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Fusing multi-source data to map spatio-temporal dynamics of winter rape on the Jianghan Plain and Dongting Lake Plain, China

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Journal of Integrative Agriculture 2019年第10期18卷 2393-2407页

作者： TAO Jian-bin LIU wen-bin tan wen-xia KONG xiang-bing XU Meng Key Laboratory for Geographical Process Analysis & Simulation of Hubei Province/School of Urban and Environmental Sciences Central China Normal UniversityWuhan 430079P.R.China Key Laboratory of the Loess Plateau Soil Erosion and Water Loss Process and Control Ministry of Water Resources/Yellow River Institute of Hydraulic ResearchZhengzhou 450003P.R.China

Mapping crop distribution with remote sensing data is of great importance for agricultural production, food security and agricultural sustainability. Winter rape is an important oil crop, which plays an important role in the cooking oil market of China. The Jianghan Plain and Dongting Lake Plain (JPDLP) are major agricultural production areas in China. Essential changes in winter rape distribution have taken place in this area during the 21st century. However, the pattern of these changes remains unknown. In this study, the spatial and temporal dynamics of winter rape from 2000 to 2017 on the JPDLP were analyzed. An artificial neural network (ANN)-based classification method was proposed to map fractional winter rape distribution by fusing moderate resolution imaging spectrometer (MODIS) data and high-resolution imagery. The results are as follows:(1) The total winter rape acreages on the JPDLP dropped significantly, especially on the Jianghan Plain with a decline of about 45% during 2000 and 2017.(2) The winter rape abundance keeps changing with about 20–30% croplands changing their abundance drastically in every two consecutive observation years.(3) The winter rape has obvious regional differentiation for the trend of its change at the county level, and the decreasing trend was observed more strongly in the traditionally dominant agricultural counties.

关键词： winter rape,spatio-temporal dynamics,time-series MODIS data artificial neural network

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塞来西布对食管癌ECA-109细胞系放射增敏效应的研究

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中国临床药理学与治疗学 2009年第10期14卷 1095-1100页

作者：王朝霞陈意红谈文霞胡琴吉兆宁皖南医学院附属弋矶山医院放疗科皖南医学院附属弋矶山医院肿瘤内科

目的:了解环氧化物酶-2(COX-2)选择性抑制剂——塞来西布对食管癌ECA-109细胞系的放射增敏作用。方法:选择ECA-109细胞系作为试验对象,检测ECA-109细胞系的COX-2表达水平,设塞来西布0.25、50、100μmol/L4个实验组,分别予6MV-X线照射0、... 详细信息

目的:了解环氧化物酶-2(COX-2)选择性抑制剂——塞来西布对食管癌ECA-109细胞系的放射增敏作用。方法:选择ECA-109细胞系作为试验对象,检测ECA-109细胞系的COX-2表达水平,设塞来西布0.25、50、100μmol/L4个实验组,分别予6MV-X线照射0、2、4、6Gy后,再分别行MTT比色试验、克隆形成实验、流式细胞仪计数,检测细胞的增殖能力、克隆形成能力及凋亡3项指标。结果:不同辐射剂量与不同浓度的塞来西布对ECA-109细胞的增殖、凋亡率作用有统计学差异(P<0.05),塞来西布与放射对ECA-109细胞的增殖抑制和诱导凋亡作用随塞来西布的浓度和照射剂量的增加而增强;塞来西布联合放射对ECA-109细胞的存活率、D0值和Dq值作用均小于单纯放射组,Dq变小;塞来西布和4Gy(6MV-X)联合用于ECA-109细胞其凋亡率有统计学差异(P<0.05)。结论:塞来西布能抑制ECA-109细胞增殖,诱导其凋亡。塞来西布与放射联合应用对ECA-109细胞的增殖抑制、诱导凋亡有协同增强的作用。

关键词：食管肿瘤塞来西布 ECA109细胞系放射增敏凋亡

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Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li wen‑xia Su Jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

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麦芽炒制过程中近红外在线监测模型的建立及“炒香”终点判断研究

