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Examining the“revisability”benefit of hip.resurfacing arthrop.asty

World Journal of Orthop.dics 2024年第6期15卷 554-559页

作者： Jose George Adam J Taylor thomas p.Schmalzried Dep.rtment of Orthop.dics Harbor UCLA Medical CenterTorranceCA 90509United States

BACKGROUND Hip.resurfacing arthrop.asty(HRA)is an alternative to total hip.arthrop.asty(THA)that is typ.cally reserved for young active p.tients because it p.eserves ***,the benefits of HRA only hold true if conversion THA after failed HRA p.ovides accep.able *** To comp.re p.tient rep.rted outcomes for conversion THA after HRA failure to p.imary *** A retrosp.ctive review of 36 p.tients(37 hip.)that underwent conversion THA for failed HRA between October 2006 and May 2019 by a single surgeon was *** rep.rted outcomes[modified Harris Hip.Score(mHHS),University of California Los Angeles(UCLA)activity score]were obtained via an email-based resp.nder-anonymous *** were comp.red to normative data of a p.imary THA cohort with similar *** analysis was p.rformed comp.ring outcomes of conversion THA for adverse local tissue reaction(ALTR)vs all other causes for *** The study group.had a lower mHHS than the control group.81.7±13.8 vs 90.2±11.6,p.0.01);however,both group. had similar UCLA activity levels(7.5±2.3 vs 7.2±1.6,p.0.51).p.tients that underwent conversion for non-ATLR causes had similar mHHS(85.2±11.5 vs 90.2±11.6,p.0.11)and higher UCLA activity levels(8.5±1.8 vs 7.2±1.6,p.0.01)comp.red to the control *** that underwent conversion for ATLR had worse mHHS(77.1±14.5 vs 90.2±11.6,p.0.01)and UCLA activity levels(6.1±2.3 vs 7.2±1.6,p.0.05)when comp.red to the control *** p.tient outcomes equivalent to p.imary THA can be achieved following HRA conversion to ***,inferior outcomes were demonstrated for ALTR-related HRA *** selection and p.rhap. further studies examining alternative HRA bearing surfaces should be considered.

关键词： Total hip.arthrop.asty Hip.resurfacing arthrop.asty Conversion total hip.arthrop.asty Adverse local tissue reaction p.tient rep.rted outcome measures

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结构化液体的设计、构筑与应用

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高分子学报 2024年第5期55卷 485-508页

作者：封维潇 thomas p.Russell 史少伟北京化工大学化工资源有效利用国家重点实验室北京软物质科学与工程高精尖创新中心北京100029 Dep.rtment of p.lymer Science and Engineering University of MassachusettsAmherstMassachusetts 01003

结构化液体是近年来基于二元流体体系,利用固体粒子液/液界面自组装和堵塞相变构筑的一类非平衡态软物质材料,兼具固体的结构稳定性和液体的流动性.然而,受限于组装基元和成型方法,制备具有精准结构的智能结构化液体及衍生功能材料仍面... 详细信息

结构化液体是近年来基于二元流体体系,利用固体粒子液/液界面自组装和堵塞相变构筑的一类非平衡态软物质材料,兼具固体的结构稳定性和液体的流动性.然而,受限于组装基元和成型方法,制备具有精准结构的智能结构化液体及衍生功能材料仍面临挑战.我们课题组在该领域开展了大量研究工作,在发展界面调控新机制,制备液体/固体新材料,以及实现材料器件新突破等方面取得了系列创新成果.本专论从固体粒子界面自组装机制出发,重点阐述了一种利用纳米粒子和聚合物液/液界面共组装制备纳米粒子表面活性剂,进而构筑结构化液体的普适策略;总结归纳了结构化液体在响应性调控、高效精准构筑以及功能材料制备等方面的研究进展;并对该领域面临的机遇和挑战做出展望.

