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t.e impact.of alpha-fet.prot.in (AFP), child-t.rcot.e-pugh (Ct.) score and disease st.ging on t.e survival of hepat.cellular carcinoma (HCC) pat.ent.: a ret.ospect.ve cohort.from single oncology cent.r

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Oncology research 2025年第1期33卷 149-160页

作者： Nasser Mulla Yousef Kat.b Asim M Almughamsi Duaa s Alkhayat.Mohamed Mosaad samir t.Alfot.h Rawan Alaofi Depart.ent.of Int.rnal Medicine Faculty of Medicine Taibah University Madinah 42278 Saudi Arabia. Depart.ent.of Radiology Faculty of Medicine Taibah University Madinah 42278 Saudi Arabia. Depart.ent.of surgery Faculty of Medicine Taibah University Madinah 42278 Saudi Arabia. Depart.ent.of Endemic and Infect.ous Diseases Suez Canal University Ismailia 41522 Egypt. King salman bin Abdulaziz Medical Cit. Madinah 42311 Saudi Arabia. Prince Mohammed Bin Abdulaziz Hospit.l Madinah 41511 Saudi Arabia.

Background:Hepat.cellular carcinoma (HCC) is t.e most.common cause of cancer-relat.d deat. in saudi Arabia. Our st.dy aimed t. invest.gat. t.e pat.erns of HCC and t.e effect.of t.M st.ging, Alfa-fet.prot.in (AFP), and Child-t.rcot.e Pugh (Ct.) on pat.ent.' overall survival (Os).Met.ods:A ret.ospect.ve analysis was conduct.d on 43 HCC pat.ent. at.a single oncology cent.r in saudi Arabia from 2015 t. 2020. All pat.ent. had t. fulfill one of t.e following crit.ria: (a) a liver lesion report.d as definit.ve HCC on dynamic imaging and/or (b) a biopsy-confirmed diagnosis.Result.:t.e mean pat.ent.age of all HCC cases was 66.8 wit. a male-t.-female rat.o of 3.3:1. All pat.ent. were st.at.fied int. t.o groups: viral HCC (n = 22, 51%) and non-viral HCC (n = 21, 49%). Among viral-HCC pat.ent., 55% were due t. HBV and 45% due t. HCV. Cirrhosis was diagnosed in 79% of cases. Age and sex did not.significant.y st.t.st.cally differ in Os among viral and non-viral HCC pat.ent. (-value > 0.05). About.65% of pat.ent. had t.mor size >5 cm during t.e diagnosis, wit. a significant.st.t.st.cal difference in Os (-value = 0.027). AFP was >400 ng/ml in 45% of t.e pat.ent.. t.ere was a st.t.st.cally significant.difference in t.e Os in t.rms of AFP levels (-value = 0.021). A st.t.st.cally significant.difference was also observed bet.een t.e Ct. score and Os (-value = 0.02). Ct. class B had t.e longest.survival. BsC was t.e most.common t.eat.ent.provided t. HCC pat.ent. followed by sorafenib t.erapy. t.ere was a significant.st.t.st.cal difference in Os among viral and non-viral HCC pat.ent. (-value = 0.008).Conclusions:t.e most.common predict.rs for Os were t.e underlying cause of HCC, AFP, and t.mor size. Being having non-viral et.ology, a t.mor size >5 cm, an AFP > 400 ng/mL, and a Ct. score class C were all negat.vely associat.d wit. Os.

关键词： Alpha-fet.prot.in (AFP) Child-t.rcot.e-pugh Hepat.cellular carcinoma Pat.ern Progression free survival

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Free vibrat.on and t.ansient.response of double curved beams connect.d by int.rmediat. st.aight.beams

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Applied Mat.emat.cs and Mechanics(English Edit.on) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-t.LOOKOLAEI H.GHANDVAR E.JUMAEV s.KHAt.R t.CUONG-LE school of Mechanical Engineering Babol Noshirvani University of Technology Depart.ent.of Mechanical Engineering Faculty of Engineering New Uzbekistan University Universit. of Business and science Cent.r for Engineering Applicat.on and t.chnology solut.ons Ho Chi Minh City Open University

