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Clinical Characteristics of Nystagmus in Albinos Living in Libreville

Open Journal of Ophthalmology 2020年第1期10卷 69-76页

作者： Prudence Ada Assoumou tatiana mba aki Olele Oussavou Emmanuel Mve Mengome Department of Ophthalmology Faculty of Medicine University of Health and Science Libreville Gabon Ophthalmology Department of Agondje University Hospital Center Libreville Gabon

Introduction: Nystagmus is a static ocular disorder characterized by an oscillatory, involuntary and rhythmic movement of eyes. In Libreville, no data on the subject is available. The purpose of this study is to describe clinical characteristics of nystagmus in albinos living in Libreville. Methods: This is a descriptive, cross-sectional study including 43 albinos with oculocutaneous albinism and nystagmus during the period from February 01, 2017 to February 01, 2018. Variables studied were age, sex, visual acuity, objective refraction, characteristics of the nystagmus including morphology, direction, intensity and associated signs such as stiff neck and squint. Results: The mean age was 21.2 ± 17 years with a female-dominated ratio of 0.53. The visual acuity from afar without correction (AVLSC) was less than 3/10 in 88.4% of the cases. The most common ametropia was astigmatism in 51.2% of cases. Nystagmus was present in all albinos. The spring type was found in 69.7% of cases. The direction was horizontal in 67.4% of the cases and rotary in 32.6% of the cases. The intensity was moderate in 55.8% of cases. The blocking position was the primary near vision position in 69.7% of the cases. Nystagmus was associated with a stiff neck in 28% of the cases and strabismus in 48.8% of the cases. Conclusion: The albinos nystagmus living in Libreville is of the spring type, horizontal direction, of moderate intensity and calmed in the primary position in near vision.

关键词： Nystagmus Albinos Libreville

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Ocular Manifestations Encountered in Albinos Living in Libreville: Epidemiological and Clinical Aspects

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Open Journal of Ophthalmology 2019年第4期9卷 203-213页

作者： Prudence Ada Assoumou Andy Viola Dohvoma Steve Mvogo Ebana tatiana mba aki Olele Ossavou Assomo Emmanuel Mve Mengome Come Ebana Mvogo Department of Ophthalmology Faculty of MedicineUniversity of Health and ScienceLibrevilleGabon Ophthalmology Department of Agondje University Hospital Center LibrevilleGabon Faculty of Medicine and Biomedical Sciences University of Yaounde IYaoundeCameroon Omar Bongo Ondimba Army Instructions Hospital LibrevilleGabon

Introduction: Albinism is a rare hereditary genetic disorder, characterized by melanogenesis disorders associated to varying degrees of cutaneous, atrial and visual disorders. In Libreville, no data on the subject is available. Purpose: To describe the ocular manifestations found in albinos living in Libreville. Patients and methods: This was a cross-sectional and descriptive study that took place in Libreville during a year from and that concerned 43 albinos. The inclusion criteria were any albino with oculocutaneous albinism present in Libreville who has agreed to participate in the investigation. The variables studied were age, sex, visual acuity, ametropia, iris color, iris transillumination, strabismus, nystagmus, torticollis, amblyopia, optic disc, photophobia, foveal hypoplasia and retinal hypopigmentation. Data was collected and analyzed using Epi infoTM 7.***.0.1 CDC and?IBM®?SPSS®?V21 Statistic software. Results: The mean age was 21.2 ± 17 years with a (F/M) ratio of 0.53. Visual acuity by far without correction (AVLCSC) < 3/10 was found in 88.4% of cases. Astigmatism, two-tone iris and torticollis were found respectively in 52.7%, 51% and 26% of cases. Retinal hypopigmentation and foveal hypoplasia were noted in 65.1% and 86% of cases. Divergent strabismus was noted in 71.4% and small and pale papilla in 95.1% of cases. Photophobia, iris transillumination, nystagmus and amblyopia were noted in 100% of cases. Conclusion: The ocular manifestations encountered in our series are similar to those described in literatures.

关键词： Albinism Nystagmus Strabismus Amblyopia Torticollis Photophobia Li-breville

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