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Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis

World Journal of Gastroenterology 2003年第12期9卷 2791-2795页

作者： Jun-Ho La tae-Wan kim tae-Sik Sung Jeoung-Woo Kang Hyun-Ju kim ⅠI-Suk Yang Department of Physiology College of Veterinary MedicineSeoul National UniversitySeoulRepublic of Korea

AIM:Irritable bowel syndrome(IBS)is a functional bowel disorder characterized by visceral hypersensitivity and altered bowel *** is increasing evidence suggesting the role of inflammation in the pathogenesis of IBS,which addresses the possibility that formerly established rat model of colitis could be used as an IBS model after the inflammation subsided. METHODS:Colitis was induced by intracolonic instillation of 4% acetic acid in male Sprague-Dawley *** extent of inflammation was assessed by histological examination and myeloperoxidase(MPO)activity *** subsidence of colitis,the rats were subjected to rectal distension and restraint stress,then the abdominal withdrawal reflex and the number of stress-induced fecal output were measured, respectively. RESULTS:At 2 days post-induction of colitis,the colon showed characteristic inflammatory changes in histology and 8-fold increase in MPO *** 7 days post-induction of colitis,the histological features and MPO activity returned to *** rats at 7 days post-induction of colitis showed hypersensitive response to rectal distension without an accompaning change in rectal compliance,and defecated more stools than control animals when under ***: These results concur largely with the characteristic features of IBS, visceral hypersensitivity and altered defecation pattern in the absence of detectable disease, suggesting that this animal model is a methodologically convenient and useful model for studying a subset of IBS.

关键词： Acetic Acid Animals Biological Markers Colitis Disease Models, Animal Inflammation Irritable Bowel Syndrome Male Pain Peroxidase Rats Rats, Sprague-Dawley Research Support, Non-U.S. Gov't

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A study on characteristics of shock train inside a shock tube

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Theoretical & Applied Mechanics Letters 2017年第6期7卷 366-371页

作者： Dong Wook kim tae Ho kim Heuy Dong kim Department of Mechanical Engineering Andong National UniversityAndongKorea

Shock tubes are devices which are used in the investigation of high speed and high temperature flow of compressible gas. lnside a shock tube, the interaction between the reflected shock wave and boundary layer leads to a complex flow phenomenon. Initially a normal shock wave is formed in the shock tube which migrates toward the closed end of the tube and that in turn leads to the reflection of shock. Due to the boundary layer interaction with the reflected shock, the bifurcation of shock wave takes place. The bifurcated shock wave then approaches the contact surface and shock train is generated. Till date only a few studies have been conducted to investigate this shock train phenomenon inside the shock tube. For the present study a computational fluid dynamics （CFD） analysis has been performed on a two dimensional axi-symmetric model of a shock tube using unsteady, compressible Navier-Stokes equations. In order to investigate the detailed characteristics of shock train, parametric studies have been performed by varying different parameters such as the shock tube length, diameter, pressure ratio used inside the shock tube.

关键词： Shock tube Reflected shock wave Boundary layer separation Contact surface Shock train

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Tidal effects based on a GUP-induced effective metric

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Communications in Theoretical Physics 2024年第9期76卷 63-72页

作者： Soon-tae Hong Yong-Wan kim Young-Jai Park Center for Quantum Spacetime and Department of Physics Sogang UniversitySeoul 04107Republic of Korea Department of Physics and Research Institute of Physics and Chemistry Jeonbuk National UniversityJeonju 54896Republic of Korea Department of Physics Sogang UniversitySeoul 04107Republic of Korea

In this paper,we study tidal forces in the Schwarzschild black hole,whose metric explicitly includes a generalized uncertainty principle(GUP)*** also investigate interesting features of the geodesic equations and tidal effects that are dependent on the GUP parameterαrelated to a minimum ***,by solving the geodesic deviation equations explicitly with appropriate boundary conditions,we show thatαin the effective metric affects both the radial and angular components of the geodesic equation,particularly near the singularities.

