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International Journal of Ophthalmology(English edition) 2025年第1期18卷 94-102页

作者： Jia-Yin Qin Yan Liu tao wang Department of Ophthalmology Peking University International HospitalBeijing 102206China Beijing Key Laboratory of Ophthalmology and Visual Science Beijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical UniversityBeijing 100730China

AIM:To evaluate the efficacy and safety of microcatheterassisted 360-degree trabeculotomy combined with trabeculectomy(MATT-Trab)for treating refractory ***:Patients with refractory glaucoma who underwent MATT-Trab were retrospectively *** indicators for research statistics included the intraocular pressure(IOP)level,degree of decrease,changes in medication dosage,and success *** indicators included the best-corrected visual acuity and incidence of ***:This study comprised 31 patients,including 11 males and 20 females,with ages ranging from 8mo to 67y(mean age:29.40±22.10y).The average postoperative IOP at 1d,1wk,1mo,3mo,6mo,1y,and the last followup was significantly lower than the average preoperative IOP(31.33±9.24 mm Hg,P<0.05).The average number of postoperative medications at 1y was 0.48±1.51,which was significantly reduced compared to that used preoperatively(3.77±0.99,P=0.00).The absolute and qualified success rates were 45.16% and 83.87%,*** acuity exhibited no statistically significant difference between the postoperative and preoperative follow-up time points,except for the first day after *** most common postoperative complications were anterior chamber hemorrhage(25 cases,86.21%)and high IOP(10 cases,34.48%).CONCLUSION:Our results indicate that MATT-Trab is effective and safe for treating refractory glaucoma.

关键词： glaucoma refractor y glaucoma trabeculotomy trabeculectomy microcatheter

Effect of two-pass rolling of textured roll and polished roll on surface topography and mechanical properties of 316L stainless steel ultra-thin strip

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Journal of Iron and Steel Research International 2025年第1期32卷 186-197页

作者： Zeng-qiang Zhang Xi Liao Zhong-kai Ren Zhen-hua wang Ya-xing Liu tao wang Qing-xue Huang College of Mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan030024ShanxiChina Engineering Research Center of Advanced Metal Composites Forming Technology and Equipment of Ministry of Education Taiyuan University of TechnologyTaiyuan030024ShanxiChina National Key Laboratory of Metal Forming Technology and Heavy Equipment Taiyuan University of TechnologyTaiyuan030024ShanxiChina Shanxi TISCO Stainless Steel Precision Strip Co. Ltd.Taiyuan030032ShanxiChina

The textured roll and polished roll were applied instead of the ground roll in a 20-high mill to conduct two-pass rolling of 316L stainless steel strip with thickness of 0.027 *** the two-pass rolling with the textured roll and polished roll(TPR),the surface roughness of the strip is dramatically reduced,and the surface topographical anisotropy index is diminished to 30.9%of the initial *** with the strip rolled using the ground roll in both passes(GGR),the elongation of TPR rolled strip is obviously improved,and the mechanical property anisotropy is greatly *** anisotropy index of tensile strength and elongation are 42.58%and 52.59%of that of GGR rolled strip,which is mainly attributed to the significant decrease of the texture intensity of the strip by TPR *** results indicate that TPR process can obtain the stainless steel ultra-thin strip with smooth and uniform surface topography and good mechanical properties.

关键词： Textured roll Polished roll Surface topography Mechanical property Stainless steel ultra-thin strip

An integrated photocatalytic redox architecture for simultaneous overall conversion of CO_(2)and H_(2)O toward CH_(4)and H_(2)O_(2)

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Science Bulletin 2025年第3期70卷 373-382页

作者： Muhammad Salman Nasir Bowen Sheng Ying Zhao Haotian Ye Jun Song Jinglin Li Ping wang tao wang Xinqiang wang Zhen Huang Baowen Zhou Key Laboratory for Power Machinery and Engineering of Ministry of Education Research Center for Renewable Synthetic FuelSchool of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Artificial Microstructure and Mesoscopic Physics School of PhysicsNano-Optoelectronics Frontier Center of Ministry of Education(NFC-MOE)Peking UniversityBeijing 100871China Department of Mining and Materials Engineering McGill UniversityMontrealH3A 0G4Canada Electron Microscopy Laboratory School of PhysicsPeking UniversityBeijing 100871China Peking University Yangtze Delta Institute of Optoelectronics Nantong 226010China Collaborative Innovation Center of Quantum Matter School of PhysicsPeking UniversityBeijing 100871China

