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Cholinesterase Activity as an Indicator of Health Risks among Kou Valley Farmers

Journal of Biosciences and Medicines 2024年第7期12卷 71-86页

作者： t.iombiano cherileila Hien S. Aristide Koevi Nadège Bayili Bazoma Ouattara Abdoulaye traore Patrice traore t. Isidore Hien Herve Centre Muraz Institut National de Sant Publique (INSP) Bobo-Dioulasso Burkina Faso Institut Suprieur des Science de la Sant (INSSA) University of Nazi Boni Bobo-Dioulasso Burkina Faso Institut de Recherche en Science de la Sant (IRSS) Centre National de Recherche Scientifique et Technologique (CNRST) Ouagadougou Burkina Faso

Introduction: Pesticides are currently an essential component of agricultural production techniques for controlling pests and weeds. In Burkina Faso, non-compliance with good practice in the use of pesticides poses a real health problem for the population. this study examines the health risks associated with pesticide management in rice-growing areas. Material and Methods: A field survey was conducted in Bama, involving farmers, focusing on their socio-demographic characteristics, pesticide usage, and health effects. Cholinesterase levels were measured in subsample of farmers using a portable device. Data were analysed using Microsoft Excel, calculating means and percentages for various practices. Health consultations, protection methods, and pesticide management were studied. Erythrocyte acetylcholinesterase activity was compared before and after treatment. Data were categorised into classes based on inhibition levels, and correlation analyses determined relationships between variables such as age, years of experience, and cholinesterase activity. Results: the results indicate that rice cultivation is mainly carried out by a fairly young population, with nearly 63% being under the age of 50. Common poor practices in pesticide use include improper storage and reuse of leftover pesticides. Seven types of pesticides were identified, including organophosphates such as glyphosate, which was used in 26.7% of cases. this organophosphate has resulted in class B poisoning, causing a 30% - 50% reduction in erythrocyte cholinesterase activity. the health effects of pesticide use are felt by agricultural farmers through various symptoms of poisoning. Conclusion: to reduce the occurrence of pesticide poisoning, it is essential to launch information and awareness campaigns among the population and farmers to promote safe practices in pesticide use in Bama, Burkina Faso.

关键词： Pesticides Environmental Sanitary Risk Acetylcholinesterase Farmers Bama Burkina Faso

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Ionic Disorders Observed in Infants with Severe Wasting at the Yalgado Ouedraogo teaching Hospital and the Charles de Gaulle Pediatric teaching Hospital in Ouagadougou, Burkina Faso

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Advances in Biological Chemistry 2023年第6期13卷 247-255页

作者： Arnaud Kouraogo Fabienne Soudre Caroline Yonaba Okengo Faouziatou Yagui Angele Kalmogho Ghislaine Yameogo Alice Kiba Raoul Karfo Ollo Da Emmanuel Zongo cherileila t.iombiano Fatou Gueye tall Abdoul Salam Ouédraogo Sanata Bamba Georges Anicet Ouédraogo Elie Kabré Fla Koueta Jean Sakande Biochemistry Laboratory of Souro Sanou teaching Hospital Nazi Boni University Bobo-Dioulasso Burkina Faso Health Sciences training and Research Unit Joseph Ki-Zerbo University Ouagadougou Burkina Faso Department of Pharmaceutical Biochemistry Faculty of Medicine Pharmacy and Dentistry Cheikh Anta Diop University Dakar Senegal

Introduction: A higher risk of death is associated with wasting in children if it is not treated properly. the objective of this study was to investigate the ionic disorders observed in infants suffering from severe wasting at Yalgado Ouedraogo teaching Hospital (YO-tH) and at Charles de Gaulle Pediatric teaching Hospital (CDG-PtH) in Ouagadougou (Burkina Faso). Methods: this was a retrospective study with a descriptive and analytical aim over the period from January 1, 2016 to December 31, 2020. Results: It concerned infants aged 6 to 24 months hospitalized at YO-tH and at CDG-PtH from Ouagadougou. We included 271 infants. the mean age of the infants was 14.48 ± 5.44 months with 42.07% which was in the age range of [12 - 18] months. On admission to the hospital, the children had an average weight, height and BMI of 6.22 ± 1.32 kg, 0.73 ± 0.07 m and 11.67 ± 1.53 kg/m2. In urban areas 56.46% of children and the main reasons for consultation were fever (88.19%), vomiting (52.80%) and diarrhea (50.20%). Electrolyte disturbances in emaciated infants affected all 8 parameters of the blood ionogram. However, the major disorders were 65.68% hyponatremia, 55.35% hypobicarbonatemia, 41.33% hypoprotidemia and 32.47% hypokalemia in infants aged 6 to 24 months. We found an association between diarrhea and residence with hypokalemia (p = 0.0000) and hypochloremia (p = 0.010), respectively. Conclusion: Severe acute wasting in infants 6 to 24 months of age remains a concern in the hospital setting. the frequency of biochemical disturbances is also high.

关键词： Severe Wasting Emaciation Infants over 6 - 24 Months Blood Ionogram Burkina Faso

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Ionic Disorders Observed in Infants with Severe Wasting at the Yalgado Ouedraogo teaching Hospital and the Charles de Gaulle Pediatric teaching Hospital in Ouagadougou, Burkina Faso

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Advances in Biological Chemistry（生物化学进展） 2023年第6期

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