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Journal of Animal Science and Biotechnology 2024年第3期15卷 1119-1130页

作者： tae hong kang Sang In Lee Department of Animal Science and Biotechnology Kyungpook National UniversitySangjuGyeong‑Sangbuk‑Do 37224Republic of Korea Research Institute for Innovative Animal Science Kyungpook National University37224SangjuGyeong‑Sangbuk‑DoRepublic of Korea

Background Deoxynivalenol(DON)is a mycotoxin that has received recognition worldwide because of its ability to cause growth delay,nutrient malabsorption,weight loss,emesis,and a reduction of feed intake in *** DON-contaminated feedstuff is absorbed in the gastrointestinal tract,we used chicken organoids to assess the DON-induced dysfunction of the small *** We established a culture system using chicken organoids and characterized the organoids at passages 1 and *** confirmed the mRNA expression levels of various cell markers in the organoids,such as KI67,leucine-rich repeat containing G protein-coupled receptor 5(Lgr5),mucin 2(MUC2),chromogranin A(CHGA),cytokeratin 19(CK19),lysozyme(LYZ),and microtubule-associated doublecortin-like kinase 1(DCLK1),and compared the results to those of the small *** results showed that the organoids displayed functional similarities in permeability compared to the small *** damaged the tight junctions of the organoids,which resulted in increased *** Our organoid culture displayed topological,genetic,and functional similarities with the small intes-tine *** on these similarities,we confirmed that DON causes small intestine *** organoids offer a practical model for the research of harmful substances.

关键词： Barrier function Deoxynivalenol Organoids

Steel-refractory reactions in lanthanum-,cerium-,and ytrium-added steels

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Journal of Iron and Steel Research(International) 2024年第6期31卷 1473-1485页

作者： Jian kang hong-po Wang Yu Wang College of Materials Science and Engineering Chongqing UniversityChongqing 400044China The State Key Laboratory of Mechanical Transmissions Chongqing UniversityChongqing 400044China

A systematic experimental study was conducted on the similarities and differences in the reactions between commonly used rare earth elements(REEs)and frequently used refractories in the steelmaking *** results indicate that the reaction behaviors of La,Ce,and Y with MgO,Al_(2)O_(3),and MgO·Al_(2)O_(3) crucibles differed *** consumption rates of La,Ce,and Y in the molten steel were in descending order of La>Ce>Y for smelting with all three kinds of *** the REEs reacted with the crucible,the contents of Mg and Al showed a trend of first increasing and then *** laboratory-scale smelting conditions,the reactions related to REEs were dominated by steel-crucible reactions,and the contact area between the unit mass of molten steel and refractory materials mainly determined the consumption rates of ***-and Ce-crucible reactions generated loose and porous reaction interfaces;however,Y-crucible reactions generated a dense Y_(2)O_(3) layer,dramatically suppressing the consumption rate of *** calculation indicated that the reactions between rare earth and different refractory materials were first-order *** crucible materials significantly affected the product type and morphology of the steel-crucible reaction interfaces,thereby influencing the consumption rate of *** reactions between REEs and refractories must be seriously considered,especially for small-scale smelting.

关键词： Rare earth Inclusion Refractory Thermodynamics Dynamics

Evaluation of internal void related defects in reinforced concrete slab using electromagnetic wave properties

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 525-535页

作者： Minju kang Jinyoung hong taemin Lee Doyun Kim Hajin Choi School of Architecture Soongsil UniversitySeoul 06978Republic of Korea

This study aims to develop a damage-detection algorithm based on the electromagnetic wave properties inside a reinforced concrete *** proposed method involves employing two algorithms based on data measured using ground-penetrating radar—a common electromagnetic wave method in civil *** possible defect area was identified based on the energy dissipated by the damage in the frequency-wavenumber domain,with the damage localized using the calculated relative permittivity of the *** proposed method was verified through a finite difference time-domain-based numerical analysis and a testing slab with artificial *** a result of verification,the proposed method quickly identified the presence of damage inside the concrete,especially for honeycomb-like defects located at the top of the *** study has practical significance in scanning structures over a large area more quickly than other non-destructive testing methods,such as ultrasonic methods.