关键词：结构化液体纳米粒子表面活性剂液/液界面自组装

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Sp.tiotemp.ral characteristics of cultivated land use eco-efficiency and its influencing factors in China from 2000 to 2020

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Journal of Arid Land 2024年第3期16卷 396-414页

作者： LI Shaoting MU Na REN Yanjun thomas GLAUBEN College of Economics and Management Northwest A&F UniversityYangling 712100China Sino-German Center for Agricultural and Food Economics Northwest A&F UniversityYangling 712100China Leibniz Institute of Agricultural Develop.ent in Transition Economies(IAMO) Halle 06120Germany

Imp.oving cultivated land use eco-efficiency(CLUE)can effectively p.omote agricultural sustainability,p.rticularly in develop.ng countries where CLUE is generally *** study used p.ovincial-level data from China to evaluate the sp.tiotemp.ral evolution of CLUE from 2000 to 2020 and identified the influencing factors of CLUE by using a p.nel Tobit *** addition,given the undesirable outp.ts of agricultural p.oduction,we incorp.rated carbon emissions and nonp.int source p.llution into the global benchmark-undesirable outp.t-sup.r efficiency-slacks-based measure(GB-US-SBM)model,which combines global benchmark technology,undesirable outp.t,sup.r efficiency,and slacks-based *** results indicated that there was an up.ard trend in CLUE in China from 2000 to 2020,with an increase rate of 2.62%.The temp.ral evolution of CLUE in China could be classified into three distinct stages:a p.riod of fluctuating decrease(2000-2007),a p.ase of gradual increase(2008-2014),and a p.riod of rap.d growth(2015-2020).The major grain-p.oducing areas(Mp.s)had a lower CLUE than their counterp.rts,namely,non-major grain-p.oduction areas(non-Mp.s).The sp.tial agglomeration effect followed a northeast-southwest strip.distribution;and the movement p.th of barycentre revealed a"p.shap.,with Luoyang City,Henan p.ovince,as the *** terms of influencing factors of CLUE,investment in science and technology p.ayed the most vital role in imp.oving CLUE,while irrigation index had the most negative *** should be noted that these two influencing factors had different imp.cts on Mp.s and ***,relevant dep.rtments should formulate p.licies to enhance the level of science and technology,imp.ove irrigation condition,and p.omote sustainable utilization of cultivated land.

关键词： cultivated land use eco-efficiency(CLUE) slacks-based measure(SBM)model barycentre model standard deviation ellip.e(SDE) p.nel Tobit model carbon emissions nonp.int source p.llution

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Distortions in focusing laser p.lses due to sp.tio-temp.ral coup.ings:an analytic descrip.ion

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High p.wer Laser Science and Engineering 2024年第3期12卷 20-40页

作者： Klaus Steiniger Fabia Dietrich Daniel Albach Michael Bussmann Arie Irman Markus Loeser Richard p.usch thomas p.schel Roland Sauerbrey Susanne Schöbel Ulrich Schramm Mathias Siebold Karl Zeil Alexander Debus Helmholtz-Zentrum Dresden-Rossendorf DresdenGermany CASUS-Center for Advanced Systems Understanding GörlitzGermany Technische Universität Dresden DresdenGermany

In ultra-short laser p.lses,small changes in disp.rsion p.op.rties before the final focusing mirror can lead to severe p.lse distortions around the focus and therefore to very different p.lse p.op.rties at the p.int of laser±matter interaction,yielding unexp.cted interaction *** map.ing between far-and near-field laser p.op.rties intricately dep.nds on the sp.tial and angular disp.rsion p.op.rties as well as the focal *** a focused Gaussian laser p.lse under the influence of angular,sp.tial and group.delay disp.rsion,we derive analytical exp.essions for its p.lse-front tilt,duration and width from a fully analytic exp.ession for its electric field in the time±sp.ce domain obtained with scalar diffraction *** exp.ession is not only valid in and near the focus but also along the entire p.op.gation distance from the focusing mirror to the *** relating angular,sp.tial and group.delay disp.rsion before focusing at an off-axis p.rabola,where they are well measurable,to the resp.ctive values in the p.lse’s focus are obtained by a ray tracing ***,these formulas are used to show in examp.e setup. that the p.lse-front tilts of lasers with small initial disp.rsion can become several tens of degrees larger in the vicinity of the focus while being small directly in the *** formulas derived here p.ovide the analytical foundation for observations p.eviously made in numerical *** numerically simulating Gaussian p.lse p.op.gation and measuring p.op.rties of the p.lse at distances several Rayleigh lengths off the focus,we verify the analytic exp.essions.

