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Total pancreatectomy for metachronous mixed acinar-ductal carcinoma in a remnant pancreas

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World Journal of Gastroenterology 2014年第33期20卷 11904-11909页

作者： tatsuya Shonaka Mitsuhiro Inagaki Hiromitsu Akabane Naoyuki Yanagida Hiroki Shomura Nobuyuki Yanagawa Kensuke Oikawa Shiro Nakano Division of Surgery Hokkaido PWFAC Asahikawa-Kosei General Hospital Asahikawa 78-8211 Japan Gastroenterology Endoscopic Center Hokkaido PWFAC Asahikawa-Kosei General Hospital Asahi-kawa 78-8211 Japan Department of Pathology Asahikawa Medical University Asahikawa 78-8510 Japan

In October 2009, a 71-year-old female was diagnosed with a cystic tumor in the tail of the pancreas with an irregular dilatation of the main pancreatic duct in the body and tail of the pancreas. A distal pancreatectomy with splenectomy, and partial resection of the duodenum, jejunum and transverse colon was performed. In March 2011, a follow-up computed tomography scan showed a low density mass at the head of the remnant pancreas. We diagnosed it as a recurrence of the tumor and performed a total pancreatectomy for the remnant pancreas. In the histological evaluation of the resected specimen of the distal pancreas, the neoplastic cells formed an acinar and papillary structure that extended into the main pancreatic duct. Mucin5AC, α1-antitrypsin (α-AT) and carcinoembryonic antigen (CEA) were detected in the tumor cells by immunohistochemistry. In the resected head of the pancreas, the tumor was composed of both acinar and ductal elements with a mottled pattern. The proportions of each element were approximately 40% and 60%, respectively. Strongly positive α-AT cells were detected in the acinar element. Some tumor cells were also CEA positive. However, the staining for synaptophysin and chromogranin A was negative in the tumor cells. Ultimately, we diagnosed the tumor as a recurrence of mixed acinar-ductal carcinoma in the remnant pancreas. In conclusion, we report here a rare case of repeated pancreatic resection for multicentric lesions of mixed acinar-ductal carcinoma of the pancreas.

关键词： Mixed acinar-ductal carcinoma Pancreatic cancer Acinar carcinoma Total pancreatectomy

High intensity interval training and molecular adaptive response of skeletal muscle

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Sports Medicine and Health Science 2019年第1期1卷 24-32页

作者： Ferenc Torma Zoltan Gombos Matyas Jokai Masaki Takeda tatsuya Mimura Zsolt Radak Research Center of Molecular Exercise Science University of Physical EducationBudapestHungary Faculty of Health and Sports Science Doshisha UniversityKyotanabeJapan Faculty of Sport and Health Sciences Osaka Sangyo UniversityOsakaJapan

Increased cardiovascular fitness,VO_(2max),is associated with enhanced endurance capacity and a decreased rate of *** intensity interval training(HIIT)is one of the best methods to increase VO_(2max)and endurance capacity for top athletes and for the general public as *** of the high intensity of this type of training,the adaptive response is not restricted to Type I fibers,as found for moderate intensity exercise of long *** with a short exercise duration,HIIT can induce activation of AMPK,PGC-1α,SIRT1 and ROS pathway as well as by the modulation of Ca^(2+)homeostasis,leading to enhanced mitochondrial biogenesis,and *** present review summarizes the current knowledge of the adaptive response of HIIT.

关键词： High intensity interval training Cellular adaptation Molecular pathways Redox signaling Maximal oxygen uptake Mitochondrial biogenesis

Can we go beyond INDCs： Analysis of a future mitigation possibility in China, Japan, EU and the U.S.

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Advances in Climate Change Research 2017年第2期8卷 117-122页

作者： JIANG Ke-Jun Kentaro TAMURA tatsuya HANAOKA Energy Research Institute (ERI) Beijing 100038 China Institute for Global Environmental Strategies (IGES) Hayama 240-0115 Japan National Institute for Environmental Studies (NIES) Tsukuba 305-8506 Japan

The most important achievement in the Paris Agreement is to set up emission reduction target by commitment submitted by each country/ region with the form INDC. However the emission reduction target inside INDCs could not match with the emission pathway for the global to keep a global temperature rise this century well below 2 ℃ and to drive efforts to limit the temperature increase even further to 1.5 ℃ above pre- industrial levels. It is important for countries to do more than their commitment in INDCs, especially in near term. This paper looks at the near term trend for possibilities for further emission reduction compared with INDCs, and found there do have the possibility. It concludes there is space for the four countries/regions to do more than their INDCs submitted to UNFCCC, and see the light towards to a global 2 ℃ target.

关键词： Climate change Mitigation INDC NDC COP21

Performance and stability analysis of SOFC containing thin and dense gadolinium-doped ceria interlayer sintered at low temperature

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Journal of Materiomics 2022年第2期8卷 347-357页

作者： Yige Wang Chuan Jia Zewei Lyu Minfang Han Junwei Wu Zaihong Sun Fumitada Iguchi Keiji Yashiro tatsuya Kawada Department of Energy and Power Engineering Tsinghua UniversityBeijing100084China Department of Materials Science and Engineering Harbin Institute of Technology(Shenzhen)Shenzhen518055China Suzhou Huatsing Jingkun New Energy Technology Co.Ltd Jiangsu215314China Tohoku University Sendai 980-8579Japan

