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Natural convection in nanofluid enclosure under magnetic field:Entropy generation and economic analysis

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Propulsion and Power Research 2024年第2期13卷 273-293页

作者： Jiang-tao hu Shuo-Jun Mei School of Atmospheric Sciences Sun Yat-sen UniversityZhuhai 519082China School of Civil Engineering Central South University of Forestry and TechnologyChangsha 410004China hunan Province Key Laboratory of Engineering Rheology Central South University of Forestry and TechnologyChangsha 410004China Key Laboratory of Tropical Atmosphere-Ocean System(Sun Yat-sen University) Ministry of EducationZhuhai 519000China

This study investigates the unsteady natural convection and entropy generation under the effects of magnetic field and baffles inside a nanofluid filled E-shaped *** nanofluid flow is driven by time-varying sidewall temperature and is partitioned by *** factors are discussed,including the enclosure aspect ratio(0.2≤AR≤0.7),nanofluid volume fractions(0≤φ≤0.1),Hartmann numbers(0≤Ha≤80),frequency of time-varying side wall temperature(0.01≤ω≤0.1),baffle locations(0≤d≤0.4)and length(0≤l≤0.4).An economic analysis is conducted to show the nanofluid cost of enhancing thermal transfer and reducing entropy *** modelling results show that increasing aspect ratio and nanofluid volume fraction enhance the thermal transfer behavior,while the magnetic field suppresses the nanofluid natural *** entropy generation monotonically decreases with the increasing nanofluid volume fraction and Hartmann *** baffles into horizontal walls can boost the thermal transfer behavior and decrease the total entropy generation.

关键词： Conjugated heat transfer Economic analysis Entropy generation Time-varying sidewall temperature Magneticﬁeld

Comparison of cytokine levels in prostatic secretion between the Ⅲa and Ⅲb subtypes of prostatitis

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Asian Journal of Andrology 2024年第1期26卷 77-84页

作者： Cheng-Lin Han Yu-Xuan Deng Peng hu Bin-tao hu tao Wang Ji-Hong Liu Ming-Chao Li Department of Urology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000China

Chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS),also known as National Institutes of Health(NIH)type Ⅲ prostatitis,is a common disorder with an unclear etiology and no known curative *** on the presence or absence of leukocytes in expressed prostatic secretion(EPS),CP/CPPS is classifiedfurther into Illa(inflammatory)and Illb(noninflammatory)***,the severity of symptoms is not entirely consistent with the white blood cell(WBC)*** the preliminary finding of a link between inflammatory cytokines and CP/CPPS,we performed this clinical study with the aim of identifying cytokines that are differentially expressed according to whether the prostatitis subtype is Ⅲa or Ⅲ*** found that granulocyte colony-stimulating factor(G-CSF),interleukin-18(IL-18),and monocyte chemoattractant protein-1(MCP-1)levels were significantly elevated and interferon-inducible protein-10(IP-10)and platelet-derived growth factor-BB(PDGF-BB)levels were downregulated in the EPS of patients with type Ⅲa *** a word,it is a meaningful study in which we investigate the levels of various cytokines in EPS according to whether prostatitis is the Ⅲa or Ⅲb *** combination of G-CSF,IL-18,MCP-1,IP-10,and PDGF-BB expression levels could form a basis for classification,diagnosis,and therapeutic targets in clinical P/CPPS.

关键词： chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS) cytokines NIH-Ⅲa NIH-ⅢB

Impact of next-generation sequencing on antimicrobial treatment in immunocompromised adults with suspected infections

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World Journal of Emergency Medicine 2024年第2期15卷 105-110页

作者： Jia Li Jiazhen Luo tao hu Ling Cheng Weiwei Shang Li Yan Department of Intensive Care Unit Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Emergency Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Tongji Medical College Huazhong University of Science and TechnologyWuhan 430030China Department of Geriatrics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

