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Journal of Geriatric Cardiology 2017年第9期14卷 541-546页

作者： Evgeny N Mikhaylov tamas Szili-Torok Dmitry S Lebedev Arrhythmia Department Almazov National Medical Research Centre Saint-Petersburg Russia Neuromodulation Laboratory Almazov National Medical Research Centre Saint-Petersburg Russia Electrophysiology Unit Cardiology Department Erasmus Medical Center Rotterdam the Netherlands

Heart rhythm disturbances become of special importancewhen patients reach a senior age. Atrial fibrillation （AF） isthe most prevalent arrhythmia among the old age groups,and its impact on morbidity and mortality becomes of para-mount significance. In this population, AF is responsible forsignificant amount of thromboembolic cerebrovascularevents, especially for disabling and fatal strokes, Follow-ing announcement of the special issue of the Journal of Geri-atric Cardiology devoted to heart rhythm disorders in theelderly, a number of submissions have been received withAF as the major topic of authors＇ researches.

关键词： Atrial fibrillation Ablation Efficacy Left atrial appendage Occlusion Safety The elderly

Pulmonary embolization as primary manifestation of hepatocellular carcinoma with intracardiac penetration: A case report

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World Journal of Gastroenterology 2005年第15期11卷 2357-2359页

作者： Elod Papp Zsuzsanna Keszthelyi Nagy Karoly Kalmar Lajos Papp Csaba Weninger tamas Tornoczky Endre Kalman Kalman Toth tamas Habon 1st Department of Medicine Department of Surgery Heart Institute Department of Radiology Department of Pathology

Intracardiac manifestation of hepatocellular carcinoma (HCC) is a rare condition and an uncommon finding even at autopsy. Pulmonary tumor embolism as a presenting feature of HCC has been published only twice previously. In our case report, a 63-year-old man presented with high fever and six episodes of recurrent pneumonias during the last half year. Echocardiography was performed, a solid mass was found in the right atrium. Transesophageal echocardiography proved a tumor mass in the inferior vena cava (IVC) extending into the right atrium, abdominal ultrasound revealed tumor mass in the IVC and a solid tumor in the liver. Combined liver and heart surgery was attempted in order to remove the tumor mass from both the liver and the right atrium. Acute cor pulmonale occurred during tumor removal from the right atrium and the patient expired. In addition to local factors the possibility of embolization should arise in the background of recurrent pneumonia. Occult carcinoma must be included in possible causes of recurrent pulmonary embolism. Searching for primary malignancy should include HCC as frequent cause of hypercoagulability. In case of HCC, echocardiography is suggested because of the possibility of expansion in IVC or right atrium and tumor-embolization.

关键词： Hepatocellular carcinoma Intracardiac penetration Pulmonary embolization

Topographic and lithologic controls behind mountain depopulation in Zlatibor District(Western Serbia)

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Journal of Mountain Science 2020年第2期17卷 271-288页

作者： TELBISZ tamas BRANKOV Jovana CALIC Jelena Department of Physical Geography Eotvos Loránd UniversityBudopestHungary Geographical Institute"Jovan Cvijic"of the Serbian Academy of Sciences and Arts BelgradeSerbia South Ural State University Institute of SportsTourism and Service60Sony Krivoy streetChelyabinsk454080Russia

Mountain depopulation is a worldwide phenomenon observed in all continents. It has varied socio-economic reasons;among others, the low profitability of traditional agriculture, the better job possibilities and the higher level of services in urban settlements. However, it is often recognized that depopulation is related to natural factors such as elevation, slope or lithology. It is also observed that protected areas are frequently established in depopulated mountain regions. Their primary aim is the conservation of nature, but they may help tourism development as well. Tourism, in turn, may slow down or even reverse the process of depopulation. In this study, we investigate the impact of topographic and lithologic factors, namely of karst settings, on mountain demographic processes and the relationship of protected areas and tourism through the example of the northern part of Zlatibor District(Western Serbia). The study area is characterized by mountains and hills at elevations from 200 to 1600 m a.s.l. Our aim is to find GIS-based statistical relationships between topographic, lithologic factors and demographic characteristics. In this area, mountain depopulation started after WWII, and weproved that this process was strongly controlled by topographic factors. The higher and more dissected the area, the more significant is the decrease of the population and the more advanced is the ageing. As a result, population density contrasts are much more pronounced now than 70 years ago. After WWII, depopulation and ageing became gradually more serious on karstic terrains than on non-karst. However, by using compound topographic and lithologic types, we proved that it is not the effect of karst, but the effect of topography. The flow of population from hills and mountains to valleys and basins are closely related to the restructuring of the economic sectors. At present, for the study area, the development of tourism is unequivocally naturebased and connected to protected ar

