检索结果-南通市图书馆

Photodynamic therapy in the treatment of intracranial gliomas:A review of current practice and considerations for future clinical directions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

journal of Innovative Optical Health Sciences 2015年第1期8卷 40-59页

作者： Carl j.fisher Lothar Lilge Department of Medical Biophysics University of Toronto Princess Margaret Cancer Centre 101 College StRm.15-710 TorontoON M5G 1L7 University Health Network Princess Margaret Cancer Centre 101 College St Rm.15-310TorontoON M5G 1L7

Invasive grade III and IV maliguant gliomas remain difficult to treat with a typical survival time post-diagnosis hovering around 16 months with only minor extension thereof seen in the past decade,whereas some improvements have been obtained towards five-year survival rates for which completeness of resection is a *** techniques such as fluorescence guided resection(FGR)and photodynamic therapy(PDT)are promising adjuvant techniques to in-crease the tumor volume reduction *** has been used in combination with surgical resection or alternatively as standalone treat ment strategy with some sucoess in extending the median survival time of patients compared to surgery alone and the current standard of *** document reviews the outcome of past clinical trials and highlights the general shift in PDT therapeutic *** also looks at the current approaches for interstitial PDT and research options into increasing PDT's glioma treatment fficacy through exploiting both physical and biological based approaches to maximize PDT selectivity and therapeutic index,particularly in brain adjacent to tumor(BAT).Potential reasons for failing to demonstrate a significant survival advantage in prior PDT clinical trials will become evident in light of the improved understanding of glioma biology and PDT dosimetry.

关键词： Oncology brain tumour photodynamic dose therapeutic index photofin aminolu-velinic acid

Azoospermia:vasal agenesis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian journal of Andrology 2022年第1期24卷 1-4页

作者： j Sam fisher Edward D Kim Department of Urology University of TennesseeKnoxvilleTN 37920USA

SPECIFIC GENETIC TESTS(CFTR AND INTRON 8 SPLICE VARIANT TESTING)AND THEIR SIGNIFICANCE Congenital bilateral absence of the vas deferens(CBAVD)and cystic fibrosis(CF)began as separate entities with an apparent clinical *** occurs in 1%–2%of men presenting with infertility at urological departments and has an incidence of 1:1000–1:2000 in Caucasian *** example of this anatomic variant is shown in Figure 1.

关键词： correlation. clinical Figure

Development of Monodispersed Polymeric Media for Purification and Analysis of Biomacromolecules

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Development of Monodispersed Polymeric Media for Purificatio...

第十五次全国色谱学术报告会

作者： j.Maikner j.fisher A.Gehris M.Kinzey M.Vanderhoff Rohm and Haas Company. 727 Norristown Rd. Spring HousePA 19477 Rohm and Haas Company. 727 Norristown Rd. Spring HousePA 19477 Rohm and Haas Company. 727 Norristown Rd. Spring HousePA 19477 Rohm and Haas Company. 727 Norristown Rd. Spring HousePA 19477 Rohm and Haas Company. 727 Norristown Rd. Spring HousePA 19477

＜正＞We have developed a novel technology which can be used to prepare highly uniform polymeric microparticles with controlled pore structure and high rigidity. The monodispersed polymeric micorparticles have demonstrated superior performances in column chromatography separation and analysis of biomacromolecules. For example, influenza peptide M1, [H]-Gly-Ile-Leu-Gly-Phe-Val-Phe-Thr-Leu-[OH], is of interest for its utility in the area of vaccine

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

增量调制在广播中的应用

广播与电视技术 1987年第1期 51-55页

作者： G·Carter j.fisher 展望

由于数字声频系统的潜在的透明性和最终信号的高质量,对听众进行高质量信号的数字广播是具有吸引力的。用传统的脉码调制(PCM)法进行信号处理尽管性能良好,但在接收机中需要采用复杂而精确的电路,因此价格昂贵。Dolby实验室已研究出一... 详细信息

由于数字声频系统的潜在的透明性和最终信号的高质量,对听众进行高质量信号的数字广播是具有吸引力的。用传统的脉码调制(PCM)法进行信号处理尽管性能良好,但在接收机中需要采用复杂而精确的电路,因此价格昂贵。Dolby实验室已研究出一种自适应增量调制(ADM)法,采用这种方法,在接收机中使用简单得多的、廉价的译码器就可获得与PCM相当的质量。

关键词：声频系统 ADM 增量调制 △调制译码器解码器广播

Associations of self-reported and device-assessed physical activity with fatigue,quality of life,and sleep quality in adults living with and beyond cancer

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

journal of Sport and Health Science 2023年第6期12卷 664-673,F0003页

作者： Phillippa Lally Natalie Ella Miller Claire Lawrence Rebecca j Beeken Abigail fisher Department of Behavioural Science and Health University College LondonLondon WC1E 6BTUK Department of Psychology University of SurreyGuildford GU27XHUK Leeds Institute of Health Sciences Leeds LS29NLUK