BACKGROUND:Prompt pathogen identification can have a substantial impact on the optimization of antimicrobial *** objective of the study was to assess the diagnostic value of next-generation sequencing(NGS)for identifying pathogen and its clinical impact on antimicrobial intervention in immunocompromised patients with suspected ***:This was a retrospective *** January and August 2020,47 adult immunocompromised patients underwent NGS testing under the following clinical conditions:1)prolonged fever and negative conventional cultures;2)new-onset fever despite empiric antimicrobial treatment;and 3)afebrile with suspected infections on *** data,including conventional microbial test results and antimicrobial treatment before and after NGS,were *** were analyzed according to documented changes in antimicrobial treatment(escalated,no change,or deescalated)after the NGS ***:The median time from hospitalization to NGS sampling was 19 *** relevant pathogens were detected via NGS in 61.7% of patients(29/47),more than half of whom suffered from fungemia(n=17),resulting in an antimicrobial escalation in 53.2% of patients(25/47)and antimicrobial de-escalation in 0.2% of patients(1/47).Antimicrobial changes were mostly due to the identification of fastidious organisms such as Legionella,Pneumocystis jirovecii,and *** the remaining three cases,NGS detected clinically relevant pathogens also detected by conventional cultures a few days *** antimicrobial treatment was subsequently adjusted according to the susceptibility test ***,NGS changed antimicrobial management in 55.3%(26/47)of patients,and conventional culture detected clinically relevant pathogens in 14.9% of the patients(7/47).CONCLUSION:With its rapid identification and high sensitivity,NGS could be a promising tool for identifying relevant pathogens and enabling rapid appropriate treatment in immunocompromised patients w

关键词： Immunocompromised patients Next-generation sequencing Antimicrobial management

Two viral proteins translated from one open reading frame target different layers of plant defense

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Plant Communications 2024年第4期5卷 177-193页

作者： Yuzhen Mei tao hu Yaqin Wang Rosa Lozano-Duran Xiuling Yang Xueping Zhou State Key Laboratory of Rice Biology Institute of BiotechnologyZhejiang UniversityHangzhouZhejiang 310058China State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Department of Plant Biochemistry Center for Plant Molecular Biology(ZMBP)Eberhard Karls University72076 TubingenGermany

Multilayered defense responses are activated upon pathogen *** utilize a number of strategies to maximize the coding capacity of their small genomes and produce viral proteins for infection,including suppression of host ***,we reveal translation leakage as one of these strategies:two viral effec-tors encoded by tomato golden mosaic virus,chloroplast-localized C4(cC4)and membrane-associated C4(mC4),are translated from two in-frame start codons and function cooperatively to suppress ***4 localizes in chloroplasts,to which it recruits NbPUB4 to induce ubiquitination of the outer membrane;as a result,this organelle is degraded,and chloroplast-mediated defenses are ***,chloroplast-localized cC4 induces the production of singlet oxygen(1O2),which in turn promotes translo-cation of the 1O2 sensor NbMBS1 from the cytosol to the nucleus,where it activates expression of the CERK1 ***,an antiviral effect exerted by CERK1 is countered by mC4,localized at the plasma ***4,like cC4,recruits NbPUB4 and promotes the ubiquitination and subsequent degradation of CERK1,suppressing membrane-based,receptor-like kinase-dependent ***,this translation leakage strategy seems to be conserved in multiple viral species and is related to host *** suggests that stacking of different cellular antiviral responses could be an effective way to abrogate viral infection and engineer sustainable resistance to major crop viral diseases in thefield.

关键词： geminivirus C4 PUB4 CERK1 subcellular localization antiviral defense

Adjusting oxygen vacancy of VO_(2)·xH_(2)O nanoarray architectures for efficient NH_(4)^(+) storage

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Nano Research 2024年第4期17卷 2646-2654页

作者： Jia’ni Gong Pengfei Bai Jingjing Sun Yanyan Liu Xueying Dong tao hu Changgong Meng Yifu Zhang School of Chemistry Dalian University of TechnologyDalian 116024China School of Chemistry and Materials Sciences CAS Key Laboratory of Materials for Energy ConversionCAS Center for Excellence in NanoscienceUniversity of Science and Technology of ChinaHefei 230026China College of Environmental and Chemical Engineering Dalian UniversityDalian 116622China