关键词： Depopulation Ageing National park Tara Mountain Tourism Rural Population density

Kinetic-compartmental modelling of potassium-containing cellulose feedstock gasification

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Frontiers of Chemical Science and Engineering 2018年第4期12卷 708-717页

作者： Attila Egedy Livia Gyurik tamas Varga Jun Zou Norbert Miskolczi Haiping Yang Institute of Chemical and Process Engineering University of PannoniaVeszprem 8200Hungary State Key Laboratory of Coal Combustion Huazhong University of Science and TechnolgyWuhan 430074China

Biomass is of growing interest as a secondary energy source and can be converted to fuels with higher energy density especially by pyrolysis or gasification. Understanding the mechanism and the kinetics of biomass pyrolysis (thermal decomposition) and gasification (conversion of organic material to gases) could be the key to the design of industrial devices capable of processing vast amounts of biomass feedstock. In our work real product components obtained in pyrolysis were took into consideration as well as char and oil as lumped components, and the kinetic constants for a biomass model compound (cellulose) pyrolysis and gasification were identified based on a proposed simplified reaction mechanism within a compartment model structure. A laboratory scale reactor was used for the physical experiments containing consecutive fast pyrolysis and gasification stages using alkali metal (K) containing feedstock, which has a significant effect on the cellulose pyrolysis and gasification. The detailed model was implemented in MATLAB/Simulink environment, and the unknown kinetic parameters were identified based on experimental data. The model was validated based on measurement data, and a good agreement was found. Based on the validated first principle model the optimal parameters were determined as 0.15 mL/min steam flow rate, and 4% K content.

关键词： biomass pyrolysis kinetic parameter identification compartment modelling optimisation Compartmental models PYROLYTIC GASIFICATION Cellulose gasification pyrolysis Kinetic parameters measurement data energy density Biomass

Overview and comparison of guidelines for management of pancreatic cystic neoplasms

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World Journal of Gastroenterology 2019年第31期25卷 4405-4413页

作者： Aws Hasan Kavel Visrodia James J Farrell tamas A Gonda Division of Digestive and Liver Diseases Department of MedicineColumbia UniversityNew YorkNY 10032United States Division of Digestive Diseases Department of MedicineYale UniversityNew HavenCT 06520United States

Pancreatic cysts are identified at an increasing *** mucinous cystic neoplasms represent a pre-malignant condition,the majority of these lesions do not progress to *** the last 10 years several societies have established guidelines for the diagnosis,initial evaluation and surveillance of these *** we provide an overview of five commonly used guidelines:2015 American Gastroenterological Association,2017 International Association of Pancreatology,American College of Gastroenterology 2018,European Study Group and American College of *** describe the similarities and differences between the methods used to formulate these guidelines,the population they target and their approaches towards initial evaluation and surveillance of cystic lesions.

关键词： Pancreatic cyst surveillance Cyst malignancy Guidelines

An effective Building Neighborhood Green Index model for measuring urban green space

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International Journal of Digital Earth 2016年第4期9卷 387-409页

作者： Yuqin Liu Qingyan Meng Jiahui Zhang Linlin Zhang tamas Jancso Rumiana Vatseva Institute of remote sensing and Digital Earth Chinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina Alba Regia Technical Faculty Obuda UniversitySzekesfehervarHungary Department of Geography National Institute of GeophysicsGeodesy and GeographyBulgarian Academy of SciencesSofiaBulgaria

