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Spray Pyrolyzed TiO2 Embedded Multi-Layer Front Contact Design for High-Efficiency Perovskite Solar Cells

Nano-Micro Letters 2021年第2期13卷 262-278页

作者： Md.Shahiduzzaman Mohammad Ismail Hossain Sem Visal tetsuya Kaneko Wayesh Qarony Shinjiro Umezu Koji Tomita Satoru Iwamori Dietmar Knipp Yuen Hong Tsang Md.Akhtaruzzaman Jean-Michel Nunzi tetsuya taima Masao Isomura Nanomaterials Research Institute(NanoMaRi) Kanazawa UniversityKakumaKanazawa 920-1192Japan Department of Applied Physics and Materials Research Center The Hong Kong Polytechnic UniversityHung HomKowloonHong KongP.R.China Research Institute of Science and Technology Tokai UniversityKitakanameHiratsuka 259-1292Japan Department of Chemistry School of ScienceTokai UniversityKitakanameHiratsuka 259-1292Japan Graduate School of Engineering Tokai UniversityKitakanameHiratsuka 259-1292Japan Department of Modern Mechanical Engineering Waseda University3-4-1 OkuboShinjukuTokyo 169-8555Japan Solar Energy Research Institute The National University of Malaysia43600 BangiSelangorMalaysia Department of Materials Science and Engineering City University of Hong KongKowloonHong KongP.R.China Geballe Laboratory for Advanced Materials Department of Materials Science and EngineeringStanford UniversityStanfordUSA Department of Physics Engineering Physics and AstronomyQueens UniversityKingstonONCanada

The photovoltaic performance of perovskite solar cells(PSCs)can be improved by utilizing efficient front ***,it has always been a significant challenge for fabricating high-quality,scalable,controllable,and cost-effective front *** study proposes a realistic multi-layer front contact design to realize efficient single-junction PSCs and perovskite/perovskite tandem solar cells(TSCs).As a critical part of the front contact,we prepared a highly compact titanium oxide(TiO2)film by industrially viable Spray Pyrolysis Deposition(SPD),which acts as a potential electron transport layer(ETL)for the fabrication of *** and reproducibility of the TiO2 ETL were discreetly investigated while fabricating a set of planar *** the front contact has a significant influence on the optoelectronic properties of PSCs,hence,we investigated the optics and electrical effects of PSCs by three-dimensional(3D)finite-difference time-domain(FDTD)and finite element method(FEM)rigorous *** investigation allows us to compare experimental results with the outcome from ***,an optimized single-junction PSC is designed to enhance the energy conversion efficiency(ECE)by>30% compared to the planar reference ***,the study has been progressed to the realization of all-perovskite TSC that can reach the ECE,exceeding 30%.Detailed guidance for the completion of high-performance PSCs is provided.

关键词： Perovskite Tandem solar cells Spray pyrolysis deposition TiO2 compact layer Optics and optimization Electrical characteristic

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Activity and bioavailability of tepotinib for leptomeningeal metastasis of NSCLC with MET exon 14 skipping mutation

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Cancer Communications 2021年第1期41卷 83-87页

作者： Hisashi Tanaka Kageaki taima Tomonori Makiguchi Junichi Nakagawa Takenori Niioka Sadatomo Tasaka Department of Respiratory Medicine Hirosaki University Graduate School of MedicineAomori 036-8562Japan Department of Pharmacy Hirosaki University HospitalAomori 036-8562Japan

Tepotinib is a key drug for cancer patients with mesenchymal-epithelial transition receptor tyrosine kinase proto-oncogene(MET)exon 14 skipping ***,its bioavailability in the cerebrospinal fluid(CSF)in humans has not been fully ***,information about the efficacy of tepotinib in patients with leptomeningeal metastasis is ***,we present the case of a 56-year-old man who was diagnosed with lung adenocarcinoma with MET exon 14 skipping *** was urgently hospitalized due to leptomeningeal *** administered tepotinib 500 mg/day as the second-line therapy and observed improvement in leptomeningeal metastasis and performance *** tepotinib concentrations reached 1,648 ng/mL in the plasma and 30.6 ng/mL in the CSF,with a penetration rate(CSF/plasma)of 1.83%.These demonstrate tepotinib could achieve a high rate of central nervous system transition and could be effective against leptomeningeal metastasis.

