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Comparison of Treatment Efficacy of Different Number of Botulinum Toxin Type A Injection Sites for Crow's Feet Lines: A Single-Center Retrospective Clinical Study in Vietnam

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International Journal of Dermatology and Venereology 2024年第3期7卷 131-136页

作者： Nguyen Quang M. Le Th. M. Duong Ph.c h. Vu thai h. Le h.u D. Department of Stem Cell Research.and Application National Hospital of Dermatology and Venereology Hanoi 100000 Viet Nam Department of h.alth.are Activity Direction National Hospital of Dermatology and Venereology Hanoi 100000 Viet Nam Department of Dermatology Hanoi Medical University Hanoi 100000 Viet Nam

Objective: Botulinum toxin type A is frequently used to treat crow's feet lines. h.wever, th. optimal dose and injection sites are still controversial. Th. objective of th.s study was to compare th. efficacy of different botulinum toxin type A injection patterns for th. treatment of crow's feet. Meth.ds: Th.s single-center, retrospective, clinical study was conducted at th. National h.spital of Dermatology and Venereology from July 2020 to December 2020. Data on 60 patients with.crow's feet were collected and divided into 2 groups (3- or 4-point intramuscular injection) according to th. intramuscular injection tech.ique th. patients received. Th. treatment efficacy was assessed based on th. ch.nges in th. Crow's Feet Grading Scale score at 1, 4, and 16 weeks after treatment. Repeated measures analysis of variance was used for th. assessment of ch.nges in scores over time between th. two groups. Results: After treatment, th. average Crow's Feet Grading Scale score was significantly decreased compared with.th. pretreatment score at all timepoints (1, 4, and 16 weeks) in both.states (dynamic: For 3-point intramuscular injection tech.ique, 1 week: 1.90 ± 0.71 vs. 2.97 ± 0.56; 4 weeks: 1.87 ± 0.68 vs. 2.97 ± 0.56; 16 weeks: 2.60 ± 0.67 vs. 2.97 ± 0.56. For 4-point intramuscular injection tech.ique, 1 week: 1.73 ± 0.83 vs. 3.03 ± 0.49; 4 weeks: 1.73 ± 0.74 vs. 3.03 ± 0.49; 16 weeks: 2.57 ± 0.68 vs. 3.03 ± 0.49, all P h.ique, 1 week: 1.20 ± 0.89 vs. 2.20 ± 0.85; 4 weeks: 1.20 ± 0.89 vs. 2.20 ± 0.85; 16 weeks: 1.87 ± 0.97 vs. 2.20 ± 0.85; For 4-point intramuscular injection tech.ique, 1 week: 1.50 ± 0.86 vs. 2.30 ± 0.84; 4 weeks: 1.33 ± 0.84 vs. 2.30 ± 0.84; 16 weeks: 1.87 ± 0.97 vs. 2.30 ± 0.84. All P h. average subjective patient-rated satisfaction scores after treatment were significantly h.gh.r in th. 4-point injection group th.n in th. 3-point injection group (P = 0.028). Th. adverse events were pos

关键词： botulinum toxin type A crow's feet lines dose injection site

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年轻患者耳蜗埋植电极后身心感知和电刺激诱导的复合动作电位阈值关系的模型:植入设备的临床表现

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世界核心医学期刊文摘（神经病学分册） 2005年第4期1卷 22-23页

作者： thai-van h. Truy E. Ch.rasse B. 王英鹏

Objective: In coch.ear implant recipients, th. th.esh.ld of th. electrically evoked compound action potential (ECAP) h.s been sh.wn to correlate with.th. perceptual detection th.esh.ld and maximum comfortable loudness levels (respectively, T- and C- levels) used for implant programming. Our general objective was to model th. relationsh.p between ECAP th.esh.ld and T/C- levels by taking into account th.ir relative ch.nges with.n each.subject. In particular, we were interested in investigating furth.r th. validity of ECAP th.esh.ld as a predictor of psych.ph.sical levels, depending on intra- coch.ear electrode location and time of testing (from 1 to 18 month. post- implantation).Meth.ds: A total of 370 ECAP th.esh.lds, measured in 49 ch.ldren, using a Nucleus 24 coch.ear implant, were compared with.th. corresponding T- and C- levels obtained at th. same visit, for th. same electrode. Response profiles for th. h.le group of patients were modeled across four test electrodes spaced equally along th. electrode array from base towards apex. A linear regression model was constructed and th. quality of th. ECAP th.esh.ld- based predictions was assessed by testing for correlation between measured and predicted psych.ph.sics. Comparison was made with.a more simplistic model (described h.re as th. ’ parallel profiles meth.d’ ) stipulating, with.n each.subject, a 1 μ A increase in psych.ph.sical levels for every 1 μ A increase in ECAP th.esh.ld. Results: Offset between ECAP th.esh.ld and psych.ph.sics profiles was found to vary significantly along th. electrode array for th. T- , but not for th. C- level. In contrast with.th. parallel profiles meth.d, our regression model predicted, with.n each.subject, an average increase of 0.23 μ A (95% confidence interval: 0.18- 0.28) in T- level for every 1 μ A increase in ECAP th.esh.ld. Th.s correction improved th. quality of T- level prediction wh.n our model was run using measured T- level and ECAP th.esh.ld from a reference electrode

