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Human recombinant soluble ACE2(hrsACE2)shows promise for treating severe COVID19

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Signal Transduction and Targeted Therapy 2020年第1期5卷 303-304页

作者： tarek Mohamed Abd el-Aziz Ahmed Al-Sabi James D.Stockand Department of Cellular and Integrative Physiology University of Texas Health Science Center at San AntonioSan AntonioTX 78229-3900USA Zoology Department Faculty of ScienceMinia UniversityEl-Minia 61519Egypt College of Engineering and Technology American University of the Middle EastKuwaitKuwait

A recent study by Zoufaly et *** in The Lancet Respiratory Medicine describes encouraging data from the first severe COVID-19 patient successfully treated with human recombinant soluble angiotensin-converting enzyme-2(hrsACE2).1 The published data document upon treatment of an adaptive immune response,the disappearance of the virus swiftly from the serum,the nasal cavity and lungs,and a reduction of inflammatory cytokine levels that are critical for COVID-19 ***,the use of hrsACE2 did not impede the generation of neutralizing antibodies,leading to a significant clinical improvement of the treated patient.

关键词： ACE2 al cavity

Assessing effects of deficit irrigation techniques on water productivity of tomato for subsurface drip irrigation system

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International Journal of Agricultural and Biological Engineering 2018年第4期11卷 156-167页

作者： Mahmoud S Hashem tarek Zin el-Abedin Hussein M Al-Ghobari Agricultural Engineering Department College of Food and Agriculture SciencesKing Saud UniversityRiyadh 11451Saudi Arabia Agricultural Engineering Research Institute(AEnRI) Agricultural Research CenterGizaEgypt Agricultural Engineering Department College of AgricultureAlexandria UniversityAlexandriaEgypt

Water resources are subjected to ever-increasing supply constraints due to extensive agricultural water demand for irrigated ***,water-saving irrigation strategies need to be *** present study was conducted to explore the possibilities of using regulated deficit irrigation(RDI)and partial root zone drying irrigation(PRD)methods as water-saving irrigation techniques for subsurface *** objective of this study are to assess the effects of RDI and PRD irrigation on the water productivity of vegetable crops(tomato)under SSD systems in arid climatic conditions,and to compare the responses of tomato crops to PRD,RDI,and FI under an SSD system in terms of productivity,crop quality,and the amount of water *** field experiment was conducted during the fall 2014-2015 and 2015-2016 seasons in an experimental field located on an educational farm owned by the Faculty of Food and Agriculture Sciences Department,King Saud University,Riyadh,Kingdom of Saudi *** area of 102.7 m^(2)(13 m×7.9 m)was allocated for the experiment to manage three treatments:RDI,PRD,and full irrigation(FI).The RDI and PRD treatments received 70%of the irrigation water volume of *** was replicated three *** most important results indicated that the soil water content(SWC)for the RDI and PRD treatments was lower than that of the FI *** had the highest stomatal conductance values(gs),while PRD had the lowest stomatal conductance *** photosynthetic rate(A_(n))was lower under RDI and PRD compared to ***,there was no significant change in A_(n) between treatments for most readings taken during both time periods,which means that the water saving treatments(PRD and RDI)did not affect the net photosynthesis rate,thereby enhancing irrigation water use efficiency(IWUE)under DI *** water-saving irrigation techniques decreased transpiration rate(T)compared to the FI *** values of the abscisic acid(ABA)contents were higher

关键词： full irrigation(FI) regulated deficit irrigation(RDI) partial root zone drying(PRD) irrigation water use efficiency(IWUE)

Effect of single subconjunctival injection of bevacizumab on primary pterygium:clinical,histopathological and immunohistochemical study

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International Journal of Ophthalmology(English edition) 2018年第5期11卷 797-801页

作者： tarek A Mohamed Wael Soliman Ahmed M.Fathalla Abeer el Refaie Department of Ophthalmology Assiut University Hospital Department of Pathology Faculty of MedicineAssiut University

