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Oncology Research 2024年第8期32卷 1323-1334页

作者： RUIFANG li XINRONG NAN MING li OMAR RAHHAL School of Stomatology Shanxi Medical UniversityTaiyuan030001China Department of Stomatology The First Hospital of Shanxi Medical UniversityTaiyuan030001China Department of Oral and Maxillofacial Surgery Xiangya Stomatology HospitalCentral South UniversityChangsha410005China

Background:Fibroblast activation protein(FAP),a cell surface serine protease,plays roles in tumor invasion and immune ***,there is currently no pan-cancer analysis of ***:We aimed to assess the pan-cancer expression proﬁle of FAP,its molecular function,and its potential role in head and neck squamous cell carcinoma(HNSC).Methods:We analyzed gene expression,survival status,immune inﬁltration,and molecular functional pathways of FAP in The Cancer Genome Atlas(TCGA)and Genotype Tissue Expression(GTEx)***,to elucidate the role of FAP in HNSC,we performed proliferation,migration,and invasion assays post-FAP overexpression or ***:FAP expression was elevated in nine tumor types and was associated with poor survival in eight of *** the context of immune inﬁltration,FAP expression negatively correlated with CD8+T-cell inﬁltration inﬁve tumor types and positively with regulatory T-cell inﬁltration in four tumor *** enrichment analysis highlighted FAP’s involvement in the PI3K-Akt signaling *** HNSC cells,FAP overexpression activated the PI3K-Akt pathway,promoting tumor proliferation,migration,and ***,FAP knockdown showed inhibitory ***:Our study unveils the association of FAP with poor tumor prognosis across multiple cancers and highlights its potential as a therapeutic target in HNSC.

关键词： FAP Head and neck squamous cell carcinoma Cancer Prognosis Tumor microenvironment Molecular function

Contrasting strategies of optimizing carrier concentration in bulk InSe for enhanced thermoelectric performance

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Rare Metals 2024年第9期43卷 4425-4432页

作者： Hao-Nan Shi Shu-lin Bai Yu-Ping Wang li-Zhong Su Qian Cao Cheng Chang li-Dong Zhao School of Materials Science and Engineering Beihang UniversityBeijing 100191China School of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024China Huabei Cooling Device Co.Ltd. Hebei 065400China

Indium selenide(InSe),as a wide-bandgap semiconductor,has received extensive attention in the flexible electronics field in recent years due to its exceptional plasticity and promising thermoelectric ***,the low carrier concentration severely limits its thermoelectric performance *** this work,we conducted contrasting strategies that can be employed to increase the carrier concentration of InSe,including bandgap narrowing and heterovalent ***,the carrier concentration initially increases as a result of the reduced bandgap upon Te alloying and then slightly decreases due to the weak electronegativity of *** Br doping realizes high carrier concentration by pushing the Fermi level into the conduction bands and activating the multiple *** the other hand,both Te and Br obviously suppress the thermal conductivity due to the point defect *** contrast,Br doping realizes a higher thermoelectric performance with a maximum ZT of~0.13 at 773 K benefiting from the better optimization of carrier *** work elucidates the strategies for enhancing carrier concentration at anion sites and demonstrates the high efficiency of halogen doping in ***,the carrier concentration of InSe is promising to be further optimized,and future work should focus on employing approaches such as cation doping or secondphase compositing.

关键词： Thermoelectric InSe Carrier concentration Bandgap Heterovalent doping

Methyl functionalization of trimesic acid in copper-based metal-organic framework for ammonia colorimetric sensing at high relative humidity

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Chinese Chemical Letters 2024年第6期35卷 211-215页

作者： Yuxin Wang Zhengxuan Song Yutao liu Yang Chen Jinping li libo li Jia Yao College of Chemical Engineering and Technology Shanxi Key Laboratory of Gas Energy Efficient and Clean UtilizationTaiyuan University of TechnologyTaiyuan 030024China Department of Gastroenterology Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuan 030024China

Exhaled ammonia(NH_(3))can be used as a crucial biomarker of kidney and liver ***,the high humidity in the detection conditions remains a challenge for accurate detection by gas ***,a copper-based metal-organic framework(CH_(3)-Cu-BTC)with methyl(CH_(3)^(-))functionalization of trimesic acid was synthesized for NH_(3) colorimetric *** CH_(3)-Cu-BTC exhibited a strong response for 5 ppm NH_(3) with high selectivity under high relative humidity(75%RH).Density functional theory(DFT)simulations indicated that the NH_(3) molecules interacted more strongly with CH_(3)-Cu-BTC than H_(2)O molecules did,and the corresponding color switching was attributed to the lone-pair electron in NH_(3) changing the coordination environment of Cu^(2+)ions,leading to an obviously visible color switching response from ruby green to *** on the tailor-made pore chemistry,the precise detection of trace amounts of NH_(3) in exhaled air was realized through functionalized MOF *** strategy used in this study not only offers a new pathway for the rapid detection of low concentration NH_(3) under humid conditions,but also shows a method for early respiration diagnosis of kidney and liver diseases.

