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Prevalence and risk factors associated with long COVID symptoms in children and adolescents in a southern province of Vietnam

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Asian Pacific Journal of Tropical Medicine 2024年第3期17卷 119-128,I0001,I0002页

作者： huynh Ngoc Linh Nguyen The Tan Le Thi Minh Thu Nguyen Tu Loan Nguyen Thi To Uyen Le thanh Thao Trang Truong thanh Nam Doan Hoang Phu Faculty of Medicine Ca Mau Medical CollegeCa Mau 98000Vietnam Ca Mau Obstetrics and Pediatrics Hospital Ca Mau 98000Vietnam Faculty of Basic Science and Public Health Dong Thap Medical CollegeDong Thap 81000Vietnam Graduate University of Sciences and Technology Vietnam Academy of Science and TechnologyHa Noi 10000Vietnam Community Public Health Research Program School of Public HealthWalailak UniversityNakhon Si Thammarat 80160Thailand Faculty Public Health Can Tho University of Medicine and PharmacyCan Tho City 94000Vietnam Doctoral Program in Health Sciences College of Graduate StudiesWalailak UniversityNakhon Si Thammarat 80160Thailand

Objective:To investigate the prevalence and risk factors associated with long COVID symptoms among children and adolescents who have recovered from ***:This study applied a cross-sectional approach within community settings in a southern province of Vietnam.A structured questionnaire featuring socio-demographic information and common long COVID symptoms was *** correlation coefficients assessed associations among pairs of long COVID ***,multivariable logistic regression models were performed to investigate the risk factors of long COVID in recovered COVID-19 children and ***:Among 422 participants,39.3%reported long COVID symptoms,with a prevalence of 45.2%(SD=0.5)in children and 22.2%(SD=0.4)in *** symptoms reported were cough 34.6%(SD=0.5),fatigue 20.6%(SD=0.4),shortness of breath 10.9%(SD=0.3),and lack of appetite 6.6%(SD=0.3).Concerning risk factors of long COVID,a higher risk was observed among demographic groups,including girls(OR 1.25,95%CI 1.15-1.37;P<0.001,reference:boys),children compared to adolescents(OR 1.24,95%CI 1.12-1.37;P<0.001),overweight individuals(OR 1.14,95%CI 1.02-1.27;P=0.018,reference:healthy weight),and participants without any COVID-19 vaccination(OR 1.36,95%CI 1.20-1.54;P<0.001),or have received only one single dose(OR 1.35,95%CI 1.10-1.64;P=0.004)compared to those who have received two ***,patients with a COVID-19 treatment duration exceeding two weeks also had a higher risk of long COVID(OR 1.32,95%CI 1.09-1.60;P=0.003)than those who recovered less than seven ***:The insights from this study provide crucial guidance for predicting the factors associated with the occurrence of long COVID in pediatric patients,contributing to strategic interventions aimed at mitigating the long COVID risks among children and adolescents in Vietnam.

关键词： Long COVID Prevalence Risk factors Children Adolescent Vietnam

Effect of Freeze-Thaw and Urea in Solubility of GPC3-Csub Protein Expressed in Escherichia coli

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Journal of Biosciences and Medicines 2024年第4期12卷 288-297页

作者： Xuan-Truc Chu-Dao Kim-Tuyen huynh-Dam Dang-Thuc Ngo-Luong Quang-Luan Le thanh-Thao Vo-Nguyen Department of Medical Biotechnology Biotechnology Center of Ho Chi Minh City Ho Chi Minh City Vietnam

Glypican-3 is a protein encoded by the Glypican-3 gene located on human X chromosome (Xq26), composed of two subunits, a 40 kDa N-terminal subunit, and a 30 kDa C-terminal subunit. Glypican-3 is a currently potential target molecule for liver cancer treatments because of its over-expression and growth effects on hepatocellular carcinoma (HCC). This study examined the expression and purification of a C-terminal subunit of Glypican-3 protein (GPC3-Csub) due to its application in both diagnosis and therapy for hepatocellular carcinoma. The gene encoding for GPC3-Csub was successfully cloned into plasmid pET28a fused with an affinity tag composed of six consecutive histidine residues (His-tag). Recombinant protein GPC3-Csub was expressed in Escherichia coli BL21 (DE3) in the condition of adding 3% ethanol with IPTG induction. GPC3-Csub was extracted using repeated freeze-thaw cycles with lysozyme, and inclusion bodies were solubilized by 8M Urea, SDS 10% in pH 12. His-tag fused GPC3-Csub proteins allowed it to be purified by affinity chromatography method using the Nickel-nitrilotriacetic acid (Ni-NTA) column. High expression of GPC3-Csub was confirmed by Coomassie staining and western-blot. GPC3-Csub could be isolated with a Ni-NTA column and have a purity of about 90%.