Solar-driven overall conversion of CO_(2)and H_(2)O into fuels and chemicals shows an ultimate strategy for carbon neutrality yet remains a huge ***,an integrated photocatalytic redox architecture of Zn NPs/GaN Nanowires(NWs)/Si is explored for light-driven overall conversion of CO_(2)and H_(2)O into CH_(4)and H_(2)O_(2)simultaneously without any external sacrificial agents and *** as-designed architecture affords a benchmark CH_(4)activity of 189 mmol gcat^(-1)h^(-1)with a high selectivity of 93.6%,in the synchronized formation of H_(2)O_(2)at a considerable rate of 25 m g^(-1)h^(-1).Moreover,a considerable turnover number of 27,280 mol CH_(4)per mol Zn was achieved over a long-term operation of 80 *** operando spectroscopic characterizations,isotope experiments,and density functional theory calculations,it is unraveled that Zn sites are synergetic with GaN to drive CO_(2)-to-CH_(4)conversion with a lowered energy barrier of 0.27 eV while inhibiting hydrogen evolution reaction with a relatively high energy barrier of 0.93 ***,owing to the unique surface properties of GaN,water is split into*OH and*H,followed by the formation of H_(2)O_(2)because of the alleviated adsorption strength of*OH by Zn ***,the hierarchical architecture enables the achievement of high activity and high selectivity of CH_(4)from CO_(2)reduction in distilled water along with the generation of H_(2)O_(2).This work provides an integrated photocatalytic redox architecture for the synchronized production of CH_(4)and H_(2)O_(2)with the only inputs of CO_(2),distilled water,and light.

关键词： Zn nanoparticles GaN nanowires/Si Integrated redox architecture Artificial photosynthesis CH_(4)and H_(2)0_(2)

17α-methyltestosterone induced hepatocyte apoptosis through endoplasmic reticulum stress in Takifugu fasciatus

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Journal of Oceanology and Limnology 2025年第1期43卷 219-231页

作者： Xuanyin CHEN Sheng LUO Yanfang LI Rui LI Xiaojun LI Zhengyang HU Shaowu YIN tao wang College of Marine Science and Engineering Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural TechnologyNanjing Normal UniversityNanjing 210023China Co-Innovation Center for Marine Bio-Industry Technology of Jiangsu Province Lianyungang 222005China

17α-methyltestosterone(17α-MT)is an emerging pollutant,which is harmful to the endocrine system and reproduction of *** investigated the effects of different concentrations of 17α-MT(0,5,30,60,and 100 mg/kg)on endoplasmic reticulum stress(ERS)and apoptosis in the liver of Takifugu *** show that:(1)with the increase of 17α-MT treatment concentration,liver transaminases(alanine aminotransferase;aspartate aminotransferase)and the mRNA expression of ERS marker genes(glucose-regulated protein 78;calreticulin)of *** were significantly increased compared with the control group(P<0.05);(2)the activity of succinate dehydrogenase(SDH),Caspase3 and Caspase9 in the liver of *** increased with the increase of 17α-MT concentration compared with the control group(P<0.05);(3)by using 4-phenylbutyricacid(4-PBA)inhibitors to stimulate ERS through in vitro experiments,the expression of ERS and apoptosis-related genes significantly decreased(P<0.05),and the apoptosis rate of *** hepatocytes was significantly inhibited(P<0.05)under 17α-MT *** study confirmed that ERS played an important role in the induction of apoptosis in the hepatocytes of ***,which enriched the ecotoxicological information of environmental androgens.