关键词： GPR concrete defect electromagnetic wave relative permittivity non-destructive testing(NDT)

Heterobimetallic[NiCo]integration in a hydrogenase mimic for boosting light-driven hydrogen evolution in CaTiO_(3)

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Nano Research 2024年第8期17卷 6888-6894页

作者： kang Li Juanji hong Ningning Song Zhanjun Guo Minmin Liang Experimental Center of Advanced Materials School of Materials Science&EngineeringBeijing Institute of TechnologyBeijing 10081China

Light-drive hydrogen production using titanium-based perovskite is one sustainable way to reduce current reliance on fossil fuels,but its wide applications are still limited by high electron−hole recombination and sluggish surface ***,the developments for low-cost and highly efficient co-catalysts remain *** by natural[NiFe]-hydrogenase active center structure,a hydrogenase-mimic,NiCo_(2)S_(4)nanozyme was synthesized,and subsequently decorated onto the CaTiO_(3)to catalyze the hydrogen evolution reaction(HER).Among the following test,CaTiO_(3)with a 15%loading of NiCo_(2)S_(4)nanozyme exhibited the highest HER rate of 307.76μmol·g^(–1)·h^(–1),which is 60 times higher than that of the CaTiO_(3)*** results reveal that NiCo_(2)S_(4)not only significantly increased the charge separation efficiency of the photogenerated carriers,but also substantively lowered the HER activation *** studies show that NiCo_(2)S_(4)readily splits H_(2)O by forming the Ni(OH)-Co intermediate and only Ni in the bimetallic center alters the oxidation state during the HER process in a manner analogous to the[NiFe]-*** contrast to the often-expensive synthetic catalysts that rely on rare elements such as ruthenium and platinum,this study shows a promising way to develop the nature-inspired cocatalysts to enhance the photocatalysts’HER performance.

关键词： hydrogen evolution reaction hydrogenase-mimic nanozyme photocatalyst water-splitting

Tidal effects based on a GUP-induced effective metric

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Communications in Theoretical Physics 2024年第9期76卷 65-74页

作者： Soon-tae hong Yong-Wan Kim Young-Jai Park Center for Quantum Spacetime and Department of Physics Sogang University Department of Physics and Research Institute of Physics and Chemistry Jeonbuk National University Department of Physics Sogang University

In this paper, we study tidal forces in the Schwarzschild black hole, whose metric explicitly includes a generalized uncertainty principle(GUP) effect. We also investigate interesting features of the geodesic equations and tidal effects that are dependent on the GUP parameter αrelated to a minimum length. Then, by solving the geodesic deviation equations explicitly with appropriate boundary conditions, we show that α in the effective metric affects both the radial and angular components of the geodesic equation, particularly near the singularities.

关键词： effective metric generalized uncertainty principle geodesic deviation equation

Insights into the changes in the surface properties of goethite with Ni in the lattice in the presence of salicylhydroxamic acid:Experimental and density functional theory studies

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 665-677页

作者： Levie Mweene Gilsang hong Hee-Eun Jeong Hee-won kang Hyunjung Kim Department of Earth Resources and Environmental Engineering Hanyang University222 Wangsimni-roSeongdong-guSeoul 04763Republic of Korea

Comparative experiments and theoretical analysis of the surface chemistry changes of goethite(GT)and goethite containing Ni(GTN)in the lattice in the presence of salicylhydroxamic acid(SA)were *** was revealed that in the presence of 100 g·t^(-1)of SA,the flotation recovery of GTN and GT increased with increasing pH,achieving a maximum recovery of 98.9%for both minerals at p H 8.3 and decreasing beyond that pH,with GTN having a slightly higher recovery than GT,except at pH *** was further confirmed by the higher complexation energies of GTN···SA(-883.87 kJ·mol^(-1))compared with GT···SA(-604.23 kJ·mol^(-1))resulting from covalent,closed-shell,and conventional hydrogen *** higher adsorption of SA onto GTN relative to GT was due to the formation of aπ-hole in GTN,thereby promoting a higher interaction of the collector with the ***,the presence of Ni in the GT lattice improves and decreases the adsorption and desorption of SA onto and from the mineral,respectively,compared with those onto and from GT.

