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Systematic evaluation and Meta-analysis of the efficacy of Xiaochaihu Decoction in the treatment of chronic superficial gastritis

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Drug Combination Therapy 2019年第4期1卷 224-236页

作者： Shi-Jun Li teng huang Xiao-Li Ma College of Traditional Chinese Medicine Hebei UniversityBaodingChina071000

Objective:To compare the effectiveness of Xiaochaihu Decoction(XCHD)or the modified XCHD combined with western medicine in the treatment of superficial ***:We collected the studies about XCHD or the modified XCHD combined with western medicine for superficial gastritis in China Biology Medicine(CBM)Database(2010-2018),China National Knowledge Infrastructure(CNKI)Database(2010-2018),VIP Database(2010-2018),Wanfang Database(2010-2018)and the Back Issues Database of Hebei *** randomized controlled trials(RCTs)were included in this *** literatures were independently extracted by two researchers and the Cochrane Review Handbook(version 5.1.0)was applied to assess the quality of included *** analysis was performed with RevMan(version 5.3).Results:A total of 8 RCTs,including 732 cases,were included ***-analysis results showed that compared with the western medicine treatment group,XCHD or the modified XCHD combined with western medicine could improve the total effective rate[OR=4.67,95%CI(2.90,7.55),P<0.00001],physiological function[MD=10,95%CI(8.78,11.23),P<0.00001],role physical[MD=13.85,95%CI(11.19,16.51),P<0.00001],physical pain[MD=11.64,95%CI(9.05,14.23),P<0.00001],general health[MD=11.20,95%CI(9.52,12.88),P<0.00001],vitality[MD=13.46,95%CI(12.30,14.62),P<0.00001],social function[MD=19.20,95%CI(17.32,21.09),P<0.00001],affection function[MD=30.3,95%CI(28.99,31.62),P<0.00001],mental health[MD=9.80,95%CI(8.44,11.16),P<0.00001].Conclusion:XCHD or the modified XCHD combined with western medicine in the treatment of superficial gastritis has good performance in clinical efficacy and the improvement of quality of ***,with several methodology problems existing in the included RCTs,the effectiveness of XCHD or the modified XCHD is still need more high-quality randomized,double-blind,placebo-controlled trials to further confirmed.

关键词： Modified Xiaochaihu Decoction Chronic superficial gastritis Randomized controlled trials System evaluation

QCFVA:A tool for qualitative classification of reactions based on flux variability analysis

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QCFVA:A tool for qualitative classification of reactions bas...

Recent progress in chiral zeolites: Structure, synthesis,characterization and applications

中国生物工程学会第六次全国会员代表大会暨第九届学术年会

作者：李培顺 Hongwu Ma teng huang 中国科学院天津工业生物技术研究所 Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences

Background:Flux variability analysis is usually used to determine the minimum and maximum flux values that the reactions in the metabolic network can carry under various simulation *** several approaches have been proposed for that purpose,they are computationally too inaccurate to qualitatively classify reactions in genome-scale metabolic network models(GSMs).Therefore,developing preciser methods to analysize robustness of metabolic network models is ***:We develop a new tool for qualitative classification of reactions base on flux variability analysis called QCFVA,which overcomes the problem of calculation accuracy of the exiting *** implementation of QCFVA was mainly divided into three steps:Firstly,the target reaction,such as biomass growth,was set as the objective function and FBA was used to maximize the flux of the target reaction(mentioned as the first simulation);Secondly,the flux of target reaction was set to the maximum value calculated in the first simulation;Finally,all the n reactions were considered as objective function in turn and FBA was again used to calculate the maximum and minimum fluxes of each reaction in GSMs,***:We show that the improved implementation of QCFVA makes classification of reactions,calculation of the bounds on the reaction fluxes and flux balance impact degree(FBID) of single reaction deletion more exactly,greatly expanding the application of flux variability analysis in systems biology from prediction of genetic manipulation targets in genome scale to integration of high-throughput biological data to construct multi-scale whole-cell network model.

关键词： flux variability analysis genome-scale metabolic network reaction classification

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Chinese Chemical Letters 2024年第12期35卷 33-42页

作者： teng-Yu huang Junliang Sun De-Xian Wang Qi-Qiang Wang Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Molecular Recognition and FunctionInstitute of ChemistryChinese Academy of SciencesBeijing 100190China College of Chemistry and Molecular Engineering Beijing National Laboratory for Molecular SciencesPeking UniversityBeijing 100871China University of Chinese Academy of Sciences Beijing 100049China

Zeolites are crystalline porous materials that are used in the chemical industry for adsorption, separation and catalytic reactions. Chiral zeolites have shown promise in enantioselective adsorption and catalytic organic reactions, attracting significant research interest. Recent advances have been made in the rational design, computational prediction and hydrothermal synthesis of using chiral organic structure-directing agents. Additionally, newly developed electron microscopic techniques have been utilized to analyze the structure and determine absolute configuration. The following review aims to provide an overview of the development history of chiral zeolites, examine several prominent chiral zeolite structures discovered so far, discuss the recent progress in characterization methods and explore their potential applications.