关键词： generalized uncertainty principle geodesic deviation equation effective metric

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Role of adjuvant chemoradiotherapy and chemotherapy in patients with resected gallbladder carcinoma: a multiinstitutional analysis (KROG 19-04)

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Cancer Biology & Medicine 2022年第6期19卷 931-944页

作者： Sung Uk Lee Jinsil Seong tae Hyun kim Jung Ho Im Woo Chul kim Kyubo kim Hae Jin Park tae Gyu kim Youngkyong kim Bae Kwon Jeong Jin Hee kim Byoung Hyuck kim taek-Keun Nam Center for Proton Therapy and Center for Liver and Pancreatobiliary Cancer National Cancer CenterGoyang 10408Korea Department of Radiation Oncology Yonsei Cancer CenterYonsei University College of MedicineSeoul 03722Korea Department of Radiation Oncology CHA Bundang Medical CenterCHA University School of MedicineSeongnam 13497Korea Department of Radiation Oncology Inha University HospitalInha University School of MedicineIncheon 22332Korea Department of Radiation Oncology Ewha Womans University Mokdong HospitalEwha Womans University College of MedicineSeoul 07985Korea Department of Radiation Oncology Hanyang University Medical CenterHanyang University College of MedicineSeoul 04763Korea Department of Radiation Oncology Samsung Changwon HospitalSungkyunkwan University School of MedicineChangwon 51353Korea Department of Radiation Oncology Kyung Hee University HospitalKyung Hee University College of MedicineSeoul 02447Korea Department of Radiation Oncology Gyeongsang National University HospitalGyeongsang National University College of MedicineJinju 52727Korea Department of Radiation Oncology Dongsan Medical CenterKeimyung University School of MedicineDaegu 41931Korea Department of Radiation Oncology Seoul Metropolitan Government Seoul National University Boramae Medical CenterSeoul 07061Korea Department of Radiation Oncology Chonnam National University Hwasun HospitalChonnam National University College of MedicineHwasun 58128Korea

Objective:The effectiveness of adjuvant treatments for resected gallbladder carcinoma(GBC)has remained unclear due to lack of randomized controlled trials;thus,the aim of present study was to evaluate the role of adjuvant treatments,including chemoradiotherapy(CRT)and/or chemotherapy(CTx),in patients with resected ***:A total of 733 GBC patients who received curative-intent surgical resection were identified in a multi-institutional *** 733 patients,372(50.8%)did not receive adjuvant treatment,whereas 215(29.3%)and 146(19.9%)received adjuvant CTx and CRT,*** locoregional recurrence-free survival(LRFS),recurrence-free survival(RFS),and overall survival(OS)of the adjuvant treatment groups were compared according to tumor stage(stage II *** III–IV).Results:In stage II disease(n=381),the 5-year LRFS,RFS,and OS were not significantly different among the no-adjuvant therapy,CTx,and CRT groups,and positive resection margin,presence of perineural invasion,and Nx classification were consistently associated with worse LRFS,RFS,and OS in the multivariate analysis(P<0.05).For stage III–IV(n=352),the CRT group had significantly higher 5-year LRFS,RFS,and OS than the no-adjuvant therapy and CTx groups(67.8%,45.2%,and 56.9%;37.9%,28.8%,and 35.4%;and 45.0%,30.0%,and 45.7%,respectively)(P<0.05).Conclusions:CRT has value as adjuvant treatment for resected GBC with stage III–IV *** study is needed for stage II disease with high-risk features.

关键词： Gallbladder cancer adjuvant treatment chemoradiotherapy locoregional recurrence-free survival overall survival

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Effect of heating rate on the properties of silicon carbide fiber with chemical-vapor-cured polycarbosilane fiber

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Journal of Advanced Ceramics 2017年第1期6卷 59-66页

作者： tae-Eon kim Khos-Erdene KHISHIGBAYAR Kwang Youn CHO Ceramic Fiber and Composite Materials Center Korea Institute of Ceramic Engineering and Technology 101 Soho-ro Jinju-si Gyeongsangnam-do 660-031 R.O.Korea

Silicon carbide (SiC) fiber has recently received considerable attention as promising next-generation fiber because of its high strength at temperatures greater than 1300 ℃ in ***-quality SiC fiber is primarily made through a curing and heat treatment *** this study,the chemical vapor curing method,instead of the thermal oxidation curing method,was used to prepare cured polycarbosilane (PCS) *** the high temperature heat treatment of the cured PCS fiber,varied heating rates of 10,20,30,and 40 ℃/min were *** the process,the fiber remained in the amorphous silicon carbide phase,and the measured tensile strength was the greatest when the oxygen content in the heat-treated fiber was low,due to the rapid heating *** fiber produced through this method was also found to have excellent internal oxidation *** fast,continuous process shows a great promise for the production of SiC fiber and the development of high-quality products.

