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ROS-induced metabolic reprogramming to one-carbon metabolism and S-adenosylmethionine-mediated epigenetic modification in IL-10-producing B cells for the resolution of pneumonia

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Cellular & Molecular Immunology 2024年第2期21卷 203-204页

作者： Sujin Lee tae Jin kim Department of Immunology Sungkyunkwan University School of MedicineSuwon16419Republic of Korea

B cells have an essential immunoregulatory function,which is mediated by the secretion of IL-10 and TGFβand interaction with activated CD4^(+)T *** antibody-independent function of B cells contributes to ameliorating autoimmune diseases or infection-induced tissue *** this Cellular and Molecular Immunology issue,Fu et *** that regulatory B(Breg)cells play a critical role in resolving Pseudomonas aeruginosa-induced pneumonia[1].

关键词： metabolism pneumonia Immunology

Fabrication and Characterization of Electrodeposited Ni-SiC-h/BN Composite Coatings

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Journal of Materials Science & Technology 2014年第8期30卷 796-802页

作者： Gobinda Gyawali Hyung-Suk kim Khagendra Tripathi tae-Ho kim Soo Wohn Lee Research Center for Eco-Multifunctional Nano Materials Sun Moon UniversityAsanRepublic of Korea Department of Environmental Engineering Sun Moon UniversityChungnam 336-708Republic of Korea

Ni—SiC—h/BN composite materials were prepared by electrodeposition technique with the dispersion of SiC（10 g/L） and h/BN nanosheets（10 g/L） in a nickel sulfamate electrolytic *** ratio of sodium dodecyl sulfate（SDS） and cetyltrymethyl ammonium bromide（CTAB） surfactants were used to evaluate the effect of surfactants on the properties of the electrodeposited composite *** coating samples were characterized by scanning electron microscopy,X-ray diffraction,Vickers microhardness test,scratch and tribology *** results revealed that the co-deposition of nanoparticles was significantly influenced by surfactants during electrodeposition *** or polyhedral nickel crystallites were observed at higher ratio of SDS/CTAB while smaller oval grains with refined surface morphologies were obtained at lower ratio of SDS/CTAB *** addition,wt%of particles co-deposition was increased,and Vickers microhardness,wear and coefficient of friction of the electrodeposited composite coatings were improved at increased CTAB and decreased SDS contents in the electrolyte during electrodeposition process.

关键词： Ni-SiC-h/BN Composite coating Surfactant Microstructure Scratch Wear

Effect of Nozzle Geometry on the Flow Characteristics of Spiral Flow Generated through an Annular Slit

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Journal of Thermal Science 2007年第2期16卷 149-154页

作者： Shigeru MATSUO tae-Hun kim Toshiaki SETOGUCHI Heuy Dong kim Yeon-Won LEE Department of Mechanical Engineering Saga University1Honjo-machiSaga-shiSaga 840-8502Japan Graduate school of Science and Technology Saga University1Honjo-machiSaga shiSaga 840-8502Japan School of Mechanical Engineering Andong National University388Songchun-dongAndong 760749Korea School of Mechanical Engineering College of EngineeringPukyong National UniversitySan 100Young-Dang DongBusanKorea

In comparison with previous researches of swirling flow, spiral flow generated in the spiral nozzle has some different flow characteristics. It does not need a forced tangential momentum to generate its velocity and has some different merits from the swirling flow such as long potential core and low tangential velocity. In this study, the effect of nozzle geometry on the flow characteristics in spiral nozzle was investigated by experiment and computation. As a result, the flow characteristics obtained by experiment has a satisfactory agreement with computational results, quantitatively and qualitatively.

