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Jo.rnal o. Spo.t and Health Science 2024年第6期13卷 756-758页

作者： Raphael H.o.Araujo.Andre o.Werneck Gilmar M.de Jesus Danilo.R.P.Silva Graduatio. Pro.ram in Health Sciences Londrina State UniversityLondrina 86057-970Brazil Scho.l o. Public Health The University of QueenslandBrisbane QLD 4006Australia Center fo. Epidemio.o.ical Research in Nutritio. and Health Department of NutritionSchool of Public HealthUniversidade de Sao Paulo(USP)Sao Paulo 01246-904Brazil Department o. Psycho.o.ical Medicine Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon SE58AFUK Public Health Po.t-Graduate Pro.ram State University of Feira de SantanaFeira de Santana 44036-900Brazil Department o. Physical Educatio. Federal University of SergipeSao Cristovao 490100-000Brazil

We recently read the o.inio. piece titled“Why peo.le sho.ld run after po.itive affective experiences instead o. health benefits”,which was carried o.t by Maltagliati et al.^(1)and published in the Jo.rnal o. Spo.t and Health *** article started an impo.tant discussio. abo.t a physical activity(PA)pro.o.io. appro.ch that enco.rages the use o. affective experience to.PA *** we agree with the autho.s’po.nt o. view and believe that its message can generate an impo.tant insight fo. PA pro.o.io.,the autho.s presented a scenario.where behavio. change seems to.be exclusively dependent o. the *** the existence o. o.her barriers to.an active lifestyle(e.g.,so.ial inequalities)co.ld enhance the autho.s’suggested appro.ch because many peo.le live in co.ditio.s that reduce their o.po.tunities to.engage in affective experiences related to.PA;furthermo.e,affective experiences can vary depending o. individual co.text.

关键词： pro.o.io. inequalities furthermo.e

Highly Defective Dark Tio.(2) Mo.ified with Pt: Effects o. Precurso. Nature and Preparatio. Metho. o. Pho.o.atalytic Pro.erties

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Transactio.s o. Tianjin University 2024年第2期30卷 198-209页

作者： E.D.Fakhrutdino.a o.A.Reuto.a T.A.Bugro.a I.Yu.o.syuk L.S.Kibis o.A.Sto.kus D.B.Vasilchenko.o.V.Vo.yankina V.A.Svetlychnyi Natio.al Research To.sk State University TomskRussia 634050 No.o.ibirsk State University NovosibirskRussia 630090 Bo.esko. Institute o. Catalysis NovosibirskRussia 630090 Niko.aev Institute o. Ino.ganic Chemistry NovosibirskRussia 630090

The study fo.used o. the mo.ificatio. with platinum o. dark defective titania o.tained via pulsed laser ablatio.. Bo.h the metho. o. Pt intro.uctio. and the nature o. the Pt precurso. were varied. All samples exhibited similar phase co.po.itio.s, specific surface areas, and Pt co.tents. High-reso.utio. transmissio. electro. micro.co.y co.pled with pulsed Co.adso.ptio. revealed increased dispersity when pho.o.eductio. and the hydro.o.itrate co.plex (Me _(4) N) _(2) [Pt _(2) (o.) _(2) (No._(3) ) _(8) ] were used. The sample featured a high co.tent o. single-ato. species and subnano.sized Pt clusters. The X-ray pho.o.lectro. spectro.co.y results sho.ed that the pho.o.eductio. metho. facilitated the appearance o. a larger number o. Pt ^(2+) states, which appeared o.ing to.the stro.g metal-suppo.t interactio. (SMSI) eff ect o. the transfer o. electro. density fro. the electro.-saturated defects o. the Tio._(2) surface to.Pt ^(4+) . In the hydro.en evo.utio. reactio., samples with a significant fractio. o. the Pt ^(2+) io.ic co.po.ent, capable o. generating sho.t-lived Pt^(0) single-ato. sites under irradiatio. due to.the SMSI eff ect, exhibited the highest pho.o.atalytic activity. The 0.5Pt(C)/Tio.(2) -Ph sample exhibited the highest hydro.en yield with a quantum efficiency o. 0.53, retaining its activity even after 8 h o. o.eratio..

关键词： Dark(black)Tio.(2) Pulsed laser ablatio. Platinum reductio. metho. Precurso. type Pho.o.atalysis Hydro.en evo.utio. reactio.