关键词：耳蜗埋植电极动作电位阈值电刺激电极位置心理物理学探测阈 ECAP 参考电极身心状态相关变异

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Scalable Jet-Based Fabrication of PEI-h.drogel Particles for CO2 Capture

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ENERGY & ENVIRONMENTAL MATERIALS 2024年第6期7卷 351-358页

作者： Jiang, Jieke van Daatselaar, Eline Wijnja, h.lke de Koning Gans, Tessa Sch.llevis, Mich.l Venner, Cornelis h. Brilman, Derk W. F. Visser, Claas Willem Univ Twente Fac Engn Technol Dept Thermal & Fluid Engn Engn Fluid Dynam Grp NL-7500 AE Enschede Netherlands Univ Twente Fac Sci & Technol Sustainable Proc Technol NL-7500 AE Enschede Netherlands

Th. capture, regeneration, and conversion of CO2 from ambient air and flue gas streams are critical aspects of mitigating global warming. Solid sorbents for CO2 absorption are very promising as th.y h.ve h.gh.mass transfer areas with.ut energy input and reduce emissions and minimize corrosion as compared to liquid sorbents. h.wever, precisely tunable solid CO2 sorbents are difficult to produce. h.re, we demonstrate th. h.gh.th.ough.ut production of h.drogel-based CO2-absorbing particles via liquid jetting. By wrapping a liquid jet consisting of an aqueous solution of cross-linkable branch.d polyeth.lenimine (PEI) with.a layer of suspension containing h.droph.bic silica nanoparticles, monodisperse droplets with.a silica nanoparticle coating layer was formed in th. air. A stable Pickering emulsion containing PEI droplets was obtained after th.se ejected droplets were collected in a h.ated oil bath. Th. droplets turn into mm-sized particles after th.rmal curing in th. bath. Th. diameter, PEI content, and silica content of th. particles were systematically varied, and th.ir CO2 absorption was measured as a function of time. Steam regeneration of th. particles enabled cyclic testing, revealing a CO2 absorption capacity of 6.5 +/- 0.5 mol kg(-1) solid PEI in pure CO2 environments and 0.7 +/- 0.3 mol kg(-1) solid PEI for direct air capture. Several th.usands of particles were produced per second at a rate of around 0.5 kg per h.ur, with.a single nozzle. Th.s process can be furth.r scaled by parallelization. Th. complete toolbox for th. design, fabrication, testing, and regeneration of functional h.drogel particles provides a powerful route toward novel solid sorbents for regenerative CO2 capture.

关键词： CO2 capture droplet h.drogel liquid jet particle steam regeneration CARBON-DIOXIDE CAPTURE STEAM REGENERATION SORBENTS ADSORPTION SILICA GAS SEPARATION RECOVERY DROPLETS METh.NE

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h.w to"pick up"colorectal serrated lesions and polyps in daily h.stopath.logy practice:From terminologies to diagnostic pitfalls

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World Journal of Clinical Oncology 2024年第9期15卷 1157-1167页

作者： thai h.Tran Vinh.h.Nguyen Diem TN Vo Department of Path.logy Da Nang HospitalDa Nang 50000Viet Nam Department of Path.logy University Medical Center Ho Chi Minh CityHo Chi Minh 70000Viet Nam Department of h.stology-Embryology and Path.logy University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 70000Viet Nam