AIM：To evaluate the effect（clinically,histopathologically and immunohistochemically） and safety of a single intrapterygium injection of ***：Prospective interventional study comprised 40 eyes of 40 patients with primary fleshy pterygia who attended the Outpatient Clinic of Department of Ophthalmology,Assiut University Hospitals,Egypt from May 2015 to May *** were randomly classified into 2 groups：the first group received a single intralesional injection of bevacizumab（Avastin;Genentech,San Francisco,CA,USA）;the second group comprised patients who did not receive subconjunctival *** of pterygium and conjunctival auto graft was done in both *** excised pterygium tissues were subjected to histopathological and immunohistochemical ***：The study comprised 40 eyes of 40 patients（33 men,7 women） of age range from 31-58 *** study group included 22 *** control group included 18 eyes.A decrease in the vascularity of the pterygium was noted in all injected *** mean vessel count was higher in non-injected pterygia than that in injected pterygia and the difference was statistically significant（P=0.001）.Also,the mean vessel count in both groups was significantly higher than normal conjunctive（P=0.005 and 0.001）.A statistically significant difference in vascular endothelial growth factor（VEGF） expression between injected and non-injected cases was detected in the epithelial,stromal and endothelial cells（P=0.0001,0.016,0.014）.No serious intraoperative complications occurred in both ***：The use of single intra lesional injection of Avastin in pterygium decreased vascularity and decreased VEGF expression in injected pterygium after one *** study proved the effect of single intra lesional injection of Avastin on *** studies may enable limiting the need for surgery and improve quality of life for patients with pterygia.

关键词： pterygiurn vascularity bevacizumab vessel count

Prediction of fold-of-increase in productivity index post limited entry fracturing using artificial neural network

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Petroleum Research 2022年第2期7卷 236-245页

作者： Shady Galal Ramah Mohamed Abdalla Othman Ahmed Z.Nouh tarek el-Kwidy Faculty of Petroleum Engineering Suez UniversityEgypt Qarun Petroleum Company Egypt Egyptian Petroleum Research Institute Egypt American University in Cairo Egypt

Unified Fracture Design(UFD)bridges the gap between practices and theory in the hydraulic fracturing *** represents a technique to design hydraulic fracturing treatment with a particular amount of *** design could provide the maximum fold-of-increase(FOI)in productivity-index(PI)after hydraulic fracturing *** UFD optimization tool is very effective,but it has assumptions like any other *** assumption of UFD optimization technique;is a single-layer *** assumption does not align with the limited entry fracturing design *** limited entry fracturing,the frictional pressure is employed to offset the stress differences between multi-layers reservoirs to attain fluid injection through these layers,intended to deliver an optimal fracture conductivity in all *** drawback of this assumption is the underestimation of the actual value of FOI in *** paper aims to recast the original unified fracture design approach to extend the optimal UFD to a multilayer reservoir to predict the FOI in PI after limited entry fracturing *** recasting tool for this problem to find the optimum solution is Artificial Neural Networks(ANN).The architected ANN model is based on actual historical data of limited entry fracturing treatments.A statistical comparison between the proposed ANN model and classical UFD technique demonstrates that ANN model solution has a more reliable estimation of FOI in PI with the actual historical data.

关键词： Unified fracture design Hydraulic fracturing Limited-entry Fold of increase Artificial neural networks

Histopathological changes in the oesophageal mucosa in Egyptian children with corrosive strictures: A single-centre vast experience

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World Journal of Gastroenterology 2019年第7期25卷 870-879页

作者： Ayman EskANDer Carolyne Ghobrial Nabil A Mohsen Bahaa Mounir Dalia Abd el-Kareem Sara tarek Mortada HF el-Shabrawi Department of Paediatrics Kasr Alainy School of Medicine Cairo University Department of Pathology Kasr Alainy School of Medicine Cairo University