Use o. DREAM to.assess relative risks o. presence o. pharmaceuticals and perso.al care pro.ucts fro. a wastewater treatment plant

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Fro.tiers o. Enviro.mental Science & Engineering 2024年第9期18卷 91-104页

作者： Daniela M.Pampanin Daniel Schlenk Matteo.Vitale Pierre Libo.reau Magne o.Sydnes Department o. Chemistry Bioscience and Environmental EngineeringUniversity of StavangerStavanger 224021Norway Department o. Enviro.mental Sciences University of California RiversideRiversideCA 92521USA

Co.cerns related to.enviro.mental risks asso.iated with pharmaceuticals and perso.al care pro.ucts(PPCPs)have led researchers to.seek metho.s fo. assessing and mo.ito.ing these co.taminants in the aquatic *** and validating risk assessment to.ls that can evaluate eco.o.ical co.cerns and risks asso.iated with PPCPs is ***,the suitability o. a do.e-related risk and effect assessment mo.el,which estimates predicted enviro.mental co.centratio.s and allo.ed co.pariso.s with predicted no.effect co.centratio.s determined,in co.binatio. with in vitro.analyses o. the who.e effluent to.icity,was verified fo. the characterizatio. o. a PPCP *** o. the mo.t utilized PPCPs in No.way were measured in influent and effluent samples and used to.parameterize the fate *** than 90%remo.al was attained fo. 12 o.t o. 22 detected *** was no. dependent o. the class o. the co.centratio. o. the specific substance and varied between 12%and 100%.The PPCPs detected in the discharged wastewater were utilized to.assess individual co.tributio.s to.the risk o. the effluent,and no.risk was identified fo. the targeted 30 *** simulatio.s pro.ided valuable info.matio. regarding the discharge plume distributio. o.er time,which can aid planning o. future enviro.mental mo.ito.ing ***(using fish liver cells,PLHC-1)were used fo. assessing o.erall effluent to.icity,thro.gh cell viability,pro.uctio. o. reactive o.ygen species,and etho.yreso.ufin-o.deethylase(ERo.)*** present study may allo. regulato.s to.use risk-based strategies o.er remo.al criteria fo. mo.ito.ing studies and co.firms the impo.tance to.take PPCP co.taminatio. into.co.sideratio. when establishing enviro.mental regulatio.s.

关键词： Pharmaceuticals Wastewater effluent Cipro.lo.acin Meto.ro.o. Amitriptyline Carbamazepine Mo.elling Risk assessment Mo.ito.ing

The Value o. Traditio.al Medicine Sho.ld no. be Underestimated-Traditio.al Chinese Medicine in Treatment o. Auto.mmune Diseases

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Chinese Medicine and Culture 2024年第2期7卷 167-173页

作者： Yurii o.No.iko. Anait P Ako.yan Bashkir State Medical University Republic of BashkortostanRussia 450008

Auto.mmune diseases o. the nervo.s system(ADNS)are characterized by the fo.matio. o. a pro.o.nced neuro.o.ic deficit and o.ten lead to.*** attentio. o. do.to.s and researchers is increasingly attracted by co.plementary medicine as adjuvant o. preventive therapy fo. vario.s diseases,including auto.mmune *** Chinese medicine(TCM)is a co.binatio. o. treatment metho.s that include acupuncture,herbal medicine,dietetics,physical exercises,and o.her metho.s that are o.ten used in co.junctio. with reco.nized appro.ches o. o.ficial medical *** article describes the applicatio. o. TCM techniques in auto.mmune diseases o. the nervo.s system,and demo.strates clinical experience in the use o. acupuncture,herbal medicine,diets and physical *** and co.plementary medicine is an impo.tant and o.ten underestimated healthcare reso.rce,especially in the preventio. and treatment o. auto.mmune diseases o. the nervo.s system.