Urban green space forms an integral part of urban *** urban green space is of substantial importance for urban planning and *** the drawbacks of previous urban green space index models,which established either through a grid method or green distribution,and the difficulty of the validation process of earlier urban green space index models,this study exploits the advantages of multisource high-resolution remote sensing data to establish a Building Neighborhood Green Index(BNGI)*** model which analyzes the spatial configuration of built-up areas and the vegetation is based on the building-oriented method and considers four parameters–Green Index(GI),proximity to green,building sparsity,and building *** BNGI with GI in different types of characteristic building regions,it was found that BNGI evaluates urban green space more *** was also found that high-rise low-sparsity area has a lower mean value of BNGI(0.56)as compared with that of low-rise low-sparsity neighborhood(0.62),whereas mean GI(0.24)is equal for both *** characteristics of urban building and green types into consideration,BNGI model can be effectively used in many fields such as land suitability analysis and urban planning.

关键词： urban green space BNGI Green Index building-oriented method neighborhood

A Nearly Analytical Discrete Method for Wave-Field Simulations in 2D Porous Media

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Communications in Computational Physics 2006年第3期1卷 528-547页

作者： Dinghui Yang Jiming Peng Ming Lu tamas Terlaky Department of Mathematical Sciences Tsinghua UniversityBeijing 100084P.R.China Department of Computing and Software McMaster UniversityHamiltonCanada

The nearly analytic discrete method(NADM)is a perturbation method originally proposed by Yang et al.(2003)[26]for acoustic and elastic waves in elastic *** method is based on a truncated Taylor series expansion and interpolation approximations and it can suppress effectively numerical dispersions caused by the discretizating the wave equations when too-coarse grids are *** the present work,we apply the NADM to simulating acoustic and elastic wave propagations in 2D porous *** method enables wave propagation to be simulated in 2D porous isotropic and anisotropic *** experiments show that the error of the NADM for the porous case is less than those of the conventional finite-difference method(FDM)and the so-called Lax-Wendroff correction(LWC)*** three-component seismic wave fields in the 2D porous isotropic medium are simulated and compared with those obtained by using the LWC method and exact *** characteristics of wave propagating in porous anisotropic media,computed by the NADM,are also reported in this *** numerical results illustrate that the NADM provides a useful tool for large-scale porous problems and it can suppress effectively numerical dispersions.

关键词： Porous media nearly-analytic discretization three-component seismic wavefield anisotropy numerical dispersion

Effect of melatonin on the severity of L-arginine-induced experimental acute pancreatitis in rats

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World Journal of Gastroenterology 2006年第2期12卷 251-258页

作者： Annamaria Szabolcs Russel J Reiter tamas Letoha Peter Hegyi Gabor Papai Ilona Varga Katalin Jarmay Jozsef Kaszaki Reka Sari Zoltan Rakonczay Jr Janos Lonovics tamas Takacs st Department of Medicine University of SzegedHungary Department of Cellular and Structural Biology University of TexasHealth Science CentreSan AntonioTexasUnited States Institute of Chemistry University of SzegedHungary Biological Research Centre Hungarian Academy of SciencesSzegedHungary Biological Isotope Laboratory University of SzegedHungary Institute of Experimental Surgery University of SzegedHungary

AIM： To determine the effect of melatonin pre- and post-treatment on the severity of L-arginine （L-Arg） -induced experimental pancreatitis in rats. METHODS： Male Wistar rats （25） were divided into five groups. Those in group A received two injections of 3.2 g/kg body weight L-Arg i.p. at an interval of 1 h. In group MA, the rats were treated with 50 mg/kg body weight melatonin i.p. 30 min prior to L-Arg administration. In group AM, the rats received the same dose of melatonin 1 h after L-Arg was given. In group M, a single dose of melatonin was administered as described previously. In group C the control animals received physiological saline injections i.p. All rats were exsanguinated 24 h after the second L-Arg injection. RESULTS： L-Arg administration caused severe necrotizing pancreatitis confirmed by the significant elevations in the serum amylase level, the pancreatic weight/body weight ratio （pw/bw）, the pancreatic IL-6 content and the myeloperoxidase activity, relative to the control values. Elevation of the serum amylase level was significantly reduced in rats given melatonin following L-Arg compared to rats injected with L-Arg only. The activities of the pancreatic antioxidant enzymes （Cu/Zn-superoxide dismutase （CulZn-SOD） and catalase （CAT）） were significantly increased 24 h after pancreatitis induction. Melatonin given in advance of L-Arg significantly reduced the pancreatic CAT activity relative to that in the rats treated with L-Arg alone. In the liver, L-Arg significantly increased the lipid peroxidation level, and the glutathione peroxidase and Cu/Zn-SOD activities, whereas the Mn-SOD activity was reduced as compared to the control rats. Melatonin pre-treatment prevented these changes. CONCLUSION： Melatonin is an antioxidant that is able to counteract some of the L-Arg-induced changes during acute pancreatitis, and may therefore be helpful in the supportive therapy of patients with acute necrotizing pancreatitis.

