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Segment.boundaries of t.e adult.rat.epididymis limit.int.rst.t.al signaling by pot.nt.al paracrine fact.rs and segment. lose different.al gene expression aft.r efferent.duct.ligat.on

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Asian Journal of Andrology 2007年第4期9卷 565-573页

作者： terry t. tumer Daniel S. Johnst.n Scot. A. Jelinsky Jose L. t.msig Joshua N. Finger Depart.ent.of Urology University of Virginia Health Science System Charlottesville VA 22908 US Cell Biology University of Virginia Health Science System Charlottesville VA 22908 US Cont.acept.on Women＇s Health and Musculoskeletal Biology Wyeth Research Collegeville PA 19426 USA Biological t.chnologies Molecular Profiling and Biomarker Discovery Wyeth Research Cambridge MA 02140 USA

t.e epididymis is divided int. caput. corpus and cauda regions, organized int. int.aregional segment. separat.d by connect.ve t.ssue sept. （Ct.）. In t.e adult.rat.and mouse t.ese segment. are highly different.at.d. Regulat.on of t.ese segment. is by endocrine, lumicrine and paracrine fact.rs, t.e relat.ve import.nce of which remains under invest.gat.on. Here, t.e abilit. of t.e Ct. t. limit.signaling in t.e int.rst.t.al compart.ent.is reviewed as is t.e effect.of 15 days of unilat.ral efferent.duct.ligat.on （EDL） on ipsilat.ral segment.l t.anscript.onal profiles. Int.r-segment.l microperifusions of epidermal growt. fact.r （EGF）, vascular endot.elial growt. fact.r （VEGFA） and fibroblast.growt. fact.r 2 （FGF2） increased phosphorylat.on of mit.gen act.vat.d prot.in kinase （MAPK） in segment. 1 and 2 of t.e rat.epididymis and t.e effect. of all fact.rs were limit.d by t.e Ct. separat.ng t.e segment.. Microan＇ay analysis of segment.l gene expression det.rmined t.e effect.of 15 days of unilat.ral EDL on t.e t.anscript.me-wide gene expression of rat.segment. 1-4. Over 11 000 genes were expressed in each of t.e four segment. and over 2 000 t.anscript. in segment.1 responded t. deprivat.on of t.st.cular lumicrine fact.rs. Segment. 1 and 2 of cont.ol t.ssues were t.e most.t.anscript.onally different.and EDL had it. great.st.effect. t.ere. In t.e absence of lumicrine fact.rs, all four segment. regressed t. a t.anscript.onally undifferent.at.d st.t., consist.nt.wit. t.e less different.at.d hist.logy. Deprivat.on of lumicrine fact.rs could st.mulat. an individual gene＇s expression in some segment. yet.suppress it.in ot.ers. Such result. reveal a higher complexit. of t.e regulat.on of rat.epididymal segment. t.an t.at.is generally appreciat.d. （Asian J Androl 2007 July; 9： 565-573）

关键词： efferent.duct.ligat.on dedifferent.at.on proximal epididymis

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Zinc deficiency in t.e pediat.ic age group is common but.underevaluat.d

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World Journal of Pediat.ics 2017年第4期13卷 360-366页

作者： Dogus Vuralli Leyla tumer Alev Hasanoglu Depart.ent.of Pediat.ics Gazi University Faculty of MedicineAnkaraTurkey Depart.ent.of Pediat.ic Met.bolism and Nut.it.on Gazi University Faculty of MedicineAnkaraTurkey

Background:Subclinical micronut.ient.deficiencies have been gradually becoming more import.nt.as a public healt. problem and drawing at.ent.on of t.e healt. *** it.has been known t.at.det.ct.ng and t.eat.ng people having deficiency sympt.ms alone is no longer *** is import.nt.t. det.ct.and prevent.any deficiency before it.displays clinical *** deficiency is one of t.e most.widespread micronut.ient.*** t.is st.dy,we aimed t. evaluat. t.e zinc st.t.s and t.e associat.d fact.rs in healt.y school-age ***:t.e st.dy was carried out.in schools in Alt.ndag,t.e dist.ict.of Ankara.A t.t.l of 1063 healt.y children,585 girls and 478 boys,aged 5-16 years were included in t.e *** zinc,high-sensit.vit. C-react.ve prot.in levels and whit. blood cell count.were measured.A serum zinc level 10 years of age t.e cut.ffs for serum zinc concent.at.on were set.at.66 μg/dL for females and 70 μg/dL for males.A quest.onnaire was developed t. collect.socioeconomic and demographic informat.on of t.e ***:t.e prevalence of subclinical zinc deficiency in children at.ending t.e st.dy was det.ct.d t. be 27.8%.t.is high rat.o showed zinc deficiency was an import.nt.healt. problem in t.e Alt.ndag dist.ict.of Ankara,***:Evaluat.ng t.e indicat.rs of zinc deficiency such as serum zinc concent.at.on,diet.ry zinc int.ke and st.nt.ng prevalence,t.is st.dy is t.e most.comprehensive epidemiological st.dy performed in children in *** st.dy reveals t.e high prevalence of subclinical zinc deficiency and indicat.s t.at.zinc deficiency is a public healt. concern for t.e st.dy populat.on.

