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Neutral Pion Electromagnetic Form Factor as a Bound System of 3 + 1 Dimensional QCD

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Journal of Modern Physics 2024年第7期15卷 1036-1044页

作者： teruo Kurai 1-19-18-503 Unoki Ohta-ku Tokyo Japan

We investigate a neutral pion electromagnetic form factor in momentum space and obtain Gaussian-like function for it. The characteristic form of our neutral pion electromagnetic form factor is consistent with the resu... 详细信息

关键词： Neutral Pion Electromagnetic Form Factor Gaussian-Like Function

Bicarbonate Attenuates Irinotecan-Induced Cytotoxicity through Regulation of Both Extracellular and Intracellular <i>pHs</i>in Intestine Cell Line

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Journal of Cancer Therapy 2013年第5期4卷 944-952页

作者： teruo miyazaki Tadashi Ikegami Yoshiaki Nagai Amy Nguyen Yasushi Matsuzaki Kunihiko Kobayashi Susan Ceryak Department of Biochemistry and Molecular Biology The George Washington University Washington DC USA Department of Internal Medicine Division of Gastroenterology and Hepatology Tokyo Medical University Ibaraki Medical Center Ami Ibaraki Japan Department of Pharmacology The George Washington University Washington DC USA Department of Respiratory Medicine Saitama International Medical Center Saitama Medical University Hidaka Saitama Japan Joint Research Center Tokyo Medical University Ibaraki Medical Center Ami Ibaraki Japan

The anti-cancer therapy of irinotecan (CPT-11) is often limited due to severe late-onset diarrhea. Because the higher toxic form of CPT-11/its active metabolite (SN-38) is produced at acidification, the usefulness of oral sodium bicarbonate treatment against the CPT-11/SN-38-induced intestinal injuries and diarrhea has been confirmed. However, the roles of bicarbonate have been suggested to affect not only intestinal pH environment but also intracellular pH and CPT-11/SN-38 dynamics. The present study proposed to clarify the hypothesis in CPT-11/SN-38-exposed colon cell line in various pH conditions adjusted by bicarbonate. HT29 cell pre-exposed to ~1.0 μM SN-38 lactone or carboxylate forms was incubated at different pH adjusted by either bicarbonate or HCl/NaOH. The degrees of SN-38-induced cell injury depended on the higher proportion of the toxic form (lactone) of SN-38 rather than mere pH condition of medium. Apoptosis and cell injury induced by SN-38 were significantly inhibited by bicarbonate in a dose-dependent manner. Intercellular pH acidification induced by SN-38 was significantly prevented by 30 mM bicarbonate. Cell cytotoxicity of SN-38 depended on not only extracellular but also intracellular pH that converts the SN-38 form, while the intracellular acidification was prevented by bicarbonate. The multiple regulations of bicarbonate on both exracellular and intracellular pH would be essential mechanism against intestinal cell injury by CPT-11/SN-38.

关键词： Bicarbonate SN-38 CPT-11 pHi Anti-Cancer Drug Intestine

PEO coating on Mg-Ag alloy:The incorporation and release of Ag species

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镁合金学报(英文) 2023年第6期11卷 2182-2195页

作者： Xinxin Zhang Yupeng Zhang You Lv Zehua Dong Lei Yang Erlin Zhang teruo Hashimoto Xiaorong Zhou Key Laboratory of Material Chemistry for Energy Conversion and Storage Ministry of EducationHubei Key Laboratory of Material Chemistry and Service FailureSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan 430074China Hubei Engineering Research Centre for Biomaterials and Medical Protective Materials Huazhong University of Science and TechnologyWuhan 430074China Key Laboratory for Anisotropy and Texture of Materials Education Ministry of ChinaSchool of Materials Science and EngineeringNortheastern UniversityShenyang 110819China Corrosion and Protection Centre Department of MaterialsThe University of ManchesterManchester M139PLUnited Kingdom

In the present study,the distribution of Ag in the coating formed on Mg-Ag alloy by plasma electrolytic oxidation(PEO)and its ionic release kinetics when exposed to a 0.9 wt.%Na Cl solution at 37℃have been *** metallic Ag and Ag oxide particles with~5 to~40 nm in diameters were observed in the PEO ***,an Ag-enriched layer of~20 nm in thickness at the substrate/coating interface was also *** PEO coating on the Mg-Ag alloy not only increases its corrosion resistance with the corrosion current density decreasing by up to 3 orders of magnitude from 8.04×10^(-3)to 4.03×10^(-6)A/cm^(2),but also controls the release of Ag+to the level that is sufficient for anti-infective efficacy without causing cytotoxicity to mammal cells.