关键词： nickel goethite adsorption salicylhydroxamic acid recovery

MicroR-9c-5p and novel-mir50 co-target Akt to regulate Lasioderma serricorne reproduction

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Insect Science 2024年第1期31卷 106-118页

作者： Yi Yan Dong-Dong Qin hong Yang kang-kang Xu Can Li Wen-Jia Yang Provincial Key Laboratory for Agricultural Pest Management of Mountainous Region Institute of EntomologyGuizhou UniversityGuiyangChina Guizhou Provincial Key Laboratory for Rare Animal and Economic Insect of the Mountainous Region College of Biology and Environmental EngineeringGuiyang UniversityGuiyangChina

High fecundity is a common characteristic of insect pests which increases the difficulty of population ***/threonine kinase Akt is an indispensable component of the insulin signaling *** of LsAkt severely hinders reproduction in Lasioderma serricorne,a stored product insect ***,the post-transcriptional pathway of LsAkt in *** remains *** study identified 2 binding sites of miR-9c-5p and novel-mir50 in the coding sequences of *** expression profiles of 2 microRNAs(miRNAs)and LsAkt displayed an opposite pattern during the adult *** reporter assay showed that novel-mir50 and miR-9c-5p could downregulate the expression of *** of miR-9c-5p and novel-mir50 by injection of mimics inhibited the expression of LsAkt and reduced oviposition,decreased egg hatchability,and blocked ovarian *** also decreased the expression of genes involved in ovarian development(LsVg and LsVgR)and the nutritional signaling pathway(LsTOR,LsS6K,and Ls4EBP),and reduced the phosphorylation of ***,injection of miR-9c-5p and novel-mir50 inhibitors induced the expressions of LsAkt,LsVg,LsVgR,LsTOR,LsS6K,and Ls4EBP,enhanced Akt phosphorylation level,and accelerated ovarian *** of bovine insulin downregulated the expression of miR-9c-5p and novel-mir50 and upregulated the LsAkt *** also rescued the reproductive development defects associated with miR-9c-5p/novel-mir50 overexpression,forming a positive regulatory loop of insulin *** results indicate that miR-9c-5p/novel-mir50 regulates the female reproduction of *** by targeting Akt in response to insulin *** data also demonstrate the effects of the insulin/miRNA/Akt regulatory axis in insect reproduction.

关键词： Akt insulin Lasioderma serricorne microRNA reproduction

Durable hierarchical phosphorus‐doped biphase MoS_(2)electrocatalysts with enhanced H^(*)adsorption

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Carbon Energy 2024年第4期6卷 104-114页

作者： Yongteng Qian Jianmin Yu Zhiyi Lyu Qianwen Zhang tae Hyeong Lee Huan Pang Dae Joon kang College of Pharmacy Jinhua PolytechnicJinhuaZhejiangChina Department of Physics Sungkyunkwan UniversitySuwonGyeonggi‐doRepublic of Korea International Collaborative Laboratory of 2D Materials for Optoelectronic Science and Technology of Ministry of Education Institute of Microscale OptoelectronicsShenzhen UniversityShenzhenGuangdongChina School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhouJiangsuChina

Phase engineering is an efficient strategy for enhancing the kinetics of electrocatalytic ***,phase engineering was employed to prepare high‐performance phosphorous‐doped biphase(1T/2H)MoS_(2)(P‐BMS)nanoflakes for hydrogen evolution reaction(HER).The doping of MoS_(2)with P atoms modifies its electronic structure and optimizes its electrocatalytic reaction kinetics,which significantly enhances its electrical conductivity and structural stability,which are verified by various characterization tools,including X‐ray photoelectron spectroscopy,high‐resolution transmission electron microscopy,X‐ray absorption near‐edge spectroscopy,and extended X‐ray absorption fine ***,the hierarchically formed flakes of P‐BMS provide numerous catalytic surface‐active sites,which remarkably enhance its HER *** optimized P‐BMS electrocatalysts exhibit low overpotentials(60 and 72 mV at 10 mA cm^(−2))in H_(2)SO_(4)(0.5 M)and KOH(1.0 M),*** mechanism of improving the HER activity of the material was systematically studied using density functional theory calculations and various electrochemical characterization *** study has shown that phase engineering is a promising strategy for enhancing the H*adsorption of metal sulfides.