Gadolinium-doped ceria(GDC)interlayers are required to prevent the interfacial reaction between La_(0.6)Sr_(0.4)Co_(0.2)Fe_(0.8)O_(3)(LSCF)cathode and Y_(2)O_(3)-stabilized ZrO 2(YSZ)electrolyte in solid oxide fuel cells(SOFCs).However,it's difficult to prepare a thin and dense GDC interlayer on the sintered half-cell at a low *** this study,the physical vapor deposition(PVD)method was employed to success-fully manufacture dense GDC interlayers with the thickness of 1 m *** influences of GDC sintering temperature(900℃,1000℃ and 1100℃)on cell performance characteristics and degradation behavior were *** cell with GDC interlayer sintered at 1100?C showed the lowest degradation rate during the 216-h *** best stability was attributed to the most effective inhibition of Sr diffusion by the GDC interlayer,which was demonstrated by the almost unchanged Ohmic and polari-zation resistances during the aging stage and the negligible Sr enrichment at YSZ/GDC *** to the conventional screen-printed GDC interlayers(sintered above 1250℃),the GDC inter-layer prepared by the PVD method and sintered at 1100℃ was significantly denser and thinner,showing a promising application prospect due to its benefits for cell stability.

关键词： Solid oxide fuel cell Gadolinium-doped ceria Interlayer Sr diffusion Stability analysis

Multidrug Delivery Systems with Single Formulation——Current status and Future Perspective

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Journal of Biomaterials and Nanobiotechnology 2012年第1期3卷 50-60页

作者： tatsuya Okuda Satoru Kidoaki Division of Biomolecular Chemistry Institute for Materials Chemistry and Engineering Kyushu University Fukuoka Japan.

Development of new way and system for multidrug delivery has recently attracted much attention and became one of major issue in drug delivery research. Although this research field is still immature compared to the single drug delivery system, intensive efforts have recently been devoted by researchers in order to realize more efficient, functional, and safe combination therapy using multiple drugs or agents. In this review article, we outline several targets in terms of application for biochemical modulation together with various concrete attempts of simultaneous and sequential delivery of multiple drugs or agents with single formulation. Finally, we will also summarize the possible contribution of biomaterial sciences and nanobiotechnology for improvement of future multidrug delivery system.

关键词： Multidrug Delivery System Single Formulation Combination Therapy Biochemical Modulation

Homeostasis Lighting Control System Using a Sensor Agent Robot

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Intelligent Control and Automation 2013年第2期4卷 138-153页

作者： tatsuya Akiba Akira Mita Department of System Design Engineering Keio University Yokohama Japan

In this study, “homeostasis”, the function by which living things keep their constancy, was emulated as a lighting control for a building space. The algorithm we developed mimics the mechanisms of the endocrine and immune systems. The endocrine system transmits information entirely, whereas the immune system transmits information with a concentration gradient. A lighting control system using the proposed algorithm was evaluated in a simulation and experiment using a sensor agent robot. In this algorithm, a robot recognizes a person’s behavior and uses it to decide his or her preference as to the illuminance. The results indicate that the algorithm can be used to realize a comfortable lighting control in several situations.

关键词： Homeostasis Lighting Control Sensor Agent Robot Human Tracking

Shrinkage, Strength of High and Ordinary Concrete Incorporating Kosovo and Japanese Fly-ash

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Journal of Environmental Science and Engineering(A) 2016年第9期5卷 444-451页

作者： Anjeza Alaj tatsuya Numao Department of Urban and Civil Engineering Ibaraki University Hitachi 316-8511 Japan

Ordinary and high performance concrete （OC-C 25/30 and HPC C-50/60） made with fly ash has found numerous applications all over the world since 1970. In Kosovo, fly ash as cement substitution in concrete has not been utilized yet despite the large amount that is produced annually and the positive economical-environment aspects of such technique. This hesitance is due to the laek of experience in the concrete engineering field and because of the chemical composition of Kosovo fly ash, which is classified as non-standard high calcium fly ash （KF）. In light of this fact, this study intended to develop further. So, this paper reports the consistency, workability, shrinkage, high and ordinary compressive strength of concrete containing different percentage of non-class high calcium fly ash as Portland cement substitution （first case-Kosovo fly ash KF） comparing results with F class-low caleium fly ash content （second ease-Japanese fly ash JF） which is common used as cement replacement.

关键词： Non-standard fly ash ordinary and high performance concrete compressive strength shrinkage.

A Survey for Exploring Personality Traits of Excessive Online Game Users in Japan

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Computer Technology and Application 2012年第12期3卷 818-825页

作者： tatsuya Nomura Yuma Goto Department of Media Informatics Ryukoku University Otsu Shiga 520-2194 Japan MFK Ltd. Kobe Hyogo 651-1121 Japan

For the aim at exploring differences on personality traits between excessive online game users and non-excessive users in Japan, an online survey was conducted using psychological scales measuring addictive tendencies for online gaming, depressive tendencies, aggression, and self-concealment. The results revealed that excessive online game users having addictive tendencies in Japan had lack of self-esteem as one of depressive tendencies, high aggressive tendencies, and low tendency of self-disclosure, in contrast with non-excessive users. Moreover, it was suggested that these users had a confidence in the society based on contributive behaviors in multi-player groups of online gaming.

关键词： Online gaming addiction personality traits questionnaire survey.

Correction: MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

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Oncology Research 2024年第8期32卷 1369-1370页

作者： HUI SUN MASANORI KAWANO tatsuya IWASAKI ICHIRO ITONAGA YUTA KUBOTA HIROSHI TSUMURA KAZUHIRO TANAKA Department of Orthopaedic Surgery Faculty of MedicineOita UniversityOita879-5503Japan

In the article‘MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1’(Oncology Research,2024,Vol.32,No.3,pp.463−***:10.32604/or.2023.044085),there was an error in the compilation of *** have revised Fig.8D to correct this error.A corrected version of Fig.8 is *** correction does not change any results or conclusions of the *** apologize for any inconvenience caused.

关键词： osteosarcoma correction revised