关键词： Glypican-3 Affinity Chromatography Inclusion Body Liver Cancer

Effects of NaOH Concentrations on Properties of the Thermal Power Plant Ashes-Bricks by Alkaline Activation

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Journal of Wuhan University of Technology(Materials Science) 2020年第1期35卷 131-139页

作者： Ngo Si-Huy Le Thi thanh-Tam huynh Trong-Phuoc Department of Engineering and Technology Hong Duc UniversityNo.565Quang Trung StreetDong Ve WardThanh Hoa City 440000Viet Nam Department of Rural Technology College of Rural DevelopmentCan Tho UniversityCampus II3/2 StreetNinh Kieu DistrictCan Tho City 900000Viet Nam

The use of the thermal power plant ashes including fly ash(FA) and bottom ash(BA) for producing unfired building bricks(UBB) using sodium hydroxide(NaOH) solution as an alkaline activator was investigated. A low applied forming pressure of 0.5 MPa and various NaOH concentrations of 5, 8, 10, and 12 M were used for the preparation of brick samples with different solution-to-binder(S/B) ratios of 0.35 and 0.40. The bricks were subjected to various test programs with reflecting the effect of both NaOH concentrations and S/B ratios on the brick’s properties. The compressive strength, unit weight, ultrasonic pulse velocity, and thermal conductivity of bricks increased with increasing NaOH concentration, whereas the contrary trend was found with increasing S/B ratio. Also, the water absorption of bricks was observed to reduce with increasing NaOH concentration and decreasing S/B ratio. As the results, the combined utilization of both low forming pressure and coal power plant ashes can produce the UBBs with low unit weight, low heat conductivity, and acceptable strength and water absorption rate as stipulated by TCVN 6477-2016. Furthermore, the outcomes of chemical analysis and microstructure observation also demonstrate that a high concentration of the Na OH promoted the geopolymerization process. Notably, the use of NaOH solution of either 10 M or above is recommended for the production of UBBs, which are classified as grade M5.0 or higher.

关键词： unfired building brick fly ash bottom ash thermal power plant ashes sodium hydroxide solution low forming pressure

Combining SnO_(2-x)and g-C_(3)N_(4)nanosheets toward S-scheme heterojunction for high selectivity into green products of NO degradation reaction under visible light

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Journal of Materiomics 2022年第1期8卷 1-8页

作者： Pham Van Viet thanh-dat Nguyen Dai-Phat Bui Cao Minh Thi Faculty of Materials Science and Technology University of ScienceVNU-HCM227 Nguyen Van Cu StreetDistrict 5Ho Chi Minh City700000Viet Nam Vietnam National University-Ho Chi Minh City Thu Duc DistrictHo Chi Minh City700000Viet Nam Ho Chi Minh City University of Technology(HUTECH) 475A Dien Bien Phu StreetBinh Thanh DistrictHo Chi Minh City700000Viet Nam

NOx emissions cause many negative impacts on the living *** photocatalysis of semiconductors is superior for nitric oxide(NO)degradation due to their low redox *** this report,we combine SnO_(2-x)/g-C_(3)N_(4)heterojunction photocatalyst toward the high selectivity into green products under visible light *** show that SnO_(2-x)/g-C_(3)N_(4)heterojunction degraded 40.8%of NO,which is 1.6 times higher than that of g-C_(3)N_(4).In addition,the selectivity coefficient of SnO_(2-x)/g-C_(3)N_(4)is higher 3 times than both pure SnO_(2-x)and g-C_(3)N_(4).Furthermore,SnO_(2-x)/g-C_(3)N_(4)expresses a superior stability for NO photocatalytic-degradation after five *** scavenger trapping test results,and electron spin resonance(ESR)analysis also provide more understanding of the charge transfer mechanism of ***_(2-x)/g-C_(3)N_(4)heterojunction shows a high removal efficiency of NO gas,making it an up-and-coming environmental treatment candidate.

关键词： G-C_(3)N_(4) NO removal Oxygen vacancies Photocatalysis S-scheme

An Optimal Deep Learning Based Computer-Aided Diagnosis System for Diabetic Retinopathy

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Computers, Materials & Continua 2021年第3期66卷 2815-2830页

作者： Phong thanh Nguyen Vy Dang Bich huynh Khoa Dang Vo Phuong thanh Phan Eunmok Yang Gyanendra Prasad Joshi Department of Project Management Ho Chi Minh City Open UniversityHo Chi Minh City7000000Vietnam Department of Learning Material Ho Chi Minh City Open UniversityHo Chi Minh City7000000Vietnam Department of Convergence Science Kongju National UniversityGongju32588South Korea Department of Computer Science and Engineering Sejong UniversitySeoul05006South Korea