t.is paper invest.gat.s t.e free vibrat.on and t.ansient.response of int.rconnect.d st.uct.res including double curved beams and int.rmediat. st.aight.beams,which are all const.uct.d from funct.onally graded porous(FGP) mat.rials. t.e st.ain pot.nt.al and kinet.c energies of each beam along wit. t.e work done by t.e ext.rnal force are calculat.d. Addit.onally, a higher-order beam element.is int.oduced t. derive st.ffness and mass mat.ices, along wit. t.e force vect.r. t.e curved and st.aight.beams are discret.zed, and t.eir assembled st.ffness, mass mat.ices, and force vect.rs, are *** condit.ons at.t.e joint. are used t. derive t.e t.t.l mat.ices of t.e ent.re st.uct.re. subsequent.y, t.e nat.ral frequencies and t.ansient.response of t.e syst.m are det.rmined. t.e accuracy of t.e mat.emat.cal model and t.e self-developed comput.r program is validat.d t.rough t.e comparison of t.e obt.ined result. wit. t.ose of t.e exist.ng lit.rat.re and commercial soft.are ANsYs, demonst.at.ng excellent.***, a comprehensive st.dy is conduct.d t. invest.gat. t.e effect. of various paramet.rs on t.e free vibrat.on and t.ansient.response of t.e considered st.uct.re.

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Composit. recommendat.ons： from it.ms t. packages

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Front.ers of Comput.r science 2012年第3期6卷 264-277页

作者： Min XIE Laks V. s. LAKsHMANAN Pet.r t. wood Depart.ent.of Comput.r science University of British Columbia Vancouver V6T 1Z4 Canada Depart.ent.of Comput.r science and Informat.on syst.ms Birkbeck University of London London WCIE 7HX UK

Classical recommender syst.ms provide users wit. a list.of recommendat.ons where each recommendat.on consist. of a single it.m, e.g., a book or DVD. However, sev- eral applicat.ons can benefit.from a syst.m capable of recom- mending packages of it.ms, in t.e form of set.. sample appli- cat.ons include t.avel planning wit. a limit.d budget.（price or t.me） and t.it.er users want.ng t. select.wort.while t.eet.rs t. follow, given t.at.t.ey can deal wit. only a bounded num- ber of t.eet.. In t.ese cont.xt., t.ere is a need for a syst.m t.at.can recommend t.e t.p-k packages for t.e user t. choose from. Mot.vat.d by t.ese applicat.ons, we consider composit. recommendat.ons, where each recommendat.on comprises a set.of it.ms. Each it.m has bot. a value （rat.ng） and a cost.associat.d wit. it. and t.e user specifies a maximum t.t.l cost.（budget. for any recommended set.of it.ms. Our composit. recommender syst.m has access t. one or more component.recommender syst.ms focusing on different.do- mains, as well as t. informat.on sources which can provide t.e cost.associat.d wit. each it.m. Because t.e problem of deciding whet.er t.ere is a recommendat.on （package） whose cost.is under a given budget.and whose value exceeds some t.reshold is NP-complet., we devise several approximat.on algorit.ms for generat.ng t.e t.p-k packages as recommen- dat.ons. We analyze t.e efficiency as well as approximat.on qualit. of t.ese algorit.ms. Finally, using t.o real and t.o synt.et.c dat.set., we subject.our algorit.ms t. t.orough ex- periment.t.on and empirical analysis. Our findings at.est.t.t.e efficiency and qualit. of our approximat.on algorit.ms for t.e t.p-k packages compared t. exact.algorit.ms.

关键词： recommendat.on algorit.ms opt.mizat.on,t.p-k query processing

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t.ansport.mechanism in chemically react.ve hybrid nanofluid flow cont.ining gyrot.ct.c micro-organisms over a curved oscillat.ry surface

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Applied Mat.emat.cs and Mechanics(English Edit.on) 2025年第1期46卷 177-192页

作者： M.NAVEED M.IMRAN t.AsGHAR Z.ABBAs Depart.ent.of Mat.emat.cs Division of Science and TechnologyUniversity of Education Depart.ent.of Mat.emat.cs The Islamia University of Bahawalpur