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中国中药杂志 2017年第3期42卷 478-485页

作者：杨华生吴维刚谭丽霞闻丽珍王希霖江亭吴璐江西中医药大学江西南昌330004

炒麦芽一直沿用"炒黄炒香"的入药传统,而"炒黄炒香"终点的判断一直是炒制研究的重点与难点。该实验建立指标成分与NIRS之间的定量校正模型用于快速检测总还原糖、总氨基酸、总黄酮、A_(420)及含水量,并提出基于"成分变化率"的炒制终点... 详细信息

炒麦芽一直沿用"炒黄炒香"的入药传统,而"炒黄炒香"终点的判断一直是炒制研究的重点与难点。该实验建立指标成分与NIRS之间的定量校正模型用于快速检测总还原糖、总氨基酸、总黄酮、A_(420)及含水量,并提出基于"成分变化率"的炒制终点判断方法。以近红外光谱仪采集不同炒制时间样品光谱,建立基于近红外光谱的定量分析模型,并对光谱预处理、建模波段等参数进行优选;采用HCA,PLS-DA研究成分与"炒香"的关系,确定炒制终点。所建立的校正模型性能良好,采用所建模型进行在线分析,预测结果与实际测定值相关系数均大于0.9,预测相对偏差小于10%;HCA方法将在不同炒制时间的麦芽分为4类,PLS-DA分析表明总还原糖对区分不同炒制时间的麦芽具有显著的贡献率,当总还原糖的变化率为80%时,即可判断"炒香"终点的到达。结果表明,近红外光谱可快速准确地测定麦芽不同炒制时间样品中总还原糖、总氨基酸、总黄酮、A_(420)及含水量,并可判断"炒香"工艺终点,为中药炒制工艺的评价及终点判断提供新的研究方法。

关键词：近红外光谱麦芽炒制过程在线监测终点判断

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Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang Ni-Hui Zhang Zhi-Lai Zhan Guang-Lu Chang Yan Gao xia Li wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

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3D Crystal Plasticity Finite Element Modeling of the Tensile Deformation of Polycrystalline Ferritic Stainless Steel

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Acta Metallurgica Sinica(English Letters) 2017年第1期30卷 79-88页

作者： Chi Zhang Li-wen Zhang wen-Fei Shen Ying-Nan xia Yu-tan Yan School of Materials Science and Engineering Dalian University of TechnologyDalian 116024China

A mesoscale model of plastic deformation of ferritic stainless steels （FSSs） is formulated by combining a crystal plasticity finite element model with 3D cellular automaton algorithm. The actual grain orientations of FSS cold rolling and annealing sheet have been detected by electron backscatter diffraction and selected to be assigned to the polycrystal model. The simulation results have been validated by comparing the calculated true stress-strain response with the experimental one. For the lack of considering the interactions of dislocations with impurities, there are no upper and lower yield points in the simulation stress-strain curves. However, the calculated yield strength and the stress-strain response after yielding agree well with the real material. The local stress and strain fields show inhomogeneous at mesoscale. The plastic deformations of the grains with typical orientations have been characterized. The analysis reveals that the grains with fiber texture show higher thickness reduction ratio as compared to others. The deformation behaviors of the grains in polycrystal are not only related to the orientations but also to the interactions from adjacent grains.

关键词： Ferritic steels Crystallographic orientation Polycrystal plasticity modeling Cellular automaton

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Bioengineered pseudovirus nanoparticles displaying the HA1 antigens of influenza viruses for enhanced immunogenicity

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Nano Research 2022年第5期15卷 4181-4190页

作者： Ming xia Md Rejaul Hoq Pengwei Huang wen Jiang Xi Jiang Ming tan Division of Infectious Diseases Cincinnati Children’s Hospital Medical CenterCincinnatiOH 45229USA Department of Biological Sciences Purdue Cryo-EM FacilityPurdue UniversityIN 47907USA Department of Pediatrics University of Cincinnati College of MedicineCincinnatiOH 45229USA