关键词： Mg-Ag alloy Plasma electrolytic oxidation Ag distribution Ag release Corrosion resistance

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A New Electron Charge Distribution Function of Electron

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Journal of Modern Physics 2023年第2期14卷 111-126页

作者： teruo Kurai Unoki Ota-ku Tokyo Japan

Here we derive a new charge distribution function for an electron by using as an equation of motion a segment of charge whose self energy interaction is due to electric field potential. Our method is based on the consideration that a charged distribution function should be represented as an eigenfunction of electron mass energy. We compare our electron charge distribution function to that of Weinberg’s η(r) and our charged electron radius to that obtained by Kim.

关键词： Charge Distribution Function Electron

Effects of dissolved organic matter on the growth and pigments synthesis of Spirulina platensis (Arthrospira)

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Progress in Natural Science:Materials International 2006年第1期16卷 50-54页

作者： WATANABE teruo China Hainan DIC Microalgae Co. Ltd. Haikou International Commercial Centre 38 Haikou 570102

Excessive accumulation of dissolved organic matter (DOM) in the culture ponds of Spirulina platensis is usually considered to be one of the potential factors affecting the production of S. platensis, however, we are not quite aware of effects of DOM on the growth and pigments synthesis of S. platensis. In the present study, S. platensis was grown in batch or semi-continuous cultures using the filtrate in the culture ponds that had not been renewed for years. It was found that disssolved organic carbon up to 60 mg/L did not bring about an inhibitory effect on the growth of S. platensis, but increased the contents of chlorophyll a and phycocyanin instead. However, further accumulation of dissolved organic matter could decrease the content of chlorophyll a .

关键词： Chl a dissolved organic matter PC specific growth rate Spirulina platensis (Arthrospira).

Effects of solar ultraviolet radiation on the photochemical efficiency, photosynthetic pigments and biomass production of Spirulina platensis

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Progress in Natural Science:Materials International 2005年第5期15卷 477-480页

作者： teruo WATANABE China Haikou 570102 Haikou International Commercial Centre 38 Hainan DIC Microalgae Co. Ltd.

Effects of solar ultraviolet radiation (UVR) on Spirulina platensis were studied by investigating its photochemical efficiency, photosynthetic pigments and biomass production while exposed to full spectrum solar radiation or depleted of UVR for understanding how and to what extent UVR influences its photosynthetic physiology and production. It was found that UVR brought about an extra inhibition of photochemical efficiency by 26%—30%. The greatest inhibition of photochemical efficiency in S. platensis was observed at noontime, and then recovered to some extent in late afternoon no matter which treatment they were exposed to. The contents of chlorophyll a, phycocyanin and carotenoids increased during initial stage of the exposure, but decreased with elongated exposure. UVR decreased the biomass yield by about 6%. It indicated that filtering out UVR of solar radiation would raise the productivity of S. platensis, which is an important factor that should be considered in the production.

关键词： ultraviolet radiation Spirulina platensis photochemical efficiency biomass production pigments.

