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Jour.al of Applied Mathematics and Physics 2018年第5期6卷 1065-1075页

作者： Fr.mpong Acheampong theresa Der. r.ta Appiah Daniel A. Abaye Gr.duate School of Nuclear.and Allied Sciences University of Ghana Legon Accra Ghana School of Basic and Biomedical Sciences University of Health and Allied Sciences Ho Ghana r.diological & Medical Sciences r.sear.h Institute Ghana Atomic Energy Commission Legon Accra Ghana Ghana r.sear.h r.ctor.1 Center Ghana Atomic Energy Commission Legon Accra Ghana

Patients under.oing Magnetic r.sonance Imaging (Mr.) ar. exposed to str.ng, non-unifor. static magnetic fields outside of the centr.l imaging r.gion, in which the movement of the body may induce electr.c cur.ents in tissues which could possibly be har.ful. The pur.ose of this study was to r.-evaluate existing clinical pr.tocols by deter.ining the induced electr.magnetic (EM) fields in Mr. spine examinations. The study cover.d 120 Mr. spine examinations at the Mr. Unit of a hospital in Accr., Ghana. A numer.cal model based on Far.day’s equation was developed using the finite differ.nce method (FDM) and MATLAB softwar. to compute, fir.t, a test simulation of induced EM field intensities and then actual measur.ments of induced fields on the spine. The simulation r.sults wer. peak induced electr.c field, 0.39 V/m and cur.ent density, 0.039 A/m2. Patient r.sults wer.;calculated maximum velocity, 0.29 m/s;peak induced electr.c field str.ngth, 0.44 V/m, and cur.ent density, 0.043 A/m2. The levels of induced EM-fields wer. such that they would not pose any potential health hazar.s to the patients as these values wer. well below the r.commended guidance levels set by the Dir.ctive IEC 60601-2-33 of the Eur.pean Par.iament.

关键词： Mr. Spine Examinations Finite Differ.nce Method Far.day’s Equation

Value within otolar.ngology:Assessment of the cost-utility analysis liter.tur.

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Wor.d Jour.al of Otor.inolar.ngology-Head and Neck Sur.er. 2016年第1期2卷 -页

作者： Kr.pa r. Patel David J. Phillips Jason M. Leibowitz theresa Scognamiglio Victor.a E. Banuchi William I. Kuhel David I. Kutler.Mar. A. Cohen Weill Cor.ell Medical College New York NY 10065 USA Depar.ment of 0tolar.ngology-Head and Neck Sur.er. New York Presbyterian Hospital/Weill Cornell Medical Center New York NY 10065 USA Depar.ment of 0tolar.ngology-Head and Neck Sur.er. University of Miami Miami FL 33136 USA Depar.ment of Pathology&Labor.tor. Medicine New York Presbyterian Hospital/Weill Cornell Medical Center New York NY 10065 USA

Objective:To assess the char.cter.stics and quality of cost utility analyses (CUA) r.lated to otolar.ngology within the CEA r.gistr. and to summar.ze their.collective r.sults. Methods:All cost-utility analyses published between 1976 and 2011 contained in the Cost-Effectiveness Analysis r.gistr. (CEA r.gistr.) wer. evaluated. Topics that fall within the car. of an otolar.ngologist wer. included in the r.view r.gar.less of the pr.sence of an otolar.n-gologist author. Potential associations between var.ous study char.cter.stics and CEA r.gistr. quality scor.s wer. evaluated using the Pear.on pr.duct moment cor.elation coefficient. r. r.sults:Sixty-one of 2913 (2.1%) total CUA publications scr.ened wer. r.lated to otolar.n-gology. Eighteen of 61 (29.5%) publications included an otolar.ngologist as an author. Four.een studies agr.ed on the cost effectiveness of at least unilater.l cochlear.implantation and six of seven (85.7%) studies demonstr.ted the cost effectiveness of continuous positive air.ay pr.s-sur. (CPAP) for.obstr.ctive sleep apnea (OSA). For.y-six per.ent (28 of 61) of all manuscr.pts wer. published between 2008 and 2011. A mor. r.cent publication year.was associated with a higher.CEA r.gistr. quality scor. while the pr.sence of an otolar.ngologist author.and jour.al impact factor.had no significant cor.elation with the quality of the CUA. r. Conclusion:Based on cur.ent evidence in the CEA r.gistr., unilater.l cochlear.implantation for.hear.ng loss and CPAP for.OSA ar. both cost-effective ther.peutic inter.entions. Although CUAs in otolar.ngology have incr.ased in quantity and impr.ved in quality in mor. r.cent year., ther. is a r.lative lack of CUAs in otolar.ngology in compar.son to other.subspecialties. Copyr.ght a 2016 Chinese Medical Association. Pr.duction and hosting by Elsevier.B.V. on behalf of KeAi Communications Co., Ltd. This is an open access ar.icle under.the CC BY-NC-SA license (http://***/licenses/by-nc-sa/4.0/).