关键词： polycarbosilane (PCS) silicon carbide (SiC) fiber chemical vapor curing rapid heating rate high temperature tensile strength

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A Study on Energy Saving Rate for Variable Speed Condition of Multistage Centrifugal Pump

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Journal of Thermal Science 2015年第6期24卷 566-573页

作者： Sang-Ho Suh Rakibuzzaman Kyung-Wuk kim Hyoung-Ho kim In Sik Yoon Min-tae Cho Department of Mechanical Engineering Soongsil University Dooch Co. 295 Sagok-ri Jangan- Myeon Hwaseong-si Gyeonggi-do 445-942 South Korea

Centrifugal pumps are being widely used in many industrial and commercial *** of these pumps are being operated at constant speed but could provide energy savings through adjustable speed *** purpose of this study was to get the energy saving rates of the multistage centrifugal pump with variable speed *** this investigation an experimental set up of variable flow and pressure system was made to get energy saving rates and numerical analyses are applied to validate the pump *** energy saving and therefore the cost saving depends on the specific duty cycle of which the machine *** cycle is the proportion of time during which a component,device and system is *** duty cycle segmented into different flow rates and weighting the average value for each segment by the interval *** system was operated at 50%or less of the pump *** input power of the system was carried out by pump characteristics curve of each operating *** energy consumption was done by the product of specific duty cycle and the input power of the system for constant speed and variable speed drive *** total energy consumed for constant speed drive pump was 75,770 k *** and for variable speed drive pump was 31,700 k *** total energy saving of the system was 44,070 k *** or 58.16%***,this paper suggests a method of implementing an energy saving on variable-flow and pressure system of the multistage centrifugal pump.

关键词： Multistage Centrifugal Pump Performance Analysis Energy saving rate SST Model Duty Cycle

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Mooring Tension and Motion Characteristics of A Submerged Fish Reef with Net in Waves and Currents Using Numerical Analysis

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China Ocean Engineering 2012年第2期26卷 261-276页

作者： tae Ho kim David W.Fredriksson Judson DeCewc School of Marine Technology Chonnam National University Department of Naval Architecture and Ocean Engineering United States Naval Academy Annapolis Center for Ocean Engineering University of New Hampshire

A numerical model was used to analyze the motion response and mooring tension of a submerged fish reef system. The system included a net attached to a rigid structure suspended up from the bottom with a single, high tension mooring by fixed flotation. The analysis was performed by using a Morison equation type finite element model configured with truss elements. Input forcing parameters into the model consisted of both regular and irregular waves, with and without a steady current. Heave, surge and pitch dynamic calculations of the reef structure were made. Tension response results of the attached mooring line were also computed. Results were analyzed in both the time and frequency domain in which appropriate, linear transfer functions were calculated. The influence of the current was more evident in the tension and heave motion response data. This is most likely the result of the large buoyancy characteristics of the reef structure and the length of the mooting cable. Maximum mooting component tension was found to be 13.9 kN and occurred when the reef was subjected to irregular waves with a co-linear current of 1.0 m/s velocity. The results also showed that the system had little damping （in heave） with damped natural periods of 2.8 s. This combination of system characteristics promotes a possible resonating situation in typical open sea conditions with similar wave periods.