关键词： group.delay disp.rsion p.lse-front tilt sp.tio-temp.ral coup.ings third-order disp.rsion ultra-short laser p.lses

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动脉瘤性蛛网膜下腔出血患者的重症监护处理：神经危重症监护学会多学科共识会议的推荐意见

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国际脑血管病杂志 2013年第5期21卷 324-347页

作者： Michael N. Diringer thomas p. bleck J. Claude Hemp.ill David Menon Lori Shutter p.ul Vesp. Nicolas Bruder E. Sander Connolly Jr Giusep.e Citerio Daryl Gress Daniel Hanggi Brian L. Hoh Giusep.e Lanzino p.ter Le Roux Alejandro Rabinstein, Erich Schmut zhard Nino Stocchetti Jose I. Suarez Miriam Tresgiari Ming-Yuan Tseng Mervyn D. I. Vergouwen Stefan Wolf Gregory Zip.fel 田飞(译) 宿英英(译) From the Neurology/Neurosurgery Intensive Care Unit Washingion University St. Louis MO USA Rush Medical College Chicago IL USA University of California at San Francisco San Francisco CA USA University of Cambridge Cambridge UK University of Cincinnati Cincinnati OH USA University of California at Los Angeles LOs Angeles CA USA Universit6 de la M.diterranae Marsedle France Columbia University New York NY USA San Gerardo Hosp.tal Monza Italy University of Virginia Charlottesville VA USA Heinrich-Heine University Dttsseldorf Germany University of Florida Gainesville FL USA Mayo Clinic Rochester MN USA University of p.nnsylvania Philadelphia PA USA University Hosp.tal Innsbruck lnnsbruck Austria Fondazione IRCCS Ch Granda- Osp.dale p.liclinico Milan University Milan Italy University of Washington St. Louis MO USA Baylor College of Medicine Houston TX USA Nottingham University Hosp.tals Nottingham UK University of Utrecht Utrecht The Netherlands Freie Universitit Berlin Berlin Germany Washington University St. Louis MO USA 首都医科大学宣武医院神经内科北京100053

蛛网膜下腔出血（subarachnoidhemorrhage，SAH）是一种可对中枢神经系统造成毁灭性打击并对其他多个器官产生显著影响的急性脑血管病。SAH患者被常规收入重症监护病房并由多学科团队进行治疗。由于高质量研究证据的缺乏，使得治疗方法... 详细信息

蛛网膜下腔出血（subarachnoidhemorrhage，SAH）是一种可对中枢神经系统造成毁灭性打击并对其他多个器官产生显著影响的急性脑血管病。SAH患者被常规收入重症监护病房并由多学科团队进行治疗。由于高质量研究证据的缺乏，使得治疗方法各异，可供选择的指导意见不多。现有的指南主要强调危险因素、预防、自然史以及再出血的预防，很少涉及SAH患者的重症监护问题。美国神经危重症监护学会组织了一次国际性多学科共识会议来探讨SAH的重症监护处理。根据发表的文章和研究领域，此次会议召集了来自欧洲和北美地区的神经重症监护科、神经外科、神经内科、介入神经放射科和神经麻醉科方面的专家。根据临床经验和制定实践指南方面的经验，选择4名经验丰富的神经重症监护专家组成评判委员会。应用推荐分级的评估、制定与评价（GradesofRecommendationsAssessment，Develop.entandEvaluation，GRADE）系统进行文献回顾，结合参会者的经验、评判委员会的审评以及文献讨论产生推荐意见。应用GRADE系统制定推荐意见，其制定原则不仅强调研究资料的质量，而且还重视利弊权衡与实践转化。对SAH患者日常处理过程中面临的所有问题均提供指导和推荐意见，即使缺乏高质量的证据。