关键词： cerebrospinal fluid IC50 leptomeningeal metastasis MET exon 14 skipping mutation non-small cell lung carcinoma performance status pharmacokinetics tepotinib

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Expression of liver insulin-like growth factor 1 gene and its serum level in patients with diabetes

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World Journal of Gastroenterology 2004年第2期10卷 255-259页

作者： Jian-BoLi Cheng-YaWang Jia-WeiChen Zhen-QingFeng Hong-taima DepartmentofEndocrinology FirstAffiliatedHospitalofNanjingMedicalUniversityNanjing210029JiangsuProvinceChina MolecularLaboratory FirstAffiliatedHospitalofNanjingMedicalUniversityNanjing210029JiangsuProvinceChina DepartmentofPathology NanjingMedicalUniversityNanjing210029JiangsuProvinceChina

AIM:To explore the effect of diabetic duration and blood glucose level on insulin like growth factor 1(IGF-1) gene expression and serum IGF-1 ***: Diabetes was induced into Sprague Dawley rats by alloxan and then the rats were subdivided into different groups with varying blood glucose level and diabetic *** parameters were measured as follows:IGF-1 mRNA by reverse transcriptase-polymerase chain reaction (RT-PCR),IGF-1 peptide and serum IGF-1 concentration by enzymelinked immunosorbent assay (ELISA).RESULTS:During early diabetic stage (week 2),in comparison with normal control group (NC), IGF-1 mRNA(1.17±0.069 vs 0.79±0.048, P<0.001;1.17±0.069 vs 0.53±0.023, P<0.0005, respectively), IGF-1 peptide contents[(196.66±14.9)ng·mg^-1 vs(128.2±11.25)ng·mg^-1,P<0.0005;(196.66±14.9)ng·mg^-1 vs(74.43±5.33)ng·mg^-1, P<0.0001,respectively] were reduced in liver tissues of diabetic *** IGF-1 gene downregulation varied with glucose control level of the diabetic state,and deteriorated gradually further with duration of *** month 6, hepatic tissue IGF-1mRNA was 0.71±0.024 vs 1.12±0.056,P<0.001;0.47±0.021 vs 1.12±0.056, P<0.0005,***-1 peptide was (114.35±8.09) ng·mg^-1 vs (202.05±15.73)ng·mg^-1,P<0.0005; (64.58±3.89) ng·mg^-1 vs(202.05±15.73)ng·mg^-1,P<0.0001 respectively. Serum IGF-1 was also lowered in diabetic group with poor control of blood *** week 2, serum IGF-1 concentrations were (371.0±12.5)ng·mg^-1 vs(511.2±24.7)ng·mg^-1,P<0.0005, (223.2±9.39)ng·mg^-1 vs(511.2±24.7)ng·mg^-1, P<0.0001 respectively. By month 6, (349.6±18.62)ng·mg^-1 vs(520.7±26.32)ng·mg^-1,P<0.0005, (188.5±17.35 vs520.7±26.32)ng·mg^-1,P<0.0001,respectively. Serum IGF-1 peptide change was significantly correlated with that in liver tissue (r=-0.99, P<0.001).Furthermore,No difference was found in the above parameters between diabetic rats with euglycemia and non-diabetic control ***: The influence of diabetic status on IGF-1 gene expression in li

关键词：胰岛素样生长因子1 基因表达血清学检查糖尿病逆转录聚合酶链反应 ELISA 动物模型

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面向约旦《新实用汉语课本》本土化汉语教材研究

面向约旦《新实用汉语课本》本土化汉语教材研究

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作者：小曼（taima Alshdaifat）天津大学

学位级别：硕士

约旦汉语教学虽已有十年历史,但至今仍然处于发展阶段,主要在于约旦缺乏汉语教学的基本条件,例如:缺乏适合该地区的汉语教材。约旦大学是约旦最早开设汉语课程的学校,使用的教材为《新实用汉语课本》,但该教材本身存在一些问题,如该教... 详细信息

约旦汉语教学虽已有十年历史,但至今仍然处于发展阶段,主要在于约旦缺乏汉语教学的基本条件,例如:缺乏适合该地区的汉语教材。约旦大学是约旦最早开设汉语课程的学校,使用的教材为《新实用汉语课本》,但该教材本身存在一些问题,如该教材与约旦学生需求存在不匹配的地方,而且约旦大学与约旦其他教授汉语学校的老师们过分依赖《新实用汉语课本》教材等。近几年本土化教材或国别化教材编写成了汉语教学研究最热门的话题之一,而至今还没有一本针对阿拉伯地区的本土化汉语教材,因此笔者决定研究约旦地区当地文化与约旦汉语学习者特征,研究该地区本土化汉语教材的特点,并通过自己的经验,采用调查问卷与访谈的方法收集第一手资料,笔者根据约旦汉语学习者的需求对《新实用汉语课本》进行改良,形成适合约旦汉语学习者本土化汉语教材。为完成本论文的工作需求及提供第一手材料,笔者已使用过:调查问卷法、访谈法和文献研究法,以研究约旦汉语学习者的特点、对学汉语的需求、学习方法等约旦文化与社会本地信息,便于编写约旦地区本土化汉语教材。同时,笔者研究了目前约旦大学和约旦其他有开设汉语教育课程的学校目前所使用的汉语教材《新实用汉语课本》,并且进行了必要的改良,提升教材实用性。

关键词：汉语教学本土化约旦汉语教材

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