关键词： Metal-organic framework Ammonia sensing Naked-eye color switching High humidity Respiration diagnosis

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关于灌木生物量建模方法的改进

生态学杂志 1993年第6期12卷 67-69页

作者：张峰上官铁梁李素珍山西大学生物系太原治金工业学校

关于灌木生物量建模方法的改进张峰，上官铁梁李素珍（山西大学生物系，太原０３０００６）（太原治金工业学校，０３０００２）ＩｍｐｒｏｖｅｍｅｎｔｏｎｔｈｅＭｏｄｅｌｌｉｎｇＭｅｔｈｏｄｏｆＢｉｏｌｍａｓｓｏｆＢｒｕｓｈ￥... 详细信息

关于灌木生物量建模方法的改进张峰，上官铁梁李素珍（山西大学生物系，太原０３０００６）（太原治金工业学校，０３０００２）ＩｍｐｒｏｖｅｍｅｎｔｏｎｔｈｅＭｏｄｅｌｌｉｎｇＭｅｔｈｏｄｏｆＢｉｏｌｍａｓｓｏｆＢｒｕｓｈ￥ＺｈａｎｇＦｅｎｇ；ＳｈａｎｇｇｕａｎＴｉｅｌｉａｎｇ（Ｄｅｐａｒｔ－ｍｅｎｔｏｆＢｉｏｌｏｇｙ，ＳｈａｎｘｉＵｎｉｖｅｒｓｉｔｙ，Ｔａｉｙｕａｎ０３０００６），ＬｉＳｕｚｈｅｎ（ＴａｉｙｉｉａｎＭｅｔａｌｌｉｔｒｇｉｃａｌＳｃｈｏｏｌ，Ｔａｉｙｕａｎ０３０００２）．ＣｈｉｎｅｓｅＪｏｕｒｎａｌｏｆＶＥｃｏｌｏｇｙ，１９９３，１２（６）：６７－６９．ＤｕｒｉｎｇｍａｋｉｎｇｒｅｓｅａｒｃｈｏｎｔｈｅｂｉｏｍａｓｓｏｆＥｌａｅａｇｎｕｓｍｏｌｌｉｓ，ｔｈｅｒｅｇｒｅｓｓｉｏｎｍｏｄｅｌｏｆｔｈｅｂｉｏｍａｓｓｉｓｂｕｉｌｔｂｙｒｅｐｌａｃｉｎｇＤ￣２ＨｗｉｔｈＣＨ，Ｔｈｅｒｅｓｕｌｔｓｈｏｗｓｔｈａｔｎｏｔｏｎｌｙｉｔｉｓｃｏｎｖｉｎｉｅｎｔｉｎｔｈｅｆｉｅｌｄｗｏｒｋ。

关键词：灌木生物量生物模型建立模型

STDNet: A Spatio-Temporal Decomposition Neural Network for Multivariate Time Series Forecasting

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Tsinghua Science and Technology 2024年第4期29卷 1232-1247页

作者： Zhuolun Jiang Zefei Ning Hao Miao li Wang College of Computer Science and Technology(College of Data Science) Taiyuan University of TechnologyJinzhong 030600China

Long-term multivariate time series forecasting is an important task in engineering applications. It helps grasp the future development trend of data in real-time, which is of great significance for a wide variety of fields. Due to the non-linear and unstable characteristics of multivariate time series, the existing methods encounter difficulties in analyzing complex high-dimensional data and capturing latent relationships between multivariates in time series, thus affecting the performance of long-term prediction. In this paper, we propose a novel time series forecasting model based on multilayer perceptron that combines spatio-temporal decomposition and doubly residual stacking, namely Spatio-Temporal Decomposition Neural Network (STDNet). We decompose the originally complex and unstable time series into two parts, temporal term and spatial term. We design temporal module based on auto-correlation mechanism to discover temporal dependencies at the sub-series level, and spatial module based on convolutional neural network and self-attention mechanism to integrate multivariate information from two dimensions, global and local, respectively. Then we integrate the results obtained from the different modules to get the final forecast. Extensive experiments on four real-world datasets show that STDNet significantly outperforms other state-of-the-art methods, which provides an effective solution for long-term time series forecasting.

