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Three cases of retroperitoneal schwannoma diagnosed by EUS-FNA

World Journal of Gastroenterology 2011年第29期17卷 3459-3464页

作者： taiki kudo Hiroshi Kawakami Masaki Kuwatani Nobuyuki Ehira Hiroaki Yamato Kazunori Eto Kanako Kubota Masahiro Asaka Department of Gastroenterology Hokkaido University Graduate School of MedicineKita 15Nishi 7Kita-kuSapporo060-8638Japan Department of Surgical pathology Hokkaido University HospitalKita 14Nishi 5Kita-kuSapporo060-8638Japan

Schwannomas are peripheral nerve tumors that are typically solitary and *** diagnosis is largely based on surgically resected ***,a number of case reports have indicated that retroperitoneal schwannomas could be diagnosed with endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA).We report the diagnosis of three cases of schwannoma using *** were two males and one female,ages 22,40,and 46 years,respectively,all of whom were *** findings showed well-circumscribed round ***,as the tumors could not be diagnosed using these findings alone,EUS-FNA was ***-eosin staining of the resulting tissue fragments revealed bland spindle cells with nuclear *** was no disparity in nuclear *** revealed S-100 protein positivity and all cases were diagnosed as ***-67 indexes were 3%-15%,2%-3%,and 3%,*** case showed any signs of *** most schwannomas are benign tumors and seldom become malignant,we observed these patients without *** tumors demonstrated no enlargement and no change in *** are almost always benign and can be observed following diagnosis by EUS-FNA.

关键词：周围神经诊断腹膜良性肿瘤病例报告免疫染色手术切除外切圆

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Influence of the safety and diagnostic accuracy of preoperative endoscopic ultrasound-guided fine-needle aspiration for resectable pancreatic cancer on clinical performance

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World Journal of Gastroenterology 2014年第13期20卷 3620-3627页

作者： taiki kudo Hiroshi Kawakami Masaki Kuwatani Kazunori Eto Shuhei Kawahata Yoko Abe Manabu Onodera Nobuyuki Ehira Hiroaki Yamato Shin Haba Kazumichi Kawakubo Naoya Sakamoto Department of Gastroenterology and Hepatology Hokkaido University Graduate School of MedicineSapporo 060-8638Japan

AIM:To evaluate the safety and diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA)in a cohort of pancreatic cancer ***:Of 213 patients with pancreatic cancer evaluated between April 2007 and August 2011,82were thought to have resectable pancreatic cancer on the basis of cross-sectional imaging *** these,54 underwent EUS-FNA before surgery(FNA+group)and 28 underwent surgery without preoperative EUSFNA(FNA-group).RESULTS:All 54 lesions were visible on EUS,and all54 attempts at FNA were technically *** diagnostic accuracy according to cytology and histology findings was 98.1%(53/54)and 77.8%(42/54),respectively,and the total accuracy was 98.1%(53/54).One patient developed mild pancreatitis after EUS-FNA but was successfully treated by conservative *** severe complications occurred after *** the FNA+and FNA-groups,the median relapse-free survival(RFS)was 742 and 265 d,respectively(P=0.0099),and the median overall survival(OS)was1042 and 557 d,respectively(P=0.0071).RFS and OS were therefore not inferior in the FNA+*** data indicate that the use of EUS-FNA did not influence RFS or OS,nor did it increase the risk of peritoneal ***:In patients with resectable pancreatic cancer,preoperative EUS-FNA is a safe and accurate diagnostic method.

关键词： Pancreatic cancer Diagnosis Biopsy Endo-scopic ult

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Retrospective cohort study Lower incidence of complications in endoscopic nasobiliary drainage for hilar cholangiocarcinoma

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World Journal of Gastrointestinal Endoscopy 2016年第9期8卷 385-390页

作者： Kazumichi Kawakubo Hiroshi Kawakami Masaki Kuwatani Shin Haba taiki kudo Yoko A Taya Shuhei Kawahata Yoshimasa Kubota Kimitoshi Kubo Kazunori Eto Nobuyuki Ehira Hiroaki Yamato Manabu Onodera Naoya Sakamoto Department of Gastroenterology and Hepatology Hokkaido University Graduate School of Medicine Sapporo 0608638Japan

AIM:To identify the most effective endoscopic biliary drainage technique for patients with hilar ***:In total,118 patients with hilar cholangiocarcinoma underwent endoscopic management[endoscopic nasobiliary drainage(ENBD)or endoscopic biliary stenting]as a temporary drainage in our institution between 2009 and *** retrospectively evaluated all complications from initial endoscopic drainage to surgery or palliative *** risk factors for biliary reintervention,post-endoscopic retrograde cholangiopancreatography(post-ERCP)pancreatitis,and percutaneous transhepatic biliary drainage(PTBD)were also analyzed using patient-and procedure-related *** risk factors for bilateral drainage were examined in a subgroup analysis of patients who underwent initial unilateral ***:In total,137 complications were observed in92(78%)*** reintervention was required in 83(70%)*** was significantly associated with a low risk of biliary reintervention[odds ratio(OR)=0.26,95%CI:0.08-0.76,P=0.012].Post-ERCP pancreatitis was observed in 19(16%)*** absence of endoscopic sphincterotomy was significantly associated with post-ERCP pancreatitis(OR=3.46,95%CI:1.19-10.87,P=0.023).PTBD was required in 16(14%)patients,and Bismuth type III or IV cholangiocarcinoma was a significant risk factor(OR=7.88,95%CI:1.33-155.0,P=0.010).Of 102 patients with initial unilateral drainage,49(48%)required bilateral *** sphincterotomy(OR=3.24,95%CI:1.27-8.78,P=0.004)and Bismuth II,III,or IV cholangiocarcinoma(OR=34.69,95%CI:4.88-736.7,P<0.001)were significant risk factors for bilateral ***:The endoscopic management of hilar cholangiocarcinoma is *** should be selected as a temporary drainage method because of its low risk of complications.

关键词： Hilar cholangiocarcinoma Endoscopic nasobiliary drainage Endoscopic biliary stenting Endoscopic sphincterotomy Complications

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