Even with implementation of current influenza vaccines,influenza still claims up to 500,000 lives worldwide annually,indicating a need for a better vaccine *** have developed a technology to generate unique S_(60)-HA1 pseudovirus nanoparticles(PVNPs)that display the receptor-binding HA1 domains of influenza *** self-assembled S_(60)-HA1 PVNP consists of a T=1 icosahedral S_(60) nanoparticle that resembles the inner shell of norovirus capsid and 60 surface-displayed HA1 antigens that are excellent vaccine *** S_(60)-HA1 PVNPs presenting HA1 antigens of H7N9 influenza virus subtypes have been produced efficiently in large *** three-dimensional(3D)structures have been solved by cryogenic electron *** PVNP-displayed HA1 antigens react with HA-specific antibody,and retain authentic sialic acid binding specificity and hemagglutinate human *** PVNPs are highly immunogenic,eliciting high titers of HA1-specific antibodies in mice and the mouse sera strongly inhibited hemagglutinations of homologous and heterologous influenza virus HA ***,the S_(60)-HA1 PVNPs may provide useful reagents to study influenza viruses and offer a potential new vaccine tactic to fight the deadly influenza disease.

关键词： S_(60)nanoparticle pseudovirus nanoparticle influenza virus influenza vaccine hemagglutinin norovirus

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宫颈恶性肿瘤根治术后淋巴囊肿的临床观察与护理

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中国医药 2013年第6期8卷 857-858页

作者：张红玲钟序素谢素娟谭文霞蒲海兰第三军医大学第二附属医院妇产科重庆400030

目的探讨宫颈恶性肿瘤根治术后淋巴囊肿的临床观察与护理，探讨其预防措施。方法2009年3月至2011年12月期间施行子宫颈癌根治术96例，其中宫颈鳞状上皮细胞癌43例，宫颈中分化腺癌20例，宫颈腺鳞癌26例，宫颈透明细胞癌4例，宫颈肉瘤3... 详细信息

目的探讨宫颈恶性肿瘤根治术后淋巴囊肿的临床观察与护理，探讨其预防措施。方法2009年3月至2011年12月期间施行子宫颈癌根治术96例，其中宫颈鳞状上皮细胞癌43例，宫颈中分化腺癌20例，宫颈腺鳞癌26例，宫颈透明细胞癌4例，宫颈肉瘤3例。临床分期：Ia期21例，Ib期26例，Ⅱa期32例，Ⅱb期17例。结果本组29例淋巴囊肿，经密切观察，囊肿在10d左右消失。有3例出现巨大囊肿，经淋巴囊肿穿刺引流，患者痊愈出院。结论宫颈恶性肿瘤根治术后淋巴囊肿的成因以及术中预防可降低术后发病率。

关键词：宫颈癌淋巴囊肿静脉血栓护理

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Induction of apoptosis in human liver carcinoma HepG2 cell line by 5-allyl-7-gen-difluoromethylenechrysin

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World Journal of Gastroenterology 2009年第18期15卷 2234-2239页

作者： xiang-wen tan Hong xia Jin-Hua Xu Jian-Guo Cao Department of Laboratory Animal Science University of South China Hengyang 421001 Hunan ProvinceChina Institute of Cancer Research University of South China Hengyang 421001 Htman Province China Center of Biochemistry and Molecular Biology Laboratory University of South China Hengyang 421001Hunan Province China Laboratory of Medicine Engineering Medical College Hunan Normal University Changsha 410006 Hunan Province China