关键词： 17α-methyltestosterone Takifugu fasciatus liver endoplasmic reticulum stress apoptosis

Cholesterol metabolism: physiological versus pathological aspects in intracerebral hemorrhage

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Neural Regeneration Research 2025年第4期20卷 1015-1030页

作者： Ruoyu Huang Qiuyu Pang Lexin Zheng Jiaxi Lin Hanxi Li Lingbo Wan tao wang Department of Forensic Science School of Basic Medicine and Biological SciencesSuzhou Medicine College of Soochow UniversitySuzhouJiangsu ProvinceChina

Cholesterol is an important component of plasma membranes and participates in many basic life functions,such as the maintenance of cell membrane stability,the synthesis of steroid hormones,and *** plays a key role in the establishment and maintenance of the central nervous *** brain contains 20%of the whole body’s cholesterol,80%of which is located within myelin.A huge number of processes(e.g.,the sterol regulatory element-binding protein pathway and liver X receptor pathway)participate in the regulation of cholesterol metabolism in the brain via mechanisms that include cholesterol biosynthesis,intracellular transport,and *** brain injuries or diseases involving crosstalk among the processes above can affect normal cholesterol metabolism to induce detrimental ***,we hypothesized that cholesterol-related molecules and pathways can serve as therapeutic targets for central nervous system *** hemorrhage is the most severe hemorrhagic stroke subtype,with high mortality and *** cholesterol levels are associated with the risk of intracerebral ***,secondary pathological changes after intracerebral hemorrhage are associated with cholesterol metabolism dysregulation,such as neuroinflammation,demyelination,and multiple types of programmed cell *** cholesterol accumulation in the brain has been found after intracerebral *** this paper,we review normal cholesterol metabolism in the central nervous system,the mechanisms known to participate in the disturbance of cholesterol metabolism after intracerebral hemorrhage,and the links between cholesterol metabolism and cell *** also review several possible and constructive therapeutic targets identified based on cholesterol metabolism to provide cholesterol-based perspectives and a reference for those interested in the treatment of intracerebral hemorrhage.

关键词： cell death cholesterol metabolism intracerebral hemorrhage myelination therapeutic target

Platinum modification of metallic cobalt defect sites for efficient electrocatalytic oxidation of 5-hydroxymethylfurfural

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Journal of Energy Chemistry 2025年第2期101卷 463-473页

作者： Haoyu Zhan Baixue Cheng Yankun Lu Danning Xing Xingshuai Lv Huining Huang Thomas Frauenheim tao wang Peng Zhou State Key Laboratory of Bio-fibers and Eco-textiles College of Materials Science and Engineering Collaborative Innovation Center of Shandong Marine Biobased Fibers and Ecological Textiles Institute of Marine Biobased Materials Qingdao University Shandong Institute of Advanced Technology College of Chemistry and Chemical Engineering Ocean University of China Tianjin Key Laboratory of Advanced Functional Porous Materials Institute for New Energy Materials & Low-Carbon Technologies School of Materials Science and EngineeringTianjin University of Technology School of Science Constructor University Beijing Computational Science Research Center College of Chemistry and Molecular Engineering Qingdao University of Science and Technology

Co3O4possesses both direct and indirect oxidation effects and is considered as a promising catalyst for the oxidation of 5-hydroxymethylfurfural（HMF）.However,the enrichment and activation effects of Co3O4on OH-and HMF are weak,which limits its further *** defect engineering can regulate the electronic structure,optimize the adsorption of intermediates,and improve the catalytic activity by breaking the symmetry of the material,which is rarely involved in the upgrading of *** this work,we prepare Co3O4with metal defects and load the precious metal platinum at the defect sites（PtVco）.The results of in-situ characterizatio ns,electrochemical measurements,and theoretical calculations indicate that the reduction of Co-Co coordination number and the formation of Pt-Co bond induce the decrease of electron filling in the antibonding orbitals of Co *** resulting upward shift of the d-band center of Co combined with the characteristic adsorption of Pt species synergically enhances the enrichment and activation of organic molecules and OH species,thus exhibiting excellent HMF oxidation activity(including a lower onset potential（1.14 V） and 19 times higher current density than pure Co3O4at 1.35 V).In summary,this work explores the adsorption enhancement mechanism of metal defect sites modified by precious metal in detail,provides a new option for improving the HMF oxidation activity of cobalt-based materials,broadens the application field of metal defect based materials,and gives an innovative guidance for the functional utilization of metal defect sites in biomass conversion.