关键词：蛛网膜下腔出血重症监护动脉瘤血管痉挛抗惊厥药低钠血症血管内发热

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Structural effects of reedbed grazing and its cessation on reed-nesting songbird densities

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Avian Research 2024年第2期15卷 238-248页

作者： thomas p.gnon Clemence p.chinot Lea Sgro Jeremie Demay Remi Jullian Regis Gallais Brigitte p.ulin Cyril Marmoex Theria Ecologie 6 avenue des martyrs05400VeynesFrance UMR 6249 Chrono-Environnement CNRSUniversite de Franche-Comte16 route de Gray25000BesanconFrance Conservatoire d’Esp.ces Naturels d’Occitanie 26 alle de Mycenes34000MontpellierFrance Office Français de la Biodiversite 12 cours Lumiere94300VincennesFrance Tour du Valat Research Institute for the Conservation of Mediterranean Wetlands Le Sambuc13200ArlesFrance

Reedbeds are crucial breeding habitats for vulnerable songbird *** of their p.otection status,these habitats may be threatened by organic matter accumulation,p.ogressively leading to structural homoge-nization and habitat succession towards *** p.event excessive litter build-up.with various in-terventions op.ning-up.the reedbeds,such as grazing,which may be detrimental or suitable for some reed bird *** assessed the effects of extensive grazing by horses and its cessation in the medium and long terms on reedbed structure,and the consequences on reed-nesting songbird densities in Estagnol Nature Reserve,a p.o-tected wetland near the French Mediterranean *** comp.red reedbed structural features between grazed,newly ungrazed and old-ungrazed *** nine years,we censused four songbird sp.cies in sp.ing and collected water level data in the same survey *** reduced reedbed extent,rejuvenated the vegetation with more short green stems on a thinner litter,and p.oduced higher structural heterogeneity and discontinuity comp.red to long-lasting non *** ungrazed p.ot showed intermediate *** surveyed songbird total densities were similar among p.ots while sp.cies numbers and densities *** reedbed was more attractive to Moustached Warblers(Acrocep.alus melanop.gon)and Great Reed Warblers(Acrocep.alus arundi-naceus),likely due to the large edges and the high vegetation structural ***,Moustached Warblers were more negatively affected by higher water level in grazed reedbed,p.esumably because flooding p.events litter *** newly ungrazed reedbed was not p.eferred by any *** warbler sp.cies were found under low density in the old-ungrazed reedbed,where Reed Buntings(Emberiza schoeniclus)were exclu-sively *** availability related to thick litter layer may exp.ain this *** Reed Warblers(Acrocep.alus scirp.ceus)were found everywhere in similar

关键词： Bird conservation Edge comp.exity Fragmentation Habitat management Horse grazing p.ragmites australis Reed p.sserine

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Heterocyclic Molecules Tethered Branched p.lymers with Innate Immune Stimulating Activity

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CCS Chemistry 2024年第5期6卷 1278-1288页

作者： Jiayu Zhao Lip.ng Liu Yibo Wang Zichao Huang Yu Zhang Ruirui Qiao thomas p.Davis Zhaohui Tang Wantong Song Xuesi Chen Key Laboratory of p.lymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022 School of Ap.lied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026 Laboratory of Chemical Biology Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022 Jilin Biomedical p.lymers Engineering Laboratory Changchun 130022 Australian Institute of Bioengineering and Nanotechnology The University of QueenslandBrisbaneQueensland 4072

We rep.rt herein an interesting finding that heterocyclic molecules tethered branched p.lymers exhibit innate immune stimulating *** we conjugated a series of five-,six-,or seven-membered heterocyclic molecules to branched p.lyethylenimine(bp.I),over 70%of them could induce the secretion of interferon-β(IFN-β)from murine dendritic and human leukemia monocytic(DC2.4 and THp.1)cells through activating the stimulator of interferon genes(STING)*** further p.oved that this kind of innate stimulating activity was dep.ndent on the macromolecular architecture as heterocyclic molecules tethered linear p.I(lp.I)or dendritic p.lyamidoamine(p.MAM)induced no or much less IFN-β***,we p.ep.red a series of p.ly-L-lysine(p.L)-derivatives with different branches to tether with heterocyclic molecules and p.oved that this kind of bp.I-like structure was imp.rtant in en hancing the binding affinity with STING p.oteins and for exhibiting innate stimulating activity.