关键词： Chiral zeolite Chirality Organic structure-directing agent Absolute configuration Electron microscopy Enantioselective catalysis

Orientation dependence in high harmonics of ZnO with polarization corrections to counteract the birefringent effect

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Chinese Physics B 2021年第7期30卷 269-273页

作者： Yin-Fu Zhang teng-Fei huang Jia-Peng Li Ke Yang Liang Li Xiao-Song Zhu Peng-Fei Lan Pei-Xiang Lu School of Physics and Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory of Optical Information and Pattern Recognition Wuhan Institute of TechnologyWuhan 430205China CAS Center for Excellence in Ultraintense Laser Science Shanghai 201800China

We investigate the influence of the birefringence on the high-order harmonics in an a-cut Zn O crystal with midinfrared laser *** high harmonics exhibit strong dependence on the alignment of the crystal with respect to the laser *** introduce the Jones calculus to counteract the birefringent effect and obtain the harmonics with polarization corrections in Zn *** show that the birefringent effect plays an important role in the orientation dependence of HHG.

关键词： high-order harmonics birefringent effect Jones calculus

Diagnosis and treatment of psoriatic arthritis with concealed rash: a case report

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TMR Clinical Research 2019年第2期2卷 57-63页

作者： teng huang Shaopeng Du Xiaojing Liu Zhenhua Liu Bin Hao Hebei university Baoding Hebei China Chinese people's liberation Army 252 Hosptital Baoding Hebei China

Psoriatic arthritis is a kind of arthritis associated with psoriasis. The clinical manifestations of psoriatic arthritis with arthritis as the first symptom are often similar to ankylosing spondylitis and rheumatoid arthritis. Thus differential diagnosis should be made in clinical practice so as to improve the therapeutic effect. Psoriatic arthritis skin lesions are usually papules or plaques, with scales on the surface and punctate hemorrhage on the basement. About 10% of patients with psoriatic arthritis have skin rash after the onset of arthritis. In order to provide a reference for clinicians, our study the analyzed the clinical diagnosis of psoriatic arthritis in combination with a case of psoriatic arthritis with concealed skin rash and related literatures.

关键词： psoriatic arthritis concealed rash clinical diagnosis

LipoCol Forte capsules reduce the risk of liver cancer:A propensity score-matched,nationwide,population-based cohort study

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World Journal of Gastrointestinal Oncology 2023年第5期15卷 828-842页

作者： Hsiang-Chun Lai Hung-Jen Lin Ying-Hsiu Shih Jen-Wei Chou Kuan-Wen Lin Long-Bin Jeng Sheng-teng huang Graduate Institute of Chinese Medicine School of Chinese MedicineCollege of Chinese MedicineChina Medical UniversityTaichung 40447Taiwan School of Post-Baccalaureate Chinese Medicine College of Chinese MedicineChina Medical UniversityTaichung 40402Taiwan Management Office for Health Data China Medical University HospitalTaichung 40447Taiwan Department of Internal Medicine China Medical University HospitalTaichung 40447Taiwan Department of Surgery China Medical University HospitalTaichung 40447Taiwan Organ Transplantation Center China Medical University HospitalTaichung 40447Taiwan Department of Chinese Medicine China Medical University HospitalTaichung 40447Taiwan Cancer Research Center for Traditional Chinese Medicine Department of Medical ResearchChina Medical University HospitalTaichung 40447Taiwan An-Nan Hospital China Medical UniversityTainan 709204Taiwan School of Chinese Medicine China Medical UniversityTaichung 40447Taiwan

BACKGROUND Liver cancer is among the top five most common cancers globally. Lipid-lowering drugs such as statins can lower the risk of liver cancer, but may also cause liver damage. LipoCol Forte capsules(LFC), a red yeast rice product, have demonstrated significant antihypercholesterolemic effects and a good safety profile in clinical *** To evaluate whether LFC lowers the risk of liver cancer in adults in this propensity score-matched, nationwide, population-based cohort *** We used data from Taiwan’s National Health Insurance Research Database, which includes electronic medical records for up to 99.99% of Taiwan’s population. LFC users and LFC non-users were matched 1:1 by propensity scores between January 2010 and December 2017. All had followup data for at least 1 year. Statistical analyses compared demographic distributions including sex, age, comorbidities, and prescribed medications. Cox regression analyses estimated adjusted hazard ratios(aHRs) after adjusting for potential *** We enrolled 33231 LFC users and 33231 non-LFC users(controls). No significant differences between the study cohorts were identified regarding comorbidities and medications [standardized mean difference(SMD) < 0.05]. At follow-up, the overall incidence of liver cancer was significantly lower in the LFC cohort compared with controls [aHR 0.91;95% confidence interval(CI): 0.86-0.95;P < 0.001]. The risk of liver cancer was significantly reduced in both females(aHR 0.87;95%CI: 0.8-0.94;P < 0.001) and males(aHR 0.93;95%CI: 0.87-0.98;P < 0.01) in the LFC cohort compared with their counterparts in the non-LFC cohort. The antitumor protective effects applied to patients with comorbidities(including hypertension, ischemic stroke, diabetes mellitus, hyperlipidemia, hepatitis B infection and hepatitis C infection). Those using LFC for more than 84 drug days had a 0.64-fold lower risk of liver cancer compared with controls(P < 0.001). Compared with controls, the