Diabetic Retinopathy(DR)is a significant blinding disease that poses serious threat to human vision *** and severity grading of DR are difficult processes to ***,it depends on ophthalmoscopically-visible symptoms of growing severity,which is then ranked in a stepwise scale from no retinopathy to various levels of DR *** paper presents an ensemble of Orthogonal Learning Particle Swarm Optimization(OPSO)algorithm-based Convolutional Neural Network(CNN)Model EOPSO-CNN in order to perform DR detection and *** proposed EOPSO-CNN model involves three main processes such as preprocessing,feature extraction,and *** proposed model initially involves preprocessing stage which removes the presence of noise in the input ***,the watershed algorithm is applied to segment the preprocessed *** by,feature extraction takes place by leveraging EOPSO-CNN ***,the extracted feature vectors are provided to a Decision Tree(DT)classifier to classify the DR *** study experiments were carried out using Messidor DR dataset and the results showed an extraordinary performance by the proposed method over compared methods in a considerable *** simulation outcome offered the maximum classification with accuracy,sensitivity,and specificity values being 98.47%,96.43%,and 99.02%respectively.

关键词： Diabetic retinopathy convolutional neural network classification image processing computer-aided diagnosis

Deep Learning Based Optimal Multimodal Fusion Framework for Intrusion Detection Systems for Healthcare data

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Computers, Materials & Continua 2021年第3期66卷 2555-2571页

作者： Phong thanh Nguyen Vy Dang Bich huynh Khoa Dang Vo Phuong thanh Phan Mohamed Elhoseny Dac-Nhuong Le Department of Project Management Ho Chi Minh City Open UniversityHo Chi Minh City700000Vietnam Department of Learning Material Ho Chi Minh City Open UniversityHo Chi Minh City700000Vietnam Faculty of Computers and Information Mansoura UniversityDakahlia Governorate35516Egypt Institute of Research and Development Duy Tan UniversityDanang550000Vietnam Faculty of Information Technology Duy Tan UniversityDanang550000Vietnam

data fusion is a multidisciplinary research area that involves different *** is used to attain minimum detection error probability and maximum reliability with the help of data retrieved from multiple healthcare *** generation of huge quantity of data from medical devices resulted in the formation of big data during which data fusion techniques become *** medical data is a crucial issue of exponentially-pacing computing world and can be achieved by Intrusion Detection Systems(IDS).In this regard,since singularmodality is not adequate to attain high detection rate,there is a need exists to merge diverse techniques using decision-based multimodal fusion *** this view,this research article presents a new multimodal fusion-based IDS to secure the healthcare data using *** proposed model involves decision-based fusion model which has different processes such as initialization,pre-processing,Feature Selection(FS)and multimodal classification for effective detection of *** FS process,a chaotic Butterfly Optimization(BO)algorithmcalled CBOA is *** the classic BO algorithm offers effective exploration,it fails in achieving faster *** order to overcome this,i.e.,to improve the convergence rate,this research work modifies the required parameters of BO algorithm using chaos ***,to detect intrusions,multimodal classifier is applied by incorporating three Deep Learning(DL)-based classification ***,the concepts like Hadoop MapReduce and Spark were also utilized in this study to achieve faster computation of big data in parallel computation *** validate the outcome of the presented model,a series of experimentations was performed using the benchmark NSLKDDCup99 dataset *** proposed model demonstrated its effective results on the applied dataset by offering the maximum accuracy of 99.21%,precision of 98.93%and detection rate of 99.59%.The results assured the betterm

关键词： Big data data fusion deep learning intrusion detection bio-inspired algorithm spark

Novel Deletion in Exon 7 of Betaine Aldehyde Dehydrogenase 2(BADH2)

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Rice science 2023年第2期30卷 104-112,I0020-I0030页

作者： VAN Quoc Giang huynh Ky NGUYEN Chau thanh Tung NGUYEN Loc Hien NGUYEN van Manh NGUYEN Nhut thanh VO Cong thanh SWEE Keong Yeap College of Agriculture Can Tho UniversityCan Tho 92000Vietnam Department of Sciences and Technology of Long An Province Long An 850000Vietnam China-Association of Southeast Asian Nations College of Marine Sciences Xiamen University MalaysiaSepang 49000SelangorMalaysia

The fragrance of rice is one of the premium characteristics that breeders want to include in rice varieties due to the higher market value. Nucleotide deletions in exons 2(7 bp) and 7(8 bp) of Betaine Aldehyde Dehydrogenase 2(BADH2) are associated with fragrance in rice. In this study, a new 13 bp deletion in exon 7 of the BADH2 gene was discovered in the Nang Thom Cho Dao(NTCD) variety, and the mutation has been closely related to the genetic background of indica subspecies through the Bayesian phylogenetic approach and haplotype network analysis of the 3 000 Rice Genomes Project. In addition, a set of functional markers(EX07-13F, EX07-13RN, and EX07-13RM) identified the 13 bp deletion only within NTCD(no amplified band) compared with both non-aromatic and other aromatic rice varieties(110 bp band). The deletion of 13 bases instead of 8 bases in exon 7 of BADH2 caused a premature stop codon, which down-regulated the expression of the BADH2 transcript while associated with up-regulation of OsP5CS and the high amount of 2-acetyl-1-pyrroline. It is potential to use the deletion in exon 7 of the BADH2 gene as a novel marker for adulteration and breeding of fragrant rice varieties, particularly for NTCD.