关键词： time series forecasting multivariate time series spatio-temporal decomposition

The source of lithium in Lakkor Co Salt Lake on Qinghai-Tibet Plateau,China:evidence from hydrochemical characteristics and boron isotope

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Acta Geochimica 2024年第5期43卷 933-946页

作者： Zheng Yan li Bin Kai li Mao-Yong He Xue Qin Wen Jiang Di Zhou Department of Geoscience and Technology Taiyuan University of TechnologyYingzexi StreetTaiyuan 030024Shanxi ProvinceChina State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China Qinghai Provincial Key Laboratory of Geology and Environment of Salt Lakes Qinghai Institute of Salt LakesChinese Academy of SciencesXining 810008QinghaiChina School of Earth Science and Resources Chang’an UniversityXi’an 710000ShaanxiChina Qinghai Normal University Academy of Plateau Science and SustainabilityXining 810016China

The availability of lithium resources is of great significance for the development of modern technologies,as well as for civil and military *** Qinghai-Tibet Plateau is a region known for its abundance of lithium-rich salt ***,the specific origin of lithium in these lakes is still unknown,which hinders the advancement of the lithium resource business in this *** research this issue,this study involved the collection of 20 samples from Lakkor Co Salt Lake on Qinghai-Tibet Plateau,encompassing samples of surface brine,cold springs,fresh lakes,and recharge *** composition of anions and cations in these samples was ***,the analysis extensivelyutilizedthePiperthree-linediagram,Gibbs model,and ion proportion *** findings of this study indicate that as the moves from the recharge water system to salt lake,there is a transition in water type from strong carbonate to moderate carbonate and weak carbonate,as well as Na *** research based on a similar source of both lithium and boron,utilized ion correlation analysis and boron isotope study in the Lakkor Co area,and analyzed the source and transporting process of *** main origin of lithium in Lakkor Co is the dissolution of lithiumrich rocks,recharge water systems,and deep hydrothermal *** findings are highly significant in enhancing the foundational data of lithium-rich brine resources in the Qinghai-Tibet Plateau and are beneficial for assessing the future development of such deposits.

关键词： lithium Hydrochemical li-rich Salt lake Boron isotope

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非线性蛇簧联轴器振动特性研究

太原重型机械学院学报 1995年第2期16卷 157-168页

作者：殷玉枫刘中李质芳刘晓雯太原重型机械学院基础部西安交通大学山西省公路局

本文给出了非线性蛇簧联轴器的刚度曲线计算公式，分析了非线性蛇簧联轴器在系统的频率与激振频率满足一定条件而发生共振时，可以自动地中断振幅危险增长的特性，给出了幅频反应曲线和载荷系数计算公式，提出了非线性蛇簧联轴器的设计... 详细信息

本文给出了非线性蛇簧联轴器的刚度曲线计算公式，分析了非线性蛇簧联轴器在系统的频率与激振频率满足一定条件而发生共振时，可以自动地中断振幅危险增长的特性，给出了幅频反应曲线和载荷系数计算公式，提出了非线性蛇簧联轴器的设计准则，讨论了非线性蛇簧联轴器的基本本数。

关键词：非线性联轴器蛇簧联轴器振动

IQABC-Based Hybrid Deployment Algorithm for Mobile Robotic Agents Providing Network Coverage

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Tsinghua Science and Technology 2024年第2期29卷 589-604页

作者： Shuang Xu Xiaojie liu Dengao li Jumin Zhao College of Computer Science and Technology(College of Data Science) Taiyuan University of TechnologyTaiyuan 030024China Pengcheng Laboratory Shenzhen 518055China College of Information and Computer Taiyuan University of TechnologyTaiyuan 030024China

Working as aerial base stations,mobile robotic agents can be formed as a wireless robotic network to provide network services for on-ground mobile devices in a target ***,a challenging issue is how to deploy these mobile robotic agents to provide network services with good quality for more users,while considering the mobility of on-ground *** this paper,to solve this issue,we decouple the coverage problem into the vertical dimension and the horizontal dimension without any loss of optimization and introduce the network coverage model with maximum coverage ***,we propose a hybrid deployment algorithm based on the improved quick artificial bee *** algorithm is composed of a centralized deployment algorithm and a distributed *** proposed deployment algorithm deploy a given number of mobile robotic agents to provide network services for the on-ground devices that are independent and identically *** results have demonstrated that the proposed algorithm deploys agents appropriately to cover more ground area and provide better coverage uniformity.