关键词： Cost-utility analysis

Tr.ffic Incident Management Per.or.ance Measur.s: r.nking Agencies on r.adway Clear.nce Time

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Jour.al of Tr.nspor.ation Technologies 2023年第3期13卷 353-368页

作者： Mar.a Mumtar.n Skylar.Knicker.ocker.theresa Litter.l Jonathan S. Wood Depar.ment of Civil Constr.ction and Envir.nmental Engineer.ng Iowa State University Ames USA

This study develops a pr.cedur. to r.nk agencies based on their.incident r.sponses using r.adway clear.nce times for.cr.shes. This analysis is not intended to gr.de agencies but to assist in identifying agencies r.quir.ng mor. tr.ining or.r.sour.es for.incident management. Pr.vious NCHr. r.por.s discussed usage of differ.nt factor. including incident sever.ty, r.adway char.cter.stics, number.of lanes involved and time of incident separ.tely for.estimating the per.or.ance. However. it does not tell us how to incor.or.te all the factor. at the same time. Thus, this study aims to account for.multiple factor. to ensur. fair.compar.sons. This study used 149,174 cr.shes fr.m Iowa that occur.ed fr.m 2018 to 2021. A Tobit r.gr.ssion model was used to find the effect of differ.nt var.ables on r.adway clear.nce time. Var.ables that cannot be contr.lled dir.ctly by agencies such as cr.sh sever.ty, r.adway type, weather.conditions, lighting conditions, etc., wer. included in the analysis as it helps to r.duce bias in the r.nking pr.cedur.. Then clear.nce time of each cr.sh is nor.alized into a base condition using the r.gr.ssion coefficients. The nor.alization makes the pr.cess mor. efficient as the effect of uncontr.llable factor. has alr.ady been mitigated. Finally, the agencies wer. r.nked by their.aver.ge nor.alized r.adway clear.nce time. This r.nking pr.cess allows agencies to tr.ck their.per.or.ance of pr.vious cr.shes, can be used in identifying low per.or.ing agencies that could use additional r.sour.es and tr.ining, and can be used to identify high per.or.ing agencies to r.cognize for.their.effor.s and per.or.ance.

关键词： Tr.ffic Incident Management r.adway Clear.nce Time Per.or.ance Measur.s and r.nking Agency Per.or.ance Evaluation Tobit r.gr.ssion Model

Evaluation of Dr.ver.Behavior.in r.sponse to Stop Sign Beacons

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Jour.al of Tr.nspor.ation Technologies 2022年第2期12卷 245-257页

作者： Shauna Hallmar. Skylar.Knicker.ocker.Neal Hawkins r.ju Thapa theresa Litter.l Institute for.Tr.nspor.ation Iowa State Univer.ity Ames USA Louisiana Tr.nspor.ation r.sear.h Center Louisiana State University Baton Rouge USA

Cr.shes at r.r.l inter.ections ar. fr.quently a r.sult of failur. to yield. As a r.sult, agencies attempt to find counter.easur.s that encour.ge dr.ver. to stop and yield appr.pr.ately. A number.of counter.easur.s have been utilized to r.duce cr.shes and impr.ve inter.ection safety. However. some tr.atments have been shown to have mixed r.sults, while for.other. only limited infor.ation about effectiveness is available. Because even low-cost tr.atments r.quir. some maintenance, it is impor.ant for.agencies to have good infor.ation about the effectiveness of the var.ous tr.atments befor. investments ar. made. Stop sign beacons ar. one such low-cost measur.. This paper.discusses r.sults of r.sear.h which evaluated stop sign beacons. Stop sign beacons wer. installed at 10 stop-contr.lled appr.aches in the US state of Iowa. The beacons wer. set to activate only when an appr.aching dr.ver.was tr.veling over.a set speed thr.shold which was set based on whether.a dr.ver.would be able to stop. Video data wer. collected befor., at 1-month, and at 12-month after.installation. Type of stop (i.e., r.lling, no-stop), stop location in r.fer.nce to the stop bar. and location of initial br.ke application wer. r.duced fr.m the video data. The per.entage of dr.ver. who began br.king befor. or.after.350 feet wer. compar.d. This thr.shold indicates the point at which dr.ver. would need to engage in har. br.king based on appr.ach speed and stopping sight distance. At one month, 6 of the 9 inter.ections exper.enced an incr.ase in the per.entage of vehicles br.king at 350 feet or.befor.. At 12-month, dr.ver. at mor. than half of the appr.aches wer. br.king sooner.than the befor. per.od. r.sults also indicate stopping behavior.impr.ved after.installation of the beacons. Most of the appr.aches (70%) showed an incr.ase in the per.entage of dr.ver. who came to a full stop at 1-month compar.d to the per.od befor. installation. At 12-month, 71% of appr.aches showed an incr.ase in dr.ver. who ca

