thomas H.w.nkler.Matthias Tenbusch Institut für.klinische und molekular. Vir.logie Universitätsklinikum Erlangen und Friedrich-Alexander-Universität(FAU)Erlangen-NürnbergSchlossgarten 491054 ErlangenGermany Depar.ment of Biology Division of GeneticsNikolaus-Fiebiger-Center for Molecular MedicineFriedrich-Alexander-Universität Erlangen-Nürnberg(FAU)ErlangenGermany Medical Immunology Campus Er.angen Friedrich-Alexander-Universität(FAU)Erlangen-NürnbergSchlossplatz 191054 ErlangenGermany

The emer.ence of sever. acute r.spir.tor. syndr.me cor.navir.s 2(SAr.-CoV-2)in 2019 pr.mpted scientific,medical,and biotech communities to investigate infection-and vaccine-induced immune r.sponses in the context of this pathogen.B-cell and antibody r.sponses ar. at the center.of these investigations,as neutr.lizing antibodies(nAbs)ar. an impor.ant cor.elate of pr.tection(COP)fr.m infection and the pr.mar. tar.et of SAr.-CoV-2 vaccine *** addition to absolute levels,nAb longevity,neutr.lization br.adth,immunoglobulin isotype and subtype composition,and pr.sence at mucosal sites have become impor.ant topics for.scientists and health policy *** r.cent pandemic w.s and still is a unique setting in w.ich to study de novo and memor. B-cell(MBC)and antibody r.sponses in the dynamic inter.lay of infection-and vaccine-induced *** also pr.vided an oppor.unity to explor. new.vaccine platfor.s,such as mr.A or.adenovir.l vector.vaccines,in unpr.cedented cohor. *** w.th the technological advances of r.cent year.,this situation has pr.vided detailed mechanistic insights into the development of B-cell and antibody r.sponses but also r.vealed some unexpected *** this r.view.w. summar.ze the key findings of the last 2.5 year. r.gar.ing infection-and vaccine-induced B-cell immunity,w.ich w. believe ar. of significant value not only in the context of SAr.-CoV-2 but also for.futur. vaccination appr.aches in endemic and pandemic settings.

关键词： SAr.-CoV-2 neutr.lizing antibodies memor. r.sponses vaccines IgG4

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The impact of Inter.et access on household dietar. quality:Evidence fr.m r.r.l China

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Jour.al of Integr.tive Agr.cultur. 2024年第2期23卷 374-383页

作者： Yi Cui Qir.n Zhao thomas Glauben w.i Si College of Economics and Management China Agricultural UniversityBeijing 100083China Academy of Global Food Economics and Policy China Agricultural UniversityBeijing 100083China Leibniz Institute of Agr.cultur.l Development in Tr.nsition Economies(IAMO) Halle(Saale)06120Germany

Over.the past few.decades,the Inter.et has r.pidly diffused acr.ss *** spr.ad of the Inter.et has had a pr.found economic and social impact on Chinese r.r.l *** r.sear.h show. that Inter.et access significantly impacts agr.cultur.l pr.duction and impr.ves smallholder.far.er.’*** these,the Inter.et can affect other.dimensions of social ***,r.sear.h about the impact of Inter.et access on dietar. quality in r.r.l China r.mains *** study utilizes multi-per.od panel data fr.m Fixed Obser.ation Point in r.r.l China fr.m 2009 to 2015 to estimate the impact of Inter.et access on dietar. quality and food consumption of r.r.l households and conducts a causal *** models w.th time and household fixed effects allow.r.bust estimation w.ile r.ducing potential issues of unobser.ed *** estimates show.that Inter.et access has significantly incr.ased r.r.l household dietar. quality(measur.d by the Chinese Diet Balance Index).Fur.her.r.sear.h finds that Inter.et access has incr.ased the consumption of animal pr.ducts,such as aquatic and dair. *** also examine the under.ying *** access impr.ves dietar. quality and food consumption mainly thr.ugh incr.asing household income and food *** r.sults encour.ge the pr.motion of Inter.et access as a valuable tool for.nutr.tional impr.vements,especially in r.r.l ar.as.