关键词： nut.it.onal deficiency subclinical zinc

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Pect.ral muscular t.it.hing： a rare manifest.t.on of spont.neous t.iddler syndrome

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Journal of Geriat.ic Cardiology 2017年第8期14卷 532-533页

作者： Serdar Bozyel t.lga Aksu tumer Erdem Guler Kaznn Serhan Ozcan Mujdat.Akt.s Derince t.aining and Research Hospit.l Department of Cardiology Kocaeli Turkey Eregli St.t. Hospit.l Department of Cardiology Zonguldak Turkey

t.e t.iddler syndrome is maker malfunct.on, in which vice in it. pocket.result. in an uncommon cause of pace-t.ist.ng or rot.t.ng of t.e delead ret.act.on or coiling and subsequent.malfunct.on of an implant.d devices such as a pacemaker, an implant.ble cardiovert.r-defibrillat.r （ICD）, cardiac resynchronizat.on t.erapy （CRt..

关键词： Pacemaker t.iddler

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Quant.t.t.ve Analysis of Paleoat.ospheric CO2 Level Based on St.mat.l Charact.rs of Fossil Ginkgo from Jurassic t. Cret.ceous in China

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Act. Geologica Sinica(English Edit.on) 2007年第6期81卷 931-939页

作者： SUN Bainian XIAO Liang XIE Sanping DENG Shenghui WANG Yongdong JIA Hui Susan tumer Key Laborat.ry of West.rn China＇s Environment.l Syst.ms of t.e Minist.y of Educat.on Lanzhou University Lanzhou 730000 China St.t. Key Laborat.ry of Palaeobiology and St.at.graphy Nanjing Institute of Geology and Palaeontology Chinese Academy of Sciences Nanjing 210008 China Research Inst.t.t. of Pet.oleum Explorat.on and Development Beijing 100083 China Queensland Museum South Brisbane Queensland 4101 Australia

A bet.er t.eoret.cal and pract.cal underst.nding of t.e linkage bet.een paleo-CO2 and climat. during geological hist.ry is import.nt.t. enhance t.e sust.inable development.of modern human societ.. Development.in plant.physiology since t.e 1980s has led t. t.e realizat.on t.at.fossil plant. can serve as a proxy for paleoat.osphere and paleobiosphere. As a relict.gymnosperm wit. evolut.onary st.sis, Ginkgo is well suit.d for paleoenvironment.l reconst.uct.on. t.is paper analyzes fossil Ginkgo species from int.grat.d st.at. in t.e nort. of China using anat.mic dat. of plant.physiology. Using st.mat.l paramet.rs, a t.end for t.e paleo-CO2 level during t.e Early-Middle Jurassic and t.e Early Cret.ceous was obt.ined, which is consist.nt.wit. t.e est.mat.s by GEOCARB. t.e t.end is also similar t. t.at.of Mean Global Surface t.mperat.re in geological t.me. Compared wit. t.ree ot.er at.ospheric CO2 concent.at.on paramet.rs, t.e t.end of paleo-CO2 level based on t.e st.mat.l paramet.r of t.e fossil Ginkgo specimens from t.ree cont.guous st.at. is more exact.

关键词： Jurassic Cret.ceous fossil Ginkgo st.mat.l paramet.r paleoat.ospheric CO2

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人体小腿受冲击载荷作用时的生物动力响应

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生物医学工程学杂志 2000年第2期17卷 155-158页

作者：王西十白瑞蒲 S.t.rgut.tumer 河北大学数学系保定071002 Depart.ent.of Mechanical Engineering Middle East Technical University

建立了人体下肢大腿固定而小腿在矢状面内运动时的生物动力模型，并对这类数学模型的求解，发展了一种有效且易于使用的解法技术。作为应用，计算了当小腿在胫骨质量中心遭受冲击载荷时，由此而引起的膝关节咬合接触力、膝关节处的4个... 详细信息

建立了人体下肢大腿固定而小腿在矢状面内运动时的生物动力模型，并对这类数学模型的求解，发展了一种有效且易于使用的解法技术。作为应用，计算了当小腿在胫骨质量中心遭受冲击载荷时，由此而引起的膝关节咬合接触力、膝关节处的4个主要韧带所承受的张力以及膝关节股骨与胫骨咬合时的接触点的位置、小腿的前后屈伸位移和运动轨迹等。

关键词：人体小腿冲击载荷生物动力响应

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ARL成员馆实时咨询开展情况调查

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图书馆理论与实践 2004年第1期 86-88页

作者： Jana Ronan Carol tumer 关志英清华大学图书馆北京100084

通过发放调查问卷和访问各图书馆的主页 ,美国研究图书馆协会对其所属的 12 4家图书馆的实时咨询 (Chat.eference)开展情况做了深入细致的调查研究。许多经验值得我国正在开展和准备开展实时咨询服务的图书馆参考借鉴。

关键词： ARL “美国研究图书馆协会” 实时咨询虚拟参考咨询数字参考咨询馆员结构用户研究

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一个解剖基人体下肢的生物动力模型──第三部分:肌肉效应

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力学与实践 2000年第3期22卷 44-48页

作者：王西十白瑞蒲 S.t.rgut.tumer Nuri Akkas Ugur Gunel 河北大学数学系保定071002 Dept.of Mechanical Engineering Middle East Technical Universityankaraturkey06531 Dept.of Engineering Science Middle East Technical Universityankaraturkey06531 Ankara Hospit.l ankaraturkey06532

本文将人体下肢的肌肉根据其解剖特征，分为5个肌群，并在由本文第一部分所建立的基本的解剖基模型的基础上，计入其对人体下肢动力运动的效应．本文所建立的5个肌群，则主要代表着膝关节处的运动和稳定肌．最后，作为应用，研究了一个... 详细信息

本文将人体下肢的肌肉根据其解剖特征，分为5个肌群，并在由本文第一部分所建立的基本的解剖基模型的基础上，计入其对人体下肢动力运动的效应．本文所建立的5个肌群，则主要代表着膝关节处的运动和稳定肌．最后，作为应用，研究了一个文献中的特例．

关键词：人体下肢肌群肌内效应生物动力模型

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