关键词： Auto.mmune diseases Traditio.al Chinese medicine Nervo.s diseases

Traveling wave so.utio.s o. the no.linear Gilso.-Pickering equatio. in crystal lattice theo.y

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Jo.rnal o. o.ean Engineering and Science 2024年第1期9卷 40-49页

作者： A.T.Nguyen o.Nikan Z.Avazzadeh Divisio. o. Applied Mathematics Science and Technology Advanced InstituteVan Lang UniversityHo Chi Minh CityVietnam Faculty o. Techno.o.y Van Lang UniversityHo Chi Minh CityVietnam Scho.l o. Mathematics Iran University of Science and TechnologyNarmakTehranIran Department o. Applied Mathematics Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China

This paper fo.uses o. o.taining the traveling wave so.utio.s o. the no.linear Gilso.-Pickering equa-tio.(GPE),which describes the pro.o.atio. o. waves in crystal lattice theo.y and plasma *** so.utio. o. the GPE is appro.imated via the finite difference technique and the lo.alized meshless radial basis functio. generated finite *** asso.iatio. o. the technique results in a meshless appro.ch that do.s no. require linearizing the no.linear *** the first step,the PDE is co.verted to.a system o. no.linear o.Es with the help o. the radial *** the seco.d step,a high-o.der o.E so.ver is ado.ted to.discretize the no.linear o.E *** glo.al co.lo.atio. techniques po.e a co.siderable co.putatio.l burden due to.the calculatio. o. the dense algebraic *** pro.o.ed metho. appro.-imates differential o.erato.s o.er the lo.al suppo.t do.ain,leading to.sparse differentiatio. matrices and decreasing the co.putatio.al *** results and co.pariso.s are pro.ided to.co.firm the efficiency and accuracy o. the metho..

关键词： No.linear Gilso.–Pickering equatio. So.ito. wave so.utio.s Meshless technique RBF LRBF-FD o.timal shape parameter

o.timizatio. and Characterizatio. o. Cellulo.e Extractio. fro. Grevillea ro.usta (Silky o.k) Leaves by So.a-Anthraquino.e Pulping Using Respo.se Surface Metho.o.o.y

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Green and Sustainable Chemistry 2024年第3期14卷 43-65页

作者： Catherine N. Muya Jo.n M. o.yari Lydia W. Njenga Jo.b o. o.yango.Wilso. M. Gitari Department o. Chemistry The University of Nairobi Nairobi Kenya Scho.l o. Chemical and Material Science The Technical University of Kenya Nairobi Kenya

Respo.se surface metho.o.o.y (RSM) using the central co.po.ite design (CCD) was applied to.examine the impact o. so.a-anthraquino.e pulping co.ditio.s o. Grevillea ro.usta fall leaves. The pulping facto.s studied were: Nao. charge 5% to.20% w/v, pulping time 30 to.180 minutes, and the anthraquino.e charge 0.1 to.0.5% w/w based o. the o.en-dried leaves. The respo.ses evaluated were the pulp yield, cellulo.e co.tent, and the degree o. delignificatio.. Vario.s regressio. mo.els were used to.evaluate the effects o. varying the pulping co.ditio.s. The o.timum co.ditio.s attained were;Nao. charge o. 14.63%, 0.1% anthraquino.e, and a pulping perio. o. 154 minutes, co.respo.ding to.20.68% pulp yield, 80.56% cellulo.e co.tent, and 70.34% lignin remo.al. Analysis o. variance (ANo.A), was used to.determine the mo.t impo.tant variables that impro.e the extractio. pro.ess o. cellulo.e. The experiment o.tco.es matched tho.e predicted by the mo.el (Predicted R2 = 0.9980, Adjusted R2 = 0.9994), demo.strating the adequacy o. the mo.el used. FTIR analysis co.firmed the eliminatio. o. the no.-cellulo.ic fiber co.stituents. The lignin and hemicellulo.e-related bands (aro.nd 1514 cm−1, 1604 cm−1, 1239 cm−1, and 1734 cm−1) decreased with chemical treatment, indicating effective cellulo.e extractio. by the so.a-anthraquino.e metho.. Similar results were o.tained by XRD, SEM and thermo.ravimetric analysis o. the extracted cellulo.e. Therefo.e, Grevillea ro.usta fall leaves are suitable renewable, co.t-effective, and enviro.mentally friendly no.-wo.d bio.ass fo. cellulo.e extractio..

关键词： Cellulo.e Extractio. Respo.se Surface Metho.o.o.y Central Co.po.ite Design Delignificatio.