关键词： Adsorption enhancement Biomass upgrading Coordination environment Electrocatalysis Metallic defect

Macro-mechanics and Microstructure of Nanomaterial-modified Geopolymer Concrete: A Comprehensive Review

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 204-214页

作者： wang tao FAN Xiangqian GAO Changsheng QU Chiyu The National Key Laboratory of Water Disaster Prevention Nanjing Hydraulic Research InstituteNanjing 210024China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China School of Water Conservancy and Transportation Zhengzhou UniversityZhengzhou 450001China

We have described in detail the effects of nano-SiO_(2),nano-CaCO_(3),carbon nanotubes,and nano-Al_(2)O_(3) on geopolymer concrete from the perspectives of macro mechanics and *** existing research results show that the mechanism of nano-materials on geopolymer concrete mainly includes the filling effect,nucleation effect,and bridging effect,the appropriate amount of nano-materials can be used as fillers to reduce the porosity of geopolymer concrete,and can also react with Ca(OH)2 to produce C-S-H gel,thereby improving the mechanical properties of geopolymer *** optimum content of nano-SiO_(2) is between 1.0%and 2.0%.The optimum content of nano-CaCO_(3) is between 2.0%and 3.0%.The optimum content of carbon nanotubes is between 0.1%and 0.2%.The optimum content of nano-Al_(2)O_(3) is between 1.0%and 2.0%.The main problems existing in the research and application of nanomaterial-modified geopolymer concrete are summarized,which lays a foundation for the further application of nanomaterial in geopolymer concrete.

关键词： nanomaterials low carbon geopolymer concrete macro-mechanics microstructure

Prompt fission neutron uranium logging(Ⅱ):dead-time effect of the neutron time spectrum

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Nuclear Science and Techniques 2025年第2期36卷 82-94页

作者： Yan Zhang Chi Liu Shi-Liang Liu Hao-Ran Zhang Hai-tao wang Jin-Hui Qu Wen-Xing Hu Ren-Bo wang Bin Tang National Key Laboratory of Uranium Resources Exploration-Mining and Nuclear Remote Sensing East China University of TechnologyNanchang 330013China Fundamental Science on Radioactive Geology and Exploration Technology Laboratory East China University of TechnologyNanchang 330013China

The acquisition of neutron time spectrum data plays a pivotal role in the precise quantification of uranium via prompt fission neutron uranium logging(PFNUL).However,the impact of the detector dead-time effect remains paramount in the accurate acquisition of the neutron time ***,it is imperative for neutron logging instruments to establish a dead-time correction method that is not only uncomplicated but also practical and caters to various logging *** study has formulated an innovative equation for determining dead time and introduced a dead-time correction method for the neutron time spectrum,called the“dual flux method.”Using this approach,a logging instrument captures two neutron time spectra under disparate neutron *** carefully selecting specific“windows”on the neutron time spectrum,the dead time can be accurately *** substantiate its efficacy and discern the influencing factors,experiments were conducted utilizing a deuterium-tritium(D-T)neutron source,a Helium-3(3He)detector,and polyethylene shielding to collate and analyze the neutron time spectrum under varying neutron fluxes(at high voltages).The findings underscore that the“height”and“spacing”of the two windows are the most pivotal influencing ***,the“height”(fd)should surpass 2,and the“spacing”twd should exceed 200μ*** dead time of the 3 He detector determined in the experiment was 7.35μ*** the dead-time correction,the deviation of the decay coefficients from the theoretical values for the neutron time spectrum under varying neutron fluxes decreased from 12.4%to within 5%.Similarly,for the PFNUL instrument,the deviation in the decay coefficients decreased from 22.94 to 0.49%after correcting for the dead-time *** results demonstrate the exceptional efficacy of the proposed method in ensuring precise uranium *** dual flux method was experimentally validated as a universal approach applicable to pulsed neutron logging instrumen

关键词： PFNUL Neutron time spectrum Dead time Pulsed source Correction method

The CmCYC2 factors regulated the different biosynthesis and distribution of phenolic compounds in the capitulum of Chrysanthemum morifolium‘Hangju’

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Horticultural Plant Journal 2025年第1期11卷 336-350页