BACKGROUND The caustic ingestion continues to be a major problem worldwide especially in developing countries. The long-term complications include stricture and increased life time risk of oesophageal carcinoma. Patients suffered from corrosive induced oesophageal strictures have more than a 1000-fold risk of developing carcinoma of the *** To determine the possibility of oesophageal mucosal dysplasia after prolonged dilatation in post corrosive *** This observational study was conducted at the Paediatric Endoscopy Unit in Cairo University Children's Hospital. It included children of both sexes older than 2 years of age who had an established diagnosis of post-corrosive oesophageal stricture and repeated endoscopic dilatation sessions for more than 6 mo. All patients were biopsied at the stricture site after 6 mo of endoscopic dilatation. A histopathological examination of an oesophageal mucosal biopsy was performed for the detection of chronic oesophagitis, inflammatory cellular infiltration and *** The mean age of the enrolled children was 5.9 ± 2.6 years; 90% of the patients had ingested an alkaline corrosive substance(potash). The total number of endoscopic dilatation sessions were ranging from 16 to 100 with mean number of sessionswas 37.2 ± 14.9. Histopathological examination of the specimens showed that 85%of patients had evidence of chronic oesophagitis(group A) in the form of basal cell hyperplasia, hyperkeratosis and subepithelial fibrosis. Thirteen percent of the patients had evidence of reactive atypia(group B) in the form of severe neutrophilic intraepithelial inflammatory cellular infiltration, and 2 patients(2%)had mild squamous dysplasia(group C); we rebiopsied these two patients 6 mo after the initial pathological assessment, guided by chromoendoscopy by Lugol's *** The histopathology of oesophageal mucosal biopsies in post-corrosive patients demonstrates evidence of chronic oesophagitis, intraepi

关键词： Children Endoscopic dilatation Dysplasia Oesophageal strictures Postcorrosive

Wind Power Prediction Based on Machine Learning and Deep Learning Models

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Computers, Materials & Continua 2023年第1期74卷 715-732页

作者： Zahraa tarek Mahmoud Y.Shams Ahmed M.elshewey el-Sayed M.el-kenawy Abdelhameed Ibrahim Abdelaziz A.Abdelhamid Mohamed A.el-dosuky Faculty of Computers and Information Computer Science DepartmentMansoura UniversityMansoura35561Egypt Faculty of Artificial Intelligence Kafrelsheikh UniversityKafrelsheikh33511Egypt Faculty of Computers and Information Computer Science DepartmentSuez UniversitySuezEgypt Department of Communications and electronics Delta Higher Institute of Engineering and TechnologyMansoura35111Egypt Faculty of Artificial Intelligence Delta University for Science and TechnologyMansoura35712Egypt Computer Engineering and Control Systems Department Faculty of EngineeringMansoura UniversityMansoura35516Egypt Department of Computer Science Faculty of Computer and Information SciencesAin Shams UniversityCairo11566Egypt Department of Computer Science College of Computing and Information TechnologyShaqra University11961Saudi Arabia Department of Computer Science Arab East CollegesRiyadh13544Saudi Arabia

Wind power is one of the sustainable ways to generate renewable *** recent years,some countries have set renewables to meet future energy needs,with the primary goal of reducing emissions and promoting sustainable growth,primarily the use of wind and solar *** achieve the prediction of wind power generation,several deep and machine learning models are constructed in this article as base *** regression models are Deep neural network(DNN),k-nearest neighbor(KNN)regressor,long short-term memory(LSTM),averaging model,random forest(RF)regressor,bagging regressor,and gradient boosting(GB)*** addition,data cleaning and data preprocessing were performed to the *** dataset used in this study includes 4 features and 50530 *** accurately predict the wind power values,we propose in this paper a new optimization technique based on stochastic fractal search and particle swarm optimization(SFSPSO)to optimize the parameters of LSTM *** evaluation criteria were utilized to estimate the efficiency of the regression models,namely,mean absolute error(MAE),Nash Sutcliffe Efficiency(NSE),mean square error(MSE),coefficient of determination(R2),root mean squared error(RMSE).The experimental results illustrated that the proposed optimization of LSTM using SFS-PSO model achieved the best results with R2 equals 99.99%in predicting the wind power values.

