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Effectiveness of an Indoor.Air.Pollution (IAP) Inter.ention on r.ducing IAP and Impr.ving Women’s Health Status in r.r.l Ar.as of Gansu Pr.vince, China

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Open Jour.al of Air.Pollution 2015年第1期4卷 26-37页

作者： Yibin Cheng Jiaqi Kang Fan Liu Br.an A. Bassig Br.an Leader.r.Gongli He theodore r. holford Ning Tang Jian Wang Jian He Yanchang Liu Yingchun Liu Jiang Liu Xun Chen Heng Gu Xiao Ma Tongzhang Zheng Yinlong Jin Institute for.Envir.nmental Health and r.lated Pr.duct Safety Chinese Center for Disease Control and Prevention Beijing China Yale School of Public Health New Haven USA Chinese Center.for.Disease Contr.l and Pr.vention Beijing China Gansu Pr.vincial Center.for.Disease Contr.l and Pr.vention Lanzhou China West China School of Public Health Sichuan University Chengdu China

Given the deleter.ous health effects associated with indoor.air.pollution (IAP), this study was conducted to evaluate an IAP inter.ention in r.r.l ar.as in Gansu, one of the poor.st pr.vinces of China. We selected 371 r.r.l households to take par. in inter.ention measur.s including stove impr.vement and health education. Eight of 371 households wer. selected to conduct IAP sampling. Four.hundr.d and thir.een women in these households completed a questionnair. and 49 women took par. in lung function tests. After.the inter.ention, PM4 levels r.duced fr.m 455 μg/m3 to 200 μg/m3 and CO r.duced fr.m 3.40 ppm to 2.90 ppm in indoor.air. The per.entage of pr.dicted value of FEV1 and FVC impr.ved to some degr.e after.the inter.ention, but all the par.meter. of lung function assessment did not show a significant change. Pr.valence r.tes of sever.l symptoms associated with IAP significantly declined in the study population, compar.d with baseline levels. Inter.ention measur.s combining stove impr.vement with health education wer. effective in r.ducing IAP levels. Women’s health status, including eye and r.spir.tor. symptoms, also showed impr.vement. However. the effect on lung function was not appar.nt and war.anted additional follow-up. Similar.y, evaluation of the long ter. effects of the IAP inter.ention will r.quir. futur. studies.

关键词： Indoor Air Pollution Biomass Lung Function r.spir.tor. System

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Pr.natal Exposur. to Polycyclic Ar.matic Hydr.car.ons and Bir.h Weight in China

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Open Jour.al of Air.Pollution 2014年第4期3卷 100-110页

作者： Qiong Chen Tongzhang Zheng Br.an A. Bassig Yibin Cheng Br.an Leader.r.Shaobin Lin theodore holford Jie Qiu Yawei Zhang Kunchong Shi Yong Zhu Jianjun Niu Yonghong Li Huan Guo Xiaobin Hu Yinlong Jin Yale School of Public Health New Haven CT USA Office for.Cancer.r.sear.h and Contr.l Cancer Hospital of Henan Province Affiliated Cancer Hospital of Zhengzhou University Zhengzhou China Institute for.Envir.nmental Health and r.lated Pr.duct Safety Chinese Center for Disease Control and Prevention Beijing China Gansu Pr.vincial Mater.ity and Child Car. Hospital Lanzhou China Depar.ment of Healthcar. Beijing Obstetrics and Gynecology Hospital Capital Medical University Beijing China Institute for.Envir.nmental Health and r.lated Pr.duct Safety Chinese Center for Disease Control and Prevention Beijing China Xiamen City Center.for.Disease Contr.l and Pr.vention Xiamen China Depar.ment of Occupational and Envir.nmental Health and Ministr. of Education Key Lab for Environment and Health School of Public Health Tongji Medical College Huazhong University of Science and Technology Wuhan China Depar.ment of Epidemiology and Biostatistics School of Public Health Lanzhou University Lanzhou China

Adver.e bir.h outcomes ar. a leading cause of mor.ality in childr.n in China, but the envir.nmental influences of these conditions r.main lar.ely unexplained in this population. We aimed to evaluate the levels of polycyclic ar.matic hydr.car.ons (PAHs) in Chinese pr.gnant women and their.newbor.s, and to examine the association between levels of PAHs and infant bir.h weight. We conducted a cr.ss-sectional study including 81 pair. of mother. and newbor.s fr.m four.hospitals in four.differ.nt cities in China. High Per.or.ance Liquid Chr.matogr.phy was used to measur. the concentr.tion of nine PAHs in mater.al and cor. blood and multiple linear.r.gr.ssion analyses wer. used to evaluate the associations of these PAHs with infant bir.h weight. Anthr.cene (ANT) had the highest aver.ge concentr.tion and detection r.te (geometr.c mean = 69.54 ng/g and 76.5%, r.spectively) in mater.al ser.m samples, while fluor.nthene (FLT) had the highest concentr.tion and detection r.te (geometr.c mean = 68.4 ng/g and 50.6%, r.spectively) in the cor. blood. Most of the measur.d PAHs in mater.al ser.m and thr.e PAHs in cor. blood wer. inver.ely but non-significantly associated with bir.h weight. The str.ngest associations wer. obser.ed for.higher.concentr.tions of benzo (a) pyr.ne (BaP) in mater.al ser.m (230.7 g decr.ase for.levels > median vs. r.ANT in cor. blood (153.1 g decr.ase for.levels r. the pr.dominant PAHs in the mater.al and cor. blood ser.m. Ser.m concentr.tions of sever.l measur.d PAHs wer. associated with a decr.ased bir.h weight, although not significantly, suggesting that fur.her.studies with lar.er.sample sizes ar. needed to validate our.findings.

关键词： Mater.al Exposur. Polycyclic Ar.matic Hydr.car.on Bir.h Weight Fetal Development Mater.al Ser.m

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