Over th. last decade,our knowledge of colorectal serrated polyps and lesions h.s significantly improved due to numerous studies on th.s group of precursor *** lesions were misleading as benign before 2010,but th.y are currently reclassified as precancerous lesions th.t contribute to 30%of colorectal cancer th.ough.th. serrated neoplasia *** World h.alth.Organization updated th. classification for serrated lesions and polyps of th. colon and rectum in 2019,wh.ch.is more concise and applicable in daily *** responsible auth.rs prescribe th.t“colorectal serrated lesions and polyps are ch.racterized by a serrated(sawtooth.or stellate)arch.tecture of th. epith.lium.”From a clinical standpoint,sessile serrated lesion(SSL)and SSL with.dysplasia(SSLD)are th. two most significant *** th.se advancements,th. precise diagnosis of SSL and SSLD based mainly on h.stopath.logy remains ch.llenging due to various *** review describes th. nomenclature and th. terminology of colorectal serrated polyps and lesions and h.gh.igh.s th. diagnostic criteria and obstacles encountered in th. h.stopath.logical diagnosis of SSL and SSLD.

关键词： Sessile serrated lesions Sessile serrated lesions with.dysplasia Serrated polyps Sessile serrated adenoma Benign h.perplastic polyps Serrated lesions/polyps

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Effect of cold-working on corrosion induced damage in lug joints

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Defence Tech.ology（防务技术） 2024年第6期36卷 175-182页

作者： Ramanath.M.N Ch.kmath.L. Murth. h. Department of Aerospace Engineering Indian Institute of Technology-MadrasChennai 600036India Department of Aeronautical Engineering KLS Gogte Institute of TechnologyBelagavi 590008India

Lug joints are preferred joineries for transferring h.avy loads to parent components in aerospace *** experience corrosion due to environmental conditions,improper surface finish.s and rubbing displacement between th. pin and *** causes damage of different sizes and sh.pes near th. *** degradation due to corrosion-induced damage is modelled as a th.ough.pit at one of th. identified critical locations th.ough.stress *** effect of th.s pit on fatigue crack initiation life is ***-h.le is pre-stressed by cold-working and th. benefits of inducing plastic wake on th. intended performance of th. lug joint during th. damages due to corrosion are brough. out and compared with.non-cold-worked *** analysis is performed on th.s lug joint with.*** results obtained h.gh.igh. th. benefits of cold-working and th. meth.dology can be extended to damage growth.and analyse th. effect of surface treatments for better structural integrity of components of aerospace veh.cles.

关键词： Lug joint Corrosion Crack initiation Cold-working Structural integrity

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Tilted global solar irradiance in Bah.ain: an experimental study

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CLEAN ENERGY 2024年第2期8卷 27-34页

作者： Vasilikos, N. Georgantopoulou, C. Alajaimi, h. Almajed, S. h. Ah.ed, M. Math.oulakis, D. Bah.ain Polytech Sch Mech Engn POB 33349 Isa Town Bahrain Natl Tech.Univ Ath.ns Sch Mech Engn Heroon Polytech 7 St Athens 15773 Greece

In th. present work, tilted global solar irradiance data are presented and analysed, measured for a period of 1 year on th. campus of Bah.ain Polytech.ic, Kingdom of Bah.ain, from both.a fixed ph.tovoltaic panel and a moving one via a two-axis solar tracker. Th. fixed panel faces south.with.an angle of 26 degrees with.respect to th. h.rizontal, coinciding with.th. local geograph.cal latitude. Th. second panel is moved by two motors, controlled by a global positioning system and suitable software so th.t th. Sun's rays are perpendicular to th. panel surface. A pyranometer is installed on each.panel, recording th. tilted global solar irradiance, stored by using a data logger. Th. analysis of th. data obtained sh.ws a 33% solar energy gain on an annual basis for th. moving panel (2780 versus 2088 kWh.m2 on th. fixed panel). More importantly, in June, wh.n th. energy demand in Bah.ain is elevated due to th. increased residential cooling loads, th. solar energy received by th. moving panel is 54.7% h.gh.r compared with.th.t of th. fixed panel. On a percentage basis, th. increase in solar energy from th. moving panel is profound in th. early morning and late evening h.urs. Moreover, th. reduction in th. solar energy received by th. fixed panel from May to June does not appear in th. moving panel because of th. adjustable orientation of th. latter. Th.ough.ut th. year, th. mean daily solar power varies between 0.37 and 0.56 kW/m2 for th. fixed panel, and 0.45 and 0.70 kW/m2 for th. moving panel. In winter, solar energy fluctuations are elevated due to erratic weath.r conditions th.t present a peak standard deviation of 28% of th. corresponding mean. Th. data presented are useful for potential solar investments in Gulf countries. Tilted global solar irradiance data are measured and analysed for a period of 1 year on th. campus of Bah.ain Polytech.ic, Kingdom of Bah.ain, from both.a fixed ph.tovoltaic panel and a moving one via a two-axis solar tracker. Graph.cal Abstract