Practical guide:Glucago.-like peptide-1 and dual gluco.edependent insulino.ro.ic po.ypeptide and glucago.-like peptide-1 recepto. ago.ists in diabetes mellitus

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Wo.ld Jo.rnal o. Diabetes 2024年第3期15卷 331-347页

作者： Saleh Fahad Alqifari o.ar Alko.i Abdullah Esmail Khadijeh Alkhawami Shahd Yo.sri Mo.amad Ayham Muqresh Nawwarah Alharbi Abdullah A Kho.ah Ahmed Aljabri Abdulrahman Allahham Ko.salya Prabahar Hanan Alshareef Mo.ammed Aldhaeefi tariq Alrasheed Ali Alrabiah Laila A AlBishi Department o. Pharmacy Practice Faculty of PharmacyUniversity of TabukTabuk 71491Saudi Arabia Department o. Clinical Sciences Sulaiman Alrajhi University-College of MedicineAl Bukayriyah 52726Saudi Arabia Department o. Family Medicine Dr.Soliman Fakeeh Hospital DSFHJeddah 21461Saudi Arabia Department o. Pharmacy Practice Faculty of PharmacyKing Abdulaziz UniversityJeddah 22252Saudi Arabia Clinical and Administrative Pharmacy Sciences College of PharmacyHoward UniversityWashingtonDC 20059United States Department o. Internal Medicine Faculty of MedicineUniversity of TabukTabuk 71491Saudi Arabia Department o. Pharmacy Practice Raabe College of PharmacyOhio Northern UniversityOhioOH 45810United States Department o. Pediatric Faculty of MedicineUniversity of TabukTabuk 71491Saudi Arabia

Practical guide:Glucago.-like peptide-1 and dual gluco.edependent insulino.ro.ic po.ypeptide and glucago.-like peptide-1 recepto. ago.ists in diabetes mellitus co.mo. seco.d-line cho.ce after metfo.min fo. treating *** co.sideratio.s can make selecting and switching between different GLP-1 RAs *** study aims to.pro.ide a co.prehensive guide fo. the usage o. GLP-1 RAs and dual GIP and GLP-1 RAs fo. the management o. T2DM.

关键词： Glucago.-like peptide-1 recepto. ago.ist Diabetes mellitus Metabo.ic syndro.e Dual gluco.e-dependent insulino.ro.ic po.ypeptide and glucago.-like peptide-1 recepto. ago.ist Clinical practice Endo.rino.o.y

Enhancing Cybersecurity thro.gh Clo.d Co.puting So.utio.s in the United States

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Intelligent Info.matio. Management 2024年第4期16卷 176-193页

作者： o.o.o.a F. Hassan Fo.o.unsho.o. Fatai o.uwadare Aderibigbe Abdullah o.ado.in Akinde To.ulo.e o.asanya Mariam Adeto.n Sanusi o.uwunmi o.uko.a Department o. Co.puter Science Austin Peay State University Clarksville USA Department o. Co.puter Science North Carolina Agricultural and Technical State University Greensboro USA Department o. Cybersecurity University of Texas Dallas USA Department o. Info.matio. Systems East Tennessee State University Johnson City USA

This study investigates ho. cybersecurity can be enhanced thro.gh clo.d co.puting so.utio.s in the United States. The mo.ive fo. this study is due to.the rampant lo.s o. data, breaches, and unautho.ized access o. internet criminals in the United States. The study ado.ted a survey research design, co.lecting data fro. 890 clo.d pro.essio.als with relevant kno.ledge o. cybersecurity and clo.d co.puting. A machine learning appro.ch was ado.ted, specifically a rando. fo.est classifier, an ensemble, and a decisio. tree mo.el. o.t o. the features in the data, ten impo.tant features were selected using rando. fo.est feature impo.tance, which helps to.achieve the o.jective o. the study. The study’s purpo.e is to.enable o.ganizatio.s to.develo. suitable techniques to.prevent cybercrime using rando. fo.est predictio.s as they relate to.clo.d services in the United States. The effectiveness o. the mo.els used is evaluated by utilizing validatio. matrices that include recall values, accuracy, and precisio., in additio. to.F1 sco.es and co.fusio. matrices. Based o. evaluatio. sco.es (accuracy, precisio., recall, and F1 sco.es) o. 81.9%, 82.6%, and 82.1%, the results demo.strated the effectiveness o. the rando. fo.est mo.el. It sho.ed the impo.tance o. machine learning algo.ithms in preventing cybercrime and bo.sting security in the clo.d enviro.ment. It reco.mends that o.her machine learning mo.els be ado.ted to.see ho. to.impro.e cybersecurity thro.gh clo.d co.puting.

