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Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang Zeng wei tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen Zhen wei Yufei Mei Yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

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Aerodynamic Optimization and Flow Mechanism for a Compressor Cascade at Low Reynolds Number

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Journal of Thermal Science 2025年第1期 92-109页

作者： LI Lin ZHANG Jianshe CHEN Caiyan tan wei ZHANG Yanfeng Key Laboratory of Light-Duty Gas-Turbine Institute of Engineering ThermophysicsChinese Academy of Sciences University of Chinese Academy of Sciences National Key Laboratory of Science and Technology on Advanced Light-duty Gas-turbine

Low-Reynolds-number effect is an important factor affecting the performance of compressors and other main components of high-altitude long-endurance unmanned aerial *** improve the flow condition and reduce flow loss under the condition of high altitude and low Reynolds number(Re),this paper proposes an optimization process based on a surrogate model,which combines the class-shape transformation method(CST),the Latin hypercube sampling(LHS) method,the light gradient-boosting machine algorithm(LightGBM),and a genetic algorithm(GA) to optimize a high-subsonic compressor *** surrogate model is verified to be accurate and can be used in the optimization *** accuracy of the GA is higher than the other algorithms under common test *** optimization results are verified by numerical simulation,and the flow differences before and after optimization are compared,especially the flow within the boundary *** changing the blade shape,the optimization process adjusts the loading distribution to delay the transition of the optimized blade on the suction surface,which changes the turbulent reattachment in the laminar separation bubble(LSB) into laminar ***,the mixing loss induced by the turbulent reattachment of the LSB and the wake loss of turbulent separation at the trailing edge are significantly reduced,and the performance of the compressor profile is finally *** addition,turbulent separation of the optimized profile is delayed reducing the range of the wake region on the suction *** this optimization process,the reduction of total pressure loss coefficient at Re of 2.5×10～5,3.5×10～5,and 4.5×10～5 are 16.32%,20.76%,and 22.16%,respectively.

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Application of Forearm FMG signals in Closed Loop Modality-matched Sensory Feedback Stimulation

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Journal of Bionic Engineering 2020年第5期17卷 899-908页

作者： Jing wei tan Yimesker Yihun Department of Mechanical Engineering Wichita State UniversityWichitaKansas 67260USA

This study is aimed at exploring a technology that can use the human physiological information,such as Force Myography(FMG)signals to provide sensory feedback to prosthetic hand *** is based on the principle that with the intent to move the prosthetic hand,the existing limbs in the arm recruit specific group of *** muscles react with a change in the cross-sectional area;piezoelectric sensors placed on these muscles will generate a voltage(FMG signals),in response to the change in muscle *** correlation between the amplitude of the FMG signals and intensity of pressure on fingertips during grasping is then computed and a dynamic relation(model)is established through system identification in *** estimated models generated a fitting accuracy of more than 80%.The model is then programmed into the Arduino microcontroller,so that a real-time and proportional force feedback is channeled to amputees through a micro *** such percentages of accuracy in sensory feedback without relying on touch sensors on the prosthetic hand that could be affected by mechanical wear and other interaction factors is *** advanced signal processing and classification techniques may also refine the findings to better capture and correlate the force variations with the sensory feedback.

关键词： FMG sensory feedback prosthetic hand bionic robot modality-matched sensory stimulation

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“Relay-mode”promoting permeation of water-based fire extinguishing agent in granular materials porous media stacks

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Chinese Journal of Chemical Engineering 2022年第7期35卷 98-112页

作者： Kang Wang wei tan Liyan Liu School of Chemical Engineering and Technology Tianjin UniversityTianjin 300350China Tianjin Key Laboratory of Chemical Process Safety and Equipment Technology Tianjin 300350China