关键词： wireless robotic networks network coverage deployment algorithm improved quick artificial bee colony

矿物质复合微量元素对乳酸菌生长及生物学特征的影响

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延边大学农学学报 2018年第2期40卷 76-81页

作者：孔洁张涵李亭玉李艳茹张敏李太元延边大学农学院吉林延吉133002

乳酸菌作为肠道益生菌群,在维持肠道内菌群平衡及消化运动功能上起到重要作用。为了研究天然矿物微量元素复合制剂对乳酸菌的生长及生物学特性的影响,选择保加利亚乳杆菌、李糖鼠乳杆菌、乳酸乳球菌和嗜酸乳杆菌的标准菌株作为试验菌种... 详细信息

乳酸菌作为肠道益生菌群,在维持肠道内菌群平衡及消化运动功能上起到重要作用。为了研究天然矿物微量元素复合制剂对乳酸菌的生长及生物学特性的影响,选择保加利亚乳杆菌、李糖鼠乳杆菌、乳酸乳球菌和嗜酸乳杆菌的标准菌株作为试验菌种,对乳酸菌的增殖、酸碱耐受性、温度耐受性、细菌生长曲线及其代谢产物的抑菌效果等进行试验。结果表明:矿物粉对保加利亚乳杆菌、李糖鼠乳杆菌、乳酸乳球菌和嗜酸乳杆菌均起到增菌作用,其最适作用浓度分别为0.1、0.25、0.25和0.5g/mL,矿物质微量元素对乳酸菌的酸碱耐受性、温度耐受性及细菌抑菌作用等具有一定的提高效果。

关键词：矿物质复合元素乳酸菌细菌增殖生物学特征

The Response of Carbonate System to Watershed Urbanization Process in a Semi-Arid River

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Journal of Ocean University of China 2024年第4期23卷 991-1002页

作者： li Yunxiao DANG Jiajia HUANG Xiao YANG Hong WANG Xiao li lina BAI Jie CHEN Xi Department of Environmental Science College of Resource and EnvironmentShanxi Agricultural UniversityTaigu 030801China Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control Collaborative Innovation Center of Atmospheric Environment and Equipment TechnologySchool of Environmental Science and EngineeringNanjing University of Information Science and TechnologyNanjing 210044China Department of Geography and Environmental Science University of ReadingWhiteknightsReading RG66ABUK Marine Agriculture Research Center Tobacco Research InstituteChinese Academy of Agricultural SciencesQingdao 266101China 5 Key Laboratory of Marine Environmental Science and Ecology Ministry of EducationCollege of Environmental Science and EngineeringOcean University of ChinaQingdao 266100China

Different from rivers in humid areas,the variability of riverine CO_(2) system in arid areas is heavily impacted by anthropogenic disturbance with the increasing urbanization and water *** this study,the water chemistry and the controls of carbonate system in an urbanized river(the Fenhe River)on the semi-arid Loess Plateau were *** water chemistry of the river water showed that the high dissolved inorganic carbon(DIC)concentration(about 37 mg L^(-1))in the upstream with a karst land type was mainly sourced from carbonate weathering involved by H_(2)CO_(3) and H_(2)SO_(4),resulting in an oversaturated partial pressure of CO_(2)(pCO_(2))(about 800μatm).In comparison,damming resulted in the widespread appearance of non-free flowing river segments,and aquatic photosynthesis dominated the DIC and pCO_(2) spatiality demonstrated by the enriched stable isotope of DIC(δ^(13)CDIC).Especially in the mid-downstream flowing through major cities in warm and low-runoff August,some river segments even acted as an atmospheric CO_(2) *** noteworthy is wastewater input leading to a sudden increase in DIC(>55 mg L^(-1))and pCO_(2)(>4500μatm)in the downstream of taiyuan City,and in cold November the increased DIC even extended to the outlet of the *** results highlight the effects of aquatic production induced by damming and urban sewage input on riverine CO_(2) system in semi-arid areas,and reducing sewage discharge may mitigate CO_(2) emission from the rivers.

关键词： dissolved inorganic carbon stable carbon isotope carbonate weathering aquatic photosynthesis sewage input the Fenhe River