关键词： 1T/2H MoS_(2) density functional theory electrocatalysts phase engineering phosphorous doping

Aberrant LETM1 elevation dysregulates mitochondrial functions and energy metabolism and promotes lung metastasis in osteosarcoma

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Genes & Diseases 2024年第3期11卷 368-384页

作者： Yulu Shi Quan kang hong Zhou Xiaohan Yue Yang Bi Qing Luo Stem Cell Biology and Therapy Laboratory The Children's Hospital of Chongqing Medical UniversityNational Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChongqing Key Laboratory of PediatricsChongqing 400014China Department of Pediatric Surgery The Children's Hospital of Chongqing Medical UniversityChongqing 400014China

Osteosarcoma is a differentiation-deficient disease,and despite the unique advan-tages and great potential of differentiation therapy,there are only a few known differentia-tion inducers,and little research has been done on their *** differentiation is associated with an increase in mitochondrial content and *** metabolism of some tu-mor cells is characterized by impaired oxidative phosphorylation,as well as up-regulation of aerobic glycolysis and pentose phosphate ***-containing zipper and EF-hand transmembrane protein 1(LETM1)is involved in the maintenance of mitochondrial morphology and is closely associated with tumorigenesis and progression,as well as cancer cell *** found that MG63 and 143B osteosarcoma cells overexpress LETM1 and exhibit abnormalities in mitochondrial structure and *** of LETM1 partially restored the mitochon-drial structure and function,inhibited the pentose phosphate pathway,promoted oxidative phosphorylation,and led to osteogenic *** also inhibited spheroid cell forma-tion,proliferation,migration,and invasion in an in vitro *** LETM1 was knocked down in vivo,there was reduced tumor formation and lung *** data suggest that mitochondria are aberrant in LETM1-overexpressing osteosarcoma cells,and knockdown of LETM1 partially restores the mitochondrial structure and function,inhibits the pentose phosphate pathway,promotes oxidative phosphorylation,and increases osteogenic differentiation,thereby reducing malignant biological behavior of the cells.

关键词： Cancer metabolism Differentiation LETM1 Osteosarcoma Stemness

Ag-GST/HfO_(x)-based unidirectional threshold switching selector with low leakage current and threshold voltage distribution for high-density cross-point arrays

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Rare Metals 2024年第1期43卷 280-288页

作者： Kyoung-Joung Yoo Dae-Yun kang Nahyun Kim Ho-Jin Lee Ta-Hyeong Kim taeho Kim tae Geun Kim School of Electrical Engineering Korea UniversitySeoul 02841Republic of Korea

The use of electrochemical-metallization-based volatile threshold switching selectors in cross-point arrays has been widely explored owing to their high on-off ratios and simple ***,these devices are unsuitable for cross-point architectures because of the difficulty in controlling the random filament formation that results in large fluctuations in the threshold voltage during *** this study,we investigated the unidirectional threshold transition characteristics associated with an Ag/GST/HfO_(x)/Pt-based bilayer selector and demonstrated the occurrence of a low leakage current(<1×10^(-11) A) and low distribution of the threshold voltage(Δ0.11 V).The bilayer structure could control the filament formation in the intermediate state through the insertion of an HfO_(x) tunneling *** stacking a bilayer selector with NiO_(x)based resistive random-access memory,the leakage and programming currents of the device could be significantly *** the crossbar array configuration,we performed equivalent circuit analysis of a one-selector oneresistor(1S1R) devices and estimated the optimal array size to demonstrate the applicability of the proposed *** maximum acceptable crossbar array size of the 1S1R device with the Ag/GST/HfO_(x)/Pt/Ti/NiO_(x)/Pt structure was 5.29×10^(14)(N^(2),N=2.3×10^(7)).

关键词： Selector device Tunneling barrier Threshold switching Sputtering 1S1R Cross-point array