关键词： floating fish reef fish aggregating device numerical model waves and currents net structure

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Influence of operational parameters on the photocatalytic performance of DE-NOx process Via MIL-101(Fe)

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Progress in Natural Science:Materials International 2018年第6期28卷 689-695页

作者： Hoang Phuc Nguyen tae Ho kim Soo Wohn Lee Research Center for Eco Multi-Functional Nano Materials Sun Moon University Department of Environmental & Bio-Chemical Engineering Sun Moon University

Metal organic framework(MOF)has been paid great attention as a potential candidate for various applications in the field of energy and environment,particularly in air *** various MOFs,MIL-101(Fe) represents an interesting material possessing many advantages,including the ease of fabrication,high porosity,high specific surface area with open metal sites,making it a promising material in the field of harmful gas *** these advantages,MIL-101(Fe) was synthesized by facile microwave-solvothermal method and applied as a photocatalyst for the degradation of *** de-NOxefficiency of the synthesized powder was evaluated with respect to various operating parameters including substrates,sample doses,light spectrum and light intensity,initial NO concentration,and relative *** results have shown that the efficiency of NOxphotocatalytic degradation reaches to 77%under solar irradiation via 0.1 g of MIL-101(Fe) with optimum condition of reaction,(alumina substrate,350 ppb of initial NO concentration,40–50%of relative humidity).Then this work provides the optimum condition for the efficient photocatalytic degradation of NOx.

关键词： Metal-organic framework MIL-101 Gaseous pollutant NOx emission Photocatalyst

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Evaluation of lubrication performance of crank pin bearing in a marine diesel engine

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Friction 2018年第4期6卷 464-471页

作者： Suk Man MOON Yong Joo CHO tae Wan kim School of Mechanical Engineering Pusan National University Department of Mechanical Engineering Pukyong National University

In this study, the lubrication performance of the crank pin bearing in a marine two–stroke diesel engine is evaluated to investigate the adhesional failure on the crank pin bearing. A numerical algorithm for the lubrication analysis considering motion analysis of the crank pin system is developed. The film pressure and thickness for three clearances and three lubricant temperatures are calculated. The results show that the lubricant temperature has a higher effect on film thickness than clearance. In terms of the film parameter, the operating condition that can result in solid–solid contact is investigated. We also suggest the desirable operating conditions of clearance and lubricant temperature to prevent the solid–solid contact.

关键词： crank pin bearing film thickness lubricant film parameter diesel engine

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Effects of planting distance and depth on PTO load spectrum of a small riding-type transplanter

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International Journal of Agricultural and Biological Engineering 2020年第2期13卷 57-63页

作者： Wan-Soo kim Yeon-Soo kim taek-Jin kim Kyu-Chul Nam tae-Bum kim tae-Ho Han Ryu-Gap Im Yong-Hyeon kim Yong-Joo kim Department of Biosystems Machinery Engineering Chungnam National UniversityDaejeon 34134Republic of Korea Department of Smart Agriculture Systems Chungnam National UniversityDaejeon 34134Republic of Korea Convergence Agricultural Machinery Group Korea Institute of Industrial TechnologyGimje 54325Republic of Korea Certification WarrantyInspection and Standardization TeamKorea Agricultural Machinery Industry CooperativeCheonan 31041Republic of Korea Diesel Service Korea Co.Ltd. Daejeon 34357Republic of Korea Agricultural Machinery Certification Team Foundation of Agricultural Technology Commercialization and TransferIksan 54667Republic of Korea Gint Co.Ltd. Suwon 16225Republic of Korea

The aim of this study was to analyze the effects of the planting distance and depth on the power take-off(PTO)load spectrum of a small riding-type transplanter for the optimal design of the *** measure load data during actual planting operation,a load measurement system was developed using a torque sensor,a data acquisition system,and an *** experiments were conducted at four planting distances(26 cm,35 cm,43 cm,and 80 cm)and three planting depths(85 mm,105 mm,and 136 mm)in a field with similar soil *** measured load data were inverted into a load spectrum using rain-flow counting and Smith-Watson-Topper(SWT)*** safety factor of a transplanter according to the planting conditions was analyzed using the converted load spectrum and commercial *** load spectrum for all planting conditions showed torque ratios similar within a high cycle region of 108 to *** torque ratio increased when the planting depth increased and planting distance decreased in the low cycle region under less than 108 *** safety factors of the PTO driving gear and the driven gear increased as the planting distance increased at all planting *** the planting depth decreased at the same planting distance,the safety factor of the PTO gears *** results of this study might provide useful information for a transplanter PTO design considering the working load according to the various planting conditions.

关键词： transplanter planting distance planting depth power take-off load spectrum safety factor

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