Surface properties of nitrogen-ion-implanted TiNi shape memory alloy

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Journal of University of Science and Technology Beijing 2006年第2期13卷 154-157页

作者： Chongyan Leng teruo Asaoka Rong Zhou School of Materials and Metallurgical Engineering Kunming University of Science and Technology Kunming 650093 China Department of Intelligent and Mechanical Engineering Tokyo Denki University Hatoyama Hiki-Gun Saitama 350-0394 Japan School of Mechanical Engineering Kunming University of Science and Technology Kunming 650093 China

X-ray diffraction （XRD）, auger electron spectroscopy （AES）, and X-ray photoelectron spectroscopy （XPS） were used to characterize the surface properties of the N^ ＋-ion-implanted TiNi alloy. There is a high nitrogen content region at the outermost surface of the N^＋-ion-implanted TiNi alloy. The detected nitrogen exists mainly in the form of TiN. Small amounts of Ti305 and TiO2 also exist on the surface of the N^＋-ion-implanted TiNi sample. The modified layer of the N^＋-ion-implanted sample can work as an obstacle layer of the nickel＇s dissolution, which obstructs Ni dissolving from the TiNi surface effectively.

关键词： shape memory alloys TiNi surface properties

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Numerical study on 3D effect and practical design in shield tunneling

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Underground Space 2019年第3期4卷 201-209页

作者： Hossain Md.Shahin teruo Nakai Tetsuo Okuno Islamic University of Technology GazipurBangladesh Geo-Research Institute Japan Nagoya Institute of Technology NagoyaJapan Shimizu Corporation TokyoJapan

In practice,different design methods are used in solving geotechnical problems depending on the type of issue such as the tunneling,braced excavation,or bearing capacity of a foundation,that is,the basic mechanism of the design method differs depending on the problems even for the same ground.A numerical analysis using the finite element method has recently become familiar owing to an improved computing performance;however,it is not widely used in the design of geotechnical problems including tunnel excavation owing to the reliability of the constitutive model of the ground *** a constitutive model of soils can properly express the properties of the ground material,a numerical analysis will play a vital role in solving the geotechnical *** this paper,the current state of a numerical analysis and its applicability in tunnel design are ***,the simulation of the ground behavior during tunnel excavation is carried out using sandy and clay ground parameters for shallow and deep tunnel *** paper is mainly focused on the effects of tunnel excavation under three-dimensional(3D)conditions,as well as the current design ***-linear 2D and 3D finite element analyses have been conducted,in which the elastoplastic sub-loading tij model has been used as a constitutive model of the *** performance and acceptability of the constitutive model have already been proven to reproduce the results of various model tests on different geotechnical problems such as the tunneling,braced excavation,and bearing capacity of a foundation,as well as the measured field *** was found that a 2D finite element analysis where the rate of stress release is considered,can be used for the prediction of the ground deformation and surface settlement;however,it does not provide rational information in the prediction of tunnel lining forces such as the stress,bending moment,and axial force,which emphasize the necessity of a 3D analysis with a proper cons

关键词： Shield tunneling Finite element analysis 3D effect

Recent development of temperature-responsive surfaces and their application for cell sheet engineering

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Regenerative Biomaterials 2014年第1期1卷 91-102页

作者： Zhonglan Tang teruo Okano Institute of Advanced Biomedical Engineering and Science TWInsTokyo Women’s Medical University8-1 Kawada-choShinjuku-kuTokyo 162-8666Japan

Cell sheet engineering,which fabricates sheet-like tissues without biodegradable scaffolds,has been proposed as a novel approach for tissue *** have been cultured and proliferate to confluence on a temperature-responsive cell culture surface at 37℃.By decreasing temperature to 20℃,an intact cell sheet can be harvested from the culture surface without enzymatic *** new approach enables cells to keep their cell–cell junction,cell surface proteins and extracellular ***,recovered cell sheet can be easily not only transplanted to host tissue,but also constructed a three-dimensional(3D)tissue by layering cell ***,cell sheet manipulation technology and bioreactor have been combined with the cell sheet technology to fabricate a complex and functional 3D tissue in *** far,cell sheet technology has been applied in regenerative medicine for several tissues,and a number of clinical studies have been *** this review,recent advances in the preparation of temperature-responsive cell culture surface,the fabrication of organ-like tissue and the clinical application of cell sheet engineering are summarized and discussed.

关键词： poly(N-isoproplyacrylamide) temperature-responsive cell culture surface cell sheet cell sheet engineering