关键词： nozzle flow characteristics momentum numerical simulation

Glutamic acid supplementation recovers the reduced performance of weanling pigs fed reduced crude protein diets

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Animal Nutrition 2022年第1期8卷 249-255页

作者： Santi D.Upadhaya Sang Seon Lee Young hwa kim Zhenlong Wu In Ho kim Department of Animal Resource and Science Dankook UniversityNo.29 AnseodongCheonanChoongnam 31116South Korea National Institute of Animal Science 114 Sinbangro-1 GilSeongjwan-eupSeobuk-guCheonan-si31000South Korea State Key Laboratory of Animal Nutrition Department of Animal Nutrition and Feed ScienceChina Agricultural UniversityBeijing 100193China

This study was conducted to evaluate the supplementation of glutamic acid(Glu)to reduced protein diets on the performance of weanling *** hundred and eighty crossbred weanling pigs([YorkshireLandrace]Duroc,21 d old)having similar body weight(BW)of 6.45 kg were randomly allotted to 1 of 6 dietary treatments(5 pigs per pen[2 barrows and 3 gilts];6 pens per treatment)based on BW and sex during a 6-week *** treatments consisted of positive control(PC)diet formulated to have 226.9,205.6,and 188.8 g crude protein(CP)during phases 1,2,and 3,respectively,and negative control(NC)diets with 20 g CP reduction from PC diets and addition of Glu with increasing levels,resulting in the calculated Lys-to-Glu ratios of 1:2.25,1:2.30.1:2.35,1:2.40,and 1:2.45,designated as NC,NC1,NC2,NC3,and NC4,*** BW of pigs receiving PC diet was higher(P<0.05)than those receiving NC diet at d 7,21 and 42.A higher(P<0.05)average daily gain(ADG)from d 1 to 7,8 to 21,22 to 42 and during the overall experiment period was observed in pigs fed PC than NC *** fed NC diets including the graded level of Glu linearly increased(P<0.05)BW at d 42,ADG and gain-to-feed ratio(G:F)during the overall experimental *** addition,trends in linear increase in BW(P=0.056)at d 7 and ADG from d 1 to 7 and d 22 to 42(linear effect,P=0.081,P=0.058 respectively)were observed.A tendency in the linear increment of NH3(P=0.082)at d 21 and linear reduction in methyl mercaptans(P=0.054)emission at d 42 was observed in pigs fed NC diets supplemented with graded level of *** conclusion,supplementing the reduced protein diet with Glu enhanced the growth performance in weanling pigs suggesting that supplementation of Glu can compensate the reduction of 2%CP in the basal diets.

关键词： Glu Growth performance Reduced protein diet Weanling pig

Spectrum of mucin-producing neoplastic conditions of the abdomen and pelvis:Cross-sectional imaging evaluation

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World Journal of Gastroenterology 2011年第43期17卷 4757-4771页

作者： Nam Kyung Lee Suk kim Hyun Sung kim tae Yong Jeon Gwang Ha kim Dong Uk kim Do Youn Park tae Un kim Dae hwan Kang Department of Radiology Pusan National University Hospital Medical Research Institute Pusan National University School of Medicine Pusan National University Department of Surgery Pusan National University Hospital Department of Internal Medicine Pusan National University Hospital Department of Pathology Pusan National University Hospital Department of Radiology Yangsan Pusan National University Hospital Medical Research Institute Pusan National University School of Medicine Department of Internal Medicine Yangsan Pusan National University Hospital

Various mucin-producing neoplasms originate in different abdominal and pelvic *** neoplasms differ from non-mucinous neoplasms because of the differences in clinical outcome and imaging *** carcinoma,in which at least 50%of the tumor is composed of large pools of extracellular mucin and columns of malignant cells,is associated with a worse *** ring cell carcinoma is characterized by large intracytoplasmic mucin vacuoles that expand in the malignant cells with the nucleus displaced to the *** prognosis is also generally *** contrast,intraductal papillary mucinous neoplasm of the bile duct and pancreas,which is characterized by proliferation of ductal epithelium and variable mucin production,has a better prognosis than other malignancies in the pancreaticobiliary *** modalities play a critical role in differentiating mucinous from non-mucinous *** to high water content,mucin has a similar appearance to water on ultrasound(US) ,computed tomography(CT) ,and magnetic resonance imaging,except when thick and proteinaceous,and then it tends to be hypoechoic with fine internal echoes or have complex echogenicity on US,hyperdense on CT,and hyperintense on T1and hypointense on T2-weighted images,compared to ***,knowledge of characteristic mucin imaging features is helpful to diagnose various mucinproducing neoplastic conditions and to facilitate appropriate treatment.