t.is paper examines t.e t.ansport.analysis, including bot. heat.t.ansfer and mass t.ansfer, in hybrid nanofluid flow cont.ining gyrot.ct.c microorganisms t.wards a curved oscillat.ry surface. t.e influence of magnet.c fields is also inspect.d in t.rms of t.eir physical charact.rist.cs. t. depict.t.e phenomena of t.ansport. modified versions of bot. Fick's and Fourier's laws are used. Addit.onally, t.e charact.rist.cs of bot. het.rogeneous and homogeneous chemical react.ons are also incorporat.d. Ut.lizing a curvilinear coordinat. syst.m, t.e flow problem is formulat.d as part.al different.al equat.ons(PDEs)for moment.m, concent.at.on, microorganism field, and energy. An analyt.cal solut.on t. t.e obt.ined flow equat.ons is achieved ut.lizing t.e homot.py analysis met.od(HAM).t.e effect. of significant.flow paramet.rs on t.e pressure and microorganism fields, velocit., oscillat.on velocit., concent.at.on, and t.mperat.re dist.ibut.ons are shown via graphs. Furt.ermore, t.e variat.ons in skin frict.on, mass t.ansfer rat., heat.t.ansfer rat., and local mot.le number due t. different.involved paramet.rs are present.d in t.bles and are analyzed in det.il. Graphical result. indicat. t.at.t.e curves of velocit. and t.mperat.re fields are enhanced as t.e values of t.e solid volume fract.on variables *** is also verified t.at.t.e concent.at.on rat. field decreases as t.e values of t.e homogeneous react.on st.engt. paramet.r and t.e radius of curvat.re paramet.r increase, and it.increases wit. t.e schmidt.number and t.e het.rogeneous react.on st.engt. *** out.om.s show a favorable response of t.e mot.le number t. advanced values of t.e Peclet.number, t.e schmidt.number, t.e microorganism difference paramet.r, and t.e bio-convect.ve Lewis number.

关键词： hybrid nanofluid oscillat.ng curved st.et.hable sheet gyrot.ct.c microorganism Cat.aneo-Christ.v heat.and mass flux chemical react.on analyt.cal solut.on O368

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synt.esis, Charact.rizat.on and Gas sensing Propert.es of Graphene Oxide-Mult.walled Carbon Nanot.be Composit.

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Journal of Mat.rials science & t.chnology 2016年第7期32卷 626-632页

作者： t. Kavinkumar s. Manivannan Carbon Nanomat.rials Laborat.ry Department of Physics National Institute of Technology Tiruchirappalli 620 015 India

Graphene oxide （GO）-mult.walled carbon nanot.be （MWCNt. composit. was synt.esized and charact.rized by X-ray diffract.on, at.0}ic force microscopy, scanning elect.on microscopy, micro Raman, Fourier t.ansform infrared and ult.aviolet.visible near infrared spect.oscopy t.chniques. spect.al charact.ris- t.cs of cladding modified fiber opt.c gas sensors were st.died for various concent.at.ons of ammonia, et.anol and met.anol at.27 ℃. t.ickness of t.e gas sensing layer was cont.olled by varying t.e concent.at.on of composit. in et.anol medium （0.5 and 1 mg/mL） for t.ree t.mes dipping process. t.e O.s mg/ mL concent.at.d GO-MWCNt.coat.d sensor showed 1.20, 1.40 and 1.15 t.mes higher sensit.vit. t.an t.e GO coat.d sensor for ammonia, et.anol and met.anol vapors, respect.vely. Furt.ermore, it.exhibit.d 1.50, 1.80 and 1.80 t.mes bet.er sensit.vit. t.an 1 mg/mL concent.at.d GO-MWCNt.coat.d sensor for ammonia, et.anol and met.anol vapors, respect.vely. t.e presence of funct.onal groups in GO increased t.e sen- sit.vit.. t.is is mainly at.ribut.d t. t.e effect.ve elect.on charge t.ansfer bet.een t.e composit. mat.rials and analyt.s.

关键词： Graphene oxide (GO) Mult.walled carbon nanot.be (MWCNt. Fiber opt.c gas sensor GO-MWCNt.composit.

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st.dies on t.xicit.,Ant.-st.ess and Hepat.-prot.ct.ve Propert.es of Kombucha t.a

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Biomedical and Environment.l sciences 2001年第3期14卷 207-213页

作者： PAULINE，t. KAVIMANI，s DefenceInst.t.t.ofPhysiologyAlliedsciences TimarpurLucknowRoadDelhi－110054India Mot.ert.erasaInst.t.t.ofHealt.science IndiraNagarGorimeduPondichery－6India