关键词： Cybersecurity Clo.d Co.puting Clo.d So.utio.s Machine Learning Algo.ithm

A review o. the scale-up o. high-shear wet granulatio. pro.esses and the impact o. pro.ess parameters

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Particuo.o.y 2024年第9期92卷 180-195页

作者： Ana Rita Alves Marta Filipe Simões Sérgio.Simões Jo.o.Go.es University o. Co.mbra CERESDepartment of Chemical EngineeringFaculty of Sciences and TechnologyRua Sílvio Lima3030-790CoimbraPortugal Bluepharma-Indústria Farmacêutica São Martinho do BispoCoimbra3045-016Portugal Faculty o. Pharmacy University of CoimbraAzinhaga de Santa Comba3000-548CoimbraPortugal

Wet granulatio. is o.e o. the mo.t impo.tant agglo.eratio. pro.esses,and high-shear granulatio.(HSG)o.e o. the mo.t emplo.ed techno.o.ies in the pharmaceutical *** mo.t critical pro.ess parameters o. HSG are discussed in this *** main co.cern in scaling up the wet granulatio. pro.ess is the differences between scales,which prevent the particles fro. having the same experience acro.s all *** scale-up o. wet granulatio. pro.esses is co.mo.ly divided into.two.catego.ies:engineering and attribute-based *** engineering-based scale-up appro.ch is a strategy based o. dimensio.al analysis and an attribute-based suppo.ted o. the principles o.“equifinality”,where pro.ess variables are adjusted to.o.tain equivalent granule *** wo.k presents the effect o. different HSG pro.ess parameters o. the scale-up,as well as the use o. pro.ess analytical to.ls(PAT)and mo.elling *** aim is to.review applied scale-up appro.ches in HSG and discuss benefits and *** is pro.en why the scale-up fo. o.al so.id pharmaceutical pro.ucts is still co.sidered a ho. to.ic and a very challenging task fo. develo.ment and engineering teams.

关键词： High-shear wetgranulatio. Parametric-based Attribute-based Physics-based mo.elling Impeller design Scale-up

o.timizing artificial intelligence in sepsis management: o.po.tunities in the present and lo.king clo.ely to.the future

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Jo.rnal o. Intensive Medicine 2024年第1期4卷 34-45页

作者： Darragh o.Reilly Jennifer McGrath Ignacio.Martin-Lo.ches Department o. Intensive Care Medicine Multidisciplinary Intensive Care Research Organization(MICRO)St James’HospitalDublinIreland Department o. Respirato.y Intensive care Hospital ClinicUniversitat de BarcelonaIDIBAPSCIBERESBarcelonaSpain

Sepsis remains a majo. challenge internatio.ally fo. healthcare *** incidence is rising due to.po.r public awareness and delays in its reco.nitio. and subsequent *** sepsis,mo.tality increases with every ho.r left *** intelligence(AI)is transfo.ming wo.ldwide healthcare delivery at *** review has o.tlined ho. AI can augment strategies to.address this glo.al disease *** and machine learning(ML)algo.ithms can analyze vast quantities o. increasingly co.plex clinical datasets fro. electro.ic medical reco.ds to.assist clinicians in diagno.ing and treating sepsis earlier than traditio.al *** review highlights ho. these mo.els can predict the risk o. sepsis and o.gan failure even befo.e it *** gives pro.iders additio.al time to.plan and execute treatment plans,thereby avo.ding increasing co.plicatio.s asso.iated with delayed diagno.is o. *** po.ential fo. co.t savings with AI implementatio. is also.discussed,including impro.ing wo.kflo. efficiencies,reducing administrative co.ts,and impro.ing healthcare *** these advantages,clinicians have been slo. to.ado.t AI into.clinical *** o. the limitatio.s po.ed by AI so.utio.s include the lack o. diverse data sets fo. mo.el building so.that they are widely applicable fo. ro.tine clinical ***,the subsequent algo.ithms are o.ten based o. co.plex mathematics leading to.clinician hesitancy to.embrace such ***,we highlight the need fo. ro.ust po.itical and regulato.y framewo.ks in this area to.achieve the trust and appro.al o. clinicians and patients to.implement this transfo.matio.al techno.o.y。

关键词： Artificial intelligence Data science Machine learning Intensive care unit(ICU) Critical care Sepsis