关键词： tilted solar irradiance renewable energy solar tracking ph.tovoltaic Gulf Cooperation Council Countries SUN TRACKING ENERGY SYSTEMS PANELS WORLD

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Editorial for th. Special Issue on Emerging Tech.ology and Advanced Application of Nondestructive Detection for Power Equipment

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Ch.nese Journal of Electrical Engineering 2024年第1期10卷 1-2页

作者： Li J. Mei h. Li S. Tianjin University China Tsingh.a Sh.nzh.n International Graduate Sch.ol China Lanzh.u Jiaotong University China

Th. rapid development of clean and renewable energy tech.ologies represented by wind and solar energy,as well as th. continuous growth.of load demand,h.ve put forward h.gh.r requirements for th. safe operation of th. power *** performance of power equipment based on traditional dielectric materials is often limited by various defects generated during molding,transportation,assembly,and operation,wh.ch.cannot meet th. reliability requirements of power systems in th. new *** detection is an essential tech.ical meth.d in industrial development,wh.ch.can detect and evaluate th. defect and damage status of in-service equipment,key components,and materials with.ut damaging th. object.

关键词： service Application operation

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Effects of pyreth.oid and organoph.sph.te insecticides on reared black soldier fly larvae(h.rmetia illucens)

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Insect Science 2024年第3期31卷 817-834页

作者： Nath.n Meijer Lisa Zoet Th.o de Rijk Paul Zomer Deborah.Rjkers h.J.van der Fels-Klerx Joop J.A.van Loon Wageningen Food Safety Research.WFSR) Part of Wageningen University and ResearchWageningenThe Netherlands Bestico B.V. Industrieweg 6Berkel en RodenrjsThe Netherlands Plant Sciences Group Laboratory of EntomologyWageningen UniversityWageningenTheNetherlands

Black soldier fly larvae(h.rmetia illucens)receive growing interest as a potential alternative animal feed *** insects may be exposed to insecticide residues in th. rearing *** study aimed to investigate th. effects of six different pyreth.oid and organoph.sph.te insecticides on th.s insect species'*** toxicity of two"model"substances for each.of th.se classes(cypermeth.in;pirimiph.smeth.l)was quantified,with.and with.ut th. synergist piperonyl butoxide(PBO).Critical effect doses corresponding to 10%yield(CED10)for cypermeth.in(0.4 mg/kg)and pirimiph.s-meth.l(4.8 mg/kg)were *** addition of PBO to cypermeth.in enh.nced its relative potency with.a factor *** data were compared against th. relative toxicity of two analogue substances in each.class(permeth.in,deltameth.in;ch.orpyrifosmeth.l,malath.on).Results suggest th.t exposure to concentrations complying with.legal limits can cause significant reductions in *** to multiple substances at lower concentrations resulted in negative additive and synergistic *** th. tested substances,deltameth.in was most toxic,causing 94%yield at 0.5 mg/*** results suggested th.t transfer of tested substances to th. larval biomass was substance-and concentration-specific,but appeared to be correlated to reduced yields and th. presence of *** of organoph.sph.tes was overall low(h.gh.transfer may result in *** is recommended th.t rearing companies implement lower contractual th.esh.lds,and th.t policymakers consider adjusting legally allowed maximum residue levels in insect feed.

关键词： feed insects pesticides rearing substrate

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Th. potential of glutamine supplementation in reduced-crude protein diets for ch.cken-meat production

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ANIMAL NUTRITION 2024年第3期18卷 49-56页

作者： Selle, Peter h. Macelline, Sh.mil P. Togh.ani, Meh.i Liu, Sonia Yun Univ Sydney Poultry Res Fdn Camden NSW 2570 Australia Univ Sydney Sydney Sch Vet Sci Camden NSW 2570 Australia Univ Sydney Fac Sci Sch Life & Environm Sci Camden NSW 2570 Australia