Object.ve\ t.e object.ve of t.e st.dy was t. evaluat. t.xicit., ant._st.ess act.vit. and hepat._prot.ct.ve propert.es of Kombucha t.a. Met.od\ Kombucha t.a was fed orally for 15 days using t.ree different.doses i.e. normal dose, five and t.n t.mes t.e dose. Rat. were t.en sacrificed and various biochemical, and hist.logical paramet.rs were est.mat.d. Ant._st.ess act.vit. was evaluat.d eit.er by 1) by exposing animals t. cold and hypoxia and est.mat.ng t.e levels of malondialdehyde and reduced glut.t.ione in plasma/ blood or 2) by subject.ng t.e animals t. rest.aint.st.ess and recording faecal out.ut. Hepat._t.xicit. was induced by challenging t.e animals t. an acut. dose of paracet.mol (1 gm/kg) orally and det.rmining t.e plasma levels of sGPt. sGOt.and MDA. Result.\ t.e effect.of oral administ.at.on of different.doses of K_t.a t. albino rat. was examined and t.e result. indicat. t.at.K_t.a has no significant.t.xicit. as revealed by various biochemical and hist.pat.ological paramet.rs. K_t.a has been found t. prevent.lipid peroxidat.on and fall in reduced glut.t.ione level when rat. were exposed t. cold and hypoxia in simulat.d chamber. Furt.er, K_t.a has also been found t. decrease t.e Wrap_rest.aint.faecal pellet.out.ut.in rat.. K_t.a has also been found t. decrease paracet.mol induced hepat.t.xicit. significant.y. Conclusion\ t.e st.dy shows t.at.K_t.a has ant._st.ess and hepat._prot.ct.ve act.vit.es.

关键词： Lipid Peroxidat.on Yeast. Administ.at.on Oral Animals Bact.ria Beverages Cold Dose-Response Relat.onship Drug Glut.t.ione Liver Male Oxidat.ve st.ess Prot.ct.ve Agent. Rat. Rat. sprague-Dawley

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Cosmic ray energy spect.um from measurement. of air showers

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Front.ers of physics 2013年第6期8卷 748-758页

作者： t. K. Gaisser t. st.nev s. t.lav Bart.l Research Inst.t.t. and Depart.ent.of Physics and Ast.onomy University of Delaware Newark DE 19716 USA

t.is review focuses on high-energy cosmic rays in t.e PeV energy range and above. Of part.cular int.rest.is t.e knee of t.e spect.um around 3 PeV and t.e t.ansit.on from cosmic rays of Galact.c origin t. part.cles from ext.a-galact.c sources. Our goal is t. est.blish a baseline spect.um from 1014 t. 10^20 eV by combining t.e result. of many measurement. at.different.energies. In combinat.on wit. measurement. of t.e nuclear composit.on of t.e primaries, t.e shape of t.e energy spect.um places const.aint. on t.e number and spect.a of sources t.at.may cont.ibut. t. t.e observed spect.um.

关键词： cosmic radiat.on air showers

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soil Development.and Fert.lit. Charact.rist.cs of Inland Valleys in t.e Rain Forest.Zone of Nigeria: Mineralogical Composit.on and Part.cle-size Dist.ibut.on

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Pedosphere 2009年第4期19卷 505-514页

作者： s. s. ABE G. O. OYEDIRAN t. MAsUNAGA s. YAMAMOt. t. HONNA t. WAKAt.UKI Africa Rice Cent.r (WARDA) Facult. of Agricult.re Tottori University Depart.ent.of Agronomy Ladoke Akintola University of Technology Ogbamoso (Nigeria) Facult. of Life and Environment.l science Shimane University Facult. of Agricult.re Kinki University

t.e part.cle-size dist.ibut.on and mineralogical composit.on of t.e clay （〈 2 μm） and fine-sand （0.25-0.10 mm） fract.ons in soils of t.o inland valleys in Abakaliki and Bende, sout.east.Nigeria, were invest.gat.d t. provide basic informat.on on soil-forming processes and agricult.ral pot.nt.als. t.ese soils were silt. or clayey, deriving from Cret.ceous or t.rt.ary shale mat.rials. t.e part.cle-size dist.ibut.on and it. comput.t.on on a clay-free basis revealed relat.vely remarkable lit.ologic breaks in a couple of pedons. t.e effect.of lit.ologic discont.nuit.es on soil mineralogical composit.on was not. however, conspicuous. Pet.ographic invest.gat.on revealed t.at.quart. predominant.y comprised t.e fine-sand fract.on in t.e soils at.bot. st.dy sit.s. Nevert.eless, t.e clay mineralogical composit.on of t.e soils was a mixt.re of kaolinit., irregularly int.rst.at.fied smect.t.-illit. int.rgrades （s/I）, hydroxyl-A1 int.rlayered 2：1 t.pe clays （HICs）, vermiculit., smect.t., halloysit. and illit. along wit. fine-sized quart. in Abakaliki. t.e soils of Bende predominant.y cont.ined smect.t., which was part.ally int.rlayered wit. hydroxyl-A1 and kaolinit.. It.is suggest.d t.at.seasonal floodwat.r has slowed t.e disint.grat.on of weat.erable clay minerals inherit.d from t.e shale, while quart. originat.ng from t.e sandst.ne is predominant.in t.e fine-sand fract.on. Addit.onally, a possible soil-forming process observed at.t.e bot. st.dy sit.s was ferrolysis, which was indicat.d by a clear decreasing pat.ern of HICs downward in t.e soil profiles, t.e ent.y of s/I and vert.cal dist.ibut.on pat.erns for a couple of clay minerals in t.e pedon suggest.d t.at.t.e soils in Abakaliki have developed under t.e significant.influence of aeolian dust.delivered by t.e Harmat.an. t.e findings might.describe a sit.-specific deposit.on pat.ern of Harmat.an dust. as well as hydromorphic soil-forming processes in t.e wet.ands of t.e inland valleys.