Aqueous rechargeable batteries are the promising energy storge technology due to their safety,low cost,and environmental *** ion(NH_(4)^(+))is an ideal charge carrier for such batteries because of its small hydration radius and low molar *** this study,VO_(2)·xH_(2)O with rich oxygen defects(d-HVO)is designed and synthesized,and it exhibits unique nanoarray structure and good electrochemical performances for NH_(4)^(+)*** and calculation results indicate that oxygen defects in d-HVO can enhance the conductivity and diffusion rate of NH_(4)^(+),leading to improved electrochemical *** most significant improvement is observed in d-HVO with 2 mmol thiourea(d-HVO-2)(220 mAh·g^(-1) at 0.1 A·g^(-1)),which has a moderate defect content.A full cell is assembled using d-HVO-2 as the anode and polyaniline(PANI)as the cathode,which shows excellent cycling stability with a capacity retention rate of 80%after 1000 cycles and outstanding power density up to 4540 W·kg^(-1).Moreover,the flexible d-HVO-2||PANI battery,based on quasi-solid electrolyte,shows excellent flexibility under different bending *** study provides a new approach for designing and developing high-performance NH_(4)^(+)storage electrode materials.

关键词： hydrate vanadium dioxide oxygen defects ammonium-ion battery anode material

Progress and prospects of graphene-based materials in lithium batteries

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Rare Metals 2024年第5期43卷 1886-1905页

作者： Shen Lai tao huang Pei Liu Hong-Bin Wang Shi-Chun Yang Xin-hua Liu Kai Yang Qian-Ling Zhang Jian-Hong Liu Jiang-tao hu Graphene Composite Research Center College of Chemistry and Environmental EngineeringShenzhen UniversityShenzhen 518060China College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen 518060China Shenzhen Eigen-Equation Graphene Technology Co.Ltd Shenzhen518060China School of Transportation Science and Engineering Beihang UniversityBeijing 100191China Department of Electrical and Electronic Engineering Advanced Technology InstituteUniversity of SurreyGuildfordSurrey GU27XHUK

Reasonable design and applications of graphene-based materials are supposed to be promising ways to tackle many fundamental problems emerging in lithium batteries,including suppression of electrode/electrolyte side reactions,stabilization of electrode architecture,and improvement of conductive ***,extensive fundamental research on this aspect has been performed so ***,when it comes to large-scale industrial applications,the utilization of graphene-based materials progresses at a very slow ***,there presents a severe technological decoupling between academic research and industrial application,and there is an urgent need to link ***,in order to address current issues of graphene-based materials used in lithium batteries,we present their latest advancements with stateof-the-art *** applications of graphenebased materials in practical lithium batteries are highlighted and predicted to bridge the gap between the academic progress and industrial manufacture,thereby paving the way for accelerating the development of graphenebased material as well as lithium battery industry.

关键词： Lithium batteries Graphene-based materials Academic research Industrial application Development direction

Comparison of bulk snow density measurements using different methods

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Advances in Climate Change Research 2024年第4期15卷 658-668页

作者： Hang SU Xin-Yue ZHONG Bin CAO Yuan-tao hu Lei ZHENG Tingjun ZHANG State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhan 430072China Key Laboratory of Remote Sensing of Gansu Province Heihe Remote Sensing Experimental Research StationNorthwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China Key Laboratory of Tibetan Plateau Earth System Environment and ResourcesNational Tibetan Plateau Data CenterInstitute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China Climate Centre of Shaanxi Province Xi'an71000China School of Geospatial Engineering and Science Sun Yat-sen University and Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Key Laboratory of Westem China's Environmental Systems(Ministry of Education).College of Earth and Environmental Sciences Lanzhou Universiny Lanzhou 730000China