关键词： LipoCol Forte capsules Hyperlipidemia Liver cancer Hepatocellular carcinoma Retrospective cohort study Taiwan National Health Insurance Research Database

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采用真空预压法处理公路软基滑塌的试验研究

土木工程学报 2009年第6期42卷 133-139页

作者：黄腾广东省航盛建设集团有限公司广东广州511442

以采用真空预压处理高速公路软基滑坡的工程实例为基础,通过原型观测和室内外土工试验,研究真空预压处理软基滑坡的施工工艺和处理效果,为了缩短施工时间,结合高速公路软基滑坡处治工程的特点,对铺膜方法、堆载时机等真空预压施工工艺... 详细信息

以采用真空预压处理高速公路软基滑坡的工程实例为基础,通过原型观测和室内外土工试验,研究真空预压处理软基滑坡的施工工艺和处理效果,为了缩短施工时间,结合高速公路软基滑坡处治工程的特点,对铺膜方法、堆载时机等真空预压施工工艺进行改进。工程实践表明,改进后的真空预压法能在较短的时间内成功处理高速公路软基滑坡事故。滑坡处治过程中的侧向位移监测数据较清晰地反映了软基旧滑动带的分布范围和扩展过程,对此进行定量分析。侧向位移、孔隙水压力及地表沉降等监测数据均表明:真空预压可以有效控制旧滑动带的扩展和分布范围,进而控制软基的整体稳定性。室内外土工试验和工后沉降监测表明:在真空预压和堆载共同作用下,虽然经过前期预压的已滑软基土体的含水量降低较小,但是二者联合却能较明显地改善已滑软基土体的压缩性,进而降低工后沉降。真空预压是一种能快速处理软基滑坡的方法。

关键词：软基滑坡真空预压

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专利补贴与年末效应

财贸经济 2024年第8期45卷 154-168页

作者：李锴黄腾厦门大学邹至庄经济研究院 361005 厦门大学经济学院和王亚南经济研究院 361005

与以往考察跨年度专利数量和质量变化的研究不同,本文探讨了专利补贴政策对同一年度内不同时间段专利申请数量和质量的影响,为解释中国创新质量与数量的不均衡发展提供了新视角。首先,本文展示了年末申请的专利数量占比最高、质量最差... 详细信息

与以往考察跨年度专利数量和质量变化的研究不同,本文探讨了专利补贴政策对同一年度内不同时间段专利申请数量和质量的影响,为解释中国创新质量与数量的不均衡发展提供了新视角。首先,本文展示了年末申请的专利数量占比最高、质量最差的特征,并通过理论模型刻画了补贴政策对这一现象的影响。其次,本文基于2001一2014年300多万条发明专利申请数据,实证检验了中国专利申请存在年末效应。进一步,本文以各省份首次出台专利补贴政策作为准自然实验,验证了财政补贴将强化年末数量上升效应、引致年末质量下降效应的理论假说。最后,研究结论在不同申请主体、不同质量衡量方法、不同参照时间段和去除部分地区或年份样本等一系列稳健性检验后,仍然成立。本文为进一步优化财政补贴在创新发展中的作用提供了理论与实证支持。

关键词：专利补贴年末效应创新

中国供水行业技术效率及影响因素分析——基于256个城市的SFA测度研究

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城市问题 2020年第5期 4-10页

作者：李凡黄腾深圳大学中国经济特区研究中心北京师范大学经济与资源管理研究院

我国长期面临严峻的水资源形势,提高城市供水效率问题备受关注。基于全国地级及以上城市五年供水数据,运用SFA方法构建投入产出模型,考察水源、技术指标、佣工结构、消费者结构对城市供水行业技术效率的影响,并估计了其技术效率值。实... 详细信息

我国长期面临严峻的水资源形势,提高城市供水效率问题备受关注。基于全国地级及以上城市五年供水数据,运用SFA方法构建投入产出模型,考察水源、技术指标、佣工结构、消费者结构对城市供水行业技术效率的影响,并估计了其技术效率值。实证结果显示:增加资本、专业劳动力、供水电量等生产投入能够显著提高供水量;居民生活用水占比、管网压力合格率与技术效率显著负相关,消费者密度、水资源天然禀赋与技术效率显著正相关;城市供水行业技术效率均值为0. 55,二线城市技术效率最高,均值达0. 6。

关键词：城市供水行业技术效率运营环境随机前沿分析