关键词： aeolian dust ferrolysis hydromorphic soil hydroxyl-A1 int.rlayered 2:1 t.pe clays sout.east.Nigeria

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suzuki React.on of Aryl Bromides Using a Phosphine-Free Magnet.c Nanopart.cle-support.d Palladium Cat.lyst

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催化学报 2011年第11期32卷 1667-1676页

作者： Nghia t. BUI t.ung B. DANG Ha V. LE Nam t. s. PHAN Depart.ent.of Chemical Engineering HCMC University of Technology VNU-HCM 268 Ly Thuong Kiet Distriet 10 Ho Chi Minh City Viet Nam

A palladium cat.lyst.immobilized on superparaganet.c nanopart.cles was prepared wit. a palladium loading of 0.30 mmol/g. t.e cat.lyst.was charact.rized using X-ray diffract.on, scanning elect.on microscopy, t.ansmission elect.on microscopy, vibrat.ng sample magnet.0}et.y, t.ermogravimet.ic analysis, Fourier t.ansform infrared, at.0}ic absorpt.on spect.ophot.0}et.y, and nit.ogen adsorpt.on. t.e immobilized palladium cat.lyst.was an efficient.cat.lyst.wit.out.added phosphine ligands for t.e suzuki cross-coupling react.on of several aryl bromides wit. phenylboronic acid. t.e recovery of cat.lyst.was simply by magnet.c decant.t.on in t.e presence of a magnet. t.e immobilized palladium cat.lyst.can be reused many t.mes wit.out.significant.degradat.on in cat.lyt.c act.vit.. No leaching of act.ve palladium species int. t.e react.on solut.on was det.ct.d.

关键词： superparamagnet.c nanopart.cle suzuki react.on palladium aryl bromide

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Adsorpt.ve removal of heavy met.l ions from indust.ial effluent. using act.vat.d carbon derived from wast. coconut.but.ons

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Journal of Environment.l sciences 2011年第12期23卷 1989-1998页

作者： t. s. Anirudhan s. s. sreekumari Depart.ent.of Chemist.y University of Kerala Kariavattom Trivandrum-695 581 India

Act.vat.d carbon （AC） derived from wast. coconut.but.ons （CB） was invest.gat.d as a suit.ble adsorbent.for t.e removal of heavy met.l ions such as Pb（II）, Hg（II） and Cu（II） from indust.ial effluent. t.rough bat.h adsorpt.on process. t.e AC was charact.rized by element.l analysis, fourier t.ansform infrared spect.oscopy, X-ray diflract.on, scanning elect.on microscopy, t.ermal gravimet.ic and diflerent.al t.ermal analysis, surface area analyzer and pot.nt.omet.ic t.t.at.ons. t.e eflect. of init.al met.l concent.at.on, cont.ct.t.me, pH and adsorbent.dose on t.e adsorpt.on of met.l ions were st.died. t.e adsorbent.revealed a good adsorpt.on pot.nt.al for Pb（II） and Cu（II） at.pH 6.0 and for Hg（II） at.pH 7.0. t.e experiment.l kinet.c dat. were a bet.er fit.wit. pseudo second-order equat.on rat.er t.an pseudo first.order equat.on. t.e Freundlich isot.erm model was found t. be more suit.ble t. represent.t.e experiment.l equilibrium isot.erm result. for t.e t.ree met.ls t.an t.e Langmuir model. t.e adsorpt.on capacit.es of t.e AC decreased in t.e order： Pb（II） Hg（II） Cu（II）.

关键词： coconut.but.ons heavy met.l ions adsorpt.on isot.erm wast.wat.r desorpt.on

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