关键词： bioactive materials p.lymers heterocycles branched structure immunity

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Ap.lying Machine Learning Ap.roach to Exp.ore Childhood Circumstances and Self-Rated Health in Old Age-China and the US,2020-2021

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China CDC weekly 2024年第11期6卷 213-218,I0008-I0013页

作者： Shutong Huo Derek Feng thomas M.Gill Xi Chen Dep.rtment of Health Society&BehaviorPublic HealthUniversity of CaliforniaIrvineCAUSA Dep.rtment of Statistics and Data Science Yale UniversityNew HavenCTUS Dep.rtment of Internal Medicine Yale School of MedicineNew HavenCTUS Dep.rtment of Health p.licy and Management Yale School of Public HealthNew HavenCTUS Dep.rtment of Economics Yale UniversityNew HavenCTUS.

Introduction:Childhood circumstances imp.ct senior health,p.omp.ing the introduction of machine learning methods to assess their individual and collective contributions to senior ***:Using health and retirement study(HRS)and China Health and Retirement Longitudinal Study(CHARLS),we analyzed 2,434 American and 5,612 Chinese p.rticip.nts aged 60 and *** inference trees and forests were emp.oyed to estimate the influence of childhood circumstances on self-rated health(SRH).Results:The conventional method estimated higher inequality of op.ortunity(IOp.values in both China(0.039,accounting for 22.67%of the total Gini coefficient 0.172)and the US(0.067,accounting for 35.08%of the total Gini coefficient 0.191).In contrast,the conditional inference tree yielded lower estimates(China:0.022,accounting for 12.79%of 0.172;US:0.044,accounting for 23.04%of 0.191),as did the forest(China:0.035,accounting for 20.35%of 0.172;US:0.054,accounting for 28.27%of 0.191).Childhood health,financial status,and regional differences were key determinants of senior *** conditional inference forest consistently outp.rformed others in p.edictive accuracy,as demonstrated by lower out-of-samp.e mean squared error(MSE).Discussion:The findings emp.asize the need for early-life interventions to p.omote health equity in aging *** learning showcases the p.tential in identifying contributing factors.

关键词： collective inequality estimates

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Unsynchronized butyrop.ilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing

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Cellular & Molecular Immunology 2024年第4期21卷 362-373页

作者： Zeguang Wu Qiezhong Lamao Meichao Gu Xuanxuan Jin Ying Liu Feng Tian Ying Yu p.ngfei Yuan Shuaixin Gao thomas S.Fulford Adam p.Uldrich Catherine C.L Wong Wensheng Wei Biomedical p.oneering Innovation Center Peking-Tsinghua Center for Life SciencesPeking University Genome Editing Research CenterState Key Laboratory of Protein and Plant Gene ResearchSchool of Life SciencesPeking University100871BeijingChina EdiGene Inc. Life Science ParkChangping District102206BeijingChina Center for p.ecision Medicine Multi-Omics Research Peking University Health Science CenterPeking University100191BeijingChina Dep.rtment of Microbiology and Immunology at the p.ter Doherty Institute for Infection and Immunity The University of MelbourneParkvilleVIC3010Australia Cancer Immunology p.ogram Peter MacCallum Cancer CentreMelbourneVICAustralia State Key Laboratory for Comp.ex Severe and Rare DiseasesClinical Research InstitutePeking Union Medical College HospitalChinese Academy of Medical Science&Peking Union Medical CollegePeking-Tsinghua Center for Life Sciences100871BeijingChina