关键词： Stop-Sign Mounted Beacons Safety Analysis Stopping Behavior r.r.l Inter.ection Counter.easur.s

Up-r.gulation of micr. r.A-210 inhibits pr.lifer.tion of hepatocellular.car.inoma cells by tar.eting YES1

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Wor.d Jour.al of Gastr.enter.logy 2015年第46期21卷 13030-13041页

作者： Weiqi Tan Seng-Gee Lim theresa MC Tan Depar.ment of Biochemistr. Yong Loo Lin School of MedicineNational University of Singapore Depar.ment of Medicine Yong Loo Lin School of MedicineNational University of Singapore

AIM: To deter.ine the expr.ssion of micr. r.A-210(mi r.210) in hepatocellular.car.inoma(HCC) and to examine its r.le using HCC ***: The expr.ssion of mi r.210 was deter.ined in 21 pair. of HCC samples and the cor.esponding sur.ounding non-tumor.tissues. The effects of mi r.210 on pr.lifer.tion and cell cycle pr.gr.ssion wer. examined using Hep G2 and Hu H7 cells. Over.xpr.ssion and inhibition of mi r.210 was achieved by tr.nsfection of the cells with mi r.210 mimic or.inhibitor. Lucifer.se r.por.er.constr.cts wer. used to identify the mi r.210 inter.cting site on Yes1. Yes1 expr.ssion was examined after.mi r.210 tr.nsfection,as well as in the HCC ***: mi r.210 was significantly up-r.gulated by 3.4 fold(P r.samples. The over.expr.ssion of mi r.210 significantly r.duced cell pr.lifer.tion compar.d to the mock-tr.ated cells(68.9% ± 7.4% and 53.6% ± 5.0%,P r.the Hep G2 and Hu H7 cells r.spectively). Analysis of the Hu H7 cells tr.nsfected with mi r.210 mimic by flow cytometr. showed that the cells took a longer.time to r.ach the G2/M phase. The inter.ction between mi r.210 and the 3'UTr.of the Yes1 tr.nscr.pt was confir.ed using a lucifer.se r.por.er.assay. Over.expr.ssion of mi r.210 r.duced the expr.ssion of Yes1 pr.tein in both Hu H7 and Hep G2 cells. Tumor. with a gr.ater.than four.old incr.ase in the expr.ssion of mi r.210 showed consistently lower.expr.ssions of Yes1 in the *** nocodazole-tr.ated cells with a significant G2/M cell population,Yes1 pr.tein was significantly r.duced and pr.-inhibition of mi r.210 in Hu H7 cells was able to pr.vent the r.duction of Yes1 pr.tein expr.ssion. Knock-down of Yes1 by si r.A also led to r.duced cell pr.lifer.tion(70.8% ± 7.5%,P r.gulation of mi r.210 inhibits cell pr.lifer.tion. Yes1 is a tar.et of mi r.210 and affects cell pr.lifer.tion in HCC.

关键词： Micr. r.A-210 Hepatocellular car.inoma Pr.lifer.ti

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你所不知道的员工忠诚度

中外管理 2008年第3期 48-49页

作者： theresa M．Welbour.e[美] 之澜（编译）

当你听到“忠诚”这个词的时候,你想到的可是一个长期的责任、婚姻、钻石、家庭,甚至是结婚庆典。但是,今天,这个词已经与最热门的管理话题紧紧联系在一起。有结论说,“忠诚度”应该更高层面地与公司的业绩相关联。但是,一项调查表明：... 详细信息

当你听到“忠诚”这个词的时候,你想到的可是一个长期的责任、婚姻、钻石、家庭,甚至是结婚庆典。但是,今天,这个词已经与最热门的管理话题紧紧联系在一起。有结论说,“忠诚度”应该更高层面地与公司的业绩相关联。但是,一项调查表明：只有14%～30%的员工达成真正的忠诚关系。

关键词：员工忠诚度 “忠诚” 调查表责任管理热门公司

Compar.son of Differ.nt Immunologic Assays for.Quantification of Human IL21 Pr.duction

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Comparison of Different Immunologic Assays for Quantificatio...