关键词： Mucin Neoplasm Ultrasound Computed tomography Magnetic resonance Abdomen and pelvis

Colorectal stenting:An advanced approach to malignant colorectal obstruction

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World Journal of Gastroenterology 2014年第43期20卷 16020-16028页

作者： Sung Pil Hong tae Il kim Division of Gastroenterology Department of Internal MedicineYonsei University College of MedicineSeoul 120-752South Korea

Some colorectal cancer(CRC)patients present symptoms of bowel obstruction,which is considered a surgical *** of poor medical condition and high incidence of post-surgical complications,there has been increasing use of self-expanding metal stents(SEMS)for the purpose of palliation or as a bridge to surgery with some benefits,including shorter hospital stays,lower rates of adverse events,and one-stage ***,with increasing survival of CRC patients,there have been controversial data on clinical outcomes and complications,compared between SEMS use and surgery for treatment of malignant bowel *** review recent clinical data on clinical outcomes of SEMS use compared to surgery,including complications.

关键词： Colon Cancer Obstruction Stent Palliation

A conformal titanyl phosphate amorphous overlayer for enhancing photoelectrochemical hydrogen peroxide production

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Journal of Energy Chemistry 2023年第11期86卷 399-408,I0009页

作者： Jaekyum kim Young Eun kim Minyeong Je Won tae Hong Chang-Lyoul Lee tae-Hoon kim Sung Min Cho Chang Hyuck Choi Heechae Choi Woo-Seok Choe Jung Kyu kim School of Chemical Engineering Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea SKKU Advanced Institute of Nano Technology(SAINT) Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea Theoretical Materials&Chemistry Group Institute of Inorganic ChemistryUniversity of CologneGreinstr.650939CologneGermany Advanced Photonics Research Institute(APRI) Gwangju Institute of Science and Technology(GIST)Gwangju 61005Republic of Korea Department of Materials Science and Engineering Chonnam National UniversityGwangju 61186Republic of Korea Department of Chemistry Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Institute for Convergence Research and Education in Advanced Technology(I-CREATE) Yonsei UniversitySeoul 03722Republic of Korea Department of Chemistry Xi’an Jiaotong-Liverpool UniversitySuzhou 215123JiangsuChina

Photoelectrochemical(PEC)H_(2)O_(2)production through water oxidation reaction(WOR)is a promising strategy,however,designing highly efficient and selective photoanode materials remains challenging due to competitive reaction ***,for highly enhanced PEC H_(2)O_(2)production,we present a conformal amorphous titanyl phosphate(a-TP)overlayer on nanoparticulate TiO_(2)surfaces,achieved via lysozyme-molded in-situ surface *** a-TP overlayer modulates surface adsorption energies for reaction intermediates,favoring WOR for H_(2)O_(2)production over the competing O_(2)evolution *** density functional theory calculations reveal that a-TP/TiO_(2)exhibits a substantial energy uphill for the O·*formation pathway,which disfavors O_(2)evolution but promotes H_(2)O_(2)***,the a-TP overlayer strengthens the built-in electric field,resulting in favorable ***,a-TP/TiO_(2)exhibits 3.7-fold higher Faraday efficiency(FE)of 63%at 1.76 V *** hydrogen electrode(RHE)under 1 sun illumination,compared to bare TiO_(2)(17%),representing the highest FE among TiO_(2)-based WOR H_(2)O_(2)production *** the a-TP overlayer constitutes a promising strategy for controlling reaction pathways and achieving efficient solar-to-chemical energy conversion.