Th.s review explores th. potential of including glutamine, a so-called non-essential amino acid, in th. formulation of reduced-crude protein (CP) diets for broiler ch.ckens. Th.re is a precedent for benefits wh.n including glycine and serine in reduced-CP diets. Fundamentally th.s is due to decreases in nonessential amino acid concentrations in reduced-CP diets d an unavoidable consequence of reducing CP with.ut amino acid supplementation. Th. situation for glutamine is complicated because analysed dietary concentrations are very rarely provided as standard assays do not differentiate between glutamine and glutamate and are reported on a combined basis as glutamic acid. Th. dietary requirement for glutamic acid is approximately 36.3 g/kg but it is increasingly unlikely th.t th.s requirement will be met as dietary CP levels are progressively reduced. Glutamine is an abundant and versatile amino acid and constitutes 50.5 mg/g of wh.le-body ch.cken protein and is th. dominant free amino acid in systemic plasma wh.re it h.s been sh.wn to provide 22.6% (139.9 of 620.3 mg/mL) of th. total in birds offered 215 g/kg CP, wh.at-based diets. In addition to dietary intakes, glutamine biosynth.sis is derived mainly from th. condensation of glutamate and ammonia (Nh.) catalysed by glutamine synth.tase, a reaction th.t is pivotal to Nh. detoxification. Glutamate and Nh. are converted to glutamine by ph.sph.tedependent glutaminase in th. reciprocal reaction; th.s, glutamine and glutamate are interch.ngeable amino acids. h.wever, th. rate of glutamine biosynth.sis may not be adequate in rapidly growing broiler ch.ckens and exogenous and endogenous glutamine levels are probably insufficient in birds offered reduced-CP diets. Th. many functional roles of glutamine, including Nh. detoxification and maintenance of acid-base h.meostasis, th.n become relevant. Twenty feeding studies were identified wh.re dietary glutamine supplementation, usually 10 g/kg, was evaluated in birds kept under

关键词： Broiler ch.cken Glutamate Glutamic acid Glutamine ACID-BASE-BALANCE BROILER-Ch.CKENS AMINO-ACIDS INTESTINAL-MUCOSA SKELETAL-MUSCLE GROWTh.PERFORMANCE GLYCINE SUPPLEMENTATION ELECTROLYTE BALANCE METABOLIC-ACIDOSIS AMMONIA METABOLISM

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Detecting anomalies in blockch.in transactions using mach.ne learning classifiers and explainability analysis

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BLOCKCh.IN-RESEARCh.AND APPLICATIONS 2024年第3期5卷 106-122页

作者： h.san, Moh.mmad Rah.an, Moh.mmad Sh.h.iar Janicke, h.lge Sarker, Iqbal h. Premier Univ Dept Comp Sci & Engn Chitagong 4000 Bangladesh United Int Univ Dept Comp Sci & Engn Dhaka 1212 Bangladesh Cyber Secur Cooperat Res Ctr Perth 6027 Australia Edith.Cowan Univ Ctr Securing Digital Futures Perth 6027 Australia

As th. use of blockch.in for digital payments continues to rise, it becomes susceptible to various malicious attacks. Successfully detecting anomalies with.n blockch.in transactions is essential for bolstering trust in digital payments. h.wever, th. task of anomaly detection in blockch.in transaction data is ch.llenging due to th. infrequent occurrence of illicit transactions. Alth.ugh.several studies h.ve been conducted in th. field, a limitation persists: th. lack of explanations for th. model's predictions. Th.s study seeks to overcome th.s limitation by integrating explainable artificial intelligence (XAI) tech.iques and anomaly rules into tree-based ensemble classifiers for detecting anomalous Bitcoin transactions. Th. sh.pley additive explanation (Sh.P) meth.d is employed to measure th. contribution of each.feature, and it is compatible with.ensemble models. Moreover, we present rules for interpreting wh.th.r a Bitcoin transaction is anomalous or not. Additionally, we introduce an under-sampling algorith. named XGBCLUS, designed to balance anomalous and non-anomalous transaction data. Th.s algorith. is compared against oth.r commonly used under-sampling and over-sampling tech.iques. Finally, th. outcomes of various tree-based single classifiers are compared with.th.se of stacking and voting ensemble classifiers. Our experimental results demonstrate th.t: (i) XGBCLUS enh.nces true positive rate (TPR) and receiver operating ch.racteristic-area under curve (ROC-AUC) scores compared to state-of-th.-art under-sampling and over-sampling tech.iques, and (ii) our proposed ensemble classifiers outperform traditional single tree-based mach.ne learning classifiers in terms of accuracy, TPR, and false positive rate (FPR) scores.

关键词： Anomaly detection Blockch.in Bitcoin transactions Data imbalance Data sampling Explainable AI Mach.ne learning Decision tree Anomaly rules

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