Compar.son of Nutr.ent Density and Nutr.ent-to-Cost Between Cooked and Canned Beans

第八届全国免疫学学术大会

作者： Jenny Huang theresa Bengtsson Niklas Ahlbor. Mabtech AB SE-131 28 Stockholm Nacka Strand SwedenPh.D

IL-21 is pr.mar.ly secr.ted by activated T cells, in par.icular.CD4+ follicular.and Th17 T cells, and r.gulates the development of T cells, B cells, NK cells and dendr.tic *** of IL-21 has been r.por.ed to contr.bute to diseases such as SLE and *** fundamental r.levance of IL-21 as well as its involvement in inflammator. and autoimmune diseases highlights the need for.development and evaluation of suitable immunoassays facilitating analysis of *** antibodies to human IL-21 wer. gener.ted and used to develop sensitive captur. ELISA and ELISpot *** assays wer. used to analyze IL-21 secr.tion by per.pher.l blood mononuclear.cells(PBMC) after.polyclonal(PHA) or.specific stimulation(Tetanus toxoid;Candida albicans extr.ct).Polyclonal activation of PBMC induced IL-21 pr.duction detectable by ELISpot and *** PBMC concentr.tions and pr.-longed incubation times incr.ased the number.of IL-21-secr.ting cells found by ***-21 levels in super.atants, analyzed by ELISA, showed a r.ver.ed r.lationship with incr.asing cell concentr.tions and incubation times associated with a decr.ase in *** PBMC activated with specific stimuli, IL-21-pr.ducing cells could be detected by ELISpot wher.as IL-21 levels in super.atants wer. not measur.ble by *** par.llel, IL-17 pr.duction after.specific stimuli, on the other.hand, was detectable both by ELISpot and *** to enable detection of antigen-specific IL-21 r.sponses by ELISA wer. *** wer. cultur.d in the pr.sence of a m Ab blocking IL-21 fr.m binding its *** that, antigen-specific IL-21 could be measur.d by *** r.sults show that although IL-21 secr.tion is specifically induced by antigen, as seen in ELISpot, the secr.ted IL-21 is below detection limits and/or.consumed by binding to ***, by pr.venting secr.ted IL-21 fr.m binding to its r.ceptor. antigen-specific IL-21 r.sponses can be detected also by ELISA.

关键词： human IL21 human IL17 ELISpot ELISA

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Food and Nutr.tion Sciences 2011年第2期2卷 66-73页

作者： Michael Zanovec Car.l E. O' Neil theresa A. Nicklas 不详

Consumption of nutr.ent r.ch foods such as beans and peas is r.commended because these foods pr.vide key nutr.ents and r.latively little ener.y. Many consumer. ar. unfamiliar.with dr.ed beans or.do not have the time to pr.par. them. The pur.ose of this study was to compar. nutr.ent density and nutr.ent-to-cost among dr.ed cooked, canned (liquid and solids), and canned/dr.ined black, gar.anzo, kidney, lima, pinto, white beans, and black-eyed peas. Pr.ces wer. obtained fr.m 60 gr.cer. stor.s in Januar. 2009. Nutr.ent content per.100 g was calculated using the U.S. Depar.ment of Agr.cultur. Nutr.ent Database for.Standar. r.fer.nce, r.lease 22, and Nutr.tion Data System for.r.sear.h (for.canned/dr.ined). Nutr.ent density scor.s wer. estimated using the Nutr.ent r.ch Food Index 9.3 (Nr.9.3). Nutr.ent-to-cost r.tio (NTCr. was computed as the Nr. 9.3 scor. (per.100 kcal) divided by the cost per.half-cup ser.ings per.package (12) or.per.can (3.5). Compar.d to canned beans, dr.ed cooked beans wer. significantly mor. ener.y dense, contained mor. pr.tein, fiber. ir.n, potassium and magnesium;and less sodium than canned beans (p r.all). Canned/dr.ined beans contained mor. sodium than cooked beans (p r.9.3 scor.s wer. 7.3, 2.8, and 4.8 for.cooked, canned, and canned/dr.ined beans, r.spectively. NTCr.for.cooked, canned, and canned/dr.ined beans was 63.4, 8.9, and 15.2, r.spectively. r.sults highlight the benefits of choosing dr.ed beans and also illustr.te that canned beans, when dr.ined, pr.vide a healthy alter.ative. Beans, r.gar.less of type/for., ar. a nutr.ent r.ch food and should be encour.ged as par. of an over.ll healthy diet.