作者： Feng Yang Qiaosheng Guo Qingjun Zou Man Zhang Yong Su Shuyan Yu Jingzhe Pu tao wang Institute of Chinese Medicinal Materials Nanjing Agricultural UniversityNanjingJiangsu 210095China NMPA Key Laboratory for Quality Research and Evaluation of Traditional Chinese Medicine Anhui Institute for Food and Drug ControlHefeiAnhui 230051China

Chrysanthemum morifolium *** an important industrial crop with a high medicinal value,whose capitulum consists of ray and disc florets containing numerous bioactive components,such as flavonoids and phenolic ***,the distribution and accumulations of the bioactive metabolites in florets of Chrysanthemum morifolium were ***,the ray and disc florets of Chrysanthemum morifolium were separated for comparing the bioactive *** contents of phenolic compounds and antioxidant activities were significantly different between the two *** metabolomic analysis identified 203 and 241 differential metabolites between ray and disc florets at two flowering *** derivatives of quercetin,isorhamnetin,tricin,and caffeoylquinic acid were enriched in the disc florets,while apigenin,kaempferol,acacetin,and their glycosides mainly accumulated in the ray ***,the results of transcriptome and qRT-PCR suggested that the F3H,F3'H,and FLS genes highly expressed in disc florets,while the FNS gene was well expressed in ray florets,which explained the different distribution of phenolic compounds between ray and disc ***,the expression of CmCYC2 genes was found to be significantly related to the distribution of flavones by correlation *** was proved by the luciferase reporter assay that CmCYC2a and CmCYC2d factors could bind and activate the CmFNS promoter to regulate the flavones biosynthesis in ray *** results revealed the significant difference of metabolite contents and gene expression profile between ray and disc floret in Chrysanthemum morifolium and demonstrated that the quality of Chrysanthemum morifolium‘Hangju'was closely relevant to its flower morphology.

关键词： Chrysanthemum morifolium Ramat. Ray florets Disc florets Multi-omics analysis Flavonoids Phenolic acids

Classification criteria for coal bursting liability based on portable Leeb hardness testing

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Meitan Xuebao/Journal of the China Coal Society 2025年第1期50卷 297-310页

作者： Zhao, Yixin Yang, Zhe Xie, Ronghuan wang, tao Zhao, Liangchen Beijing Key Laboratory for Precise Mining of Intergrown Energy and Resources China University of Mining and Technology-Beijing Beijing100083 China School of Energy and Mining Engineering China University of Mining and Technology-Beijing Beijing100083 China Key Laboratory of Disaster Prevention and Disposal in Coal Mining Ministry of Emergency Management China University of Mining and Technology-Beijing Beijing100083 China

Determining the bursting liability of coal is one of the main basis for evaluating the bursting risk degree of coal burst mine. Considering the complexity of existing classification procedures for determining coal bursting liability, a new method based on portable Leeb hardness testing is proposed. Combined with the Leeb hardness test, longitudinal wave velocity test and uniaxial compression experiment on 20 specimens from four coal mines, a fitting relationship between coal Leeb hardness and rock mechanics parameters was established. The energy evolution law during the compression failure process of specimens with different Leeb hardness values were investigated. A coefficient KPE was defined to describe the energy release rate during the failure of specimens, and the correlation between KPE and traditional indicators of coal bursting liability was analyzed. Based on the relationship between Leeb hardness and KPE, a coal bursting liability classification criteria based on Leeb hardness was established. To validate the rationality of this criterion, its classification results were compared with those based on the national standards and the ejection mass ratio of coal cuttingsF. Two engineering application scenarios from a strong coal burst mine in the Ordos Basin were selected to further assess the criterion's effectiveness in practical applications. The results show that the Leeb hardness of coal demonstrates a strong correlation with uniaxial compressive strength and elastic modulus, whereas there is no significant correlation with longitudinal wave velocity. The larger the Leeb hardnessis, the stronger the energy storage and energy release of the specimens in uniaxial compression *** KPE values varied significantly among specimens with different bursting liabilities and showed strong correlation with traditional bursting liability indicators, indicating that KPE can be effectively used for coal bursting liability classification. The KPE of specimens was pos

关键词： Coal mines