关键词： Solar H_(2)O_(2) production In-situ surface reforming Titanyl phosphate Amorphous overlayer Reaction pathway control

Relationship between early structural changes at cornea incision sites and surgical outcomes after phacoemulsification

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International Journal of Ophthalmology(English edition) 2019年第7期12卷 1139-1145页

作者： Kyung Hyun Jin tae Gi kim Department of Ophthalmology Kyung Hee University Medical Center Kyung Hee University Seoul 02447 Korea Department of Ophthalmology Kyung Hee University Hospital at Gangdong Kyung Hee University Seoul 05278 Korea

AIM: To assess the early structural changes at clear corneal cataract incision sites and surgical outcomes using anterior segment optical coherence tomography(AS-OCT).METHODS: We evaluated 80 eyes of 59 patients who underwent phacoemulsification with a clear corneal incision. All incisions were evaluated 1 wk, 1, and 3 mo postoperatively using AS-OCT and analyzed regarding angle, length of the incision, maximal corneal thickness at the incision, and if present, corneal endothelial gap length and incision gap area. The patients were divided into two groups according to whether or not an endothelial gap was present at 1 wk postoperatively(endothelial gap, group 1;no endothelial gap, group 2). We analyzed the difference in patient and surgical factors between the two groups, and compared the surgical outcome and the refractive ***: An endothelial gap was observed in 56(70.0%) of 80 eyes at 1 wk postoperatively but not at 3 mo postoperatively. The mean patient age was significantly higher in group 1 than in group 2. The longer the length of the corneal incision and the steeper the incision angle, the greater the length and area of the endothelial gap. In group 1, the mean change in mean keratometry of the anterior cornea was significantly greater than in group 2, and the spherical equivalent(SE) and mean numerical error indicated significant myopic changes at 1 wk postoperatively. CONCLUSION: The risk of an endothelial gap increases with patient age and a long corneal incision and steep incision angle. The presence of an endothelial gap aftersurgery may affect the early postoperative corneal curvature and SE.

关键词： corneal incision structure phacoemulsification corneal curvature corneal endothelial gap anterior segment optical coherence tomography

Microstructure and Tensile Behavior of a Nano-Structured Al-Fe Based Alloy

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Journal of Rare Earths 2004年第Z2期22卷 65-68页

作者： Won-Yong kim Jae-Sung Park Mok-Soon kim tae-Yeub Ra Advanced Materials R&D Center Korea Institute of Industrial Technology # 472Kajwa-dongSuh-guIncheon 404-254Korea School of Materials Science and EngineeringInha University # 253Yonghyun-dongNam-guIncheon 402-751Korea School of Materials Science and EngineeringInha University # 253Yonghyun-dongNam-guIncheon 402-751Korea Advanced Materials R&D CenterKorea Institute of Industrial Technology # 472Kajwa-dongSuh-guIncheon 404-254Korea

Room temperature deformation behavior of A1-8Fe-2Mo-2V-1Zr alloy produced by spray forming and subsequent warm-extrusion at 693 K and/or rolling at 423 K was investigated in terms of tensile test and microstructural *** the specimen processed by spray forming and warm extrusion, the microstructure consisting of equiaxed grains with the average grain size of 500 nm in the matrix phase and uniformly dispersed fine intermetallic A13(Fe, Mo, V, Zr) and A16(Fe, Mo, V, Zr) phases less than 100 nm was characterized. It was revealed that subsequent warm rolling after warm extrusion promotes precipitation of a fine dispersoid from the supersaturated matrix phase. Warm rolling was found to be effective to increase the yield and tensile strength in the high strain rate regime. Elongation of the warm rolled specimen showed highe r value than extruded specimen over the whole strain rate region studied.

关键词： microstructure tensile deformation A1-Fe based alloy spray forming extrusion warm rolling precipitation strain rate sensitivity