关键词： novel deletion BADH2 fragrant rice functional marker

One-step hydrothermal synthesis of Sn-doped α-Fe_(2)O_(3) nanoparticles for enhanced photocatalytic degradation of Congo red

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Journal of Semiconductors 2022年第12期43卷 22-31页

作者： Van Nang Lam Thi Bich Vu Quang dat Do Thi thanh Xuan Le Tien Dai Nguyen T-thanh-Bao Nguyen Hoang Tung Do Thi Tu Oanh Nguyen Department of Natural Sciences Hoa Lu UniversityNinh NhatNinh Binh CityViet Nam Institute of Theoretical and Applied Research Duy Tan UniversityHanoi 100000Viet Nam Faculty of Natural Sciences Duy Tan UniversityDa Nang 550000Vietnam Institute of Physics Vietnam Academy of Science and Technology10 Dao TanBa DinhHanoiVietnam Institute of Materials Science Vietnam Academy of Science and Technology18 Hoang Quoc VietCaugiayHanoiVietnam

We report on the synthesis of Sn-doped hematite nanoparticles(Sn-α-Fe_(2)O_(3) NPs)by the hydrothermal *** prepared Sn-α-Fe_(2)O_(3) NPs had a highly pure and well crystalline rhombohedral phase with an average particle size of 41.4 *** optical properties of as-synthesizedα-Fe_(2)O_(3) NPs show a higher bandgap energy(2.40-2.57 eV)than that of pure bulkα-Fe_(2)O_(3)(2.1 eV).By doping Sn intoα-Fe_(2)O_(3) NPs,the Sn-doped hematite was observed a redshift toward a long wavelength with in-creasing Sn concentration from 0%to 4.0%.The photocatalytic activity of Sn-dopedα-Fe_(2)O_(3) NPs was evaluated by Congo red(CR)dye *** degradation efficiency of CR dye using Sn-α-Fe_(2)O_(3) NPs catalyst is higher than that of pureα-Fe_(2)O_(3) *** highest degradation efficiency of CR dye was 97.8%using 2.5%Sn-dopedα-Fe_(2)O_(3) NPs catalyst under visible-light *** results suggest that the synthesized Sn-dopedα-Fe_(2)O_(3) nanoparticles might be a suitable approach to develop a photocatalytic degradation of toxic inorganic dye in wastewater.

关键词： α-Fe_(2)O_(3)nanoparticles Sn Congo red photocatalytic properties photodegradation

Minimizing Warpage for Macro-Size Fused Deposition Modeling Parts

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Computers, Materials & Continua 2021年第9期68卷 2913-2923页

作者： thanh Thuong huynh Tien V.T.Nguyen Quoc Manh Nguyen Trieu Khoa Nguyen Department of Mechanical Engineering Can Tho UniversityCampus IICan ThoVietnam Faculty of Mechanical Technology Industrial University of Ho Chi Minh CityHo Chi Minh70000Vietnam Mechanical Engineering Department National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Faculty of Mechanical Engineering Hung Yen University of Technology and EducationHung Yen16000Vietnam

In this study,we investigated warpage and corner lifting minimization for three-dimensional printed parts generated by macro-size fused deposition modeling(FDM).First,the reasons for warpage were theoretically *** approach revealed that the thermal deformation and differential volumetric shrinkage of the extruded molten plastic resulted in warpage of FDM *** addition,low adhesion between the deposited model and the heated or non-heated printing bed may intensify warpage *** a next step,initial small-size and medium-size models were used to identify parameters to manage and minimize warpage in a way that would reduce material consumption and running ***,a macro-size model was built to experimentally investigate and verify the technical solutions to minimize the warpage of FDM *** conclusion,an improved part with reduced warpage was efficiently produced after detailed consideration of thermal effects and adhesion *** exists to widen the application scope of FDM technology in manufacturing for processes like thermoforming that involve mold core fabrication with *** technology,which has applications not only in mechanical engineering but also in related engineering fields,is convenient and could readily be applied to practical manufacturing industries.

关键词： Fused deposition modeling corner lifting volumetric shrinkage thermal deformation acrylonitrile butadiene styrene filament