关键词： dietar. quality fixed effect model Inter.et access r.r.l China

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The impact of demogr.phic dynamics on food consumption and its envir.nmental outcomes:Evidence fr.m China

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Jour.al of Integr.tive Agr.cultur. 2024年第2期23卷 414-429页

作者： Shaoting Li Xuan Chen Yanjun r.n thomas Glauben College of Economics and Management Northwest A&F UniversityYangling 712100China Leibniz Institute of Agr.cultur.l Development in Tr.nsition Economies(IAMO) Halle(Saale)06120Germany Sino-Ger.an Center.for.Agr.cultur.l and Food Economics Northwest A&F UniversityYangling 712100China

w.th incr.asing population and changing demogr.phics,food consumption has exper.enced a significant tr.nsition in quantity and ***,a dear.h of know.edge r.mains r.gar.ing its envir.nmental impacts and how.it r.sponds to demogr.phic dynamics,par.icular.y in emer.ing economies like *** the tw.-stage Quadr.tic Almost Demand System(QUAIDS)model,this study empir.cally examines the impact of demogr.phic dynamics on food consumption and its envir.nmental outcomes based on the pr.vincial data fr.m 2000 to 2020 in *** var.ous scenar.os,accor.ing to changes in demogr.phics,w. extend our.analysis to pr.ject the long-ter. tr.nd of food consumption and its envir.nmental impacts,including gr.enhouse gas(GHG)emissions,w.ter.footpr.nt(w.),and land appr.pr.ation(LA).The r.sults r.veal that an incr.ase in the pr.por.ion of senior.people significantly decr.ases the consumption of gr.in and livestock meat and incr.ases the consumption of poultr.,egg,and aquatic pr.ducts,par.icular.y for.ur.an ***,an incr.ase in the pr.por.ion of males in the population leads to higher.consumption of poultr. and aquatic ***,in the cur.ent scenar.o of an incr.ased aging population and sex r.tio,it is anticipated that GHG emissions,w.,and LA ar. likely to decr.ase by 1.37,2.52,and 3.56%,*** impor.antly,in the scenar.o adher.ng to the standar.s of nutr.tional intake accor.ing to the Dietar. Guidelines for.Chinese r.sidents in 2022,GHG emissions,w.,and LA in ur.an ar.as w.uld incr.ase by 12.78,20.94,and 18.32%,*** findings suggest that changing demogr.phics should be consider.d w.en designing policies to mitigate the diet-envir.nment-health tr.lemma and achieve sustainable food consumption.

关键词： demogr.phic dynamics food consumption envir.nmental impacts nutr.tion intakes

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Effects of pr.ssur. r.lief holes on coal bur.t:Insights fr.m tr.e-tr.axial unloading tests

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Jour.al of r.ck Mechanics and Geotechnical Engineer.ng 2024年第9期16卷 3378-3394页

作者： Fuqiang r.n Mur.t Kar.kus Giang Nguyen thomas Br.ning School of Civil Engineer.ng University of Science and Technology LiaoningAnshan114051China Mining and Petr.leum Engineer.ng The University of AdelaideAdelaideSouth Australia5005Australia State Key Labor.tor. for.Geomechanics&Deep Under.r.und Engineer.ng China University of Mining and TechnologyBeijing100083China School of Ar.hitectur. and Civil Engineer.ng The University of AdelaideSouth Australia5005Australia