关键词： Acute pancreatitis Melatonin Scavengers

Inland-coastal demographic transformations in a karst area:a case study of the surroundings of Krka National Park(Croatia)

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Journal of Mountain Science 2022年第2期19卷 305-321页

作者： TELBISZ tamas RADELJAK KAUFMANN Petra BOCIC Neve Department of Physical Geography Eotvos Lorand UniversityPazmany Peter setany 1/CBudapest 1117Hungary Department of Geography Faculty of ScienceUniversity of ZagrebMarulicev trg 19/IIZagreb 10000Croatia

According to geographic possibilism,environment does not determine socio-economic ***,the environment sets certain constraints and limitations for *** do natural settings influence population dynamics?In this study,we examine this question using the example of?ibenik-Knin County,which includes Krka National Park(NP)with a GIS-based statistical *** following parameters represent natural factors:elevation,slope,distance from water,and proportion of karst *** addition,distance from Krka NP was also added as an independent seminatural factor(despite the fact that it is a social construction).The dependent social parameters are population density for selected historical dates,population change,year of maximum population,natural increase,migration,and age *** analysis units are the 199 settlements found in the county,and the 20 local administrative units(LAU2).The study period can be divided into five phases:from the first census in 1857 to 1921,there was a slow increase in most settlements;then a relatively constant phase up to 1961(some settlements began shrinking in this period);a slow decrease until 1991;arapid decrease during the next decade;and relative stabilisation to present *** processes were also accompanied by significant inner and outer *** for the relationships between natural and demographic factors,we found that although the coastal-inland area dichotomy is dominant in the study area,elevation has the highest correlation with most population ***,distance from water is also significantly correlated with population change and migration in certain *** the inland areas,there are statistically significant differences between the demographic processes of fully-karstic and partially-karstic areas,while in the coastal zone,the karst effect is overshadowed by other social *** impact of Krka NP on the demographic characteristics of the surrounding settlements was statisti

关键词： Geographic possibilism Karst National park Population density Migration

Growth control of peptide-nanotube spherulitic films： Experiments and simulations

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Nano Research 2015年第11期8卷 3630-3638页

作者： Netta Hendler Elad Mentovich Balint Korbuly tamas Pusztai Laszlo Granasy Shachar Richter Department of Materials Science and Engineering Faculty of Engineering Tel Aviv University Ramat Aviv Tel Aviv 69978 Israel Center for Nanoscience and Nanotechnology Tel Aviv University Ramat Aviv Tel Aviv 69978 Israel Wigner Research Centre for Physics P.O. Box 49 H- 1525 Budapest Hungary Brunel Centre forAdvanced Solidification Technology Brunel University Uxbridge Middlesex UB8 3PH UK

Multi-hierarchical self-assembly （MHSA） is a key process responsible for the spontaneous formation of many complex structures. However, because of the complexity of the process, the underlying mechanism remains largely unclear. Thus, a deeper understanding of MHSA is required, especially for the preparation of MHSA systems via bottom-up methodologies. We show here, experimentally and theoretically, that the complex-formation MHSA of peptide nanotube films can be controlled solely by manipulating the experimental parameter of humidity. Furthermore, we identify growth-front nucleation （GFN; the formation of new grains at the perimeter） as the physical background for the observed morphological transitions by correlating experimental observations with phase-field modeling of the morphological evolution. Our findings indicate a simple way to control multi-hierarchical morphologies, crucial for the employment of bottom-up techniques in constructing complex structures for practical applications.

关键词： multi-hierarchical self-assembly growth-front nucleation peptide nanotubes spherulite crystallization experiment vs. phase-field modeling