Snow density is one of the basic properties used to describe snow cover characteristics,and it is critical for remote sensing retrieval,water resources assessment and modeling *** are many instruments available to measure snow density in ***,there are mea-surement errors of snow density for bulk and layers or gravimetric and electronic instruments,which may affect the accuracy of remote sensing retrieval and model *** in China,due to the noticeable heterogeneity of snowpacks,it is necessary to evaluate in detail the performance and applicability of snow density instruments in different snowpack *** study evaluated the performance of different snow density instruments:the Federal Sampler,the model VS-43 snow density cylinder(VS-43),the wedge snow density cutter(WC1000 and WC25O),and the Snow *** average bulk snow density of all instrument measurements was set as the reference value for *** results showed that as compared with the reference,the VS-43 cylinder presented the best performance for bulk snow density measurement in the measured range with the lowest RMSE(11 kg m-3),BIAS(3 kg m-3),and MRE(1.6%).For layer observation,bulk snow density was overestimated by 8.1%with WC1000 and underestimated by 11.4%with Snow Fork which was the worst performance compared with the reference value,and there were greater measurement errors of snow density in the depth hoar than other snow *** with grassland,the uncertainty of snow density measurements was slightly lower in ***,the Federal Sampler and VS-43 cylinder are more suitable for bulk snow density measurement in deep snowpack regions across China,and it is recommended to use WC1000,WC250 and Snow Fork to measure the snow density of snow layers in the snow stratigraphy.

关键词： Snowdensity Measurement Uncertainty comparison

A Novel Accurate Method forMulti-Term Time-Fractional Nonlinear Diffusion Equations in Arbitrary Domains

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1521-1548页

作者： tao hu Cheng huang Sergiy Reutskiy Jun Lu Ji Lin Ningbo Yongxin Engineering Consulting Co. Ltd.Ningbo315042China Taizhou huanfengWater Conservancy Engineering Co. Ltd.Taizhou318050China A.Pidhornyi Institute of Mechanical Engineering Problems National Academy of Sciences of UkraineKharkiv61046Ukraine Material and Structure Department Nanjing Hydraulic Research InstituteNanjing210029China College of Mechanics and Materials Hohai UniversityNanjing211100China

Anovel accuratemethod is proposed to solve a broad variety of linear and nonlinear(1+1)-dimensional and(2+1)-dimensional multi-term time-fractional partial differential equations with spatial operators of anisotropic ***(1+1)-dimensional problems,analytical solutions that satisfy the boundary requirements are *** solutions are numerically calculated using the trigonometric basis approximation for(2+1)-dimensional *** the aid of these analytical or numerical approximations,the original problems can be converted into the fractional ordinary differential equations,and solutions to the fractional ordinary differential equations are approximated by modified radial basis functions with time-dependent *** efficient backward substitution strategy that was previously provided for a single fractional ordinary differential equation is then used to solve the corresponding *** straightforward quasilinearization technique is applied to handle nonlinear *** experiments demonstrate the suggested algorithm’s superior accuracy and efficiency.

关键词： Müntz polynomial basis backward substitutionmethod collocationmethod meshlessmethod fractional equation

A review of structure-activity relationship， enzymatic and genetic modulation of exopolysaccharides from lactic acid bacteria

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Food Science and human Wellness 2024年

作者： Jingyan Zhang tao hu Qingshen Sun Engineering Research Center of Agricultural Microbiology Technology， Ministry of Education & Heilongjiang Provincial Key Laboratory of Plant Genetic Engineering and Biological Fermentation Engineering for Cold Region & Key Laboratory of Microbiology， College of Heilongjiang Province & School of Life Sciences， Heilongjiang University

Lactic acid bacteria (LAB) exopolysaccharides (EPS) reveal high safety and multiple activities， and are typical postbiotics produced by LAB during fermentation. In this paper， 6583 articles on LAB-EPS from web of science and ELSEVIER databases were retrieved， and 236 articles related to this review were screened. The EPS from 90 LAB strains were summarized in terms of their extraction methods， yield， molecular weight， monosaccharide composition， glycosidic bond configuration and the structural and activity relationships (SARs). However， there exist great challenges as for the low yield and high cost in EPS production. Therefore， this review further elaborated the mechanism of EPS secretion， the anabolic pathway of EPS， the structure and mechanism of key enzymes involving in EPS synthesis process， the prospect of gene regulation for EPS secretion， and proposed the engineering strategies for increasing EPS yield or tailored EPS design in recent years. In addition， CRISPR/Cas9 gene editing technology was also discussed in the production control of EPS in LAB. Finally， the engineering strategy of increasing EPS yield in recent years was proposed. This work might provide important theoretical support for the production and application of LAB-based EPS.

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