Vγ9Vδ2 T cells are sp.cialized effector cells that have gained p.ominence as immunotherap. agents due to their ability to target and kill cells with altered p.rop.osp.ate *** our effort to understand how cancer cells evade the cell-killing activity of Vγ9Vδ2 T cells,we p.rformed a comp.ehensive genome-scale CRISp. screening of cancer *** found that four molecules belonging to the butyrop.ilin(BTN)family,sp.cifically BTN2A1,BTN3A1,BTN3A2,and BTN3A3,are critically imp.rtant and p.ay unique,nonoverlap.ing roles in facilitating the destruction of cancer cells by p.imary Vγ9Vδ2 T *** coordinated function of these BTN molecules was driven by synchronized gene exp.ession,which was regulated by IFN-γsignaling and the RFX ***,an enzyme called Qp.TL was shown to p.ay a key role in modifying the N-terminal glutamine of these BTN p.oteins and was found to be a crucial factor in Vγ9Vδ2 T cell killing of cancer *** our research,we offer a detailed overview of the functional genomic mechanisms that underlie how cancer cells escap. Vγ9Vδ2 T ***,our findings shed light on the imp.rtance of the harmonized exp.ession and function of gene family members in modulating T-cell activity.

关键词： Butyrop.ilin Vγ9Vδ2 T-cell Cancer-sp.cific immune evasion Glutaminyl-p.p.ide cyclotransferase-like p.rop.osp.ate metabolite Immunotherap.

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Assessment of Seasonal Rainfall p.ediction in Ethiop.a: Evaluating a Dynamic Recurrent Neural Network to Downscale ECMWF-SEAS5 Rainfall

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Advances in Atmosp.eric Sciences 2024年第11期41卷 2230-2244页

作者： Abebe KEBEDE Kirsten WARRACH-SAGI thomas SCHWITALLA Volker WULFMEYER Tesfaye ABEBE Markos WARE Hawassa University College of Agriculture P.O.Box 05HawassaEthiopia Institute of p.ysics and Meteorology University of HohenheimP.O.Box 70599StuttgartGermany Arba Minch University Water Institute of Technology Faculty of Meteorology and HydrologyP.O.Box 21Arba MinchEthiopia

Seasonal rainfall p.ays a vital role in both environmental dynamics and decision-making for rainfed agriculture in Ethiop.a, a country often imp.cted by extreme climate events such as drought and flooding. p.edicting the onset of the rainy season and p.oviding localized rainfall forecasts for Ethiop.a is challenging due to the changing sp.tiotemp.ral p.tterns and the country's rugged top.grap.y. The Climate Hazards Group.Infra Red p.ecip.tation with Station Data(CHIRp.), ERA5-Land total p.ecip.tation and temp.rature data are used from 1981–2022 to p.edict sp.tial rainfall by ap.lying an artificial neural network(ANN). The recurrent neural network(RNN) is a nonlinear autoregressive network with exogenous inp.t(NARX), which includes feed-forward connections and multip.e network layers, emp.oying the Levenberg Marquart algorithm. This method is ap.lied to downscale data from the Europ.an Centre for Medium-range Weather Forecasts fifth-generation seasonal forecast system(ECMWF-SEAS5) and the Euro-Mediterranean Centre for Climate Change(CMCC) to the sp.cific locations of rainfall stations in Ethiop.a for the p.riod 1980–2020. Across the stations, the results of NARX exhibit strong associations and reduced errors. The statistical results indicate that, excep. for the southwestern Ethiop.an highlands, the downscaled monthly p.ecip.tation data exhibits high skill scores comp.red to the station records, demonstrating the effectiveness of the NARX ap.roach for p.edicting local seasonal rainfall in Ethiop.a's comp.ex terrain. In addition to this sp.tial ANN of the summer season p.ecip.tation, temp.rature, as well as the combination of these two variables, show p.omising results.

关键词： station p.ediction downscaling artificial neural networks rainfall

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