Background Greater physical activity is associated with improved outcomes in people living with and beyond ***,most studies in exercise oncology use self-reported measures of physical *** have explored agreement between self-reported and device-based measures of physical activity in people living with and beyond *** study aimed to describe physical activity in adults affected by cancer across self-reported and device-assessed activity,to explore levels of agreement between these measures in terms of their utility for categorizing participants as meeting/not meeting physical activity guidelines,and to explore whether meeting guidelines is associated with fatigue,quality of life,and sleep *** A total of 1348 adults living with and beyond cancer from the Advancing Survivorship Cancer Outcomes Trial completed a survey assessing fatigue,quality of life,sleep quality,and physical *** Godin-Shephard Leisure-Time Physical Activity Questionnaire was used to calculate a Leisure Score Index(LSI)and an estimate of moderate-to-vigorous physical activity(MVPA).Average daily steps and weekly aerobic steps were derived from pedometers worn by *** The percentage of individuals meeting physical activity guidelines was 44.3%using LSI,49.5%using MVPA,10.8%using average daily steps,and 28.5%using weekly aerobic ***(Cohen'sκ)between self-reported and pedometer measures ranged from 0.13(LSI *** daily steps)to 0.60(LSI ***).After adjusting for sociodemographic and health-related covariates,meeting activity guidelines using all measures was associated with not experiencing severe fatigue(odds ratios(ORs):1.43–1.97).Meeting guidelines using MVPA was associated with no quality-of-life issues(OR=1.53).Meeting guidelines using both self-reported measures were associated with good sleep quality(ORs:1.33–1.40).Conclusion Less than half of all adults affected by cancer are meeting physical activity guidelines,

关键词： Cancer survivorship Fatigue Physical activity Quality of life SleepTagedAPTARAEnd

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

地球的过去和现在

地球的过去和现在

Systems biology approaches for studying the pathogenesis of non-alcoholic fatty liver disease

丛书名：科技英语通俗读物

1965年

作者：（英）费希尔（j.fisher）涂云深注释

本书分为：首先简述宇宙各个星体的概况，重点放在地球的形成；其次讲述日照、降雨、风吹、植物生长等自然现象；最后讲述地球上山、川、湖泊、海洋、气候等对生物的关系等三部分。

ISBN: (纸本)9017·602

关键词：语言、文字常用外国语

来源：汇雅图书（南通市图书馆... 评论

在线全文

汇雅图书（南通市图书馆）

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2014年第41期20卷 15070-15078页

作者： Ciarán P fisher Andrzej M Kierzek Nick j Plant j Bernadette Moore Faculty of Health and Medical Sciences University of Surrey

Non-alcoholic fatty liver disease (NAFLD) is a progressive disease of increasing public health concern. In western populations the disease has an estimated prevalence of 20%-40%, rising to 70%-90% in obese and type II diabetic individuals. Simplistically, NAFLD is the macroscopic accumulation of lipid in the liver, and is viewed as the hepatic manifestation of the metabolic syndrome. However, the molecular mechanisms mediating both the initial development of steatosis and its progression through non-alcoholic steatohepatitis to debilitating and potentially fatal fibrosis and cirrhosis are only partially understood. Despite increased research in this field, the development of non-invasive clinical diagnostic tools and the discovery of novel therapeutic targets has been frustratingly slow. We note that, to date, NAFLD research has been dominated by in vivo experiments in animal models and human clinical studies. Systems biology tools and novel computational simulation techniques allow the study of large-scale metabolic networks and the impact of their dysregulation on health. Here we review current systems biology tools and discuss the benefits to their application to the study of NAFLD. We propose that a systems approach utilising novel in silico modelling and simulation techniques is key to a more comprehensive, better targeted NAFLD research strategy. Such an approach will accelerate the progress of research and vital translation into clinic.

关键词： Non-alcoholic fatty liver disease Network Metabolism Systems biology Modelling Regulation Simulation

Multilayer network analysis:new opportunities and challenges for studying animal social systems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Zoology 2021年第1期67卷 45-48页

作者： Matthew j.HASENjAGER Matthew SILk David N.fisher Department of Biological Sciences Royal HollowayUniversity of LondonEghamUK Centre for Ecology and Conservation University of ExeterExeterUK School of Biological Sciences University of AberdeenAberdeenUK

Introduction Many behavioral,ecological,and evolutionary processes are closely intertwined with patterns of social interactions,such as the evolution of cooperation(Croft et al.2006),information and disease transmission(VanderWaal et al.2014;Aplin et al.2015),predator-prey dynamics(Ioannou et al.2012),and dispersal decisions(Blumstein et al.2009).Even in species where individuals are traditionally viewed as leading a relatively solitary existence,interac-tions occur across diverse contexts,including territorial defense,resource competition,and courtship.

关键词： solitary predator network

Estimation of cotton yield with varied irrigation and nitrogen treatments using aerial multispectral imagery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International journal of Agricultural and Biological Engineering 2013年第2期6卷 37-41页

作者： Yanbo Huang Ruixiu Sui Steven j.Thomson Daniel K.fisher Crop Production Systems Research Unit Agricultural Research ServiceUnited States Department of AgricultureStonevilleMS 38776USA

Cotton yield varies spatially within a *** variability can be caused by various production inputs such as soil properties,water management,and fertilizer *** multispectral imaging is capable of providing data and information to study effects of the inputs on yield qualitatively and quantitatively in a timely and cost-effective fashion.A 10-ha cotton field with irrigation and non-irrigation 2×2 blocks was used in this *** nitrogen application treatments were randomized with two replications within each *** plant canopy was closed,airborne multispectral images of the field were acquired using a 3-CCD MS4100 *** images were processed to generate various vegetation *** vegetation indices were evaluated for the best performance to characterize *** effect of irrigation on vegetation indices was *** for yield estimation were developed and verified by comparing the estimated and actual *** indicated that ratio of vegetation index(RVI)had a close relationship with yield(R^(2)=0.47).Better yield estimation could be obtained using a model with RVI and soil electrical conductivity(EC)measurements of the field as explanatory variables(R^(2)=0.53).This research demonstrates the capability of aerial multispectral remote sensing in estimating cotton yield variation and considering soil properties and nitrogen.

关键词： remote sensing multispectral imagery cotton yield nitrogen irrigation soil properties