AIM： To investigate the effect of 5-allyl-7-gen-difluoromethylenechrysin （ADFMChR） on apoptosis of human liver carcinoma HepG2 cell line and the molecular mechanisms ***： HepG2 cells and L-02 cells were cultured in vitro and the inhibitory effect of ADFMChR on their proliferation was measured by MTT assay. The apoptosis of HepG2 cells was determined by flow cytometry （FCM） using propidium iodide （PI） fluorescence staining. DNA ladder bands were observed by DNA agarose gel electrophoresis. The influence of ADFMChR on the proxisome proliferator-activated receptor γ （PPARγ）, NF-κB, Bcl-2 and Bax protein expression of HepG2 cells were analyzed by Western ***： MTT assay showed that ADFMChR significantly inhibited proliferation of HepG2 cells in a dose- dependent manner, with little effect on growth of L-02 cells, and when ICs0 was measured as 8.45 μmol/L and 191.55 μmol/L respectively, the potency of ADFMChR to HepG2 cells, was found to be similar to 5-fluorouracil （5-FU, ICso was 9.27 μmol/L）. The selective index of ADFMChR cytotoxicity to HepG2 cells was 22.67 （191.55/8.45）, higher than 5-FU （SI was 7.05 （65.37/9.27）. FCM with PI staining demonstrated that the apoptosis rates of HepG2 cells treated with 3.0, 10.0 and 30.0 μmol/L ADFMChR for 48 h were 5.79%, 9.29% and 37.8%, respectively, and were significantly higher when treated with 30.0 μmol/L ADFMChR than when treated with 30.0 μmol/L ChR （16.0%）（P 〈 0.05） and were similar to those obtained with 30.0 μmol/L 5-FU（41.0%）. DNA agarose gel electrophoresis showed that treatment of HepG2 cells with 10.0 μmol/L ADFMChR for 48 h and 72 h resulted in typical DNA ladders which could be reversed by 10.00 pmol/1 GW9662, a blocker of PPARy. Western blotting analysis revealed that aEer 24 h of treatment with 3.0, 10.0, 30.0 μmol/L ADFMChR, PPARy and Bax protein expression in HepG2 cells increased but Bcl-2 and NF-κB expression decreased; however, pre-incubation with 10.0 μmol/L GW9662 could efficiently

关键词： Liver neoplasm Chrysin 5-allyl-7-gen-difluoromethylenechrysin Apoptosis Proxisome prolif-erator-activated receptor γ

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Identification of quantitative trait loci and candidate genes associated with ABA sensitivity in common wild rice (Oryza rufipogon Griff,)

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Journal of Integrative Agriculture 2017年第11期16卷 2375-2385页

作者： CAI wen-yang tan Lu-bin LIU Feng-xia SUN Chuan-qing National Center for Evaluation of Agricultural Wild Plants (Rice)/Beijing Key Laboratory of Crop Genetic Improvement/Departmentof Plant Genetics and Breeding China Agricultural University Beijing 100193 P.R. China

Abscisic acid （ABA）, as one of the foremost signaling molecules in plants, is an important hormone which plays versatile functions in regulating developmental process and adaptive stress process. A set of introgression lines were previously generated via a backcrossing program using an elite indica cultivar rice Teqing （O. sativa L.） as recipient and an accession of Yuanjiang common wild rice （O. rufipogon Griff.） as donor. In this study, the previously developed introgression lines were evaluated for ABA sensitivity. Here we reported that a total of 14 quantitative trait loci （QTLs） associated with ABA sensitivity were identified. An ABA sensitive introgression line, YIL53, was identified and characterized. Physiological characterization, including chlorophyll content, malondialdehyde content, soluble sugar content, and stomata movement, demonstrated that YIL53 exhibited the characteristics associated with ABA sensitivity. Genotypic analysis revealed that YIL53 harbored one QTL related to ABA sensitivity, qASS1-2, which was located on chromosome 1 within one introgressed segment derived from the Yuanjiang common wild rice. Furthermore, the qASS1-2 was finally narrowed down to a 441-kb region between simple sequence repeats （SSR） marker RM212 and single nucleotide polymorphism （SNP） marker M3 using the segregation population derived from the cross between Teqing and YIL53, and three candidate genes associated with ABA sensitivity were identified using a strategy combined gene expression analysis with QTL mapping. Identification of the QTLs related to ABA sensitivity and characterization of the ABA sensitive line YIL53 would provide a helpful basis for isolating novel genes related to ABA sensitivity.

关键词： wild rice introgression lines ABA sensitivity quantitative trait locus candidate gene

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