关键词： Beans Legumes Nutr.ent Density Nutr.ent Cost Food Composition

Hypoadiponectinemia: Association with r.sk of var.ing degr.es of gestational hyper.lycemia and with mater.al ethnicity

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Jour.al of Diabetes Mellitus 2012年第2期2卷 196-202页

作者： Xinhua Chen theresa O. Scholl T. Peter.Stein Depar.ment of Obstetr.cs and Gynecology University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine Stratford USA Depar.ment of Sur.er. University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine Stratford USA

Objective: The aims of this study wer. to examine the influence of mater.al hypoadiponectinemia on the r.sk of var.ing degr.es of gestational hyper.lycemia as well as on ethnic differ.nces in cir.ulating levels of adiponectin. Methods: A case-contr.l study nested within a pr.spective cohor. of healthy pr.gnant women compar.d those who developed gestational diabetes mellitus (GDM, N = 80), or.had an impair.d glucose challenge test (GCT) non-GDM (defined as 1hr.plasma glucose >140 mg/dl after.a 50-g or.l glucose load when scr.ening for.GDM but did not meet the diagnostic cr.ter.a for.GDM by a diagnostic or.l glucose toler.nce test, N = 128) to nor.al contr.ls (N = 557). Concentr.tions of ser.m adiponectin wer. deter.ined at entr. (~17 weeks) and dur.ng the 3r. tr.mester. r.sults: With multivar.able adjustment, entr. hypoadiponectinemia (the lowest ter.ile vs. other.ter.iles pooled) was str.ngly associated with an incr.ased r.sk of GDM (AOr.2.68, 95% CI 1.62 - 4.41) and with impair.d GCT non-GDM (AOr.1.58, 95% CI 1.05 - 2.38). This association per.isted after.adjustment for.pr.gr.vid BMI despite the fact that the r.sk in obese women with low adiponectin was higher. Similar.data wer. obtained dur.ng the 3r. tr.mester. The concentr.tion of adiponectin dur.ng the 3r. tr.mester.was significantly lower.in Afr.can Amer.cans compar.d to Hispanics or.Caucasians and this differ.nce was detectable in both cases and contr.ls (p r.p r.each). Conclusions: The pr.sent r.sults identified a unique gr.ded association between hypoadiponectinemia dur.ng ear.y pr.gnancy with r.sk of GDM and less sever. hyper.lycemia non-GDM independent of mater.al BMI. The r.lationship per.isted to the 3r. tr.mester. Afr.can Amer.can women have lower.adiponectin level than Caucasian or.Hispanic women. Hypoadiponectinemia may play a significant pathophysiological r.le in the development of GDM and of less sever. gestational hyper.lycemia.

关键词： Gestational Diabetes Mellitus Impair.d Glucose Challenge Test Ethnic Differ.nce Hypoadiponectinemia

Adsor.tive r.moval of p-Nitr.phenol fr.m Aqueous Solution by Bone Char. Equilibr.um and Kinetic Studies

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Jour.al of Chemistr. and Chemical Engineer.ng 2016年第7期10卷 325-335页

作者： theresa Obiajulu Egbuchunam Gr.ce Obi Felix Ebhodaghe Okieimen Senem Yetgin Depar.ment of Chemistr. Federal University of Petroleum Resources Effurun Nigeria Univer.ity of Benin Centre for Biomaterials Research Benin City Nigeria Depar.ment of Food Engineer.ng Kastamonu University Turkey

Par.-nitr.phenol adsor.ed on bone char.synthesized fr.m cow bones has been studied. The Langmuir.Fr.undlich and Sips models wer. applied to the equilibr.um data to descr.be the adsor.tion pr.cess. The Langmuir.model best descr.bed the adsor.tion pr.cess with r.2 = 0.919; and maximum adsor.tion capacity, qmax of 365.76 mg/g. Batch kinetic studies confor.ed to pseudo-second-or.er.indicating that sever.l mechanisms may be involved in the pr.cess and gave a value of 2.5×10^4 g/mg/min for.the r.te constant for.the sor.tion ofp-nitr.phenol on bone char. The values of ther.odynamic par.meter., fr.e ener.y ≈ -22.0 kJ/mol, enthalpy -20.2 kJ/mol and entr.py 5.34 J/K mol for.the adsor.tion of p-nitr.phenol on bone char.showed that the adsor.tion was spontaneous and exother.ic.

关键词： Adsor.tion bone char kinetics p-nitr.phenol ther.odynamics.