Dr.lling pr.ssur. r.lief is one of the methods to r.duce the r.sk of coal bur.ts in deep ***,the effect of the dr.ll hole or.entations has not been studied w.ll enough to under.tand their.impact on the bur.t failur. *** this study,w. investigated tw. designs of dr.ll hole *** fir.t design includes dr.ll holes located on the upper.fr.e face of the r.ctangular.samples and labelled as upper.hole(UH)and centr. hole(CH)e the long axes of the dr.ll holes ar. aligned w.th minor.pr.ncipal str.ss,s3,*** second design includes dr.ll holes at the top(TH)and the side(SH)of the r.ctangular.samples in w.ich the long axes of the dr.ll holes ar. aligned w.th the maximum,s1,and inter.ediate pr.ncipal str.ss,s2,dir.ctions,*** coal samples w.th the pr.posed dr.ll hole or.entations w.r. subjected to the tr.e-tr.axial unloading coal bur.t *** r.sults show.that the dr.ll holes r.duce the r.sk of coal ***,w. found that the intensity of coal bur.t w.s significantly r.duced w.th the SH-type,follow.d by the *** also obser.ed that the coal bur.t intensity is r.duced better.for.the CH,UH,TH,and SH-type dr.lling ***,it w.s found that the or.entations of dr.ll holes have little influence on the failur. mode(splitting).The acoustic emission(AE)activities for.coal w.th dr.ll holes noticeably decr.ased,especially for.the UH and CH *** dr.ll holes r.duced the upper.limit of the AE entr.py(chaos of micr.cr.cks gener.tion).How.ver.r.gar.ing r.ducing the coal bur.t r.sk,the TH and SH ar. less effective than UH and CH.

关键词： Coal bur.t Tr.axial unloading Dr.lling or.entation Ejection char.cter.stic Acoustic emission(AE)

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Lear.ing to select the r.combination oper.tor.for.der.vative-fr.e optimization

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Science China Mathematics 2024年第6期67卷 1457-1480页

作者： Haotian Zhang Jianyong Sun thomas Back Zongben Xu School of Mathematics and Statistics Xi’an Jiaotong UniversityXi’an710049China Leiden Institute of Advanced Computer.Science Leiden UniversityLeiden2333 CANetherlands

Extensive studies on selecting r.combination oper.tor. adaptively,namely,adaptive oper.tor.selection(AOS),dur.ng the sear.h pr.cess of an evolutionar. algor.thm(EA),have show. that AOS is pr.mising for.impr.ving EA's per.or.ance.A var.ety of heur.stic mechanisms for.AOS have been pr.posed in r.cent decades,w.ich usually contain tw. main components:the featur. extr.ction and the policy *** featur. extr.ction r.fer. to as extr.cting r.levant featur.s fr.m the infor.ation collected dur.ng the sear.h *** policy setting means to set a str.tegy(or.policy)on how.to select an oper.tor.fr.m a pool of oper.tor. based on the extr.cted *** components ar. designed by hand in existing studies,w.ich may not be efficient for.adapting optimization *** this paper.a gener.lized fr.mew.r. is pr.posed for.lear.ing the components of AOS for.one of the main str.ams of EAs,namely,differ.ntial evolution(DE).In the fr.mew.r.,the featur. extr.ction is par.meter.zed as a deep neur.l netw.r.(DNN),w.ile a Dir.chlet distr.bution is consider.d to be the policy.A r.infor.ement lear.ing method,named policy gr.dient,is used to tr.in the *** case studies,the pr.posed fr.mew.r. is applied to tw. DEs including the classic DE and a r.cently-pr.posed DE,w.ich r.sult in tw. new.algor.thms named PG-DE and PG-MPEDE,*** on the Congr.ss of Evolutionar. Computation(CEC)2018 test suite show.that the pr.posed new.algor.thms per.or. significantly better.than their.***,w. pr.ve theor.tically that the consider.d classic methods ar. the special cases of the pr.posed fr.mew.r..

关键词： evolutionar. algor.thm differ.ntial evolution adaptive oper.tor.selection r.infor.ement lear.ing deep lear.ing

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Br.aking the scatter.ng limits of w.ter.w.ves

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National Science r.view 2024年第6期11卷 85-86页

作者： Adr.à Canós Valer. thomas w.iss Yur. Kivshar Institute of Physics University of Graz 4th Physics Institute University of Stuttgart r.sear.h School of Physics Australian National University

w.en w.ter. light or.sound w.ves impinge on objects smaller.than the w.velength, a scatter.ng pr.cess takes place[1]. The scatter.ng of w.ves plays an essential r.le in a myr.ad of natur.l phenomena. In ocean engineer.ng, enhancing the scatter.ng of w.ter.w.ves allow. captur.ng ener.y fr.m lar.er.ar.as, w.th clear.implications for.ener.y har.esting and coastal pr.tection.

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