Water-based fire extinguishing agent is the main means to deal with smoldering ***,due to the hydrophobic properties of the particle surface,the porous medium channel provide resistance and slow down the extinguishing agent flow during the downward permeation *** promote the liquid permeation process in such porous media,this work studied liquid imbibition process and analyzed the oscillating and attenuating process of liquid level in capillary channel by theoretical,experimental,and numerical *** empirical mathematical equation was proposed to describe the oscillating process,and the effects of the capillary diameter and contact angle parameters on the transportation process were *** on this,the“relay-mode”was proposed to promote the liquid transportation ***,the transient simulation results of liquid permeation in coal stacks showed when the liquid flowed through the channel with changed diameter from large to small ones,the transportation distance was several times longer than that through the unidiameter *** trend of liquid“relay-mode”in capillaries can be used to promote the permeation in granular materials porous media *** relevant results also provide new thoughts to develop the water-based fire extinguishing agents and then improve the firefighting efficiency of deep-seated fire in porous media stacks.

关键词： Granular materials Porous media Safety Permeation Water-based fire extinguishing agent

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Damped Jaynes-Cummings Model Including Spontaneous Emission

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Chinese Physics Letters 2001年第2期18卷 220-222页

作者： tan wei-Han Department of Physics Shanghai UniversityShanghai 201800

As a continuation of the previous paper‘Collapse and revival in the damped Jaynes-Cummings model’[***.16(1999)895],at present the problem is solved under the condition that the atomic spontaneous emission is *** the case of no damping,c=0,γ_(1)≠0,γ_(2)≠0,the half atomic inversion operatorpossesses an analytic solution,whereas in the general case c≠0,the problem is reduced to the numerical evaluation of first-order nonlinear differential *** final results show that with the increase ofγ_(1) andγ_(2),the kinetic quantities converge rapidly to stationary solutions.

关键词： equations stationary quantities

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Combining Radon-ambiguity transform with second-order difference to improve detection probability of LFM signals in low SNR

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Journal of Systems Engineering and Electronics 2009年第1期20卷 13-19页

作者： tan Xiaogang wei Ping Li Liping School of Electronic Engineering Univ. of Electronic Science and Technology of China Chengdu 610054 P. R. China

The Radon-ambiguity transform （RAT）, although efficient for detecting the linear frequency modulated signals （LFMs）, is troubled by the energy accumulation of noise in low signal-to-noise ratio （SNR）. A secondorder difference （SOD） method is proposed to treat with this problem. In the SOD method, the optimal search step and difference step are derived from the LFM rate resolution formula. The sharpness of the peaks of RAT is measured by curvature, and the sharpness, but not the magnitude of the peaks, is used to detect the LFMs. The SOD method removes the noise energy accumulation and reserves the drastically changing components integrally; thus, it improves the detection probability of LFMs in low SNR. The expected performance of the new method is verified by 100 Monte Carlo simulations.

关键词： linear frequency modulated signals Radon-axnbiguity transform detection probability low signal-to-noise ratio.

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weighted Variation Inequalities for Singular Integrals and Commutators in Rearrangement Invariant Banach and Quasi-Banach Spaces

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Acta Mathematica Sinica,English Series 2023年第7期39卷 1389-1413页

作者： Jia wei tan Qing Ying XUE School of Mathematical Sciences Beijing Normal UniversityLaboratory of Mathematics and Complex SystemsMinistry of EducationBeijing 100875China

In order to study the boundedness of some operators in general function spaces which include Lorentz spaces and Orlicz spaces as special examples,Lorentz introduced a new space called rearrangement invariant Banach function spaces,denoted by *** is shown in this paper that variation operators of singular integrals and their commutators are bounded on RIBFS whenever the kernels satisfy the L~r-H?rmander ***,we obtain some quantitative weighted bounds in the quasi-Banach spaces and modular inequalities for above variation operators and their commutators.