关键词： Prediction of wind power data preprocessing performance evaluation

Synthesized graphene oxide and fumed aerosil 380 dispersion stability and characterization with partially hydrolyzed polyacrylamide

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Chinese Journal of Chemical Engineering 2021年第6期34卷 307-322页

作者： Najeebullah Lashari tarek Ganat Department of Petroleum Engineering Universiti Teknologi PETRONAS32610 Seri IskandarPerak Darul RidzuanMalaysia Department of Petroleum and Gas Engineering Dawood University of Engineering&TechnologyM.A Jinnah RoadKarachi 74800Pakistan

Hydrolyzed polyacrylamide(HPAM)is a commonly used polymer for the chemicals,mining and refining processes of hydrocarbon but suffers from a persistent high-temperature instability *** contrast,the nanoparticle suspension remains a technical challenge because of the strong interactions of van der Waal forces within nanoparticles,which always encourage *** research sought to improve nanoparticles(NP)stability and polymer(HPAM)rheological properties to improved hydrocarbon recovery by utilizing synthesized graphene oxide(GO)nanosheets and fumed Aerosil 380 Silica oxide(SiO_(2)).The aqueous nanocomposites based on HPAM-GO and HPAM-SiO_(2) in aqueous polymeric solutions have been developed,and its viscoelastic and static behaviour is *** results imply that by adding fumed silica NP,the viscoelastic behaviour of HPAM is marginally improved,particularly in high temperatures and salinity,however,the inclusion of GO's significantly improves the viscosity and stability of the base polymer fluid at high *** Fourier data for the transformation of the infrared spectrum confirmed that the hydrogen bonding formed between HPAM carbonyl groups and silica NP surface silanol functionality and covalent interlinking of electrostatic h-bonding between HPAM and functional GO contributed to the improved stabilization and improved rheological performance that helps to recover high salinity and temperature hydrocarbons.

关键词： Aggregation Composites Chemical enhance oil recovery Hydrocarbons Nanoparticles Polymer

Emerging applications of nanomaterials in chemical enhanced oil recovery:Progress and perspective

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Chinese Journal of Chemical Engineering 2020年第8期28卷 1995-2009页

In enhanced oil recovery,different chemicalmethods utilization improves hydrocarbon recovery due to their fascinating abilities to alter some critical parameters in porous media,such as mobility control,the interaction between fluid to fluid,and fluid to rock *** decades the use of surfactant and polymer flooding has been used as tertiary recovery *** the current research,the inclusion of nanomaterials in enhanced oil recovery injection fluids solely or in the presence of other chemicals has got colossal *** emphasis of this review is on the applicability of nanofluids in the chemical enhanced oil *** responsiblemechanisms are an increment in the viscosity of injection fluid,decrement in oil viscosity,reduction in interfacial and surface tension,and alteration of wettability in the rock *** this review,important parameters are presented,which may affect the desired behavior of nanoparticles,and the drawbacks of nanofluid and polymer flooding and the need for a combination of nanoparticles with the polymer are *** to the lack of literature in defining the mechanism of nanofluid in a reservoir,this paper covers majorly all the previous work done on the application of nanoparticles in chemical enhanced oil recovery at home ***,the problems associatedwith the nano-enhanced oil recovery are outlined,and the research gap is identified,which must be addressed to implement polymeric nanofluids in chemical enhanced oil recovery.

关键词： Chemical enhanced oil recovery Mechanisms Nanoparticles Polymeric Nanofluids

The Effect of Core Eccentricity on the Structural Behavior of Concrete Tall Buildings

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Journal of Civil Engineering and Architecture 2024年第3期18卷 112-117页

作者： tarek Anwar Taha Awida Civil and Architecture Engineering Department College of EngineeringInternational University of Kuwait(IUK)Ardiya Government AreaKuwait

The main purpose of this paper is to investigate the effect of core eccentricity on the structural behavior of concrete tall *** buildings of 55 floors with plan dimensions 48.0×48.0 m2 were *** cases of main core locations are studied:centric(A),eccentric by one sixth(B)and one third(C)of building *** three-dimensional finite element method has been used in conducting structural analysis through ETABS *** and lateral(wind and seismic)loadings are applied to all building *** has been concluded that the core location is the prime parameter governing the structural behavior of tall *** the first two cases(A,B)have acceptable and similar structural behaviors conforming to code limits,in the third case(C),the building behavior came beyond code *** author introduced remedial action by adding two secondary cores in the opposite direction of the main core(C-R)to restore the building behavior to the code *** results of this action were satisfactory.

关键词： Concrete tall buildings core eccentricity structural behavior gravity wind seismic loadings