关键词： Variation operators singular integrals commutators sparse operators rearrangement invariant Banach function spaces

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On the General and Resonant Solutions of Atoms Reflected by an Evanescent Laser Wave

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Chinese Physics Letters 1996年第8期13卷 587-589页

作者： tan wei-han LI Qiang-ning Department of Physics Shanghai UniversityShanghai 200072 and Shanghai Institute of Optics and fine Mechanics Chinese Academy of SciencesShanghai 201800

Usually the reflection of two level atoms by a detuning evanescent laser wave was studied in past few years.1-3 In previous paper we have presented an exact solution for this model based on the matrix Laplace transformation technique,and proceeded the numerical calculations for a given set of parameters.4 However in the special case of resonance interaction considered in this paper,the solution for Schrödinger wave equation and reflectivity calculation can be greatly simplified;besides,the resonant solution provides a check to the numerical data based on the general solution of the previous paper.

关键词： parameters wave simplified

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The distribution,characteristics and fluid sources of lode gold deposits:An overview

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Science China Earth Sciences 2021年第9期64卷 1463-1480页

作者： Christina Yan WANG Bo wei wei tan Zaicong WANG Qingdong ZENG CAS Key Laboratory of Mineralogy and Metallogeny/Guangdong Provincial Key Laboratory of Mineral Physics and Materials Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou510640China CAS Center for Excellence in Deep Earth Science Chinese Academy of SciencesGuangzhou510640China State Key Laboratory of Geological Processes and Mineral Resources(GPMR) School of Earth SciencesChina University of GeosciencesWuhan430074China Key Laboratory of Mineral Resources Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China Institutions of Earth Science Chinese Academy of SciencesBeijing100029China University of Chinese Academy of Sciences Beijing100029China

Lode gold deposits are among the most economically important types of gold deposits in the ***,they formed mainly in three time intervals,2.8 to 2.5 Ga,2.1 to 1.8 Ga,and 700 Ma to the *** of ore-forming fluids and other components are of critical importance in a better understanding of the genesis and the geodynamic controls of these *** ore-forming fluids were mostly derived from devolatization of sedimentary and/or volcanic sequences during greenschist to amphibolite facies metamorphism associated with orogenic deformation,magmatic hydrothermal fluids have been increasingly shown to be important in many gold deposits in various *** this review paper,we summarize the major features of lode gold deposits,possible sources of ore-forming fluids,and mechanisms of gold *** we acknowledge the critical role of metamorphically derived fluids in the genesis of such deposits worldwide,we emphasize that mantle-or basaltic magma-derived fluids may have been much more important than commonly *** use the Liaodong peninsula of the North China Craton as an example to demonstrate the significance of mantle-derived *** earlier studies and new data,we show that some of the late Mesozoic lode gold deposits in the North China Craton may have formed from magmatic hydrothermal fluids due to the extension and partial melting of the hydrated,metasomatized subcontinental lithosphere mantle,as best exemplified by the Wulong gold deposit.

关键词： Lode gold deposit Ore-forming fluid Metasomatized subcontinental lithosphere mantle Mantle-derived melt/fluid North China Craton

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Impacts of close-to-nature management on the stand states of Masson pine forests

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Ecosystem Health and Sustainability 2020年第1期6卷 425-432,424页

作者： Zongzheng Chai wei tan College of Forestry Guizhou UniversityGuiyangGuizhouPR China

Introduction:Research on the effect of close-to-nature management(CTNM)on stand states and dynamics of forests is crucial for the evaluation of CTNM implemented and sustainable development of ***:We analyzed and compared the stand states and dynamics of Masson pine(Pinus massoniana)plantations in the young,middle-aged,and near-mature stages under CTNM eight years after selective cutting and unmanaged *** paired-sample T-tests and RDA ordination results demonstrated that the overall stand states with CTNM were superior to the control treatment in all three *** interaction of the CTNM and stand age significantly affected The Shannon-Wiener index of diameter class and regeneration *** and Conclusion:CTNM and stand age jointly affected the stand state of forests and CTNM accelerated the forest development,which promoted an increase in the heterogeneity of stand parameters and shortened the formation time of a target *** tree size differentiation and adequate regeneration are particularly important aspects for improving the quality of Masson pineforests during the management processes.

关键词： close-to-nature management forest quality stand states development stage

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